Requirement of open headpiece conformation for activation of leukocyte integrin αXβ2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 33, 2010, Pages 14727-14732

  Chen, Xing ^a   Xie, Can ^a   Nishida, Noritaka ^a,c   Li, Zongli ^b   Walz, Thomas ^b   Springer, Timothy A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P 15095; IMMUNOGLOBULIN F(AB) FRAGMENT; INTEGRIN; MONOCLONAL ANTIBODY; LIGAND;

ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ELECTRON MICROSCOPY; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; BINDING SITE; CELL ADHESION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IMMUNOLOGY; LEUKOCYTE; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; BINDING SITES; CELL ADHESION; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTEGRIN ALPHAXBETA2; LEUKOCYTES; LIGANDS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 77957034686     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1008663107     Document Type: Article

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