A novel bidirectional positive-feedback loop between Wnt-β-catenin and EGFR-ERK plays a role in context-specific modulation of epithelial tissue regeneration

Journal of Cell Science

Volumn 127, Issue 13, 2014, Pages 2967-2982

  Georgopoulos, Nikolaos T ^a,b   Kirkwood, Lisa A ^a   Southgate, Jennifer ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

AKT; Crosstalk; EGFR; ERK; Wnt; catenin

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; CTNNB1 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; WNT PROTEIN;

ARTICLE; CELL ACTIVATION; CELL CONTACT; CELL GROWTH; CELL JUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; NEGATIVE FEEDBACK; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; SAOS 2 CELL LINE; TISSUE REGENERATION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; CELL LINE; METABOLISM; PHYSIOLOGY; REGENERATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BETA CATENIN; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; EPITHELIUM; HUMANS; MAP KINASE SIGNALING SYSTEM; RECEPTOR, EPIDERMAL GROWTH FACTOR; REGENERATION; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84903761963     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.150888     Document Type: Article

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