메뉴 건너뛰기




Volumn 12, Issue 4, 2007, Pages 521-534

Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; BREFELDIN A; CYSTEINE; FRIZZLED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PALMITIC ACID; WNT3A PROTEIN;

EID: 33947612673     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2007.01068.x     Document Type: Article
Times cited : (167)

References (40)
  • 1
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Bänziger, C., Soldini, D., Schütt, C., Zipperlen, P., Hausmann, G. & Basler, K. (2006) Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125, 509-522.
    • (2006) Cell , vol.125 , pp. 509-522
    • Bänziger, C.1    Soldini, D.2    Schütt, C.3    Zipperlen, P.4    Hausmann, G.5    Basler, K.6
  • 2
    • 0029150726 scopus 로고
    • Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties
    • Burrus, L.W. & McMahon, A.P. (1995) Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp. Cell Res. 220, 363-373.
    • (1995) Exp. Cell Res. , vol.220 , pp. 363-373
    • Burrus, L.W.1    McMahon, A.P.2
  • 3
    • 8444223093 scopus 로고    scopus 로고
    • Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
    • Cong, F., Schweizer, L. & Varmus, H. (2004) Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131, 5103-5115.
    • (2004) Development , vol.131 , pp. 5103-5115
    • Cong, F.1    Schweizer, L.2    Varmus, H.3
  • 4
    • 0032546946 scopus 로고    scopus 로고
    • A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21 RAS
    • Duncan, J.A. & Gilman, A.G. (1998) A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21 RAS. J. Biol. Chem. 273, 15830-15837.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15830-15837
    • Duncan, J.A.1    Gilman, A.G.2
  • 5
    • 0032497835 scopus 로고    scopus 로고
    • Signalling functions of protein palmitoylation
    • Dunphy, J.T. & Linder, M.E. (1998) Signalling functions of protein palmitoylation. Biochim. Biophys. Acta 1436, 245-261.
    • (1998) Biochim. Biophys. Acta , vol.1436 , pp. 245-261
    • Dunphy, J.T.1    Linder, M.E.2
  • 6
    • 33746587831 scopus 로고    scopus 로고
    • Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase
    • Fernandez-Hernando, C., Fukata, M., Bernatchez, P.N., Fukata, Y., Lin, M.I., Bredt, D.S. & Sessa, W.C. (2006) Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. J. Cell Biol. 174, 369-377.
    • (2006) J. Cell Biol. , vol.174 , pp. 369-377
    • Fernandez-Hernando, C.1    Fukata, M.2    Bernatchez, P.N.3    Fukata, Y.4    Lin, M.I.5    Bredt, D.S.6    Sessa, W.C.7
  • 8
    • 0037439138 scopus 로고    scopus 로고
    • Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
    • Habas, R., Dawid, I.B. & He, X. (2003) Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev. 17, 295-309.
    • (2003) Genes Dev. , vol.17 , pp. 295-309
    • Habas, R.1    Dawid, I.B.2    He, X.3
  • 9
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way
    • He, X., Semënov, M., Tamai, K. & Zeng, X. (2004) LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: arrows point the way. Development 131, 1663-1677.
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semënov, M.2    Tamai, K.3    Zeng, X.4
  • 10
    • 0035937505 scopus 로고    scopus 로고
    • Intracellular functions of N-linked glycans
    • Helenius, A. & Aebi, M. (2001) Intracellular functions of N-linked glycans. Science 291, 2364-2369.
    • (2001) Science , vol.291 , pp. 2364-2369
    • Helenius, A.1    Aebi, M.2
  • 11
    • 0027368963 scopus 로고
    • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
    • van den Heuvel, M., Harryman-Samos, C., Klingensmith, J., Perrimon, N. & Nusse, R. (1993) Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J. 12, 5293-5302.
    • (1993) EMBO J. , vol.12 , pp. 5293-5302
    • van den Heuvel, M.1    Harryman-Samos, C.2    Klingensmith, J.3    Perrimon, N.4    Nusse, R.5
  • 12
    • 0034161499 scopus 로고    scopus 로고
    • A superfamily of membrane-bound O -acyltransferases with implications for Wnt signaling
    • Hofmann, K. (2000) A superfamily of membrane-bound O -acyltransferases with implications for Wnt signaling. Trends Biochem. Sci. 25, 111-112.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 111-112
    • Hofmann, K.1
  • 13
    • 0037093315 scopus 로고    scopus 로고
    • T-cell factors: Turn-ons and turn-offs
    • Hurlstone, A. & Clevers, H. (2002) T-cell factors: Turn-ons and turn-offs. EMBO J. 21, 2303-2311.
    • (2002) EMBO J. , vol.21 , pp. 2303-2311
    • Hurlstone, A.1    Clevers, H.2
  • 14
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S. & Kikuchi, A. (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J. 17, 1371-1384.
    • (1998) EMBO J. , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 15
    • 0032727842 scopus 로고    scopus 로고
    • Effect of N -linked glycosylation on glycopeptide and glycoprotein structure
    • Imperiali, B. & O'Connor, S.E. (1999) Effect of N -linked glycosylation on glycopeptide and glycoprotein structure. Curr. Opin. Chem. Biol. 3, 643-649.
    • (1999) Curr. Opin. Chem. Biol. , vol.3 , pp. 643-649
    • Imperiali, B.1    O'Connor, S.E.2
  • 16
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano, Y. & Kypta, R. (2003) Secreted antagonists of the Wnt signalling pathway. J. Cell Sci. 116, 2627-2634.
    • (2003) J. Cell Sci. , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 17
    • 0032756584 scopus 로고    scopus 로고
    • Roles of Axin in the Wnt signalling pathway
    • Kikuchi, A. (1999) Roles of Axin in the Wnt signalling pathway. Cell. Signal. 11, 777-788.
    • (1999) Cell. Signal. , vol.11 , pp. 777-788
    • Kikuchi, A.1
  • 19
    • 2942592798 scopus 로고    scopus 로고
    • Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase
    • Kishida, S., Yamamoto, H. & Kikuchi, A. (2004) Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase. Mol. Cell. Biol. 24, 4487-4501.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4487-4501
    • Kishida, S.1    Yamamoto, H.2    Kikuchi, A.3
  • 20
    • 0026561901 scopus 로고
    • Brefeldin A: Insights into the control of membrane traffic and organelle structure
    • Klausner, R.D., Donaldson, J.G. & Lippincott-Schwartz, J. (1992) Brefeldin A: Insights into the control of membrane traffic and organelle structure. J. Cell Biol. 116, 1071-1080.
    • (1992) J. Cell Biol. , vol.116 , pp. 1071-1080
    • Klausner, R.D.1    Donaldson, J.G.2    Lippincott-Schwartz, J.3
  • 21
    • 33947213491 scopus 로고    scopus 로고
    • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signaling
    • in press
    • Kurayoshi, M., Yamamoto, H., Izumi, S. & Kikuchi, A. (2007) Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signaling. Biochem. J. in press.
    • (2007) Biochem. J.
    • Kurayoshi, M.1    Yamamoto, H.2    Izumi, S.3    Kikuchi, A.4
  • 22
    • 0024591235 scopus 로고
    • Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
    • Lippincott-Schwartz, J., Yuan, L.C., Bonifacino, J.S. & Klausner, R.D. (1989) Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER. Cell 56, 801-813.
    • (1989) Cell , vol.56 , pp. 801-813
    • Lippincott-Schwartz, J.1    Yuan, L.C.2    Bonifacino, J.S.3    Klausner, R.D.4
  • 23
    • 0027097821 scopus 로고
    • Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line
    • Mason, J.O., Kitajewski, J. & Varmus, H.E. (1992) Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Mol. Biol. Cell 3, 521-533.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 521-533
    • Mason, J.O.1    Kitajewski, J.2    Varmus, H.E.3
  • 24
    • 0037118279 scopus 로고    scopus 로고
    • Regulation of bone formation and vision by LRP5
    • Patel, M.S. & Karsenty, G. (2002) Regulation of bone formation and vision by LRP5. N. Engl. J. Med. 346, 1572-1574.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1572-1574
    • Patel, M.S.1    Karsenty, G.2
  • 25
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P. (2000) Wnt signaling and cancer. Genes Dev. 14, 1837-1851.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 27
    • 33645732587 scopus 로고    scopus 로고
    • Internalization is required for proper Wingless signaling in Drosophila melanogaster
    • Seto, E.S. & Bellen, H.J. (2006) Internalization is required for proper Wingless signaling in Drosophila melanogaster. J. Cell Biol. 173, 95-106. Internalization is required for proper Wingless signaling in Drosophila melanogaster
    • (2006) J. Cell Biol. , vol.173 , pp. 95-106
    • Seto, E.S.1    Bellen, H.J.2
  • 28
    • 0027752991 scopus 로고
    • Wnt family proteins are secreted and associated with the cell surface
    • Smolich, B.D., McMahon, J.A., McMahon, A.P. & Papkoff, J. (1993) Wnt family proteins are secreted and associated with the cell surface. Mol. Biol. Cell 4, 1267-1275.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1267-1275
    • Smolich, B.D.1    McMahon, J.A.2    McMahon, A.P.3    Papkoff, J.4
  • 31
    • 0037066744 scopus 로고    scopus 로고
    • Drosophila segment polarity gene product porcupine stimulates the posttranslational N -glycosylation of wingless in the endoplasmic reticulum
    • Tanaka, K., Kitagawa, Y. & Kadowaki, T. (2002) Drosophila segment polarity gene product porcupine stimulates the posttranslational N -glycosylation of wingless in the endoplasmic reticulum. J. Biol. Chem. 277, 12816-12823.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12816-12823
    • Tanaka, K.1    Kitagawa, Y.2    Kadowaki, T.3
  • 32
    • 2142790592 scopus 로고    scopus 로고
    • The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family
    • Tanaka, K., Okabayashi, K., Asashima, M., Perrimon, N. & Kadowaki, T. (2000) The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur. J. Biochem. 267, 4300-4311.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 4300-4311
    • Tanaka, K.1    Okabayashi, K.2    Asashima, M.3    Perrimon, N.4    Kadowaki, T.5
  • 33
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling
    • Veeman, M.T., Axelrod, J.D. & Moon, R.T. (2003) A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev. Cell 5, 367-377.
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 34
    • 0038343926 scopus 로고    scopus 로고
    • Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum
    • Waugh, M.G., Minogue, S., Anderson, J.S., Balinger, A., Blumenkrantz, D., Calnan, D.P., Cramer, R. & Hsuan, J.J. (2003) Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/ valosin-containing-protein-rich fraction of the endoplasmic reticulum. Biochem. J. 373, 57-63.
    • (2003) Biochem. J. , vol.373 , pp. 57-63
    • Waugh, M.G.1    Minogue, S.2    Anderson, J.S.3    Balinger, A.4    Blumenkrantz, D.5    Calnan, D.P.6    Cramer, R.7    Hsuan, J.J.8
  • 35
    • 0034614557 scopus 로고    scopus 로고
    • Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids
    • Webb, Y., Hermida-Matsumoto, L. & Resh, M.D. (2000) Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids. J. Biol. Chem. 275, 261-270.
    • (2000) J. Biol. Chem. , vol.275 , pp. 261-270
    • Webb, Y.1    Hermida-Matsumoto, L.2    Resh, M.D.3
  • 37
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz, A. & Nusse, R. (1998) Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14, 59-88.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 38
    • 0038558190 scopus 로고    scopus 로고
    • Sumoylation is involved in β-catenin-dependent activation of Tcf-4
    • Yamamoto, H., Ihara, M., Matsuura, Y. & Kikuchi, A. (2003) Sumoylation is involved in β-catenin-dependent activation of Tcf-4. EMBO J. 22, 2047-2059.
    • (2003) EMBO J. , vol.22 , pp. 2047-2059
    • Yamamoto, H.1    Ihara, M.2    Matsuura, Y.3    Kikuchi, A.4
  • 39
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin
    • Yamamoto, H., Komekado, H. & Kikuchi, A. (2006) Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin. Dev. Cell 11, 213-223.
    • (2006) Dev. Cell , vol.11 , pp. 213-223
    • Yamamoto, H.1    Komekado, H.2    Kikuchi, A.3
  • 40
    • 4043154959 scopus 로고    scopus 로고
    • Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
    • Zhai, L., Chaturvedi, D. & Cumberledge, S. (2004) Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J. Biol. Chem. 279, 33220-33227.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33220-33227
    • Zhai, L.1    Chaturvedi, D.2    Cumberledge, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.