메뉴 건너뛰기




Volumn 303, Issue 1, 2005, Pages 32-46

Cross-talk between pRb/E2F and Wnt/β-catenin pathways: E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death

Author keywords

Axin2; Cell death; E2F1; Wnt

Indexed keywords

AXIN; BETA CATENIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; WNT PROTEIN;

EID: 9644265161     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.09.014     Document Type: Article
Times cited : (38)

References (67)
  • 1
    • 0036897835 scopus 로고    scopus 로고
    • A revised picture of the E2F transcriptional network and RB function
    • O. Stevaux, and N.J. Dyson A revised picture of the E2F transcriptional network and RB function Curr. Opin. Cell Biol. 14 2002 684 691
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 684-691
    • Stevaux, O.1    Dyson, N.J.2
  • 2
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • S. Ishida, E. Huang, H. Zuzan, R. Spang, G. Leone, W. West, and J.R. Nevins Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis Mol. Cell. Biol. 21 2001 4684 4699
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3    Spang, R.4    Leone, G.5    West, W.6    Nevins, J.R.7
  • 10
    • 0029049577 scopus 로고
    • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
    • J. DeGregori, T. Kowalik, and J.R. Nevins Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes Mol. Cell. Biol. 15 1995 4215 4224 (Erratum in: Mol. Cell. Biol. 15 (1995) 5846-5847)
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4215-4224
    • Degregori, J.1    Kowalik, T.2    Nevins, J.R.3
  • 11
    • 0037445901 scopus 로고    scopus 로고
    • E2F and cell cycle control: A double-edged sword
    • C. Stevens, and N.B. La Thangue E2F and cell cycle control: a double-edged sword Arch. Biochem. Biophys. 412 2003 157 169
    • (2003) Arch. Biochem. Biophys. , vol.412 , pp. 157-169
    • Stevens, C.1    La Thangue, N.B.2
  • 12
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • D.G. Johnson, J.K. Schwarz, W.D. Cress, and J.R. Nevins Expression of transcription factor E2F1 induces quiescent cells to enter S phase Nature 365 1993 349 532
    • (1993) Nature , vol.365 , pp. 349-532
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 13
    • 0030053130 scopus 로고    scopus 로고
    • Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression
    • J. Lukas, B.O. Petersen, K. Holm, J. Bartek, and K. Helin Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression Mol. Cell. Biol. 16 1996 1047 1057
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1047-1057
    • Lukas, J.1    Petersen, B.O.2    Holm, K.3    Bartek, J.4    Helin, K.5
  • 14
    • 0037010122 scopus 로고    scopus 로고
    • E2F1 pathways to apoptosis
    • D. Ginsberg E2F1 pathways to apoptosis FEBS Lett. 529 2002 122 125
    • (2002) FEBS Lett. , vol.529 , pp. 122-125
    • Ginsberg, D.1
  • 16
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • T.F. Kowalik, J. DeGregori, J.K. Schwarz, and J.R. Nevins E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis J. Virol. 69 1995 2491 2500
    • (1995) J. Virol. , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    Degregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 19
    • 0742281301 scopus 로고    scopus 로고
    • E2F and Ras synergize in transcriptionally activating p14ARF expression
    • E. Berkovich, Y. Lamed, and D. Ginsberg E2F and Ras synergize in transcriptionally activating p14ARF expression Cell Cycle 2 2003 127 133
    • (2003) Cell Cycle , vol.2 , pp. 127-133
    • Berkovich, E.1    Lamed, Y.2    Ginsberg, D.3
  • 21
    • 0034056483 scopus 로고    scopus 로고
    • A role for E2F1 in the induction of apoptosis during thymic negative selection
    • I. Garcia, M. Murga, A. Vicario, S.J. Field, and A.M. Zubiaga A role for E2F1 in the induction of apoptosis during thymic negative selection Cell Growth Differ. 11 2000 91 98
    • (2000) Cell Growth Differ. , vol.11 , pp. 91-98
    • Garcia, I.1    Murga, M.2    Vicario, A.3    Field, S.J.4    Zubiaga, A.M.5
  • 23
    • 0037387386 scopus 로고    scopus 로고
    • Wnt-frizzled signaling in the induction and differentiation of the neural crest
    • W. Yanfeng, J.P. Saint-Jeannet, and P.S. Klein Wnt-frizzled signaling in the induction and differentiation of the neural crest BioEssays 25 2003 317 325
    • (2003) BioEssays , vol.25 , pp. 317-325
    • Yanfeng, W.1    Saint-Jeannet, J.P.2    Klein, P.S.3
  • 24
    • 0036236572 scopus 로고    scopus 로고
    • WNT signaling and lymphocyte development
    • M. van de Wetering, W. de Lau, and H. Clevers WNT signaling and lymphocyte development Cell 109 2002 S13 S19
    • (2002) Cell , vol.109
    • Van De Wetering, M.1    De Lau, W.2    Clevers, H.3
  • 25
    • 0036435260 scopus 로고    scopus 로고
    • Wnt signalling during limb development
    • V.L. Church, and P. Francis-West Wnt signalling during limb development Int. J. Dev. Biol. 46 2002 927 936
    • (2002) Int. J. Dev. Biol. , vol.46 , pp. 927-936
    • Church, V.L.1    Francis-West, P.2
  • 26
    • 0038274074 scopus 로고    scopus 로고
    • Stem cells in the skin: Waste not, Wnt not
    • L. Alonso, and E. Fuchs Stem cells in the skin: waste not, Wnt not Genes Dev. 17 2003 1189 1200
    • (2003) Genes Dev. , vol.17 , pp. 1189-1200
    • Alonso, L.1    Fuchs, E.2
  • 27
    • 0036066584 scopus 로고    scopus 로고
    • Gastrointestinal stem cells
    • M. Brittan, and N.A. Wright Gastrointestinal stem cells J. Pathol. 197 2002 492 509
    • (2002) J. Pathol. , vol.197 , pp. 492-509
    • Brittan, M.1    Wright, N.A.2
  • 28
    • 0038359353 scopus 로고    scopus 로고
    • Caught up in a Wnt storm: Wnt signaling in cancer
    • R.H. Giles, and H. Clevers Caught up in a Wnt storm: Wnt signaling in cancer Biochim. Biophys. Acta 1653 2003 1 24
    • (2003) Biochim. Biophys. Acta , vol.1653 , pp. 1-24
    • Giles, R.H.1    Clevers, H.2
  • 29
    • 0036124896 scopus 로고    scopus 로고
    • TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling
    • H. Brantjes, N. Barker, and H. Clevers TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling Biol. Chem. 383 2002 255 261
    • (2002) Biol. Chem. , vol.383 , pp. 255-261
    • Brantjes, H.1    Barker, N.2    Clevers, H.3
  • 31
    • 0037077266 scopus 로고    scopus 로고
    • Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling
    • J.Y. Leung, F.T. Kolligs, R. Wu, Y. Zhai, R. Kuick, S. Hanash, K.R. Cho, and E.R. Fearon Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling J. Biol. Chem. 277 2002 21657 21665
    • (2002) J. Biol. Chem. , vol.277 , pp. 21657-21665
    • Leung, J.Y.1    Kolligs, F.T.2    Wu, R.3    Zhai, Y.4    Kuick, R.5    Hanash, S.6    Cho, K.R.7    Fearon, E.R.8
  • 32
    • 0029924478 scopus 로고    scopus 로고
    • B-myb promotes S phase and is a downstream target of the negative regulator p107 in human cells
    • A. Sala, I. Casella, T. Bellon, B. Calabretta, R.J. Watson, and C. Peschle B-myb promotes S phase and is a downstream target of the negative regulator p107 in human cells J. Biol. Chem. 271 1996 9363 9367
    • (1996) J. Biol. Chem. , vol.271 , pp. 9363-9367
    • Sala, A.1    Casella, I.2    Bellon, T.3    Calabretta, B.4    Watson, R.J.5    Peschle, C.6
  • 33
    • 0028577898 scopus 로고
    • Identifying differences in mRNA expression by representational difference analysis of cDNA
    • M. Hubank, and D.G. Schatz Identifying differences in mRNA expression by representational difference analysis of cDNA Nucleic Acids Res. 22 1994 5640 5648
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5640-5648
    • Hubank, M.1    Schatz, D.G.2
  • 34
    • 0032989131 scopus 로고    scopus 로고
    • CDNA representational difference analysis: A sensitive and flexible method for identification of differentially expressed genes
    • M. Hubank, and D.G. Schatz cDNA representational difference analysis: a sensitive and flexible method for identification of differentially expressed genes Methods Enzymol. 303 1999 325 349
    • (1999) Methods Enzymol. , vol.303 , pp. 325-349
    • Hubank, M.1    Schatz, D.G.2
  • 35
    • 0029002136 scopus 로고
    • A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
    • T.D. Littlewood, D.C. Hancock, P.S. Danielian, M.G. Parker, and G.I. Evan A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins Nucleic Acids Res. 23 1995 1686 1690
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1686-1690
    • Littlewood, T.D.1    Hancock, D.C.2    Danielian, P.S.3    Parker, M.G.4    Evan, G.I.5
  • 36
    • 0027442926 scopus 로고
    • A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4
    • W.D. Cress, D.G. Johnson, and J.R. Nevins A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4 Mol. Cell. Biol. 13 1993 6314 6325
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6314-6325
    • Cress, W.D.1    Johnson, D.G.2    Nevins, J.R.3
  • 38
    • 0034908622 scopus 로고    scopus 로고
    • Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene
    • X. Dong, R.S. Seelan, C. Qian, M. Mai, and W. Liu Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene Cytogenet. Cell Genet. 93 2001 26 28
    • (2001) Cytogenet. Cell Genet. , vol.93 , pp. 26-28
    • Dong, X.1    Seelan, R.S.2    Qian, C.3    Mai, M.4    Liu, W.5
  • 39
    • 0038074398 scopus 로고    scopus 로고
    • HMG box transcription factor TCF-4's interaction with CtBP1 controls expression of the Wnt target axin2/conductin in human embryonic kidney cells
    • T. Valenta, J. Lukas, and V. Korinek HMG box transcription factor TCF-4's interaction with CtBP1 controls expression of the Wnt target axin2/conductin in human embryonic kidney cells Nucleic Acids Res. 31 2003 2369 2380
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2369-2380
    • Valenta, T.1    Lukas, J.2    Korinek, V.3
  • 40
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • E.H. Jho, T. Zhang, C. Domon, C.K. Joo, J.N. Freund, and F. Costantini Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway Mol. Cell. Biol. 22 2002 1172 1183
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 42
    • 0024318029 scopus 로고
    • Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo
    • M.C. Blake, and J.C. Azizkhan Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo Mol. Cell. Biol. 9 1989 4994 5002
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4994-5002
    • Blake, M.C.1    Azizkhan, J.C.2
  • 43
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • E.W. Lam, and R.J. Watson An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription EMBO J. 12 1993 2705 2713
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.1    Watson, R.J.2
  • 44
    • 0037008667 scopus 로고    scopus 로고
    • A 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinase
    • M. Yamada, N. Sato, C. Taniyama, K. Ohtani, K. Arai, and H. Masai A 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinase J. Biol. Chem. 277 2002 27668 27681
    • (2002) J. Biol. Chem. , vol.277 , pp. 27668-27681
    • Yamada, M.1    Sato, N.2    Taniyama, C.3    Ohtani, K.4    Arai, K.5    Masai, H.6
  • 45
    • 0028136903 scopus 로고
    • Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter
    • E. Neuman, E.K. Flemington, W.R. Sellers, and W.G. Kaelin Jr. Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter Mol. Cell. Biol. 14 1994 6607 6615
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6607-6615
    • Neuman, E.1    Flemington, E.K.2    Sellers, W.R.3    Kaelin Jr., W.G.4
  • 46
    • 0034175616 scopus 로고    scopus 로고
    • Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression
    • Y. Takahashi, J.B. Rayman, and B.D. Dynlacht Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression Genes Dev. 14 2000 804 816
    • (2000) Genes Dev. , vol.14 , pp. 804-816
    • Takahashi, Y.1    Rayman, J.B.2    Dynlacht, B.D.3
  • 47
    • 0033194431 scopus 로고    scopus 로고
    • Modulation of Wnt signaling by Axin and Axi
    • A. Kikuchi Modulation of Wnt signaling by Axin and Axi Cytokine Growth Factor Rev. 10 1999 255 265
    • (1999) Cytokine Growth Factor Rev. , vol.10 , pp. 255-265
    • Kikuchi, A.1
  • 51
    • 0036106013 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling suppresses apoptosis in low serum medium and induces morphologic change in rodent fibroblasts
    • Y. Ueda, M. Hijikata, S. Takagi, R. Takada, S. Takada, T. Chiba, and K. Shimotohno Wnt/beta-catenin signaling suppresses apoptosis in low serum medium and induces morphologic change in rodent fibroblasts Int. J. Cancer 99 2002 681 688
    • (2002) Int. J. Cancer , vol.99 , pp. 681-688
    • Ueda, Y.1    Hijikata, M.2    Takagi, S.3    Takada, R.4    Takada, S.5    Chiba, T.6    Shimotohno, K.7
  • 53
    • 0042337365 scopus 로고    scopus 로고
    • Differential regulation of p63 and p73 expression
    • A. Waltermann, N.N. Kartasheva, and M. Dobbelstein Differential regulation of p63 and p73 expression Oncogene 22 2003 5686 5693
    • (2003) Oncogene , vol.22 , pp. 5686-5693
    • Waltermann, A.1    Kartasheva, N.N.2    Dobbelstein, M.3
  • 54
    • 0344441259 scopus 로고    scopus 로고
    • Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter
    • K. Araki, Y. Nakajima, K. Eto, and M.A. Ikeda Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter Oncogene 22 2003 7632 7641
    • (2003) Oncogene , vol.22 , pp. 7632-7641
    • Araki, K.1    Nakajima, Y.2    Eto, K.3    Ikeda, M.A.4
  • 55
    • 85047698254 scopus 로고    scopus 로고
    • A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4
    • R. Croxton, Y. Ma, and W.D. Cress A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4 Oncogene 21 2002 1563 1570
    • (2002) Oncogene , vol.21 , pp. 1563-1570
    • Croxton, R.1    Ma, Y.2    Cress, W.D.3
  • 56
    • 0035946917 scopus 로고    scopus 로고
    • Computer-assisted identification of cell cycle-related genes: New targets for E2F transcription factors
    • A.E. Kel, O.V. Kel-Margoulis, P.J. Farnham, S.M. Bartley, E. Wingender, and M.Q. Zhang Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors J. Mol. Biol. 309 2001 99 120
    • (2001) J. Mol. Biol. , vol.309 , pp. 99-120
    • Kel, A.E.1    Kel-Margoulis, O.V.2    Farnham, P.J.3    Bartley, S.M.4    Wingender, E.5    Zhang, M.Q.6
  • 58
    • 0142254155 scopus 로고    scopus 로고
    • A transcriptional response to Wnt protein in human embryonic carcinoma cells
    • J. Willert, M. Epping, J.R. Pollack, P.O. Brown, and R. Nusse A transcriptional response to Wnt protein in human embryonic carcinoma cells BMC Dev. Biol. 2 2002 8
    • (2002) BMC Dev. Biol. , vol.2 , pp. 8
    • Willert, J.1    Epping, M.2    Pollack, J.R.3    Brown, P.O.4    Nusse, R.5
  • 59
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • M. Classon, and E. Harlow The retinoblastoma tumour suppressor in development and cancer Nat. Rev., Cancer 2 2002 910 917
    • (2002) Nat. Rev., Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 60
  • 61
    • 0036174452 scopus 로고    scopus 로고
    • β-catenin-A linchpin in colorectal carcinogenesis?
    • N.A.C.S. Wong, and M. Pignatelli β-catenin-A linchpin in colorectal carcinogenesis? Am. J. Pathol. 160 2002 389 401
    • (2002) Am. J. Pathol. , vol.160 , pp. 389-401
    • Wong, N.A.C.S.1    Pignatelli, M.2
  • 63
  • 64
    • 0343196653 scopus 로고    scopus 로고
    • Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions
    • M. Barlund, M. Tirkkonen, F. Forozan, M.M. Tanner, O. Kallioniemi, and A. Kallioniemi Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions Genes Chromosomes Cancer 20 1997 372 376
    • (1997) Genes Chromosomes Cancer , vol.20 , pp. 372-376
    • Barlund, M.1    Tirkkonen, M.2    Forozan, F.3    Tanner, M.M.4    Kallioniemi, O.5    Kallioniemi, A.6
  • 67
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • G. Bergers, and L.E. Benjamin Tumorigenesis and the angiogenic switch Nat. Rev., Cancer 3 2003 401 410
    • (2003) Nat. Rev., Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.