Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels bv VEGF withdrawal

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 16, 1997, Pages 8761-8766

  Benjamin, Laura E ^a   Keshet, Eli ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Hemorrhage; Neovascularization; Tetracycline inducible expression; Vessel regression

Indexed keywords

VASCULOTROPIN;

ANIMAL CELL; ARTICLE; HEMANGIOBLASTOMA; MOUSE; NECROSIS; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS REGULATION; TUMOR VASCULARIZATION;

ANIMALS; CELL LINE; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HEMANGIOBLASTOMA; LYMPHOKINES; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN SYNTHESIS INHIBITORS; TETRACYCLINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA;

EID: 0030806273     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.16.8761     Document Type: Article

References (38)

1. Hanahan, D. & Folkman, J. (1996) Cell 86, 353-364.
2. Holmgren, L., O'Reilly, M. S. & Folkman, J. (1995) Nat. Med. 1, 149-153.
3. O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Cao, Y., Moses, M., Lane, W. S., Sage, E. H. & Folkman, J. (1994) Cold Spring Harbor Symp. Quant. Biol. 59, 471-482.
4. Mukhopadhyay, D., Tsiokas, L. & Sukhatme, V. P. (1995) Cancer Res. 55, 6161-6165.
5. Rak, J., Mitsuhashi, Y., Bayko, L., Filmus, J., Shirasawa, S., Sasazuki, T. & Kerbel, R. S. (1995) Cancer Res. 55, 4575-4580.
6. Grugel, S., Finkenzeller, G., Weindel, K., Barleon, B. & Marme, D. (1995) J. Biol. Chem. 270, 25915-25919.
7. Wizigmann Voos, S., Breier, G., Risau, W. & Plate, K. H. (1995) Cancer Res. 55, 1358-1364.
8. Kieser, A., Weich, H. A., Brandner, G., Marme, D. & Kolch, W. (1994) Oncogene 9, 963-969.
9. Shweiki, D., Itin, A., Soffer, D. & Keshet, E. (1992) Nature (London) 359, 843-845.
10. Plate, K. H., Breier, G., Weich, H. A. & Risau, W. (1992) Nature (London) 359, 845-848.
11. Shweiki, D., Neeman, M., Itin, A. & Keshet, E. (1995) Proc. Natl. Acad. Sci. USA 92, 768-772.
12. Zhang, H. T., Craft, P., Scott, P. A., Ziche, M., Weich, H. A., Harris, A. L. & Bicknell, R. (1995) J. Natl. Cancer Inst. 87, 213-219.
13. Takahashi, Y., Kitadai, Y., Bucana, C. D., Cleary, K. R. & Ellis, L. M. (1995) Cancer Res. 55, 3964-3968.
14. Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S. & Ferrara, N. (1993) Nature (London) 362, 841-844.
15. Millauer, B., Shawver, L. K., Plate, K. H., Risau, W. & Ullrich, A. (1994) Nature (London) 367, 576-579.
16. Millauer, B., Longhi, M. P., Plate, K. H., Shawver, L. K., Risau, W., Ullrich, A. & Strawn, L. M. (1996) Cancer Res. 56, 1615-1620.
17. Borgstrom, P., Hillan, K. J., Sriramarao, P. & Ferrara, N. (1996) Cancer Res. 56, 4032-4039.
18. Raff, M. C., Barres, B. A., Burne, J. F., Coles, H. S., Ishizaki, Y. & Jacobson, M. D. (1993) Science 262, 695-700.
19. Raff, M. C., Barres, B. A., Burne, J. F., Coles, H. S., Ishizaki, Y. & Jacobson, M. D. (1994) Philos. Trans. R. Soc. London B 345, 265-268.
20. Alon, T., Hemo, I., Itin, A., Pe'er, J., Stone, J. & Keshet, E. (1995) Nat. Med. 1024-1028.
21. Plate, K. H., Breier, G., Millauer, B., Ullrich, A. & Risau, W. (1993) Cancer Res. 53, 5822-5827.
22. Stein, I., Neeman, M., Shweiki, D., Itin, A. & Keshet, E. (1995) Mol. Cell. Biol. 15, 5363-5368.
23. Morii, K., Tanaka, R., Washiyama, K., Kumanishi, T. & Kuwano, R. (1993) Biochem. Biophys. Res. Commun. 194, 749-755.
24. Bohling, T., Hatva, E., Kujala, M., Claesson Welsh, L., Alitalo, K. & Haltia, M. (1996) J. Neuropathol. Exp. Neurol. 55, 522-527.
25. Re, F., Zanetti, A., Sironi, M., Polentarutti, N., Lanfrancone, L., Dejana, E. & Colotta, F. (1994) J. Cell Biol. 127, 537-546.
26. Trotter, M. J., Chaplin, D. J., Durand, R. E. & Olive, P. L. (1989) Int. J. Radiat. Oncol. Biol. Phys. 16, 931-945.
27. Chaplin, D. J., Olive, P. L. & Durand, R. E. (1987) Cancer Res. 47, 597-601.
28. Fox, S. B., Gatter, K. C., Bicknell, R., Going, J. J., Stanton, P., Cooke, T. G. & Harris, A. L. (1993) Cancer Res. 53, 4161-4163.
29. Drake, C. J. & Little, C. D. (1995) Proc. Natl. Acad. Sci. USA 92, 7657-7661.
30. Modlich, U., Kaup, F.-J. & Augustin, H. G. (1996) Lab. Invest. 74, 771-780.
31. Merdith, J. E. & Schwarz, M. A. (1997) Trends Cell Biol. 7, 146-150.
32. Merdith, J. E., Fazeli, B. & Schwartz, M. A. (1993) Mol. Biol. Cell. 4, 953-961.
33. Rak, J. & Kerbel, R. S. (1996) Cancer Metastasis Rev. 15, 231-236.
34. Barinaga, M. (1997) Science 275, 482-484.
35. Nagashima, T., Hoshino, T. & Cho, K. G. (1987) Acta Neuropathol. 73, 301-305.
36. Powell, P. P. & Klagsbrun, M. (1993) Exp. Cell Res. 209, 224-230.
37. Yuan, F., Chen, Y., Dellian, M., Safabakhsh, N., Ferrara, N. & Jain, R. (1996) Proc. Natl. Acad. Sci USA 93, 14765-14770.
38. Isner, J. M., Pieczek, A., Schainfeld, R., Blair, R., Haley, L., Asahara, T., Rosenfield, K., Razvi, S., Walsh, K. & Symes, J. F. (1996) Lancet 348, 370-374.