Endothelial growth factor receptors in human fetal heart

Circulation

Volumn 100, Issue 6, 1999, Pages 583-586

  Partanen, Taina A ^b   Makinen, Taija ^b   Arola, Johanna ^b   Suda, Toshio ^b   Weich, Herbert A ^b   Alitalo, Kari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NONE

Author keywords

Angiogenesis; Endocardium; Endothelium; Growth substances; Myocardium

Indexed keywords

ENDOTHELIAL CELL GROWTH FACTOR; GROWTH FACTOR RECEPTOR; NEUROPILIN; PROTEIN KINASE; PROTEIN TYROSINE KINASE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ARTICLE; CORONARY ARTERY; CORONARY VEIN; ENDOCARDIUM; EPICARDIUM; FETUS; FETUS HEART; GENE EXPRESSION; HEART MUSCLE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH VESSEL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECEPTOR DENSITY;

EID: 0033543126     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.100.6.583     Document Type: Article

References (20)

1. Korpelainen EI, Alitalo K. Signaling angiogenesis and lymphangiogenesis. Curr Opin Cell Biol. 1998;10:159-164.
2. Ferrara N. Vascular endothelial growth factor: molecular and biological aspects. Curr Top Microbiol Immunol. 1999;237:1-30.
3. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 1998;92:735-745.
4. Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H. Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development. 1995;121:4309-4318.
5. Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science. 1997;277: 55-60.
6. Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Yancopoulos GD. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1997;87:1161-1169.
7. Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach A, Brietman ML. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, Tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev. 1994;8:1897-1909.
8. Puri MC, Rossant J, Alitalo K, Bernstein A, Partanen J. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J. 1995;14:5884-5891.
9. Baumgartner I, Isner JM. Stimulation of peripheral angiogenesis by vascular endothelial growth factor. Vasa. 1998;27:201-206.
10. Asahara T, Chen D, Takahashi T, Fujikawa K, Keamey M, Magner M, Yancopoulos GD, Isner JM. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res. 1998;83:233-240.
11. Peters KG. Vascular endothelial growth factor and the angiopoietins: working together to build a better blood vessel. Circ Res. 1998;83: 342-343.
12. Jussila L, Valtola R, Partanen TA, Salvén P, Matikainen M-T, Renkonen R, Kaipainen A, Detmar M, Tschachler D, Alitalo R, Alitalo K. Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by anti-bodies against the vascular endothelial growth factor receptor 3. Cancer Res. 1998;58:1599-1604.
13. Simon M, Rockl W, Hornig C, Grone EF, Theis H, Weich HA, Fuchs E, Yayon A, Grone HJ. Receptors of vascular endothelial growth factor/ vascular permeability factor (VEGFWPF) in fetal and adult human kidney: localization and [I-125]VEGF-binding sites. J Am Soc Nephrol. 1998;9:1032-1044.
14. Salvén P, Joensuu H, Heikkilä P, Matikainen MT, Wasenius VM, Alanko A, Alitalo K. Endothelial Tie growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis. Br J Cancer. 1996; 74:69-72.
15. Maisonpierre PC, Goldfarb M, Yancopoulos GD, Gao G. Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family. Oncogene. 1993;8:1631-1637.
16. Kaipainen A, Korhonen J, Pajusola K, Aprelikova O, Persico MG, Terman BI, Alitalo K. The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression pattern in human fetal endothelial cells. J Exp Med. 1993;178:2077-2088.
17. Dumont DJ, Fong GH, Puri MC, Gradwohl G, Alitalo K, Breitman ML. Vascularization of the mouse embryo: a study of flk-1, tek, tie and vascular endothelial growth factor expression during development. Dev Dyn. 1995;203:80-92.
18. Peters KG, De Vries C, Williams LT. Vascular endothelial growth factor receptor expression during embryogenesis. Proc Natl Acad Sci USA. 1993;90:8915-8919.
19. Joukov V, Kumar V, Sorsa T, Arighi E, Weich H, Saksela O, Alitalo K. A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities. J Biol Chem. 1998;273: 6599-6602.
20. Dumont DJ, Jussila L, Taipale J, Lymboussaki A, Mustonen T, Pajusola K, Breitman M, Alitalo K. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science. 1998;282:946-949.