Placental growth factor is a survival factor for tumor endothelial cells and macrophages

Cancer Research

Volumn 62, Issue 10, 2002, Pages 2749-2752

  Adini, Avner ^a   Kornaga, Tad ^a   Firoozbakht, Farshid ^a   Benjamin, Laura E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; PLACENTAL GROWTH FACTOR; TETRACYCLINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA CONTENT; ENDOTHELIUM CELL; GENE EXPRESSION; GENE OVEREXPRESSION; GLIOMA CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CATTLE; CELL SURVIVAL; CHROMOSOMAL PROTEINS, NON-HISTONE; ENDOTHELIUM, VASCULAR; GLIOMA; HUMANS; MACROPHAGES; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PREGNANCY PROTEINS; RATS; UP-REGULATION;

EID: 0037093078     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
2. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the Serine/Threonine kinase Akt
3. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
4. Control of apoptosis during angiogenesis by survivin expression in endothelial cells
5. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and Ain vascular endothelial cells
6. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells
7. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
8. The contributions of cyclooxygenase-2 to tumor angiogenesis
9. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
10. Heterogeneity of angiogenesis and blood vessel maturation in human tumors: Implications for antiangiogenic tumor therapies
11. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
12. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
13. Structure, expression and receptor-binding properties of placenta growth factor (PlGF)
14. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
15. Placenta growth factor (P1GF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is coexpressed with VEGF in synovial fluid
16. Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers
17. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
18. Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans
19. Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues
20. Co-expression of vascular endothelial growth factor and its receptor flt-1 in malignant pleural mesothelioma