Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1D2: Recognition and specificity

Journal of Biological Chemistry

Volumn 285, Issue 31, 2010, Pages 23779-23789

  Iyer, Shalini ^a   Darley, Paula I ^a   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANGIOGENIC GROWTH FACTORS; CHRONIC INFLAMMATION; GROWTH FACTOR; PHYSIOLOGICAL PROCESS; RECEPTOR BINDING; RECEPTOR-LIGAND INTERACTIONS; SEQUENCE OF EVENTS; STRUCTURAL INSIGHTS; TISSUE REGENERATION; TUMOR PROGRESSIONS; TYROSINE KINASE; VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULOGENESIS; WOUND HEALING;

AMINO ACIDS; BINDING ENERGY; BINDING SITES; BIOACTIVITY; BIOCHEMISTRY; BLOOD; CRYSTAL STRUCTURE; LIGANDS; MOLECULES; PATHOLOGY; PEPTIDES; PHOSPHATASES; SELF ASSEMBLY;

BLOOD VESSELS;

VASCULOTROPIN B; VASCULOTROPIN RECEPTOR 1;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; LIGANDS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR ENDOTHELIAL GROWTH FACTOR B; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 77954912465     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.130658     Document Type: Article

References (44)

1. Folkman, J., and Shing, Y. (1992) J. Biol. Chem. 267, 10931-10934
2. Folkman, J. (1995) Nat. Med. 1, 27-31
3. Otrock, Z. K., Mahfouz, R. A., Makarem, J. A., and Shamseddine, A. I. (2007) Blood Cells Mol. Dis. 39, 212-220
4. Holmes, D. I., and Zachary, I. (2005) Genome Biol. 6, 209
5. Yamazaki, Y., and Morita, T. (2006) Mol. Divers. 10, 515-527
6. Stuttfeld, E., and Ballmer-Hofer, K. (2009) IUBMB Life 61, 915-922
7. Otrock, Z. K., Makarem, J. A., and Shamseddine, A. I. (2007) Blood Cells Mol. Dis. 38, 258-268
8. Neufeld, G., Lange, T., Varshavsky, A., and Kessler, O. (2007) Adv. Exp. Med. Biol. 600, 118-131
9. Mousa, S. A. (2007) Semin. Thromb. Hemost. 33, 524-533
10. Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V., Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K., and Eriksson, U. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 2576-2581
11. Lagercrantz, J., Farnebo, F., Larsson, C., Tvrdik, T., Weber, G., and Piehl, F. (1998) Biochim. Biophys. Acta 1398, 157-163
12. Aase, K., Lymboussaki, A., Kaipainen, A., Olofsson, B., Alitalo, K., and Eriksson, U. (1999) Dev. Dyn. 215, 12-25
13. Bellomo, D., Headrick, J. P., Silins, G. U., Paterson, C. A., Thomas, P. S., Gartside, M., Mould, A., Cahill, M. M., Tonks, I. D., Grimmond, S. M., Townson, S., Wells, C., Little, M., Cummings, M. C., Hayward, N. K., and Kay, G. F. (2000) Circ. Res. 86, E29-E35
14. Detoraki, A., Staiano, R. I., Granata, F., Giannattasio, G., Prevete, N., de Paulis, A., Ribatti, D., Genovese, A., Triggiani, M., and Marone, G. (2009) J. Allergy Clin. Immunol. 123, 1142-1149, 1149.e1-5
15. Zhang, F., Tang, Z., Hou, X., Lennartsson, J., Li, Y., Koch, A. W., Scotney, P., Lee, C., Arjunan, P., Dong, L., Kumar, A., Rissanen, T. T., Wang, B., Nagai, N., Fons, P., Fariss, R., Zhang, Y., Wawrousek, E., Tansey, G., Raber, J., Fong, G. H., Ding, H., Greenberg, D. A., Becker, K. G., Herbert, J. M., Nash, A., Yla-Herttuala, S., Cao, Y., Watts, R. J., and Li, X. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 6152-6157
16. Gunningham, S. P., Currie, M. J., Han, C., Robinson, B. A., Scott, P. A., Harris, A. L., and Fox, S. B. (2001) J. Pathol. 193, 325-332
17. Louzier, V., Raffestin, B., Leroux, A., Branellec, D., Caillaud, J. M., Levame, M., Eddahibi, S., and Adnot, S. (2003) Am. J. Physiol. Lung Cell Mol. Physiol. 284, L926-L937
18. Li, X., Aase, K., Li, H., von Euler, G., and Eriksson, U. (2001) Growth Factors 19, 49-59
19. Karpanen, T., Bry, M., Ollila, H. M., Seppänen-Laakso, T., Liimatta, E., Leskinen, H., Kivelä, R., Helkamaa, T., Merentie, M., Jeltsch, M., Paavonen, K., Andersson, L. C., Mervaala, E., Hassinen, I. E., Ylä-Herttuala, S., Oresic, M., and Alitalo, K. (2008) Circ. Res. 103, 1018-1026
20. Cao, Y., Chen, H., Zhou, L., Chiang, M. K., Anand-Apte, B., Weatherbee, J. A., Wang, Y., Fang, F., Flanagan, J. G., and Tsang, M. L. (1996) J. Biol. Chem. 271, 3154-3162
21. Olofsson, B., Korpelainen, E., Pepper, M. S., Mandriota, S. J., Aase, K., Kumar, V., Gunji, Y., Jeltsch, M. M., Shibuya, M., Alitalo, K., and Eriksson, U. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 11709-11714
22. Makinen, T., Olofsson, B., Karpanen, T., Hellman, U., Soker, S., Klagsbrun, M., Eriksson, U., and Alitalo, K. (1999) J. Biol. Chem. 274, 21217-21222
23. Yoon, Y. S., and Losordo, D. W. (2003) Circ. Res. 93, 87-90
24. Muller, Y. A., Christinger, H. W., Keyt, B. A., and de Vos, A. M. (1997) Structure 5, 1325-1338
25. Wiesmann, C., Fuh, G., Christinger, H. W., Eigenbrot, C., Wells, J. A., and de Vos, A. M. (1997) Cell 91, 695-704
26. Muller, Y. A., Chen, Y., Christinger, H. W., Li, B., Cunningham, B. C., Lowman, H. B., and de Vos, A. M. (1998) Structure 6, 1153-1167
27. Chen, Y., Wiesmann, C., Fuh, G., Li, B., Christinger, H. W., McKay, P., de Vos, A. M., and Lowman, H. B. (1999) J. Mol. Biol. 293, 865-881
28. Fuh, G., Wu, P., Liang, W. C., Ultsch, M., Lee, C. V., Moffat, B., and Wiesmann, C. (2006) J. Biol. Chem. 281, 6625-6631
29. Iyer, S., Leonidas, D. D., Swaminathan, G. J., Maglione, D., Battisti, M., Tucci, M., Persico, M. G., and Acharya, K. R. (2001) J. Biol. Chem. 276, 12153-12161
30. Iyer, S., Scotney, P. D., Nash, A. D., and Acharya, K. R. (2006) J. Mol. Biol. 359, 76-85
31. Christinger, H. W., Fuh, G., de Vos, A. M., and Wiesmann, C. (2004) J. Biol. Chem. 279, 10382-10388
32. Leonard, P., Scotney, P. D., Jabeen, T., Iyer, S., Fabri, L. J., Nash, A. D., and Acharya, K. R. (2008) J. Mol. Biol. 384, 1203-1217
33. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
34. Collaborative Computational Project, No. 4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
35. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
36. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
37. Scrofani, S. D., Fabri, L. J., Xu, P., Maccarone, P., and Nash, A. D. (2000) Protein Sci. 9, 2018-2025
38. Ramachandran, G. N., and Sasisekharan, V. (1968) Adv. Protein Chem. 23, 283-438
39. Keyt, B. A., Nguyen, H. V., Berleau, L. T., Duarte, C. M., Park, J., Chen, H., and Ferrara, N. (1996) J. Biol. Chem. 271, 5638-5646
40. Davis-Smyth, T., Presta, L. G., and Ferrara, N. (1998) J. Biol. Chem. 273, 3216-3222
41. Leppänen, V. M., Prota, A. E., Jeltsch, M., Anisimov, A., Kalkkinen, N., Strandin, T., Lankinen, H., Goldman, A., Ballmer-Hofer, K., and Alitalo, K. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 2425-2430
42. Scotney, P. D., MacKenzie, A., Maccarone, P., Fabri, L. J., Scrofani, S. D., Gooley, P. R., and Nash, A. D. (2002) Clin. Exp. Pharmacol. Physiol. 29, 1024-1029
43. Hagberg, C. E., Falkevall, A., Wang, X., Larsson, E., Huusko, J., Nilsson, I., van Meeteren, L. A., Samen, E., Lu, L., Vanwildemeersch, M., Klar, J., Genove, G., Pietras, K., Stone-Elander, S., Claesson-Welsh, L., Ylä-Herttuala, S., Lindahl, P., and Eriksson, U. (2010) Nature 464, 917-921
44. Kabsch, W., and Sander, C. (1983) Biopolymers 22, 2577-2637