The diabetes susceptibility gene Clec16a regulates mitophagy

Cell

Volumn 157, Issue 7, 2014, Pages 1577-1590

  Soleimanpour, Scott A ^a,b   Gupta, Aditi ^a   Bakay, Marina ^c   Ferrari, Alana M ^a   Groff, David N ^a   Fadista, João ^d   Spruce, Lynn A ^c   Kushner, Jake A ^e   Groop, Leif ^d   Seeholzer, Steven H ^c   Kaufman, Brett A ^f   Hakonarson, Hakon ^a,c   Stoffers, Doris A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CLEC16A PROTEIN; GLUCOSE; PARKIN; PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 NRDP1; UNCLASSIFIED DRUG; C TYPE LECTIN DOMAIN FAMILY 16 MEMBER A; INSULIN; LECTIN; MITOFUSIN 2; OXYGEN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE NRDP1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; CELL FUNCTION; CELL FUSION; CONTROLLED STUDY; DIABETOGENESIS; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE DELETION; GENETIC SUSCEPTIBILITY; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; IMPAIRED GLUCOSE TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; LYSOSOME; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOPHAGY; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; CELL VACUOLE; CELL VIABILITY; DIABETES MELLITUS; EMBRYO; ENDOSOME; FIBROBLAST; GENE EXPRESSION; GENETIC REGULATION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; HUMAN TISSUE; MOLECULAR PATHOLOGY; QUANTITATIVE TRAIT LOCUS;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LECTINS, C-TYPE; LYSOSOMES; MEMBRANE PROTEINS; MICE; MITOCHONDRIAL DEGRADATION; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84903196141     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.05.016     Document Type: Article

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