메뉴 건너뛰기




Volumn 26, Issue 6, 2012, Pages 725-738

Mitochondrial dynamics and morphology in beta-cells

Author keywords

beta cells; diabetes; fission; fusion; mitochondrial dynamics; mitochondrial morphology

Indexed keywords

CYTOCHROME C; INSULIN; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

EID: 84869431341     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2012.05.004     Document Type: Review
Times cited : (62)

References (65)
  • 1
    • 27744491193 scopus 로고    scopus 로고
    • Emerging functions of mammalian mitochondrial fusion and fission
    • H. Chen, and D.C. Chan Emerging functions of mammalian mitochondrial fusion and fission Human Molecular Genetics 14 Spec No. 2 2005 R283 R289
    • (2005) Human Molecular Genetics , vol.14 , Issue.SPEC. NO. 2
    • Chen, H.1    Chan, D.C.2
  • 2
    • 0028047262 scopus 로고
    • Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria
    • J. Bereiter-Hahn, and M. Voth Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria Microscopy Research and Techniques 27 1994 198 219
    • (1994) Microscopy Research and Techniques , vol.27 , pp. 198-219
    • Bereiter-Hahn, J.1    Voth, M.2
  • 3
    • 67650868959 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammalian health and disease
    • M. Liesa, M. Palacin, and A. Zorzano Mitochondrial dynamics in mammalian health and disease Physiological Reviews 89 2009 799 845
    • (2009) Physiological Reviews , vol.89 , pp. 799-845
    • Liesa, M.1    Palacin, M.2    Zorzano, A.3
  • 4
    • 0035057837 scopus 로고    scopus 로고
    • Control of mitochondrial morphology by a human mitofusin
    • A. Santel, and M.T. Fuller Control of mitochondrial morphology by a human mitofusin Journal of Cell Science 114 2001 867 874
    • (2001) Journal of Cell Science , vol.114 , pp. 867-874
    • Santel, A.1    Fuller, M.T.2
  • 5
    • 0037013266 scopus 로고    scopus 로고
    • Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology
    • T. Misaka, T. Miyashita, and Y. Kubo Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology Journal of Biological Chemistry 277 2002 15834 15842
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 15834-15842
    • Misaka, T.1    Miyashita, T.2    Kubo, Y.3
  • 6
    • 0141592470 scopus 로고    scopus 로고
    • HFis1, a novel component of the mammalian mitochondrial fission machinery
    • D.I. James, P.A. Parone, and Y. Mattenberger hFis1, a novel component of the mammalian mitochondrial fission machinery Journal of Biological Chemistry 278 2003 36373 36379
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 36373-36379
    • James, D.I.1    Parone, P.A.2    Mattenberger, Y.3
  • 7
    • 0742288598 scopus 로고    scopus 로고
    • The dynamin superfamily: Universal membrane tubulation and fission molecules?
    • G.J. Praefcke, and H.T. McMahon The dynamin superfamily: universal membrane tubulation and fission molecules? Nature Reviews. Molecular Cell Biology 5 2004 133 147
    • (2004) Nature Reviews. Molecular Cell Biology , vol.5 , pp. 133-147
    • Praefcke, G.J.1    McMahon, H.T.2
  • 8
    • 0043092647 scopus 로고    scopus 로고
    • The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
    • Y. Yoon, E.W. Krueger, and B.J. Oswald The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1 Molecular and Cellular Biology 23 2003 5409 5420
    • (2003) Molecular and Cellular Biology , vol.23 , pp. 5409-5420
    • Yoon, Y.1    Krueger, E.W.2    Oswald, B.J.3
  • 9
    • 44649129342 scopus 로고    scopus 로고
    • The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells
    • S. Gandre-Babbe, and A.M. van der Bliek The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells Molecular Biology of the Cell 19 2008 2402 2412
    • (2008) Molecular Biology of the Cell , vol.19 , pp. 2402-2412
    • Gandre-Babbe, S.1    Van Der Bliek, A.M.2
  • 10
    • 78650167618 scopus 로고    scopus 로고
    • Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
    • H. Otera, C. Wang, and M.M. Cleland Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells Journal of Cell Biology 191 2010 1141 1158
    • (2010) Journal of Cell Biology , vol.191 , pp. 1141-1158
    • Otera, H.1    Wang, C.2    Cleland, M.M.3
  • 11
    • 80054844842 scopus 로고    scopus 로고
    • ER tubules mark sites of mitochondrial division
    • J.R. Friedman, L.L. Lackner, and M. West ER tubules mark sites of mitochondrial division Science 334 2011 358 362
    • (2011) Science , vol.334 , pp. 358-362
    • Friedman, J.R.1    Lackner, L.L.2    West, M.3
  • 12
    • 0033600762 scopus 로고    scopus 로고
    • Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells
    • P. Maechler, L. Jornot, and C.B. Wollheim Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells Journal of Biological Chemistry 274 1999 27905 27913
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 27905-27913
    • Maechler, P.1    Jornot, L.2    Wollheim, C.B.3
  • 13
    • 57749185452 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in pancreatic beta-cells in Type 2 diabetes
    • H. Mulder, and C. Ling Mitochondrial dysfunction in pancreatic beta-cells in Type 2 diabetes Molecular and Cellular Endocrinology 297 2009 34 40
    • (2009) Molecular and Cellular Endocrinology , vol.297 , pp. 34-40
    • Mulder, H.1    Ling, C.2
  • 14
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • B.B. Lowell, and G.I. Shulman Mitochondrial dysfunction and type 2 diabetes Science 307 2005 384 387
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 15
    • 77449154126 scopus 로고    scopus 로고
    • Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes
    • H. Lu, V. Koshkin, and E.M. Allister Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes Diabetes 59 2010 448 459
    • (2010) Diabetes , vol.59 , pp. 448-459
    • Lu, H.1    Koshkin, V.2    Allister, E.M.3
  • 16
    • 0036865991 scopus 로고    scopus 로고
    • Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells
    • P. Maechler Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells Cellular and Molecular Life Science 59 2002 1803 1818
    • (2002) Cellular and Molecular Life Science , vol.59 , pp. 1803-1818
    • Maechler, P.1
  • 17
    • 84857785686 scopus 로고    scopus 로고
    • Mitochondrial signals drive insulin secretion in the pancreatic beta-cell
    • A. Wiederkehr, and C.B. Wollheim Mitochondrial signals drive insulin secretion in the pancreatic beta-cell Molecular and Cellular Endocrinology 353 2011 128 137
    • (2011) Molecular and Cellular Endocrinology , vol.353 , pp. 128-137
    • Wiederkehr, A.1    Wollheim, C.B.2
  • 18
    • 0031892856 scopus 로고    scopus 로고
    • Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells
    • E.D. Kennedy, P. Maechler, and C.B. Wollheim Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells Diabetes 47 1998 374 380
    • (1998) Diabetes , vol.47 , pp. 374-380
    • Kennedy, E.D.1    Maechler, P.2    Wollheim, C.B.3
  • 19
    • 34147110402 scopus 로고    scopus 로고
    • 2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: Comparison with glucose
    • 2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose Biochemical Journal 403 2007 197 205
    • (2007) Biochemical Journal , vol.403 , pp. 197-205
    • Heart, E.1    Yaney, G.C.2    Corkey, R.F.3
  • 20
    • 57749100271 scopus 로고    scopus 로고
    • Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells
    • K.S. Park, A. Wiederkehr, and C. Kirkpatrick Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells Journal of Biological Chemistry 283 2008 33347 33356
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 33347-33356
    • Park, K.S.1    Wiederkehr, A.2    Kirkpatrick, C.3
  • 21
    • 70349650451 scopus 로고    scopus 로고
    • Mitochondrial networking protects beta-cells from nutrient-induced apoptosis
    • A.J. Molina, J.D. Wikstrom, and L. Stiles Mitochondrial networking protects beta-cells from nutrient-induced apoptosis Diabetes 58 2009 2303 2315
    • (2009) Diabetes , vol.58 , pp. 2303-2315
    • Molina, A.J.1    Wikstrom, J.D.2    Stiles, L.3
  • 22
    • 65449184157 scopus 로고    scopus 로고
    • Monitoring mitochondrial dynamics with photoactivatable [corrected] green fluorescent protein
    • A.J. Molina, and O.S. Shirihai Monitoring mitochondrial dynamics with photoactivatable [corrected] green fluorescent protein Methods in Enzymology 457 2009 289 304
    • (2009) Methods in Enzymology , vol.457 , pp. 289-304
    • Molina, A.J.1    Shirihai, O.S.2
  • 23
    • 38549110110 scopus 로고    scopus 로고
    • Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
    • G. Twig, A. Elorza, and A.J. Molina Fission and selective fusion govern mitochondrial segregation and elimination by autophagy EMBO Journal 27 2008 433 446
    • (2008) EMBO Journal , vol.27 , pp. 433-446
    • Twig, G.1    Elorza, A.2    Molina, A.J.3
  • 24
    • 79958144429 scopus 로고    scopus 로고
    • Dynamin-related protein 1 is implicated in endoplasmic reticulum stress-induced pancreatic beta-cell apoptosis
    • L. Peng, X. Men, and W. Zhang Dynamin-related protein 1 is implicated in endoplasmic reticulum stress-induced pancreatic beta-cell apoptosis International Journal of Molecular Medicine 28 2011 161 169
    • (2011) International Journal of Molecular Medicine , vol.28 , pp. 161-169
    • Peng, L.1    Men, X.2    Zhang, W.3
  • 25
    • 59649130026 scopus 로고    scopus 로고
    • Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis
    • X. Men, H. Wang, and M. Li Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis International Journal of Biochemistry & Cell Biology 41 2009 879 890
    • (2009) International Journal of Biochemistry & Cell Biology , vol.41 , pp. 879-890
    • Men, X.1    Wang, H.2    Li, M.3
  • 26
    • 79959910616 scopus 로고    scopus 로고
    • The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells
    • Z. Zhang, N. Wakabayashi, and J. Wakabayashi The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells Molecular Biology of the Cell 22 2011 2235 2245
    • (2011) Molecular Biology of the Cell , vol.22 , pp. 2235-2245
    • Zhang, Z.1    Wakabayashi, N.2    Wakabayashi, J.3
  • 28
    • 61649085637 scopus 로고    scopus 로고
    • Macroautophagy in homeostasis of pancreatic beta-cell
    • H.S. Jung, and M.S. Lee Macroautophagy in homeostasis of pancreatic beta-cell Autophagy 5 2009 241 243
    • (2009) Autophagy , vol.5 , pp. 241-243
    • Jung, H.S.1    Lee, M.S.2
  • 29
    • 77953784925 scopus 로고    scopus 로고
    • Beta-cell autophagy: A novel mechanism regulating beta-cell function and mass: Lessons from beta-cell-specific Atg7-deficient mice
    • Y. Fujitani, C. Ebato, and T. Uchida Beta-cell autophagy: a novel mechanism regulating beta-cell function and mass: Lessons from beta-cell-specific Atg7-deficient mice Islets 1 2009 151 153
    • (2009) Islets , vol.1 , pp. 151-153
    • Fujitani, Y.1    Ebato, C.2    Uchida, T.3
  • 30
    • 52749094770 scopus 로고    scopus 로고
    • Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
    • H.S. Jung, K.W. Chung, and K.J. Won Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia Cell Metabolism 8 2008 318 324
    • (2008) Cell Metabolism , vol.8 , pp. 318-324
    • Jung, H.S.1    Chung, K.W.2    Won, K.J.3
  • 31
    • 52749093177 scopus 로고    scopus 로고
    • Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
    • C. Ebato, T. Uchida, and M. Arakawa Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet Cell Metabolism 8 2008 325 332
    • (2008) Cell Metabolism , vol.8 , pp. 325-332
    • Ebato, C.1    Uchida, T.2    Arakawa, M.3
  • 33
    • 43549108142 scopus 로고    scopus 로고
    • Glucolipotoxicity: Fuel excess and beta-cell dysfunction
    • V. Poitout, and R.P. Robertson Glucolipotoxicity: fuel excess and beta-cell dysfunction Endocrine Reviews 29 2008 351 366
    • (2008) Endocrine Reviews , vol.29 , pp. 351-366
    • Poitout, V.1    Robertson, R.P.2
  • 35
    • 33845934827 scopus 로고    scopus 로고
    • Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet
    • M. Fex, M.D. Nitert, and N. Wierup Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet Diabetologia 50 2007 74 83
    • (2007) Diabetologia , vol.50 , pp. 74-83
    • Fex, M.1    Nitert, M.D.2    Wierup, N.3
  • 36
    • 33947305767 scopus 로고    scopus 로고
    • Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose
    • G.S. Del, M. Grupillo, and M. Masini Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose Diabetes Metabolism Research and Review 23 2007 234 238
    • (2007) Diabetes Metabolism Research and Review , vol.23 , pp. 234-238
    • Del, G.S.1    Grupillo, M.2    Masini, M.3
  • 37
    • 0042922453 scopus 로고    scopus 로고
    • Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death
    • W. El-Assaad, J. Buteau, and M.L. Peyot Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death Endocrinology 144 2003 4154 4163
    • (2003) Endocrinology , vol.144 , pp. 4154-4163
    • El-Assaad, W.1    Buteau, J.2    Peyot, M.L.3
  • 38
    • 70449099192 scopus 로고    scopus 로고
    • Mitochondria mediated cell death in diabetes
    • G. Szabadkai, and M.R. Duchen Mitochondria mediated cell death in diabetes Apoptosis 14 2009 1405 1423
    • (2009) Apoptosis , vol.14 , pp. 1405-1423
    • Szabadkai, G.1    Duchen, M.R.2
  • 40
    • 0037984371 scopus 로고    scopus 로고
    • Visualizing superoxide production in normal and diabetic rat islets of Langerhans
    • V.P. Bindokas, A. Kuznetsov, and S. Sreenan Visualizing superoxide production in normal and diabetic rat islets of Langerhans Journal of Biological Chemistry 278 2003 9796 9801
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 9796-9801
    • Bindokas, V.P.1    Kuznetsov, A.2    Sreenan, S.3
  • 42
    • 77953809309 scopus 로고    scopus 로고
    • 4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes
    • A. Dlaskova, T. Spacek, and J. Santorova 4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes Biochimica et Biophysica Acta 1797 2010 1327 1341
    • (2010) Biochimica et Biophysica Acta , vol.1797 , pp. 1327-1341
    • Dlaskova, A.1    Spacek, T.2    Santorova, J.3
  • 43
    • 41049105265 scopus 로고    scopus 로고
    • Augmented beta cell loss and mitochondrial abnormalities in sucrose-fed GK rats
    • H. Mizukami, R. Wada, and M. Koyama Augmented beta cell loss and mitochondrial abnormalities in sucrose-fed GK rats Virchows Archiv 452 2008 383 392
    • (2008) Virchows Archiv , vol.452 , pp. 383-392
    • Mizukami, H.1    Wada, R.2    Koyama, M.3
  • 44
    • 0027345919 scopus 로고
    • Spontaneous diabetes mellitus in young cattle: Histologic, immunohistochemical, and electron microscopic studies of the islets of Langerhans
    • H. Taniyama, T. Shirakawa, and H. Furuoka Spontaneous diabetes mellitus in young cattle: histologic, immunohistochemical, and electron microscopic studies of the islets of Langerhans Veterinary Pathology 30 1993 46 54
    • (1993) Veterinary Pathology , vol.30 , pp. 46-54
    • Taniyama, H.1    Shirakawa, T.2    Furuoka, H.3
  • 45
    • 20244376316 scopus 로고    scopus 로고
    • Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients
    • M. Anello, R. Lupi, and D. Spampinato Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients Diabetologia 48 2005 282 289
    • (2005) Diabetologia , vol.48 , pp. 282-289
    • Anello, M.1    Lupi, R.2    Spampinato, D.3
  • 46
    • 34547958816 scopus 로고    scopus 로고
    • Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence
    • S. Lee, S.Y. Jeong, and W.C. Lim Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence Journal of Biological Chemistry 282 2007 22977 22983
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 22977-22983
    • Lee, S.1    Jeong, S.Y.2    Lim, W.C.3
  • 47
    • 33644552417 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
    • T. Yu, J.L. Robotham, and Y. Yoon Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology Proceedings of the National Academy of Sciences of the United States of America 103 2006 2653 2658
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , pp. 2653-2658
    • Yu, T.1    Robotham, J.L.2    Yoon, Y.3
  • 48
    • 34347399043 scopus 로고    scopus 로고
    • Reactive oxygen species as a signal in glucose-stimulated insulin secretion
    • J. Pi, Y. Bai, and Q. Zhang Reactive oxygen species as a signal in glucose-stimulated insulin secretion Diabetes 56 2007 1783 1791
    • (2007) Diabetes , vol.56 , pp. 1783-1791
    • Pi, J.1    Bai, Y.2    Zhang, Q.3
  • 50
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • O.M. de Brito, and L. Scorrano Mitofusin 2 tethers endoplasmic reticulum to mitochondria Nature 456 2008 605 610
    • (2008) Nature , vol.456 , pp. 605-610
    • De Brito, O.M.1    Scorrano, L.2
  • 51
    • 0041819756 scopus 로고    scopus 로고
    • Glutamate decreases mitochondrial size and movement in primary forebrain neurons
    • G.L. Rintoul, A.J. Filiano, and J.B. Brocard Glutamate decreases mitochondrial size and movement in primary forebrain neurons Journal of Neuroscience 23 2003 7881 7888
    • (2003) Journal of Neuroscience , vol.23 , pp. 7881-7888
    • Rintoul, G.L.1    Filiano, A.J.2    Brocard, J.B.3
  • 52
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • Z. Li, K. Okamoto, and Y. Hayashi The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses Cell 119 2004 873 887
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3
  • 54
    • 68649095201 scopus 로고    scopus 로고
    • Mitochondrial calcium and the permeability transition in cell death
    • J.J. Lemasters, T.P. Theruvath, and Z. Zhong Mitochondrial calcium and the permeability transition in cell death Biochimica et Biophysica Acta 1787 2009 1395 1401
    • (2009) Biochimica et Biophysica Acta , vol.1787 , pp. 1395-1401
    • Lemasters, J.J.1    Theruvath, T.P.2    Zhong, Z.3
  • 55
    • 0037593949 scopus 로고    scopus 로고
    • Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
    • D. Bach, S. Pich, and F.X. Soriano Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity Journal of Biological Chemistry 278 2003 17190 17197
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 17190-17197
    • Bach, D.1    Pich, S.2    Soriano, F.X.3
  • 56
    • 84856368290 scopus 로고    scopus 로고
    • Dynamic regulation of mitochondrial network and oxidative functions during 3T3-L1 fat cell differentiation
    • P.H. Ducluzeau, M. Priou, and M. Weitheimer Dynamic regulation of mitochondrial network and oxidative functions during 3T3-L1 fat cell differentiation Journal of Physiology and Biochemistry 67 2011 285 296
    • (2011) Journal of Physiology and Biochemistry , vol.67 , pp. 285-296
    • Ducluzeau, P.H.1    Priou, M.2    Weitheimer, M.3
  • 57
    • 38149130672 scopus 로고    scopus 로고
    • Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion
    • C. Affourtit, and M.D. Brand Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion Biochemical Journal 409 2008 199 204
    • (2008) Biochemical Journal , vol.409 , pp. 199-204
    • Affourtit, C.1    Brand, M.D.2
  • 58
    • 30044435536 scopus 로고    scopus 로고
    • Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria
    • C. Affourtit, and M.D. Brand Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria Biochemical Journal 393 2006 151 159
    • (2006) Biochemical Journal , vol.393 , pp. 151-159
    • Affourtit, C.1    Brand, M.D.2
  • 59
    • 46349101669 scopus 로고    scopus 로고
    • On the role of uncoupling protein-2 in pancreatic beta cells
    • C. Affourtit, and M.D. Brand On the role of uncoupling protein-2 in pancreatic beta cells Biochimica et Biophysica Acta 1777 2008 973 979
    • (2008) Biochimica et Biophysica Acta , vol.1777 , pp. 973-979
    • Affourtit, C.1    Brand, M.D.2
  • 60
    • 33845976357 scopus 로고    scopus 로고
    • Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology
    • S. Duvezin-Caubet, R. Jagasia, and J. Wagener Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology Journal of Biological Chemistry 281 2006 37972 37979
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 37972-37979
    • Duvezin-Caubet, S.1    Jagasia, R.2    Wagener, J.3
  • 61
    • 20444461625 scopus 로고    scopus 로고
    • The Charcot-Marie-tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
    • S. Pich, D. Bach, and P. Briones The Charcot-Marie-tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system Human Molecular Genetics 14 2005 1405 1415
    • (2005) Human Molecular Genetics , vol.14 , pp. 1405-1415
    • Pich, S.1    Bach, D.2    Briones, P.3
  • 62
    • 51749084230 scopus 로고    scopus 로고
    • Ultrastructure of the mitochondrion and its bearing on function and bioenergetics
    • G. Benard, and R. Rossignol Ultrastructure of the mitochondrion and its bearing on function and bioenergetics Antioxidants and Redox Signaling 10 2008 1313 1342
    • (2008) Antioxidants and Redox Signaling , vol.10 , pp. 1313-1342
    • Benard, G.1    Rossignol, R.2
  • 63
    • 34047173074 scopus 로고    scopus 로고
    • Mitochondrial bioenergetics and structural network organization
    • G. Benard, N. Bellance, and D. James Mitochondrial bioenergetics and structural network organization Journal of Cell Science 120 2007 838 848
    • (2007) Journal of Cell Science , vol.120 , pp. 838-848
    • Benard, G.1    Bellance, N.2    James, D.3
  • 64
    • 79954571354 scopus 로고    scopus 로고
    • The interplay between mitochondrial dynamics and mitophagy
    • G. Twig, and O.S. Shirihai The interplay between mitochondrial dynamics and mitophagy Antioxidants and Redox Signaling 14 2011 1939 1951
    • (2011) Antioxidants and Redox Signaling , vol.14 , pp. 1939-1951
    • Twig, G.1    Shirihai, O.S.2
  • 65
    • 81855189620 scopus 로고    scopus 로고
    • Organelle dynamics: ER embraces mitochondria for fission
    • B. Westermann Organelle dynamics: ER embraces mitochondria for fission Current Biology 21 2011 R922 R924
    • (2011) Current Biology , vol.21
    • Westermann, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.