A novel platform for automated high-throughput fluxome profiling of metabolic variants

Metabolic Engineering

Volumn 25, Issue , 2014, Pages 8-19

  Heux, Stéphanie ^a,b,c   Juliette, Poinot ^a,b,c   Stéphane, Massou ^a,b,c   Serguei, Sokol ^a,b,c   Jean Charles, Portais ^a,b,c  

^a INSA   (France)

^b UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

^c CNRS   (France)

Author keywords

Automation; Flux calculation; Fluxomics; High throughput; NMR; Statistical analysis

Indexed keywords

AUTOMATION; CELLS; CYTOLOGY; DATA PROCESSING; ESCHERICHIA COLI; NUCLEAR MAGNETIC RESONANCE; STATISTICAL METHODS;

FLUX CALCULATIONS; FLUXOMICS; GLUCOSE-6-PHOSPHATE DEHYDROGENASE; HIGH-THROUGHPUT; INTEGRATED SOLUTIONS; ISOTOPIC FINGERPRINTING; METABOLIC NETWORK; SCREENING CAPACITY;

METABOLISM;

CARBON 13; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; ESCHERICHIA COLI PROTEIN;

ARTICLE; AUTOMATION; BACTERIAL GROWTH; BACTERIAL STRAIN; CARBON SOURCE; CONTROLLED STUDY; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; ISOTOPE LABELING; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; ROBOTICS; STIRRED REACTOR; BATCH CELL CULTURE; DEVICE FAILURE ANALYSIS; DEVICES; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; GENETICS; METABOLIC FLUX ANALYSIS; METABOLOME; MUTATION; PEPTIDE MAPPING; PHYSIOLOGY; PROCEDURES; SYSTEM ANALYSIS;

BATCH CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION PROFILING; METABOLIC FLUX ANALYSIS; METABOLOME; MUTATION; PEPTIDE MAPPING; ROBOTICS; SYSTEMS INTEGRATION;

EID: 84903164690     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.06.001     Document Type: Article

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