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Volumn 56, Issue 5, 2014, Pages 335-348

Cdk5 regulates multiple cellular events in neural development, function and disease

Author keywords

Cell adhesion; Cyclin dependent kinase 5; Cytoskeleton; Neurodegenerative disease; Synapse

Indexed keywords

ACTIN; CYCLIN DEPENDENT KINASE 5;

EID: 84903144555     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/dgd.12138     Document Type: Article
Times cited : (86)

References (148)
  • 1
    • 34447130222 scopus 로고    scopus 로고
    • Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons
    • Anne, S. L., Saudou, F. & Humbert, S. 2007. Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons. J. Neurosci. 27, 7318-7328.
    • (2007) J. Neurosci. , vol.27 , pp. 7318-7328
    • Anne, S.L.1    Saudou, F.2    Humbert, S.3
  • 2
    • 48249132446 scopus 로고    scopus 로고
    • Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cyclin-dependent kinase 5 complexes
    • Asada, A., Yamamoto, N., Gohda, M., Saito, T., Hayashi, N. & Hisanaga, S. 2008. Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cyclin-dependent kinase 5 complexes. J. Neurochem. 106, 1325-1336.
    • (2008) J. Neurochem. , vol.106 , pp. 1325-1336
    • Asada, A.1    Yamamoto, N.2    Gohda, M.3    Saito, T.4    Hayashi, N.5    Hisanaga, S.6
  • 3
    • 0027757042 scopus 로고
    • Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
    • Baumann, K., Mandelkow, E. M., Biernat, J., Piwnica-Worms, H. & Mandelkow, E. 1993. Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5. FEBS Lett. 336, 417-424.
    • (1993) FEBS Lett. , vol.336 , pp. 417-424
    • Baumann, K.1    Mandelkow, E.M.2    Biernat, J.3    Piwnica-Worms, H.4    Mandelkow, E.5
  • 4
    • 1942466518 scopus 로고    scopus 로고
    • p27Kip1 modulates cell migration through the regulation of RhoA activation
    • Besson, A., Gurian-West, M., Schmidt, A., Hall, A. & Roberts, J. M. 2004. p27Kip1 modulates cell migration through the regulation of RhoA activation. Genes Dev. 18, 862-876.
    • (2004) Genes Dev. , vol.18 , pp. 862-876
    • Besson, A.1    Gurian-West, M.2    Schmidt, A.3    Hall, A.4    Roberts, J.M.5
  • 7
    • 35848935639 scopus 로고    scopus 로고
    • Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration
    • Causeret, F., Jacobs, T., Terao, M., Heath, O., Hoshino, M. & Nikolic, M. 2007. Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration. Mol. Biol. Cell 18, 4327-4342.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4327-4342
    • Causeret, F.1    Jacobs, T.2    Terao, M.3    Heath, O.4    Hoshino, M.5    Nikolic, M.6
  • 8
    • 0031018336 scopus 로고    scopus 로고
    • Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
    • Chae, T., Kwon, Y. T., Bronson, R., Dikkes, P., Li, E. & Tsai, L. H. 1997. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 18, 29-42.
    • (1997) Neuron , vol.18 , pp. 29-42
    • Chae, T.1    Kwon, Y.T.2    Bronson, R.3    Dikkes, P.4    Li, E.5    Tsai, L.H.6
  • 9
    • 1242274335 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
    • Chergui, K., Svenningsson, P. & Greengard, P. 2004. Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum. Proc. Natl Acad. Sci. USA 101, 2191-2196.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2191-2196
    • Chergui, K.1    Svenningsson, P.2    Greengard, P.3
  • 10
    • 84857781607 scopus 로고    scopus 로고
    • Cdk5: a multifaceted kinase in neurodegenerative diseases
    • Cheung, Z. H. & Ip, N. Y. 2012. Cdk5: a multifaceted kinase in neurodegenerative diseases. Trends Cell Biol. 22, 169-175.
    • (2012) Trends Cell Biol. , vol.22 , pp. 169-175
    • Cheung, Z.H.1    Ip, N.Y.2
  • 11
    • 27144478006 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation
    • Cicero, S. & Herrup, K. 2005. Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J. Neurosci. 25, 9658-9668.
    • (2005) J. Neurosci. , vol.25 , pp. 9658-9668
    • Cicero, S.1    Herrup, K.2
  • 13
    • 33846867244 scopus 로고    scopus 로고
    • Neurexin-neuroligin signaling in synapse development
    • Craig, A. M. & Kang, Y. 2007. Neurexin-neuroligin signaling in synapse development. Curr. Opin. Neurobiol. 17, 43-52.
    • (2007) Curr. Opin. Neurobiol. , vol.17 , pp. 43-52
    • Craig, A.M.1    Kang, Y.2
  • 14
    • 0345405447 scopus 로고    scopus 로고
    • Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
    • Cruz, J. C., Tseng, H. C., Goldman, J. A., Shih, H. & Tsai, L. H. 2003. Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron 40, 471-483.
    • (2003) Neuron , vol.40 , pp. 471-483
    • Cruz, J.C.1    Tseng, H.C.2    Goldman, J.A.3    Shih, H.4    Tsai, L.H.5
  • 16
    • 84882678652 scopus 로고    scopus 로고
    • Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex
    • Fang, W. Q., Chen, W. W., Fu, A. K. & Ip, N. Y. 2013. Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex. Neuron 79, 665-679.
    • (2013) Neuron , vol.79 , pp. 665-679
    • Fang, W.Q.1    Chen, W.W.2    Fu, A.K.3    Ip, N.Y.4
  • 17
    • 80053034084 scopus 로고    scopus 로고
    • Cdk5-mediated phosphorylation of Axin directs axon formation during cerebral cortex development
    • Fang, W. Q., Ip, J. P., Li, R., Ng, Y. P., Lin, S. C., Chen, Y., Fu, A. K. & Ip, N. Y. 2011. Cdk5-mediated phosphorylation of Axin directs axon formation during cerebral cortex development. J. Neurosci. 31, 13613-13624.
    • (2011) J. Neurosci. , vol.31 , pp. 13613-13624
    • Fang, W.Q.1    Ip, J.P.2    Li, R.3    Ng, Y.P.4    Lin, S.C.5    Chen, Y.6    Fu, A.K.7    Ip, N.Y.8
  • 19
    • 0035896503 scopus 로고    scopus 로고
    • Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2
    • Floyd, S. R., Porro, E. B., Slepnev, V. I., Ochoa, G. C., Tsai, L. H. & De Camilli, P. 2001. Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2. J. Biol. Chem. 276, 8104-8110.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8104-8110
    • Floyd, S.R.1    Porro, E.B.2    Slepnev, V.I.3    Ochoa, G.C.4    Tsai, L.H.5    De Camilli, P.6
  • 21
    • 0035088897 scopus 로고    scopus 로고
    • Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
    • Fu, A. K., Fu, W. Y., Cheung, J., Tsim, K. W., Ip, F. C., Wang, J. H. & Ip, N. Y. 2001. Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction. Nat. Neurosci. 4, 374-381.
    • (2001) Nat. Neurosci. , vol.4 , pp. 374-381
    • Fu, A.K.1    Fu, W.Y.2    Cheung, J.3    Tsim, K.W.4    Ip, F.C.5    Wang, J.H.6    Ip, N.Y.7
  • 24
    • 0032529699 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex
    • Gilmore, E. C., Ohshima, T., Goffinet, A. M., Kulkarni, A. B. & Herrup, K. 1998. Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex. J. Neurosci. 18, 6370-6377.
    • (1998) J. Neurosci. , vol.18 , pp. 6370-6377
    • Gilmore, E.C.1    Ohshima, T.2    Goffinet, A.M.3    Kulkarni, A.B.4    Herrup, K.5
  • 26
    • 0033152450 scopus 로고    scopus 로고
    • Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
    • Gleeson, J. G., Lin, P. T., Flanagan, L. A. & Walsh, C. A. 1999. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23, 257-271.
    • (1999) Neuron , vol.23 , pp. 257-271
    • Gleeson, J.G.1    Lin, P.T.2    Flanagan, L.A.3    Walsh, C.A.4
  • 28
    • 79955735275 scopus 로고    scopus 로고
    • The role of Rho GTPase proteins in CNS neuronal migration
    • Govek, E. E., Hatten, M. E. & Van Aelst, L. 2011. The role of Rho GTPase proteins in CNS neuronal migration. Dev. Neurobiol. 71, 528-553.
    • (2011) Dev. Neurobiol. , vol.71 , pp. 528-553
    • Govek, E.E.1    Hatten, M.E.2    Van Aelst, L.3
  • 29
    • 0029914941 scopus 로고    scopus 로고
    • CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins
    • Hata, Y., Butz, S. & Sudhof, T. C. 1996. CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins. J. Neurosci. 16, 2488-2494.
    • (1996) J. Neurosci. , vol.16 , pp. 2488-2494
    • Hata, Y.1    Butz, S.2    Sudhof, T.C.3
  • 30
    • 84860235192 scopus 로고    scopus 로고
    • Formation of axon-dendrite polarity in situ: initiation of axons from polarized and non-polarized cells
    • Hatanaka, Y., Yamauchi, K. & Murakami, F. 2012. Formation of axon-dendrite polarity in situ: initiation of axons from polarized and non-polarized cells. Dev. Growth Differ. 54, 398-407.
    • (2012) Dev. Growth Differ. , vol.54 , pp. 398-407
    • Hatanaka, Y.1    Yamauchi, K.2    Murakami, F.3
  • 32
    • 79958773486 scopus 로고    scopus 로고
    • The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein
    • He, L., Zhang, Z., Yu, Y., Ahmed, S., Cheung, N. S. & Qi, R. Z. 2011. The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein. Cell. Mol. Life Sci. 68, 1633-1643.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 1633-1643
    • He, L.1    Zhang, Z.2    Yu, Y.3    Ahmed, S.4    Cheung, N.S.5    Qi, R.Z.6
  • 33
    • 0026452774 scopus 로고
    • Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression
    • Hellmich, M. R., Pant, H. C., Wada, E. & Battey, J. F. 1992. Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression. Proc. Natl Acad. Sci. USA 89, 10867-10871.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 10867-10871
    • Hellmich, M.R.1    Pant, H.C.2    Wada, E.3    Battey, J.F.4
  • 34
    • 0027236625 scopus 로고
    • Tau protein kinase II has a similar characteristic to cdc2 kinase for phosphorylating neurofilament proteins
    • Hisanaga, S., Ishiguro, K., Uchida, T., Okumura, E., Okano, T. & Kishimoto, T. 1993. Tau protein kinase II has a similar characteristic to cdc2 kinase for phosphorylating neurofilament proteins. J. Biol. Chem. 268, 15056-15060.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15056-15060
    • Hisanaga, S.1    Ishiguro, K.2    Uchida, T.3    Okumura, E.4    Okano, T.5    Kishimoto, T.6
  • 35
    • 0025836712 scopus 로고
    • Phosphorylation of neurofilament H subunit at the tail domain by CDC2 kinase dissociates the association to microtubules
    • Hisanaga, S., Kusubata, M., Okumura, E. & Kishimoto, T. 1991. Phosphorylation of neurofilament H subunit at the tail domain by CDC2 kinase dissociates the association to microtubules. J. Biol. Chem. 266, 21798-21803.
    • (1991) J. Biol. Chem. , vol.266 , pp. 21798-21803
    • Hisanaga, S.1    Kusubata, M.2    Okumura, E.3    Kishimoto, T.4
  • 36
    • 84890884015 scopus 로고    scopus 로고
    • Tethering the assembly of SNARE complexes
    • Hong, W. & Lev, S. 2014. Tethering the assembly of SNARE complexes. Trends Cell Biol. 24, 35-43.
    • (2014) Trends Cell Biol. , vol.24 , pp. 35-43
    • Hong, W.1    Lev, S.2
  • 38
    • 84860240485 scopus 로고    scopus 로고
    • Neuronal subtype specification in the cerebellum and dorsal hindbrain
    • Hoshino, M. 2012. Neuronal subtype specification in the cerebellum and dorsal hindbrain. Dev. Growth Differ. 54, 317-326.
    • (2012) Dev. Growth Differ. , vol.54 , pp. 317-326
    • Hoshino, M.1
  • 39
    • 65449148205 scopus 로고    scopus 로고
    • Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration
    • Huang, C., Rajfur, Z., Yousefi, N., Chen, Z., Jacobson, K. & Ginsberg, M. H. 2009. Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration. Nat. Cell Biol. 11, 624-630.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 624-630
    • Huang, C.1    Rajfur, Z.2    Yousefi, N.3    Chen, Z.4    Jacobson, K.5    Ginsberg, M.H.6
  • 41
    • 0038030381 scopus 로고    scopus 로고
    • p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton
    • Humbert, S., Dhavan, R. & Tsai, L. 2000. p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton. J. Cell Sci. 113, 975-983.
    • (2000) J. Cell Sci. , vol.113 , pp. 975-983
    • Humbert, S.1    Dhavan, R.2    Tsai, L.3
  • 42
    • 0028207389 scopus 로고
    • Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain
    • Ishiguro, K., Kobayashi, S., Omori, A., Takamatsu, M., Yonekura, S., Anzai, K., Imahori, K. & Uchida, T. 1994. Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain. FEBS Lett. 342, 203-208.
    • (1994) FEBS Lett. , vol.342 , pp. 203-208
    • Ishiguro, K.1    Kobayashi, S.2    Omori, A.3    Takamatsu, M.4    Yonekura, S.5    Anzai, K.6    Imahori, K.7    Uchida, T.8
  • 45
    • 52049095054 scopus 로고    scopus 로고
    • Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability
    • Kaminosono, S., Saito, T., Oyama, F., Ohshima, T., Asada, A., Nagai, Y., Nukina, N. & Hisanaga, S. 2008. Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability. J. Neurosci. 28, 8747-8755.
    • (2008) J. Neurosci. , vol.28 , pp. 8747-8755
    • Kaminosono, S.1    Saito, T.2    Oyama, F.3    Ohshima, T.4    Asada, A.5    Nagai, Y.6    Nukina, N.7    Hisanaga, S.8
  • 46
    • 5644283146 scopus 로고    scopus 로고
    • Cellular and molecular control of dendritic growth and development of cerebellar Purkinje cells
    • Kapfhammer, J. P. 2004. Cellular and molecular control of dendritic growth and development of cerebellar Purkinje cells. Prog. Histochem. Cytochem. 39, 131-182.
    • (2004) Prog. Histochem. Cytochem. , vol.39 , pp. 131-182
    • Kapfhammer, J.P.1
  • 47
    • 84860180190 scopus 로고    scopus 로고
    • Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis
    • Kawauchi, T. 2012. Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis. Int. J. Mol. Sci. 13, 4564-4590.
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 4564-4590
    • Kawauchi, T.1
  • 48
    • 0042967835 scopus 로고    scopus 로고
    • The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
    • Kawauchi, T., Chihama, K., Nabeshima, Y. & Hoshino, M. 2003. The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J. 22, 4190-4201.
    • (2003) EMBO J. , vol.22 , pp. 4190-4201
    • Kawauchi, T.1    Chihama, K.2    Nabeshima, Y.3    Hoshino, M.4
  • 49
    • 30344457896 scopus 로고    scopus 로고
    • Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration
    • Kawauchi, T., Chihama, K., Nabeshima, Y. & Hoshino, M. 2006. Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration. Nat. Cell Biol. 8, 17-26.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 17-26
    • Kawauchi, T.1    Chihama, K.2    Nabeshima, Y.3    Hoshino, M.4
  • 51
    • 37149056530 scopus 로고    scopus 로고
    • Molecular pathways regulating cytoskeletal organization and morphological changes in migrating neurons
    • Kawauchi, T. & Hoshino, M. 2008. Molecular pathways regulating cytoskeletal organization and morphological changes in migrating neurons. Dev. Neurosci. 30, 36-46.
    • (2008) Dev. Neurosci. , vol.30 , pp. 36-46
    • Kawauchi, T.1    Hoshino, M.2
  • 52
    • 0034926171 scopus 로고    scopus 로고
    • Expression of vinexin [alpha] in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal
    • Kawauchi, T., Ikeya, M., Takada, S., Ueda, K., Shirai, M., Takihara, Y., Kioka, N. & Amachi, T. 2001. Expression of vinexin [alpha] in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal. Mech. Dev. 106, 147-150.
    • (2001) Mech. Dev. , vol.106 , pp. 147-150
    • Kawauchi, T.1    Ikeya, M.2    Takada, S.3    Ueda, K.4    Shirai, M.5    Takihara, Y.6    Kioka, N.7    Amachi, T.8
  • 53
    • 77955956961 scopus 로고    scopus 로고
    • Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking
    • Kawauchi, T., Sekine, K., Shikanai, M., Chihama, K., Tomita, K., Kubo, K., Nakajima, K., Nabeshima, Y. & Hoshino, M. 2010. Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking. Neuron 67, 588-602.
    • (2010) Neuron , vol.67 , pp. 588-602
    • Kawauchi, T.1    Sekine, K.2    Shikanai, M.3    Chihama, K.4    Tomita, K.5    Kubo, K.6    Nakajima, K.7    Nabeshima, Y.8    Hoshino, M.9
  • 54
    • 84874206003 scopus 로고    scopus 로고
    • Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders
    • Kawauchi, T., Shikanai, M. & Kosodo, Y. 2013. Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders. Genes Cells 18, 176-194.
    • (2013) Genes Cells , vol.18 , pp. 176-194
    • Kawauchi, T.1    Shikanai, M.2    Kosodo, Y.3
  • 57
    • 0037096334 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling
    • Keshvara, L., Magdaleno, S., Benhayon, D. & Curran, T. 2002. Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling. J. Neurosci. 22, 4869-4877.
    • (2002) J. Neurosci. , vol.22 , pp. 4869-4877
    • Keshvara, L.1    Magdaleno, S.2    Benhayon, D.3    Curran, T.4
  • 58
    • 59649114125 scopus 로고    scopus 로고
    • Synaptic AMPA receptor plasticity and behavior
    • Kessels, H. W. & Malinow, R. 2009. Synaptic AMPA receptor plasticity and behavior. Neuron 61, 340-350.
    • (2009) Neuron , vol.61 , pp. 340-350
    • Kessels, H.W.1    Malinow, R.2
  • 60
    • 77956314453 scopus 로고    scopus 로고
    • CDK5 serves as a major control point in neurotransmitter release
    • Kim, S. H. & Ryan, T. A. 2010. CDK5 serves as a major control point in neurotransmitter release. Neuron 67, 797-809.
    • (2010) Neuron , vol.67 , pp. 797-809
    • Kim, S.H.1    Ryan, T.A.2
  • 62
    • 0035448915 scopus 로고    scopus 로고
    • p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment
    • Ko, J., Humbert, S., Bronson, R. T., Takahashi, S., Kulkarni, A. B., Li, E. & Tsai, L. H. 2001. p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J. Neurosci. 21, 6758-6771.
    • (2001) J. Neurosci. , vol.21 , pp. 6758-6771
    • Ko, J.1    Humbert, S.2    Bronson, R.T.3    Takahashi, S.4    Kulkarni, A.B.5    Li, E.6    Tsai, L.H.7
  • 64
    • 0034595834 scopus 로고    scopus 로고
    • Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
    • Kusakawa, G., Saito, T., Onuki, R., Ishiguro, K., Kishimoto, T. & Hisanaga, S. 2000. Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J. Biol. Chem. 275, 17166-17172.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17166-17172
    • Kusakawa, G.1    Saito, T.2    Onuki, R.3    Ishiguro, K.4    Kishimoto, T.5    Hisanaga, S.6
  • 65
    • 0034611632 scopus 로고    scopus 로고
    • Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase
    • Kwon, Y. T., Gupta, A., Zhou, Y., Nikolic, M. & Tsai, L. H. 2000. Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase. Curr. Biol. 10, 363-372.
    • (2000) Curr. Biol. , vol.10 , pp. 363-372
    • Kwon, Y.T.1    Gupta, A.2    Zhou, Y.3    Nikolic, M.4    Tsai, L.H.5
  • 66
    • 0032527067 scopus 로고    scopus 로고
    • A novel disruption of cortical development in p35(-/-) mice distinct from reeler
    • Kwon, Y. T. & Tsai, L. H. 1998. A novel disruption of cortical development in p35(-/-) mice distinct from reeler. J. Comp. Neurol. 395, 510-522.
    • (1998) J. Comp. Neurol. , vol.395 , pp. 510-522
    • Kwon, Y.T.1    Tsai, L.H.2
  • 68
  • 69
  • 70
    • 0026680802 scopus 로고
    • Purification and characterization of a novel proline-directed protein kinase from bovine brain
    • Lew, J., Beaudette, K., Litwin, C. M. & Wang, J. H. 1992a. Purification and characterization of a novel proline-directed protein kinase from bovine brain. J. Biol. Chem. 267, 13383-13390.
    • (1992) J. Biol. Chem. , vol.267 , pp. 13383-13390
    • Lew, J.1    Beaudette, K.2    Litwin, C.M.3    Wang, J.H.4
  • 72
    • 0027087170 scopus 로고
    • Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2
    • Lew, J., Winkfein, R. J., Paudel, H. K. & Wang, J. H. 1992b. Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2. J. Biol. Chem. 267, 25922-25926.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25922-25926
    • Lew, J.1    Winkfein, R.J.2    Paudel, H.K.3    Wang, J.H.4
  • 74
    • 41149092840 scopus 로고    scopus 로고
    • CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5
    • Lin, S., Wang, J., Ye, Z., Ip, N. Y. & Lin, S. C. 2008. CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5. FEBS Lett. 582, 1197-1202.
    • (2008) FEBS Lett. , vol.582 , pp. 1197-1202
    • Lin, S.1    Wang, J.2    Ye, Z.3    Ip, N.Y.4    Lin, S.C.5
  • 75
    • 84896897470 scopus 로고    scopus 로고
    • Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration
    • Louvi, A., Nishimura, S. & Gunel, M. 2014. Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development 141, 1404-1415.
    • (2014) Development , vol.141 , pp. 1404-1415
    • Louvi, A.1    Nishimura, S.2    Gunel, M.3
  • 76
    • 22344439156 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity
    • Luo, S., Vacher, C., Davies, J. E. & Rubinsztein, D. C. 2005. Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity. J. Cell Biol. 169, 647-656.
    • (2005) J. Cell Biol. , vol.169 , pp. 647-656
    • Luo, S.1    Vacher, C.2    Davies, J.E.3    Rubinsztein, D.C.4
  • 79
    • 84868661907 scopus 로고    scopus 로고
    • A preferentially segregated recycling vesicle pool of limited size supports neurotransmission in native central synapses
    • Marra, V., Burden, J. J., Thorpe, J. R., Smith, I. T., Smith, S. L., Hausser, M., Branco, T. & Staras, K. 2012. A preferentially segregated recycling vesicle pool of limited size supports neurotransmission in native central synapses. Neuron 76, 579-589.
    • (2012) Neuron , vol.76 , pp. 579-589
    • Marra, V.1    Burden, J.J.2    Thorpe, J.R.3    Smith, I.T.4    Smith, S.L.5    Hausser, M.6    Branco, T.7    Staras, K.8
  • 81
    • 77956464559 scopus 로고    scopus 로고
    • Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum
    • Miyata, T., Ono, Y., Okamoto, M., Masaoka, M., Sakakibara, A., Kawaguchi, A., Hashimoto, M. & Ogawa, M. 2010. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 5, 23.
    • (2010) Neural Dev. , vol.5 , pp. 23
    • Miyata, T.1    Ono, Y.2    Okamoto, M.3    Masaoka, M.4    Sakakibara, A.5    Kawaguchi, A.6    Hashimoto, M.7    Ogawa, M.8
  • 82
    • 84870557707 scopus 로고    scopus 로고
    • Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation
    • Mizuno, K. 2013. Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation. Cell. Signal. 25, 457-469.
    • (2013) Cell. Signal. , vol.25 , pp. 457-469
    • Mizuno, K.1
  • 83
    • 0742270492 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons
    • Morabito, M. A., Sheng, M. & Tsai, L. H. 2004. Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. J. Neurosci. 24, 865-876.
    • (2004) J. Neurosci. , vol.24 , pp. 865-876
    • Morabito, M.A.1    Sheng, M.2    Tsai, L.H.3
  • 85
    • 0037092515 scopus 로고    scopus 로고
    • Cdk5 regulates cell-matrix and cell-cell adhesion in lens epithelial cells
    • Negash, S., Wang, H. S., Gao, C., Ledee, D. & Zelenka, P. 2002. Cdk5 regulates cell-matrix and cell-cell adhesion in lens epithelial cells. J. Cell Sci. 115, 2109-2117.
    • (2002) J. Cell Sci. , vol.115 , pp. 2109-2117
    • Negash, S.1    Wang, H.S.2    Gao, C.3    Ledee, D.4    Zelenka, P.5
  • 87
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions
    • Nguyen, M. D., Lariviere, R. C. & Julien, J. P. 2001. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30, 135-147.
    • (2001) Neuron , vol.30 , pp. 135-147
    • Nguyen, M.D.1    Lariviere, R.C.2    Julien, J.P.3
  • 88
  • 89
    • 0029966469 scopus 로고    scopus 로고
    • The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
    • Nikolic, M., Dudek, H., Kwon, Y. T., Ramos, Y. F. & Tsai, L. H. 1996. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10, 816-825.
    • (1996) Genes Dev. , vol.10 , pp. 816-825
    • Nikolic, M.1    Dudek, H.2    Kwon, Y.T.3    Ramos, Y.F.4    Tsai, L.H.5
  • 90
    • 77949311926 scopus 로고    scopus 로고
    • Dissecting the factors involved in the locomotion mode of neuronal migration in the developing cerebral cortex
    • Nishimura, Y. V., Sekine, K., Chihama, K., Nakajima, K., Hoshino, M., Nabeshima, Y. & Kawauchi, T. 2010. Dissecting the factors involved in the locomotion mode of neuronal migration in the developing cerebral cortex. J. Biol. Chem. 285, 5878-5887.
    • (2010) J. Biol. Chem. , vol.285 , pp. 5878-5887
    • Nishimura, Y.V.1    Sekine, K.2    Chihama, K.3    Nakajima, K.4    Hoshino, M.5    Nabeshima, Y.6    Kawauchi, T.7
  • 97
    • 32544442688 scopus 로고    scopus 로고
    • Impaired neuronal positioning and dendritogenesis in the neocortex after cell-autonomous Dab1 suppression
    • Olson, E. C., Kim, S. & Walsh, C. A. 2006. Impaired neuronal positioning and dendritogenesis in the neocortex after cell-autonomous Dab1 suppression. J. Neurosci. 26, 1767-1775.
    • (2006) J. Neurosci. , vol.26 , pp. 1767-1775
    • Olson, E.C.1    Kim, S.2    Walsh, C.A.3
  • 98
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    • Patrick, G. N., Zukerberg, L., Nikolic, M., De La Monte, S., Dikkes, P. & Tsai, L. H. 1999. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402, 615-622.
    • (1999) Nature , vol.402 , pp. 615-622
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3    De La Monte, S.4    Dikkes, P.5    Tsai, L.H.6
  • 99
    • 0034773788 scopus 로고    scopus 로고
    • Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase
    • Patterson, S. L., Pittenger, C., Morozov, A., Martin, K. C., Scanlin, H., Drake, C. & Kandel, E. R. 2001. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron 32, 123-140.
    • (2001) Neuron , vol.32 , pp. 123-140
    • Patterson, S.L.1    Pittenger, C.2    Morozov, A.3    Martin, K.C.4    Scanlin, H.5    Drake, C.6    Kandel, E.R.7
  • 102
    • 33748752882 scopus 로고    scopus 로고
    • The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation
    • Plattner, F., Angelo, M. & Giese, K. P. 2006. The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation. J. Biol. Chem. 281, 25457-25465.
    • (2006) J. Biol. Chem. , vol.281 , pp. 25457-25465
    • Plattner, F.1    Angelo, M.2    Giese, K.P.3
  • 104
    • 67651114067 scopus 로고    scopus 로고
    • Cortical interneurons require p35/Cdk5 for their migration and laminar organization
    • Rakic, S., Yanagawa, Y., Obata, K., Faux, C., Parnavelas, J. G. & Nikolic, M. 2009. Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Cereb. Cortex 19, 1857-1869.
    • (2009) Cereb. Cortex , vol.19 , pp. 1857-1869
    • Rakic, S.1    Yanagawa, Y.2    Obata, K.3    Faux, C.4    Parnavelas, J.G.5    Nikolic, M.6
  • 106
    • 33947303519 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus
    • Rex, C. S., Lin, C. Y., Kramar, E. A., Chen, L. Y., Gall, C. M. & Lynch, G. 2007. Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus. J. Neurosci. 27, 3017-3029.
    • (2007) J. Neurosci. , vol.27 , pp. 3017-3029
    • Rex, C.S.1    Lin, C.Y.2    Kramar, E.A.3    Chen, L.Y.4    Gall, C.M.5    Lynch, G.6
  • 107
    • 79551477143 scopus 로고    scopus 로고
    • Cerebellum development and medulloblastoma
    • Roussel, M. F. & Hatten, M. E. 2011. Cerebellum development and medulloblastoma. Curr. Top. Dev. Biol. 94, 235-282.
    • (2011) Curr. Top. Dev. Biol. , vol.94 , pp. 235-282
    • Roussel, M.F.1    Hatten, M.E.2
  • 112
    • 79959675087 scopus 로고    scopus 로고
    • The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the Dab1-dependent "inside-out" lamination in the neocortex
    • Sekine, K., Honda, T., Kawauchi, T., Kubo, K. & Nakajima, K. 2011. The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the Dab1-dependent "inside-out" lamination in the neocortex. J. Neurosci. 31, 9426-9439.
    • (2011) J. Neurosci. , vol.31 , pp. 9426-9439
    • Sekine, K.1    Honda, T.2    Kawauchi, T.3    Kubo, K.4    Nakajima, K.5
  • 113
    • 84867730037 scopus 로고    scopus 로고
    • Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin alpha5beta1
    • Sekine, K., Kawauchi, T., Kubo, K., Honda, T., Herz, J., Hattori, M., Kinashi, T. & Nakajima, K. 2012. Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin alpha5beta1. Neuron 76, 353-369.
    • (2012) Neuron , vol.76 , pp. 353-369
    • Sekine, K.1    Kawauchi, T.2    Kubo, K.3    Honda, T.4    Herz, J.5    Hattori, M.6    Kinashi, T.7    Nakajima, K.8
  • 115
    • 84860154681 scopus 로고    scopus 로고
    • N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons
    • Shikanai, M., Nakajima, K. & Kawauchi, T. 2011. N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons. Commun. Integr. Biol. 4, 326-330.
    • (2011) Commun. Integr. Biol. , vol.4 , pp. 326-330
    • Shikanai, M.1    Nakajima, K.2    Kawauchi, T.3
  • 116
    • 84871649258 scopus 로고    scopus 로고
    • Deregulated Cdk5 activity is involved in inducing Alzheimer's disease
    • Shukla, V., Skuntz, S. & Pant, H. C. 2012. Deregulated Cdk5 activity is involved in inducing Alzheimer's disease. Arch. Med. Res. 43, 655-662.
    • (2012) Arch. Med. Res. , vol.43 , pp. 655-662
    • Shukla, V.1    Skuntz, S.2    Pant, H.C.3
  • 117
    • 77954504217 scopus 로고    scopus 로고
    • Dixdc1 is a critical regulator of DISC1 and embryonic cortical development
    • Singh, K. K., Ge, X., Mao, Y., Drane, L., Meletis, K., Samuels, B. A. & Tsai, L. H. 2010. Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron 67, 33-48.
    • (2010) Neuron , vol.67 , pp. 33-48
    • Singh, K.K.1    Ge, X.2    Mao, Y.3    Drane, L.4    Meletis, K.5    Samuels, B.A.6    Tsai, L.H.7
  • 119
    • 84884142238 scopus 로고    scopus 로고
    • Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment
    • Su, S. C., Rudenko, A., Cho, S. & Tsai, L. H. 2013. Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment. Neurobiol. Learn. Mem. 105, 54-62.
    • (2013) Neurobiol. Learn. Mem. , vol.105 , pp. 54-62
    • Su, S.C.1    Rudenko, A.2    Cho, S.3    Tsai, L.H.4
  • 120
    • 84865363824 scopus 로고    scopus 로고
    • Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5
    • Su, S. C., Seo, J., Pan, J. Q., Samuels, B. A., Rudenko, A., Ericsson, M., Neve, R. L., Yue, D. T. & Tsai, L. H. 2012. Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5. Neuron 75, 675-687.
    • (2012) Neuron , vol.75 , pp. 675-687
    • Su, S.C.1    Seo, J.2    Pan, J.Q.3    Samuels, B.A.4    Rudenko, A.5    Ericsson, M.6    Neve, R.L.7    Yue, D.T.8    Tsai, L.H.9
  • 124
    • 1642452714 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration
    • Tanaka, T., Serneo, F. F., Tseng, H. C., Kulkarni, A. B., Tsai, L. H. & Gleeson, J. G. 2004. Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration. Neuron 41, 215-227.
    • (2004) Neuron , vol.41 , pp. 215-227
    • Tanaka, T.1    Serneo, F.F.2    Tseng, H.C.3    Kulkarni, A.B.4    Tsai, L.H.5    Gleeson, J.G.6
  • 126
    • 59649128916 scopus 로고    scopus 로고
    • Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death
    • Tian, B., Yang, Q. & Mao, Z. 2009. Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death. Nat. Cell Biol. 11, 211-218.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 211-218
    • Tian, B.1    Yang, Q.2    Mao, Z.3
  • 129
    • 34547533825 scopus 로고    scopus 로고
    • Dual subcellular roles for LIS1 and dynein in radial neuronal migration in live brain tissue
    • Tsai, J. W., Bremner, K. H. & Vallee, R. B. 2007. Dual subcellular roles for LIS1 and dynein in radial neuronal migration in live brain tissue. Nat. Neurosci. 10, 970-979.
    • (2007) Nat. Neurosci. , vol.10 , pp. 970-979
    • Tsai, J.W.1    Bremner, K.H.2    Vallee, R.B.3
  • 130
    • 0027978170 scopus 로고
    • p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
    • Tsai, L. H., Delalle, I., Caviness, V. S. Jr., Chae, T. & Harlow, E. 1994. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature 371, 419-423.
    • (1994) Nature , vol.371 , pp. 419-423
    • Tsai, L.H.1    Delalle, I.2    Caviness Jr, V.S.3    Chae, T.4    Harlow, E.5
  • 131
    • 18144364317 scopus 로고    scopus 로고
    • Nucleokinesis in neuronal migration
    • Tsai, L. H. & Gleeson, J. G. 2005. Nucleokinesis in neuronal migration. Neuron 46, 383-388.
    • (2005) Neuron , vol.46 , pp. 383-388
    • Tsai, L.H.1    Gleeson, J.G.2
  • 132
    • 0027425599 scopus 로고
    • Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
    • Tsai, L. H., Takahashi, T., Caviness, V. S. Jr. & Harlow, E. 1993. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development 119, 1029-1040.
    • (1993) Development , vol.119 , pp. 1029-1040
    • Tsai, L.H.1    Takahashi, T.2    Caviness Jr, V.S.3    Harlow, E.4
  • 133
    • 0027971397 scopus 로고
    • Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain
    • Uchida, T., Ishiguro, K., Ohnuma, J., Takamatsu, M., Yonekura, S. & Imahori, K. 1994. Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain. FEBS Lett. 355, 35-40.
    • (1994) FEBS Lett. , vol.355 , pp. 35-40
    • Uchida, T.1    Ishiguro, K.2    Ohnuma, J.3    Takamatsu, M.4    Yonekura, S.5    Imahori, K.6
  • 134
    • 84870373458 scopus 로고    scopus 로고
    • Differential roles of cyclin-dependent kinase 5 in tangential and radial migration of cerebellar granule cells
    • Umeshima, H. & Kengaku, M. 2013. Differential roles of cyclin-dependent kinase 5 in tangential and radial migration of cerebellar granule cells. Mol. Cell. Neurosci. 52, 62-72.
    • (2013) Mol. Cell. Neurosci. , vol.52 , pp. 62-72
    • Umeshima, H.1    Kengaku, M.2
  • 135
    • 0141542665 scopus 로고    scopus 로고
    • Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
    • Wang, J., Liu, S., Fu, Y., Wang, J. H. & Lu, Y. 2003. Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. Nat. Neurosci. 6, 1039-1047.
    • (2003) Nat. Neurosci. , vol.6 , pp. 1039-1047
    • Wang, J.1    Liu, S.2    Fu, Y.3    Wang, J.H.4    Lu, Y.5
  • 137
    • 40449087334 scopus 로고    scopus 로고
    • Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing
    • Wen, Y., Planel, E., Herman, M., Figueroa, H. Y., Wang, L., Liu, L., Lau, L. F., Yu, W. H. & Duff, K. E. 2008. Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing. J. Neurosci. 28, 2624-2632.
    • (2008) J. Neurosci. , vol.28 , pp. 2624-2632
    • Wen, Y.1    Planel, E.2    Herman, M.3    Figueroa, H.Y.4    Wang, L.5    Liu, L.6    Lau, L.F.7    Yu, W.H.8    Duff, K.E.9
  • 138
    • 84884189701 scopus 로고    scopus 로고
    • Drebrin contains a cryptic F-actin-bundling activity regulated by Cdk5 phosphorylation
    • Worth, D. C., Daly, C. N., Geraldo, S., Oozeer, F. & Gordon-Weeks, P. R. 2013. Drebrin contains a cryptic F-actin-bundling activity regulated by Cdk5 phosphorylation. J. Cell Biol. 202, 793-806.
    • (2013) J. Cell Biol. , vol.202 , pp. 793-806
    • Worth, D.C.1    Daly, C.N.2    Geraldo, S.3    Oozeer, F.4    Gordon-Weeks, P.R.5
  • 139
    • 0042329506 scopus 로고    scopus 로고
    • Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
    • Xie, Z., Sanada, K., Samuels, B. A., Shih, H. & Tsai, L. H. 2003. Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell 114, 469-482.
    • (2003) Cell , vol.114 , pp. 469-482
    • Xie, Z.1    Sanada, K.2    Samuels, B.A.3    Shih, H.4    Tsai, L.H.5
  • 140
    • 0026459047 scopus 로고
    • D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
    • Xiong, Y., Zhang, H. & Beach, D. 1992. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71, 505-514.
    • (1992) Cell , vol.71 , pp. 505-514
    • Xiong, Y.1    Zhang, H.2    Beach, D.3
  • 142
    • 79952003369 scopus 로고    scopus 로고
    • Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse
    • Yang, J., Dominguez, B., De Winter, F., Gould, T. W., Eriksson, J. E. & Lee, K. F. 2011. Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse. Nat. Neurosci. 14, 324-330.
    • (2011) Nat. Neurosci. , vol.14 , pp. 324-330
    • Yang, J.1    Dominguez, B.2    De Winter, F.3    Gould, T.W.4    Eriksson, J.E.5    Lee, K.F.6
  • 143
    • 33947289969 scopus 로고    scopus 로고
    • Cell division in the CNS: protective response or lethal event in post-mitotic neurons?
    • Yang, Y. & Herrup, K. 2007. Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim. Biophys. Acta 1772, 457-466.
    • (2007) Biochim. Biophys. Acta , vol.1772 , pp. 457-466
    • Yang, Y.1    Herrup, K.2
  • 144
    • 79955650804 scopus 로고    scopus 로고
    • Cbln1 and its family proteins in synapse formation and maintenance
    • Yuzaki, M. 2011. Cbln1 and its family proteins in synapse formation and maintenance. Curr. Opin. Neurobiol. 21, 215-220.
    • (2011) Curr. Opin. Neurobiol. , vol.21 , pp. 215-220
    • Yuzaki, M.1
  • 145
    • 77950962922 scopus 로고    scopus 로고
    • Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex
    • Zhang, J., Li, H., Yabut, O., Fitzpatrick, H., D'arcangelo, G. & Herrup, K. 2010a. Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J. Neurosci. 30, 5219-5228.
    • (2010) J. Neurosci. , vol.30 , pp. 5219-5228
    • Zhang, J.1    Li, H.2    Yabut, O.3    Fitzpatrick, H.4    D'arcangelo, G.5    Herrup, K.6
  • 146
    • 78049351867 scopus 로고    scopus 로고
    • S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development
    • Zhang, P., Yu, P. C., Tsang, A. H., Chen, Y., Fu, A. K., Fu, W. Y., Chung, K. K. & Ip, N. Y. 2010b. S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development. J. Neurosci. 30, 14366-14370.
    • (2010) J. Neurosci. , vol.30 , pp. 14366-14370
    • Zhang, P.1    Yu, P.C.2    Tsang, A.H.3    Chen, Y.4    Fu, A.K.5    Fu, W.Y.6    Chung, K.K.7    Ip, N.Y.8
  • 147
    • 38349009068 scopus 로고    scopus 로고
    • Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors
    • Zhang, S., Edelmann, L., Liu, J., Crandall, J. E. & Morabito, M. A. 2008. Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors. J. Neurosci. 28, 415-424.
    • (2008) J. Neurosci. , vol.28 , pp. 415-424
    • Zhang, S.1    Edelmann, L.2    Liu, J.3    Crandall, J.E.4    Morabito, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.