New Insights into Vinculin Function and Regulation

International Review of Cell and Molecular Biology

Volumn 287, Issue , 2011, Pages 191-231

  Peng, Xiao ^a   Nelson, Elke S ^a   Maiers, Jessica L ^a   DeMali, Kris A ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cadherins; Cell adhesion; Cell migration and Actin; Force generation; Integrins; Vinculin

Indexed keywords

CADHERIN; PROLINE; TYROSINE; VINCULIN;

APOPTOSIS; BOOK; CARDIOMYOPATHY; CELL ADHESION; CELL MIGRATION; CONFORMATIONAL TRANSITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; REGULATORY MECHANISM;

SHIGELLA;

EID: 79952603041     PISSN: 19376448     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-386043-9.00005-0     Document Type: Chapter

References (179)

1. Adey N.B., Kay B.K. Isolation of peptides from phage-displayed random peptide libraries that interact with the talin-binding domain of vinculin. Biochem. J. 1997, 324(Pt. 2):523-528.
2. Alenghat F.J., Fabry B., Tsai K.Y., Goldmann W.H., Ingber D.E. Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer. Biochem. Biophys. Res. Commun. 2000, 277:93-99.
3. Auweter S.D., Allain F.H. Structure-function relationships of the polypyrimidine tract binding protein. Cell. Mol. Life Sci. 2008, 65:516-527.
4. Ayalon O., Geiger B. Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells. J. Cell Sci. 1997, 110(Pt. 5):547-556.
5. Babic I., Sharma S., Black D.L. A role for polypyrimidine tract binding protein in the establishment of focal adhesions. Mol. Cell. Biol. 2009, 29:5564-5577.
6. Bakolitsa C., de Pereda J.M., Bagshaw C.R., Critchley D.R., Liddington R.C. Crystal structure of the vinculin tail suggests a pathway for activation. Cell 1999, 99:603-613.
7. Bakolitsa C., Cohen D.M., Bankston L.A., Bobkov A.A., Cadwell G.W., Jennings L., et al. Structural basis for vinculin activation at sites of cell adhesion. Nature 2004, 430:583-586.
8. Bass M.D., Patel B., Barsukov I.G., Fillingham I.J., Mason R., Smith B.J., et al. Further characterization of the interaction between the cytoskeletal proteins talin and vinculin. Biochem. J. 2002, 362:761-768.
9. Berrier A.L., Yamada K.M. Cell-matrix adhesion. J. Cell. Physiol. 2007, 213:565-573.
10. Bloch R.J., Hall Z.W. Cytoskeletal components of the vertebrate neuromuscular junction: vinculin, alpha-actinin, and filamin. J. Cell Biol. 1983, 97:217-223.
11. Bois P.R., Borgon R.A., Vonrhein C., Izard T. Structural dynamics of alpha-actinin-vinculin interactions. Mol. Cell. Biol. 2005, 25:6112-6122.
12. Bois P.R., O'Hara B.P., Nietlispach D., Kirkpatrick J., Izard T. The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin. J. Biol. Chem. 2006, 281:7228-7236.
13. Borgon R.A., Vonrhein C., Bricogne G., Bois P.R., Izard T. Crystal structure of human vinculin. Structure 2004, 12:1189-1197.
14. Bourdet-Sicard R., Rudiger M., Jockusch B.M., Gounon P., Sansonetti P.J., Nhieu G.T. Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization. EMBO J. 1999, 18:5853-5862.
15. Brindle N.P., Holt M.R., Davies J.E., Price C.J., Critchley D.R. The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin. Biochem. J. 1996, 318(Pt. 3):753-757.
16. Burridge K., Feramisco J.R. Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectin. Cell 1980, 19:587-595.
17. Burridge K., Mangeat P. An interaction between vinculin and talin. Nature 1984, 308:744-746.
18. Calderwood D.A., Zent R., Grant R., Rees D.J., Hynes R.O., Ginsberg M.H. The talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J. Biol. Chem. 1999, 274:28071-28074.
19. Carisey A., Ballestrem C. Vinculin, an adapter protein in control of cell adhesion signalling. Eur. J. Cell Biol. 2010, 90, 157-163.
20. Castano J., Raurell I., Piedra J.A., Miravet S., Dunach M., Garcia de Herreros A. Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin. J. Biol. Chem. 2002, 277:31541-31550.
21. Ceccarelli D.F., Song H.K., Poy F., Schaller M.D., Eck M.J. Crystal structure of the FERM domain of focal adhesion kinase. J. Biol. Chem. 2006, 281:252-259.
22. Chandrasekar I., Stradal T.E., Holt M.R., Entschladen F., Jockusch B.M., Ziegler W.H. Vinculin acts as a sensor in lipid regulation of adhesion-site turnover. J. Cell Sci. 2005, 118:1461-1472.
23. Chen H., Cohen D.M., Choudhury D.M., Kioka N., Craig S.W. Spatial distribution and functional significance of activated vinculin in living cells. J. Cell Biol. 2005, 169:459-470.
24. Chen H., Choudhury D.M., Craig S.W. Coincidence of actin filaments and talin is required to activate vinculin. J. Biol. Chem. 2006, 281:40389-40398.
25. Cohen D.M., Chen H., Johnson R.P., Choudhury B., Craig S.W. Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin. J. Biol. Chem. 2005, 280:17109-17117.
26. Cohen D.M., Kutscher B., Chen H., Murphy D.B., Craig S.W. A conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions. J. Biol. Chem. 2006, 281:16006-16015.
27. Coll J.L., Ben-Ze'ev A., Ezzell R.M., Rodriguez Fernandez J.L., Baribault H., Oshima R.G., et al. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc. Natl. Acad. Sci. USA 1995, 92:9161-9165.
28. Coutu M.D., Craig S.W. cDNA-derived sequence of chicken embryo vinculin. Proc. Natl. Acad. Sci. USA 1988, 85:8535-8539.
29. del Rio A., Perez-Jimenez R., Liu R., Roca-Cusachs P., Fernandez J.M., Sheetz M.P. Stretching single talin rod molecules activates vinculin binding. Science 2009, 323:638-641.
30. DeMali K.A., Burridge K. Coupling membrane protrusion and cell adhesion. J. Cell Sci. 2003, 116:2389-2397.
31. DeMali K.A., Barlow C.A., Burridge K. Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion. J. Cell Biol. 2002, 159:881-891.
32. DeMali K.A., Jue A.L., Burridge K. IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry. J. Biol. Chem. 2006, 281:39534-39541.
33. Diez G., Kollmannsberger P., Mierke C.T., Koch T.M., Vali H., Fabry B., et al. Anchorage of vinculin to lipid membranes influences cell mechanical properties. Biophys. J. 2009, 97:3105-3112.
34. Drenckhahn D., Franz H. Identification of actin-, alpha-actinin-, and vinculin-containing plaques at the lateral membrane of epithelial cells. J. Cell Biol. 1986, 102:1843-1852.
35. Drenckhahn D., Mannherz H.G. Distribution of actin and the actin-associated proteins myosin, tropomyosin, alpha-actinin, vinculin, and villin in rat and bovine exocrine glands. Eur. J. Cell Biol. 1983, 30:167-176.
36. Eimer W., Niermann M., Eppe M.A., Jockusch B.M. Molecular shape of vinculin in aqueous solution. J. Mol. Biol. 1993, 229:146-152.
37. Fillingham I., Gingras A.R., Papagrigoriou E., Patel B., Emsley J., Critchley D.R., et al. A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head. Structure 2005, 13:65-74.
38. Finlay B.B., Ruschkowski S., Dedhar S. Cytoskeletal rearrangements accompanying salmonella entry into epithelial cells. J. Cell Sci. 1991, 99(Pt. 2):283-296.
39. Finlay B.B., Rosenshine I., Donnenberg M.S., Kaper J.B. Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells. Infect. Immun. 1992, 60:2541-2543.
40. Galbraith C.G., Yamada K.M., Sheetz M.P. The relationship between force and focal complex development. J. Cell Biol. 2002, 159:695-705.
41. Gallant N.D., Michael K.E., Garcia A.J. Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly. Mol. Biol. Cell 2005, 16:4329-4340.
42. Garcia-Alvarez B., de Pereda J.M., Calderwood D.A., Ulmer T.S., Critchley D., Campbell I.D., et al. Structural determinants of integrin recognition by talin. Mol. Cell 2003, 11:49-58.
43. Geiger B. A 130 K protein from chicken gizzard: its localization at the termini of microfilament bundles in cultured chicken cells. Cell 1979, 18:193-205.
44. Geiger B., Tokuyasu K.T., Dutton A.H., Singer S.J. Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes. Proc. Natl. Acad. Sci. USA 1980, 77:4127-4131.
45. Geiger B., Dutton A.H., Tokuyasu K.T., Singer S.J. Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells. J. Cell Biol. 1981, 91:614-628.
46. Geiger B., Volk T., Volberg T. Molecular heterogeneity of adherens junctions. J. Cell Biol. 1985, 101:1523-1531.
47. Gilmore A.P., Burridge K. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate. Nature 1996, 381:531-535.
48. Gingras A.R., Ziegler W.H., Frank R., Barsukov I.L., Roberts G.C., Critchley D.R., et al. Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. J. Biol. Chem. 2005, 280:37217-37224.
49. Gingras A.R., Vogel K.P., Steinhoff H.J., Ziegler W.H., Patel B., Emsley J., et al. Structural and dynamic characterization of a vinculin binding site in the talin rod. Biochemistry 2006, 45:1805-1817.
50. Goldmann W.H., Guttenberg Z., Tang J.X., Kroy K., Isenberg G., Ezzell R.M. Analysis of the F-actin binding fragments of vinculin using stopped-flow and dynamic light-scattering measurements. Eur. J. Biochem. 1998, 254:413-419.
51. Grashoff C., Hoffman B.D., Brenner M.D., Zhou R., Parsons M., Yang M.T., et al. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 2010, 466:263-266.
52. Groesch M.E., Otto J.J. Purification and characterization of an 85 kDa talin-binding fragment of vinculin. Cell Motil. Cytoskeleton 1990, 15:41-50.
53. Gumbiner B.M. Regulation of cadherin-mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 2005, 6:622-634.
54. Halegoua S. Changes in the phosphorylation and distribution of vinculin during nerve growth factor induced neurite outgrowth. Dev. Biol. 1987, 121:97-104.
55. Hamiaux C., van Eerde A., Parsot C., Broos J., Dijkstra B.W. Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri. EMBO Rep. 2006, 7:794-799.
56. Hazan R.B., Kang L., Roe S., Borgen P.I., Rimm D.L. Vinculin is associated with the E-cadherin adhesion complex. J. Biol. Chem. 1997, 272:32448-32453.
57. Hemmings L., Rees D.J., Ohanian V., Bolton S.J., Gilmore A.P., Patel B., et al. Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. J. Cell Sci. 1996, 109(Pt. 11):2715-2726.
58. Horwitz A., Duggan K., Buck C., Beckerle M.C., Burridge K. Interaction of plasma membrane fibronectin receptor with talin-a transmembrane linkage. Nature 1986, 320:531-533.
59. Hu K., Ji L., Applegate K.T., Danuser G., Waterman-Storer C.M. Differential transmission of actin motion within focal adhesions. Science 2007, 315:111-115.
60. Humphries J.D., Wang P., Streuli C., Geiger B., Humphries M.J., Ballestrem C. Vinculin controls focal adhesion formation by direct interactions with talin and actin. J. Cell Biol. 2007, 179:1043-1057.
61. Huttelmaier S., Bubeck P., Rudiger M., Jockusch B.M. Characterization of two F-actin-binding and oligomerization sites in the cell-contact protein vinculin. Eur. J. Biochem. 1997, 247:1136-1142.
62. Huttelmaier S., Mayboroda O., Harbeck B., Jarchau T., Jockusch B.M., Rudiger M. The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4, 5-bisphosphate. Curr. Biol. 1998, 8:479-488.
63. Huttelmaier S., Illenberger S., Grosheva I., Rudiger M., Singer R.H., Jockusch B.M. Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins. J. Cell Biol. 2001, 155:775-786.
64. Huveneers S., Danen E.H. Adhesion signaling-crosstalk between integrins, Src and Rho. J. Cell Sci. 2009, 122:1059-1069.
65. Hytonen V.P., Vogel V. How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism. PLoS Comput. Biol. 2008, 4:e24.
66. Imamura Y., Itoh M., Maeno Y., Tsukita S., Nagafuchi A. Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesion. J. Cell Biol. 1999, 144:1311-1322.
67. Isenberg G., Goldmann W.H. Peptide-specific antibodies localize the major lipid binding sites of talin dimers to oppositely arranged N-terminal 47 kDa subdomains. FEBS Lett. 1998, 426:165-170.
68. Isenberg G., Leonard K., Jockusch B.M. Structural aspects of vinculin-actin interactions. J. Mol. Biol. 1982, 158:231-249.
69. Izard T., Vonrhein C. Structural basis for amplifying vinculin activation by talin. J. Biol. Chem. 2004, 279:27667-27678.
70. Izard T., Evans G., Borgon R.A., Rush C.L., Bricogne G., Bois P.R. Vinculin activation by talin through helical bundle conversion. Nature 2004, 427:171-175.
71. Izard T., Tran Van Nhieu G., Bois P.R. Shigella applies molecular mimicry to subvert vinculin and invade host cells. J. Cell Biol. 2006, 175:465-475.
72. Janssen M.E., Kim E., Liu H., Fujimoto L.M., Bobkov A., Volkmann N., et al. Three-dimensional structure of vinculin bound to actin filaments. Mol. Cell 2006, 21:271-281.
73. Ji L., Lim J., Danuser G. Fluctuations of intracellular forces during cell protrusion. Nat. Cell Biol. 2008, 10:1393-1400.
74. Jockusch B.M., Isenberg G. Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation. Proc. Natl. Acad. Sci. USA 1981, 78:3005-3009.
75. Johnson R.P., Craig S.W. An intramolecular association between the head and tail domains of vinculin modulates talin binding. J. Biol. Chem. 1994, 269:12611-12619.
76. Johnson R.P., Craig S.W. The carboxy-terminal tail domain of vinculin contains a cryptic binding site for acidic phospholipids. Biochem. Biophys. Res. Commun. 1995, 210:159-164.
77. Johnson R.P., Craig S.W. F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 1995, 373:261-264.
78. Johnson R.P., Craig S.W. Actin activates a cryptic dimerization potential of the vinculin tail domain. J. Biol. Chem. 2000, 275:95-105.
79. Kawahara E., Tokuda R., Nakanishi I. Migratory phenotypes of HSC-3 squamous carcinoma cell line induced by EGF and PMA: relevance to migration of loosening of adhesion and vinculin-associated focal contacts with prominent filopodia. Cell Biol. Int. 1999, 23:163-174.
80. Kioka N., Sakata S., Kawauchi T., Amachi T., Akiyama S.K., Okazaki K., et al. Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization. J. Cell Biol. 1999, 144:59-69.
81. Koteliansky V.E., Gneushev G.N. Vinculin localization in cardiac muscle. FEBS Lett. 1983, 159:158-160.
82. Kroemker M., Rudiger A.H., Jockusch B.M., Rudiger M. Intramolecular interactions in vinculin control alpha-actinin binding to the vinculin head. FEBS Lett. 1994, 355:259-262.
83. Kupper K., Lang N., Mohl C., Kirchgessner N., Born S., Goldmann W.H., et al. Tyrosine phosphorylation of vinculin at position 1065 modifies focal adhesion dynamics and cell tractions. Biochem. Biophys. Res. Commun. 2010, 399:560-564.
84. le Duc Q., Shi Q., Blonk I., Sonnenberg A., Wang N., Leckband D., et al. Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. J. Cell Biol. 2010, 189:1107-1115.
85. Lee J.H., Rangarajan E.S., Yogesha S.D., Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure 2009, 17:833-842.
86. Lifschitz-Mercer B., Czernobilsky B., Feldberg E., Geiger B. Expression of the adherens junction protein vinculin in human basal and squamous cell tumors: relationship to invasiveness and metastatic potential. Hum. Pathol. 1997, 28:1230-1236.
87. Lombardi M.L., Knecht D.A., Dembo M., Lee J. Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement. J. Cell Sci. 2007, 120:1624-1634.
88. Lotz M.M., Burdsal C.A., Erickson H.P., McClay D.R. Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response. J. Cell Biol. 1989, 109:1795-1805.
89. Maciver S.K. Myosin II function in non-muscle cells. Bioessays 1996, 18:179-182.
90. Maddugoda M.P., Crampton M.S., Shewan A.M., Yap A.S. Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells. J. Cell Biol. 2007, 178:529-540.
91. Maeda M., Holder E., Lowes B., Valent S., Bies R.D. Dilated cardiomyopathy associated with deficiency of the cytoskeletal protein metavinculin. Circulation 1997, 95:17-20.
92. Mandai K., Nakanishi H., Satoh A., Takahashi K., Satoh K., Nishioka H., et al. Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J. Cell Biol. 1999, 144:1001-1017.
93. Massa R., Silvestri G., Sancesario G., Bernardi G. Immunocytochemical localization of vinculin in muscle and nerve. Muscle Nerve 1995, 18:1277-1284.
94. McCann R.O., Craig S.W. The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals. Proc. Natl. Acad. Sci. USA 1997, 94:5679-5684.
95. Menard R., Sansonetti P.J., Parsot C. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J. Bacteriol. 1993, 175:5899-5906.
96. Menkel A.R., Kroemker M., Bubeck P., Ronsiek M., Nikolai G., Jockusch B.M. Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin. J. Cell Biol. 1994, 126:1231-1240.
97. Meyer T., Brinck U. Immunohistochemical detection of vinculin in human rhabdomyosarcomas. Gen. Diagn. Pathol. 1997, 142:191-198.
98. Mierke C.T., Kollmannsberger P., Zitterbart D.P., Smith J., Fabry B., Goldmann W.H. Mechano-coupling and regulation of contractility by the vinculin tail domain. Biophys. J. 2008, 94:661-670.
99. Mierke C.T., Kollmannsberger P., Zitterbart D.P., Diez G., Koch T.M., Marg S., et al. Vinculin facilitates cell invasion into three-dimensional collagen matrices. J. Biol. Chem. 2010, 285:13121-13130.
100. Milam L.M. Electron microscopy of rotary shadowed vinculin and vinculin complexes. J. Mol. Biol. 1985, 184:543-545.
101. Miller G.J., Dunn S.D., Ball E.H. Interaction of the N- and C-terminal domains of vinculin. Characterization and mapping studies. J. Biol. Chem. 2001, 276:11729-11734.
102. Moese S., Selbach M., Brinkmann V., Karlas A., Haimovich B., Backert S., et al. The Helicobacter pylori CagA protein disrupts matrix adhesion of gastric epithelial cells by dephosphorylation of vinculin. Cell. Microbiol. 2007, 9:1148-1161.
103. Mohl C., Kirchgessner N., Schafer C., Kupper K., Born S., Diez G., et al. Becoming stable and strong: the interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation. Cell Motil. Cytoskeleton 2009, 66:350-364.
104. Molony L., Burridge K. Molecular shape and self-association of vinculin and metavinculin. J. Cell. Biochem. 1985, 29:31-36.
105. Niessen C.M., Gottardi C.J. Molecular components of the adherens junction. Biochim. Biophys. Acta 2008, 1778:562-571.
106. Nishimura T., Takeichi M. Remodeling of the adherens junctions during morphogenesis. Curr. Top. Dev. Biol. 2009, 89:33-54.
107. Nolz J.C., Medeiros R.B., Mitchell J.S., Zhu P., Freedman B.D., Shimizu Y., et al. WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse. Mol. Cell. Biol. 2007, 27:5986-6000.
108. Noorman M., van der Heyden M.A., van Veen T.A., Cox M.G., Hauer R.N., de Bakker J.M., et al. Cardiac cell-cell junctions in health and disease: electrical versus mechanical coupling. J. Mol. Cell. Cardiol. 2009, 47:23-31.
109. Obrink B. Epithelial cell adhesion molecules. Exp. Cell Res. 1986, 163:1-21.
110. Ogita H., Takai Y. Cross-talk among integrin, cadherin, and growth factor receptor: roles of nectin and nectin-like molecule. Int. Rev. Cytol. 2008, 265:1-54.
111. Ohmori T., Kashiwakura Y., Ishiwata A., Madoiwa S., Mimuro J., Honda S., et al. Vinculin activates inside-out signaling of integrin alphaIIbbeta3 in Chinese hamster ovary cells. Biochem. Biophys. Res. Commun. 2010, 400:323-328.
112. Olson T.M., Illenberger S., Kishimoto N.Y., Huttelmaier S., Keating M.T., Jockusch B.M. Metavinculin mutations alter actin interaction in dilated cardiomyopathy. Circulation 2002, 105:431-437.
113. Opas M., Turksen K., Kalnins V.I. Adhesiveness and distribution of vinculin and spectrin in retinal pigmented epithelial cells during growth and differentiation in vitro. Dev. Biol. 1985, 107:269-280.
114. Otto J.J. The lack of interaction between vinculin and actin. Cell Motil. Cytoskeleton 1986, 6:48-55.
115. Pantaloni D., Le Clainche C., Carlier M.F. Mechanism of actin-based motility. Science 2001, 292:1502-1506.
116. Papagrigoriou E., Gingras A.R., Barsukov I.L., Bate N., Fillingham I.J., Patel B., et al. Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. EMBO J. 2004, 23:2942-2951.
117. Pardo J.V., Siliciano J.D., Craig S.W. A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements ("costameres") mark sites of attachment between myofibrils and sarcolemma. Proc. Natl. Acad. Sci. USA 1983, 80:1008-1012.
118. Pardo J.V., Siliciano J.D., Craig S.W. Vinculin is a component of an extensive network of myofibril-sarcolemma attachment regions in cardiac muscle fibers. J. Cell Biol. 1983, 97:1081-1088.
119. Pasapera A.M., Schneider I.C., Rericha E., Schlaepfer D.D., Waterman C.M. Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J. Cell Biol. 2010, 188:877-890.
120. Patel B., Gingras A.R., Bobkov A.A., Fujimoto L.M., Zhang M., Liddington R.C., et al. The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod. J. Biol. Chem. 2006, 281:7458-7467.
121. Peng X., Cuff L.E., Lawton C.D., DeMali K.A. Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin. J. Cell Sci. 2010, 123:567-577.
122. Perez-Moreno M., Fuchs E. Catenins: keeping cells from getting their signals crossed. Dev. Cell 2006, 11:601-612.
123. Pokutta S., Drees F., Takai Y., Nelson W.J., Weis W.I. Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J. Biol. Chem. 2002, 277:18868-18874.
124. Pollard T.D., Borisy G.G. Cellular motility driven by assembly and disassembly of actin filaments. Cell 2003, 112:453-465.
125. Prutzman K.C., Gao G., King M.L., Iyer V.V., Mueller G.A., Schaller M.D., et al. The focal adhesion targeting domain of focal adhesion kinase contains a hinge region that modulates tyrosine 926 phosphorylation. Structure 2004, 12:881-891.
126. Ramarao N., Le Clainche C., Izard T., Bourdet-Sicard R., Ageron E., Sansonetti P.J., et al. Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain. FEBS Lett. 2007, 581:853-857.
127. Ridley A.J., Schwartz M.A., Burridge K., Firtel R.A., Ginsberg M.H., Borisy G., et al. Cell migration: integrating signals from front to back. Science 2003, 302:1704-1709.
128. Rodriguez Fernandez J.L., Geiger B., Salomon D., Sabanay I., Zoller M., Ben-Ze'ev A. Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA. J. Cell Biol. 1992, 119:427-438.
129. Rosenfeld G.C., Hou D.C., Dingus J., Meza I., Bryan J. Isolation and partial characterization of human platelet vinculin. J. Cell Biol. 1985, 100:669-676.
130. Sadano H., Inoue M., Taniguchi S. Differential expression of vinculin between weakly and highly metastatic B16-melanoma cell lines. Jpn. J. Cancer Res. 1992, 83:625-630.
131. Samarel A.M. Costameres, focal adhesions, and cardiomyocyte mechanotransduction. Am. J. Physiol. Heart Circ. Physiol. 2005, 289:H2291-H2301.
132. Saunders R.M., Holt M.R., Jennings L., Sutton D.H., Barsukov I.L., Bobkov A., et al. Role of vinculin in regulating focal adhesion turnover. Eur. J. Cell Biol. 2006, 85:487-500.
133. Sawicka K., Bushell M., Spriggs K.A., Willis A.E. Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein. Biochem. Soc. Trans. 2008, 36:641-647.
134. Schindeler A., Lavulo L., Harvey R.P. Muscle costameric protein, Chisel/Smpx, associates with focal adhesion complexes and modulates cell spreading in vitro via a Rac1/p38 pathway. Exp. Cell Res. 2005, 307:367-380.
135. Schwartz M.A., DeSimone D.W. Cell adhesion receptors in mechanotransduction. Curr. Opin. Cell Biol. 2008, 20:551-556.
136. Schwienbacher C., Jockusch B.M., Rudiger M. Intramolecular interactions regulate serine/threonine phosphorylation of vinculin. FEBS Lett. 1996, 384:71-74.
137. Sefton B.M., Hunter T., Ball E.H., Singer S.J. Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell 1981, 24:165-174.
138. Sharp W.W., Simpson D.G., Borg T.K., Samarel A.M., Terracio L. Mechanical forces regulate focal adhesion and costamere assembly in cardiac myocytes. Am. J. Physiol. 1997, 273:H546-H556.
139. Sheikh F., Chen Y., Liang X., Hirschy A., Stenbit A.E., Gu Y., et al. Alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation 2006, 114:1046-1055.
140. Somiari R.I., Sullivan A., Russell S., Somiari S., Hu H., Jordan R., et al. High-throughput proteomic analysis of human infiltrating ductal carcinoma of the breast. Proteomics 2003, 3:1863-1873.
141. Steimle P.A., Hoffert J.D., Adey N.B., Craig S.W. Polyphosphoinositides inhibit the interaction of vinculin with actin filaments. J. Biol. Chem. 1999, 274:18414-18420.
142. Stricker J., Falzone T., Gardel M.L. Mechanics of the F-actin cytoskeleton. J. Biomech. 2010, 43:9-14.
143. Subauste M.C., Pertz O., Adamson E.D., Turner C.E., Junger S., Hahn K.M. Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J. Cell Biol. 2004, 165:371-381.
144. Takahashi H., Mitsushima M., Okada N., Ito T., Aizawa S., Akahane R., et al. Role of interaction with vinculin in recruitment of vinexins to focal adhesions. Biochem. Biophys. Res. Commun. 2005, 336:239-246.
145. Terracio L., Simpson D.G., Hilenski L., Carver W., Decker R.S., Vinson N., et al. Distribution of vinculin in the Z-disk of striated muscle: analysis by laser scanning confocal microscopy. J. Cell. Physiol. 1990, 145:78-87.
146. Tidball J.G., Spencer M.J. PDGF stimulation induces phosphorylation of talin and cytoskeletal reorganization in skeletal muscle. J. Cell Biol. 1993, 123:627-635.
147. Tran Van Nhieu G., Ben-Ze'ev A., Sansonetti P.J. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. EMBO J. 1997, 16:2717-2729.
148. Tremuth L., Kreis S., Melchior C., Hoebeke J., Ronde P., Plancon S., et al. A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain. J. Biol. Chem. 2004, 279:22258-22266.
149. Turner C.E., Glenney J.R., Burridge K. Paxillin: a new vinculin-binding protein present in focal adhesions. J. Cell Biol. 1990, 111:1059-1068.
150. Vasile V.C., Edwards W.D., Ommen S.R., Ackerman M.J. Obstructive hypertrophic cardiomyopathy is associated with reduced expression of vinculin in the intercalated disc. Biochem. Biophys. Res. Commun. 2006, 349:709-715.
151. Vasile V.C., Ommen S.R., Edwards W.D., Ackerman M.J. A missense mutation in a ubiquitously expressed protein, vinculin, confers susceptibility to hypertrophic cardiomyopathy. Biochem. Biophys. Res. Commun. 2006, 345:998-1003.
152. Vasile V.C., Will M.L., Ommen S.R., Edwards W.D., Olson T.M., Ackerman M.J. Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy. Mol. Genet. Metab. 2006, 87:169-174.
153. Verkhovsky A.B., Svitkina T.M., Borisy G.G. Network contraction model for cell translocation and retrograde flow. Biochem. Soc. Symp. 1999, 65:207-222.
154. Volberg T., Geiger B., Kam Z., Pankov R., Simcha I., Sabanay H., et al. Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption. J. Cell Sci. 1995, 108(Pt. 6):2253-2260.
155. Volk T., Geiger B. A 135-kd membrane protein of intercellular adherens junctions. EMBO J. 1984, 3:2249-2260.
156. Vostal J.G., Shulman N.R. Vinculin is a major platelet protein that undergoes calcium ion-dependent tyrosine phosphorylation. Biochem. J. 1993, 294:675-680.
157. Watabe-Uchida M., Uchida N., Imamura Y., Nagafuchi A., Fujimoto K., Uemura T., et al. alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells. J. Cell Biol. 1998, 142:847-857.
158. Weekes J., Barry S.T., Critchley D.R. Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites. Biochem. J. 1996, 314(Pt. 3):827-832.
159. Weiss E.E., Kroemker M., Rudiger A.H., Jockusch B.M., Rudiger M. Vinculin is part of the cadherin-catenin junctional complex: complex formation between alpha-catenin and vinculin. J. Cell Biol. 1998, 141:755-764.
160. Wen K.K., Rubenstein P.A., DeMali K.A. Vinculin nucleates actin polymerization and modifies actin filament structure. J. Biol. Chem. 2009, 284:30463-30473.
161. Wilkins J.A., Lin S. High-affinity interaction of vinculin with actin filaments in vitro. Cell 1982, 28:83-90.
162. Wilkins J.A., Lin S. A re-examination of the interaction of vinculin with actin. J. Cell Biol. 1986, 102:1085-1092.
163. Winkler J., Jockusch B.M. 3-Dimensional organization of the N-terminal vinculin head fragment. Eur. J. Cell Biol. 2001, 80:201-206.
164. Winkler J., Lunsdorf H., Jockusch B.M. The ultrastructure of chicken gizzard vinculin as visualized by high-resolution electron microscopy. J. Struct. Biol. 1996, 116:270-277.
165. Winkler J., Lunsdorf H., Jockusch B.M. Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains. Eur. J. Biochem. 1997, 243:430-436.
166. Wood C.K., Turner C.E., Jackson P., Critchley D.R. Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin. J. Cell Sci. 1994, 107(Pt. 2):709-717.
167. Xing B., Jedsadayanmata A., Lam S.C. Localization of an integrin binding site to the C terminus of talin. J. Biol. Chem. 2001, 276:44373-44378.
168. Xu W., Baribault H., Adamson E.D. Vinculin knockout results in heart and brain defects during embryonic development. Development 1998, 125:327-337.
169. Xu W., Coll J.L., Adamson E.D. Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin. J. Cell Sci. 1998, 111(Pt. 11):1535-1544.
170. Yamada S., Pokutta S., Drees F., Weis W.I., Nelson W.J. Deconstructing the cadherin-catenin-actin complex. Cell 2005, 123:889-901.
171. Yang J., Dokurno P., Tonks N.K., Barford D. Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion. EMBO J. 2001, 20:3645-3656.
172. Ylanne J., Scheffzek K., Young P., Saraste M. Crystal structure of the alpha-actinin rod reveals an extensive torsional twist. Structure 2001, 9:597-604.
173. Yonemura S., Wada Y., Watanabe T., Nagafuchi A., Shibata M. alpha-Catenin as a tension transducer that induces adherens junction development. Nat. Cell Biol. 2010, 12:533-542.
174. Zemljic-Harpf A.E., Ponrartana S., Avalos R.T., Jordan M.C., Roos K.P., Dalton N.D. Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathy. Am. J. Pathol. 2004, 165:1033-1044.
175. Zemljic-Harpf A.E., Miller J.C., Henderson S.A., Wright A.T., Manso A.M., Elsherif L., et al. Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol. Cell. Biol. 2007, 27:7522-7537.
176. Zhang Z., Izaguirre G., Lin S.Y., Lee H.Y., Schaefer E., Haimovich B. The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading. Mol. Biol. Cell 2004, 15:4234-4247.
177. Ziegler W.H., Tigges U., Zieseniss A., Jockusch B.M. A lipid-regulated docking site on vinculin for protein kinase C. J. Biol. Chem. 2002, 277:7396-7404.
178. Ziegler W.H., Liddington R.C., Critchley D.R. The structure and regulation of vinculin. Trends Cell Biol. 2006, 16:453-460.
179. Zimerman B., Volberg T., Geiger B. Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading. Cell Motil. Cytoskeleton 2004, 58:143-159.