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Volumn 67, Issue 5, 2010, Pages 797-809

CDK5 Serves as a Major Control Point in Neurotransmitter Release

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 5; VESICULAR GLUTAMATE TRANSPORTER 1; 2-AMINO-5-PHOSPHOPENTANOIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AMINO ACID RECEPTOR BLOCKING AGENT; CDK5 PROTEIN, RAT; GREEN FLUORESCENT PROTEIN; MUNC18 PROTEIN; PROTEIN KINASE INHIBITOR; PURINE DERIVATIVE; ROSCOVITINE; SMALL INTERFERING RNA; SODIUM CHANNEL BLOCKING AGENT; SYNAPTOBREVIN 2; TETRODOTOXIN; VALINE;

EID: 77956314453     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2010.08.003     Document Type: Article
Times cited : (222)

References (49)
  • 3
    • 38049180885 scopus 로고    scopus 로고
    • Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode
    • Balaji J., Ryan T.A. Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode. Proc. Natl. Acad. Sci. USA 2007, 104:20576-20581.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20576-20581
    • Balaji, J.1    Ryan, T.A.2
  • 4
    • 0037199958 scopus 로고    scopus 로고
    • Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35
    • Cheng K., Li Z., Fu W.Y., Wang J.H., Fu A.K., Ip N.Y. Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J. Biol. Chem. 2002, 277:31988-31993.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31988-31993
    • Cheng, K.1    Li, Z.2    Fu, W.Y.3    Wang, J.H.4    Fu, A.K.5    Ip, N.Y.6
  • 5
    • 1242274335 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
    • Chergui K., Svenningsson P., Greengard P. Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum. Proc. Natl. Acad. Sci. USA 2004, 101:2191-2196.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2191-2196
    • Chergui, K.1    Svenningsson, P.2    Greengard, P.3
  • 7
    • 0035510916 scopus 로고    scopus 로고
    • The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis
    • Cousin M.A., Robinson P.J. The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis. Trends Neurosci. 2001, 24:659-665.
    • (2001) Trends Neurosci. , vol.24 , pp. 659-665
    • Cousin, M.A.1    Robinson, P.J.2
  • 8
    • 4444262625 scopus 로고    scopus 로고
    • Cdk5 deregulation in the pathogenesis of Alzheimer's disease
    • Cruz J.C., Tsai L.H. Cdk5 deregulation in the pathogenesis of Alzheimer's disease. Trends Mol. Med. 2004, 10:452-458.
    • (2004) Trends Mol. Med. , vol.10 , pp. 452-458
    • Cruz, J.C.1    Tsai, L.H.2
  • 9
    • 33745734146 scopus 로고    scopus 로고
    • Homeostatic control of neural activity: from phenomenology to molecular design
    • Davis G.W. Homeostatic control of neural activity: from phenomenology to molecular design. Annu. Rev. Neurosci. 2006, 29:307-323.
    • (2006) Annu. Rev. Neurosci. , vol.29 , pp. 307-323
    • Davis, G.W.1
  • 10
    • 0037107152 scopus 로고    scopus 로고
    • The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner
    • Dhavan R., Greer P.L., Morabito M.A., Orlando L.R., Tsai L.H. The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner. J. Neurosci. 2002, 22:7879-7891.
    • (2002) J. Neurosci. , vol.22 , pp. 7879-7891
    • Dhavan, R.1    Greer, P.L.2    Morabito, M.A.3    Orlando, L.R.4    Tsai, L.H.5
  • 11
    • 33745916308 scopus 로고    scopus 로고
    • The efficiency of the synaptic vesicle cycle at central nervous system synapses
    • Fernández-Alfonso T., Ryan T.A. The efficiency of the synaptic vesicle cycle at central nervous system synapses. Trends Cell Biol. 2006, 16:413-420.
    • (2006) Trends Cell Biol. , vol.16 , pp. 413-420
    • Fernández-Alfonso, T.1    Ryan, T.A.2
  • 12
    • 57049173371 scopus 로고    scopus 로고
    • A heterogeneous " resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses
    • Fernandez-Alfonso T., Ryan T.A. A heterogeneous " resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses. Brain Cell Biol. 2008, 36:87-100.
    • (2008) Brain Cell Biol. , vol.36 , pp. 87-100
    • Fernandez-Alfonso, T.1    Ryan, T.A.2
  • 14
    • 60449085252 scopus 로고    scopus 로고
    • A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels
    • Frank C.A., Pielage J., Davis G.W. A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels. Neuron 2009, 61:556-569.
    • (2009) Neuron , vol.61 , pp. 556-569
    • Frank, C.A.1    Pielage, J.2    Davis, G.W.3
  • 15
    • 66749149541 scopus 로고    scopus 로고
    • A resting pool of vesicles is responsible for spontaneous vesicle fusion at the synapse
    • Fredj N.B., Burrone J. A resting pool of vesicles is responsible for spontaneous vesicle fusion at the synapse. Nat. Neurosci. 2009, 12:751-758.
    • (2009) Nat. Neurosci. , vol.12 , pp. 751-758
    • Fredj, N.B.1    Burrone, J.2
  • 16
    • 33846612037 scopus 로고    scopus 로고
    • Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool
    • Groemer T.W., Klingauf J. Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool. Nat. Neurosci. 2007, 10:145-147.
    • (2007) Nat. Neurosci. , vol.10 , pp. 145-147
    • Groemer, T.W.1    Klingauf, J.2
  • 17
    • 0035940483 scopus 로고    scopus 로고
    • Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photoconversion
    • Harata N., Ryan T.A., Smith S.J., Buchanan J., Tsien R.W. Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photoconversion. Proc. Natl. Acad. Sci. USA 2001, 98:12748-12753.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12748-12753
    • Harata, N.1    Ryan, T.A.2    Smith, S.J.3    Buchanan, J.4    Tsien, R.W.5
  • 19
    • 0034647593 scopus 로고    scopus 로고
    • Synaptic localization of p39, a neuronal activator of cdk5
    • Humbert S., Lanier L.M., Tsai L.H. Synaptic localization of p39, a neuronal activator of cdk5. Neuroreport 2000, 11:2213-2216.
    • (2000) Neuroreport , vol.11 , pp. 2213-2216
    • Humbert, S.1    Lanier, L.M.2    Tsai, L.H.3
  • 21
    • 70450225366 scopus 로고    scopus 로고
    • A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis
    • Kim S.H., Ryan T.A. A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis. J. Biol. Chem. 2009, 284:32803-32812.
    • (2009) J. Biol. Chem. , vol.284 , pp. 32803-32812
    • Kim, S.H.1    Ryan, T.A.2
  • 22
    • 64849102896 scopus 로고    scopus 로고
    • Synaptic vesicle recycling at CNS snapses without AP-2
    • Kim S.H., Ryan T.A. Synaptic vesicle recycling at CNS snapses without AP-2. J. Neurosci. 2009, 29:3865-3874.
    • (2009) J. Neurosci. , vol.29 , pp. 3865-3874
    • Kim, S.H.1    Ryan, T.A.2
  • 23
  • 24
    • 0033660866 scopus 로고    scopus 로고
    • The role of the p35/cdk5 kinase in cortical development
    • Kwon Y.T., Tsai L.H. The role of the p35/cdk5 kinase in cortical development. Results Probl. Cell Differ. 2000, 30:241-253.
    • (2000) Results Probl. Cell Differ. , vol.30 , pp. 241-253
    • Kwon, Y.T.1    Tsai, L.H.2
  • 27
    • 33744545575 scopus 로고    scopus 로고
    • Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis
    • Liu Y., Cheng K., Gong K., Fu A.K., Ip N.Y. Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. J. Biol. Chem. 2006, 281:9852-9858.
    • (2006) J. Biol. Chem. , vol.281 , pp. 9852-9858
    • Liu, Y.1    Cheng, K.2    Gong, K.3    Fu, A.K.4    Ip, N.Y.5
  • 28
    • 0029829890 scopus 로고    scopus 로고
    • Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions
    • Matsubara M., Kusubata M., Ishiguro K., Uchida T., Titani K., Taniguchi H. Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions. J. Biol. Chem. 1996, 271:21108-21113.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21108-21113
    • Matsubara, M.1    Kusubata, M.2    Ishiguro, K.3    Uchida, T.4    Titani, K.5    Taniguchi, H.6
  • 29
    • 0035923749 scopus 로고    scopus 로고
    • Inactivity produces increases in neurotransmitter release and synapse size
    • Murthy V.N., Schikorski T., Stevens C.F., Zhu Y. Inactivity produces increases in neurotransmitter release and synapse size. Neuron 2001, 32:673-682.
    • (2001) Neuron , vol.32 , pp. 673-682
    • Murthy, V.N.1    Schikorski, T.2    Stevens, C.F.3    Zhu, Y.4
  • 31
    • 0033557648 scopus 로고    scopus 로고
    • Inhibitors of myosin light chain kinase block synaptic vesicle pool mobilization during action potential firing
    • Ryan T.A. Inhibitors of myosin light chain kinase block synaptic vesicle pool mobilization during action potential firing. J. Neurosci. 1999, 19:1317-1323.
    • (1999) J. Neurosci. , vol.19 , pp. 1317-1323
    • Ryan, T.A.1
  • 32
    • 0029062202 scopus 로고
    • Vesicle pool mobilization during action potential firing at hippocampal synapses
    • Ryan T.A., Smith S.J. Vesicle pool mobilization during action potential firing at hippocampal synapses. Neuron 1995, 14:983-989.
    • (1995) Neuron , vol.14 , pp. 983-989
    • Ryan, T.A.1    Smith, S.J.2
  • 35
    • 0035146137 scopus 로고    scopus 로고
    • Calcium accelerates endocytosis of vSNAREs at hippocampal synapses
    • Sankaranarayanan S., Ryan T.A. Calcium accelerates endocytosis of vSNAREs at hippocampal synapses. Nat. Neurosci. 2001, 4:129-136.
    • (2001) Nat. Neurosci. , vol.4 , pp. 129-136
    • Sankaranarayanan, S.1    Ryan, T.A.2
  • 36
    • 0033803597 scopus 로고    scopus 로고
    • The use of pHluorins for optical measurements of presynaptic activity
    • Sankaranarayanan S., De Angelis D., Rothman J.E., Ryan T.A. The use of pHluorins for optical measurements of presynaptic activity. Biophys. J. 2000, 79:2199-2208.
    • (2000) Biophys. J. , vol.79 , pp. 2199-2208
    • Sankaranarayanan, S.1    De Angelis, D.2    Rothman, J.E.3    Ryan, T.A.4
  • 37
    • 13844266201 scopus 로고    scopus 로고
    • An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission
    • Sara Y., Virmani T., Deák F., Liu X., Kavalali E.T. An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission. Neuron 2005, 45:563-573.
    • (2005) Neuron , vol.45 , pp. 563-573
    • Sara, Y.1    Virmani, T.2    Deák, F.3    Liu, X.4    Kavalali, E.T.5
  • 38
    • 0032570795 scopus 로고    scopus 로고
    • Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings
    • Shuang R., Zhang L., Fletcher A., Groblewski G.E., Pevsner J., Stuenkel E.L. Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. J. Biol. Chem. 1998, 273:4957-4966.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4957-4966
    • Shuang, R.1    Zhang, L.2    Fletcher, A.3    Groblewski, G.E.4    Pevsner, J.5    Stuenkel, E.L.6
  • 41
    • 0037137469 scopus 로고    scopus 로고
    • Alpha- and betaCaMKII. Inverse regulation by neuronal activity and opposing effects on synaptic strength
    • Thiagarajan T.C., Piedras-Renteria E.S., Tsien R.W. alpha- and betaCaMKII. Inverse regulation by neuronal activity and opposing effects on synaptic strength. Neuron 2002, 36:1103-1114.
    • (2002) Neuron , vol.36 , pp. 1103-1114
    • Thiagarajan, T.C.1    Piedras-Renteria, E.S.2    Tsien, R.W.3
  • 42
    • 23944511446 scopus 로고    scopus 로고
    • Adaptation to synaptic inactivity in hippocampal neurons
    • Thiagarajan T.C., Lindskog M., Tsien R.W. Adaptation to synaptic inactivity in hippocampal neurons. Neuron 2005, 47:725-737.
    • (2005) Neuron , vol.47 , pp. 725-737
    • Thiagarajan, T.C.1    Lindskog, M.2    Tsien, R.W.3
  • 43
    • 0036546687 scopus 로고    scopus 로고
    • Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity
    • Tomizawa K., Ohta J., Matsushita M., Moriwaki A., Li S.T., Takei K., Matsui H. Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity. J. Neurosci. 2002, 22:2590-2597.
    • (2002) J. Neurosci. , vol.22 , pp. 2590-2597
    • Tomizawa, K.1    Ohta, J.2    Matsushita, M.3    Moriwaki, A.4    Li, S.T.5    Takei, K.6    Matsui, H.7
  • 45
    • 54549125798 scopus 로고    scopus 로고
    • The self-tuning neuron: synaptic scaling of excitatory synapses
    • Turrigiano G.G. The self-tuning neuron: synaptic scaling of excitatory synapses. Cell 2008, 135:422-435.
    • (2008) Cell , vol.135 , pp. 422-435
    • Turrigiano, G.G.1
  • 46
    • 33745494172 scopus 로고    scopus 로고
    • Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling
    • Voglmaier S.M., Kam K., Yang H., Fortin D.L., Hua Z., Nicoll R.A., Edwards R.H. Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling. Neuron 2006, 51:71-84.
    • (2006) Neuron , vol.51 , pp. 71-84
    • Voglmaier, S.M.1    Kam, K.2    Yang, H.3    Fortin, D.L.4    Hua, Z.5    Nicoll, R.A.6    Edwards, R.H.7
  • 47
    • 35048891437 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 (Cdk5): a potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus
    • Wei F.Y., Tomizawa K. Cyclin-dependent kinase 5 (Cdk5): a potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus. Mini Rev. Med. Chem. 2007, 7:1070-1074.
    • (2007) Mini Rev. Med. Chem. , vol.7 , pp. 1070-1074
    • Wei, F.Y.1    Tomizawa, K.2
  • 48
    • 0036588343 scopus 로고    scopus 로고
    • Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons
    • Yan Z., Chi P., Bibb J.A., Ryan T.A., Greengard P. Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons. J. Physiol. 2002, 540:761-770.
    • (2002) J. Physiol. , vol.540 , pp. 761-770
    • Yan, Z.1    Chi, P.2    Bibb, J.A.3    Ryan, T.A.4    Greengard, P.5
  • 49
    • 0035977139 scopus 로고    scopus 로고
    • Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory
    • Zeng H., Chattarji S., Barbarosie M., Rondi-Reig L., Philpot B.D., Miyakawa T., Bear M.F., Tonegawa S. Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell 2001, 107:617-629.
    • (2001) Cell , vol.107 , pp. 617-629
    • Zeng, H.1    Chattarji, S.2    Barbarosie, M.3    Rondi-Reig, L.4    Philpot, B.D.5    Miyakawa, T.6    Bear, M.F.7    Tonegawa, S.8


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