메뉴 건너뛰기




Volumn 369, Issue 4, 2007, Pages 967-984

The Role of STAT1/IRF-1 on Synergistic ROS Production and Loss of Mitochondrial Transmembrane Potential during Hepatic Cell Death Induced by LPS/d-GalN

Author keywords

hepatitis; iNOS; liver injury; ROS; STAT1

Indexed keywords

ACETYLCYSTEINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GALACTOSAMINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; LIPOPOLYSACCHARIDE; N(G) METHYLARGININE; NITRIC OXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 34248579219     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.03.072     Document Type: Article
Times cited : (55)

References (40)
  • 2
    • 33644894450 scopus 로고    scopus 로고
    • Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and d-galactosamine in mice
    • Wang H., and Li Y. Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and d-galactosamine in mice. Eur. J. Pharmacol. 534 (2006) 194-201
    • (2006) Eur. J. Pharmacol. , vol.534 , pp. 194-201
    • Wang, H.1    Li, Y.2
  • 3
    • 17744371331 scopus 로고    scopus 로고
    • TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
    • Dumitru C.D., Ceci J.D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J.H., et al. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 103 (2000) 1071-1083
    • (2000) Cell , vol.103 , pp. 1071-1083
    • Dumitru, C.D.1    Ceci, J.D.2    Tsatsanis, C.3    Kontoyiannis, D.4    Stamatakis, K.5    Lin, J.H.6
  • 4
    • 33646074538 scopus 로고    scopus 로고
    • Agonistic antibody to TLR4/MD-2 protects mice from acute lethal hepatitis induced by TNF-alpha
    • Akashi-Takamura S., Furuta T., Takahashi K., Tanimura N., Kusumoto Y., Kobayashi T., et al. Agonistic antibody to TLR4/MD-2 protects mice from acute lethal hepatitis induced by TNF-alpha. J. Immunol. 176 (2006) 4244-4251
    • (2006) J. Immunol. , vol.176 , pp. 4244-4251
    • Akashi-Takamura, S.1    Furuta, T.2    Takahashi, K.3    Tanimura, N.4    Kusumoto, Y.5    Kobayashi, T.6
  • 5
    • 33644516973 scopus 로고    scopus 로고
    • Suppression of TNFalpha production in LPS induced liver failure in mice after intravenous injection of cationic liposomes/NFkappaB decoy complex
    • Higuchi Y., Kawakami S., Oka M., Yamashita F., and Hashida M. Suppression of TNFalpha production in LPS induced liver failure in mice after intravenous injection of cationic liposomes/NFkappaB decoy complex. Pharmazie 61 (2006) 144-147
    • (2006) Pharmazie , vol.61 , pp. 144-147
    • Higuchi, Y.1    Kawakami, S.2    Oka, M.3    Yamashita, F.4    Hashida, M.5
  • 6
    • 16644383355 scopus 로고    scopus 로고
    • Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury
    • Ding W.X., and Yin X.M. Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury. J. Cell Mol. Med. 8 (2004) 445-454
    • (2004) J. Cell Mol. Med. , vol.8 , pp. 445-454
    • Ding, W.X.1    Yin, X.M.2
  • 7
    • 0029745414 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced glomerulonephritis develops in the absence of interferon-gamma signaling
    • Haas C., Car B., Ryffel B., and Le Hir M. Lipopolysaccharide-induced glomerulonephritis develops in the absence of interferon-gamma signaling. Exp. Nephrol. 4 (1996) 222-230
    • (1996) Exp. Nephrol. , vol.4 , pp. 222-230
    • Haas, C.1    Car, B.2    Ryffel, B.3    Le Hir, M.4
  • 8
    • 0033968237 scopus 로고    scopus 로고
    • Role of interferon-gamma and nitric oxide in pulmonary edema and death induced by lipopolysaccharide
    • Heremans H., Dillen C., Groenen M., Matthys P., and Billiau A. Role of interferon-gamma and nitric oxide in pulmonary edema and death induced by lipopolysaccharide. Am. J. Respir. Crit. Care. Med. 161 (2000) 110-117
    • (2000) Am. J. Respir. Crit. Care. Med. , vol.161 , pp. 110-117
    • Heremans, H.1    Dillen, C.2    Groenen, M.3    Matthys, P.4    Billiau, A.5
  • 9
    • 0036854891 scopus 로고    scopus 로고
    • Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS
    • Hong F., Jaruga B., Kim W.H., Radaeva S., El Assal O.N., Tian Z., et al. Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J. Clin. Invest. 110 (2002) 1503-1513
    • (2002) J. Clin. Invest. , vol.110 , pp. 1503-1513
    • Hong, F.1    Jaruga, B.2    Kim, W.H.3    Radaeva, S.4    El Assal, O.N.5    Tian, Z.6
  • 11
    • 7044235774 scopus 로고    scopus 로고
    • IFN-gamma/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: a critical role of IRF-1
    • Jaruga B., Hong F., Kim W.H., and Gao B. IFN-gamma/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: a critical role of IRF-1. Am. J. Physiol. Gastrointest. Liver. Physiol. 287 (2004) G1044-G1052
    • (2004) Am. J. Physiol. Gastrointest. Liver. Physiol. , vol.287
    • Jaruga, B.1    Hong, F.2    Kim, W.H.3    Gao, B.4
  • 12
    • 0034023105 scopus 로고    scopus 로고
    • Liver infiltrating T lymphocytes express interferon gamma and inducible nitric oxide synthase in chronic hepatitis C virus infection
    • Schweyer S., Mihm S., Radzun H.J., Hartmann H., and Fayyazi A. Liver infiltrating T lymphocytes express interferon gamma and inducible nitric oxide synthase in chronic hepatitis C virus infection. Gut 46 (2000) 255-259
    • (2000) Gut , vol.46 , pp. 255-259
    • Schweyer, S.1    Mihm, S.2    Radzun, H.J.3    Hartmann, H.4    Fayyazi, A.5
  • 13
    • 0035110655 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice
    • Sass G., Koerber K., Bang R., Guehring H., and Tiegs G. Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice. J. Clin. Invest. 107 (2001) 439-447
    • (2001) J. Clin. Invest. , vol.107 , pp. 439-447
    • Sass, G.1    Koerber, K.2    Bang, R.3    Guehring, H.4    Tiegs, G.5
  • 14
    • 7244251960 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins
    • Guler R., Olleros M.L., Vesin D., Parapanov R., Vesin C., Kantengwa S., et al. Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins. J. Hepatol. 41 (2004) 773-781
    • (2004) J. Hepatol. , vol.41 , pp. 773-781
    • Guler, R.1    Olleros, M.L.2    Vesin, D.3    Parapanov, R.4    Vesin, C.5    Kantengwa, S.6
  • 15
    • 16244370418 scopus 로고    scopus 로고
    • Coexposure of lead- and lipopolysaccharide-induced liver injury in rats: involvement of nitric oxide-initiated oxidative stress and TNF-alpha
    • Liu M.Y., Cheng Y.J., Chen C.K., and Yang B.C. Coexposure of lead- and lipopolysaccharide-induced liver injury in rats: involvement of nitric oxide-initiated oxidative stress and TNF-alpha. Shock 23 (2005) 360-364
    • (2005) Shock , vol.23 , pp. 360-364
    • Liu, M.Y.1    Cheng, Y.J.2    Chen, C.K.3    Yang, B.C.4
  • 17
    • 0037042185 scopus 로고    scopus 로고
    • Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver
    • Kondo S., Toyokuni S., Tsuruyama T., Ozeki M., Tachibana T., Echizenya M., et al. Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver. Cancer Lett. 179 (2002) 87-93
    • (2002) Cancer Lett. , vol.179 , pp. 87-93
    • Kondo, S.1    Toyokuni, S.2    Tsuruyama, T.3    Ozeki, M.4    Tachibana, T.5    Echizenya, M.6
  • 18
    • 5644250881 scopus 로고    scopus 로고
    • Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies
    • Vodovotz Y., Kim P.K., Bagci E.Z., Ermentrout G.B., Chow C.C., Bahar I., and Billiar T.R. Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies. Curr. Mol. Med. 4 (2004) 753-762
    • (2004) Curr. Mol. Med. , vol.4 , pp. 753-762
    • Vodovotz, Y.1    Kim, P.K.2    Bagci, E.Z.3    Ermentrout, G.B.4    Chow, C.C.5    Bahar, I.6    Billiar, T.R.7
  • 19
    • 0034693871 scopus 로고    scopus 로고
    • Janus kinases: components of multiple signaling pathways
    • Rane S.G., and Reddy E.P. Janus kinases: components of multiple signaling pathways. Oncogene 19 (2000) 5662-5679
    • (2000) Oncogene , vol.19 , pp. 5662-5679
    • Rane, S.G.1    Reddy, E.P.2
  • 20
    • 0347993913 scopus 로고    scopus 로고
    • Nitric oxide and superoxide in inflammation and immune regulation
    • Guzik T.J., Korbut R., and Adamek-Guzik T. Nitric oxide and superoxide in inflammation and immune regulation. J. Physiol. Pharmacol. 54 (2003) 469-487
    • (2003) J. Physiol. Pharmacol. , vol.54 , pp. 469-487
    • Guzik, T.J.1    Korbut, R.2    Adamek-Guzik, T.3
  • 21
    • 9644310524 scopus 로고    scopus 로고
    • Differential regulation of apoptotic cell death in senescent human cells
    • Hampel B., Malisan F., Niederegger H., Testi R., and Jansen-Durr P. Differential regulation of apoptotic cell death in senescent human cells. Exp. Gerontol. 39 (2004) 1713-1721
    • (2004) Exp. Gerontol. , vol.39 , pp. 1713-1721
    • Hampel, B.1    Malisan, F.2    Niederegger, H.3    Testi, R.4    Jansen-Durr, P.5
  • 22
    • 0036860951 scopus 로고    scopus 로고
    • Dose effect of oxidative stress on signal transduction in aging
    • Yoon S.O., Yun C.H., and Chung A.S. Dose effect of oxidative stress on signal transduction in aging. Mech. Ageing Dev. 123 (2002) 1597-1604
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 1597-1604
    • Yoon, S.O.1    Yun, C.H.2    Chung, A.S.3
  • 23
    • 11144303507 scopus 로고    scopus 로고
    • Reactive oxygen species and the mitochondrial signaling pathway of cell death
    • Le Bras M., Clement M.V., Pervaiz S., and Brenner C. Reactive oxygen species and the mitochondrial signaling pathway of cell death. Histol. Histopathol. 20 (2005) 205-219
    • (2005) Histol. Histopathol. , vol.20 , pp. 205-219
    • Le Bras, M.1    Clement, M.V.2    Pervaiz, S.3    Brenner, C.4
  • 24
    • 2942605828 scopus 로고    scopus 로고
    • The enhancing action of d-galactosamine on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells
    • Morikawa A., Koide N., Sugiyama T., Mu M.M., Hassan F., Islam S., et al. The enhancing action of d-galactosamine on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. FEMS Immunol. Med. Microbiol. 41 (2004) 211-218
    • (2004) FEMS Immunol. Med. Microbiol. , vol.41 , pp. 211-218
    • Morikawa, A.1    Koide, N.2    Sugiyama, T.3    Mu, M.M.4    Hassan, F.5    Islam, S.6
  • 25
    • 33745196888 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of mushroom Phellinus linteus in LPS-stimulated RAW264.7 macrophages
    • Kim B.C., Choi J.W., Hong H.Y., Lee S.A., Hong S., Park E.H., et al. Heme oxygenase-1 mediates the anti-inflammatory effect of mushroom Phellinus linteus in LPS-stimulated RAW264.7 macrophages. J. Ethnopharmacol. 106 (2006) 364-371
    • (2006) J. Ethnopharmacol. , vol.106 , pp. 364-371
    • Kim, B.C.1    Choi, J.W.2    Hong, H.Y.3    Lee, S.A.4    Hong, S.5    Park, E.H.6
  • 27
    • 33745596809 scopus 로고    scopus 로고
    • Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells
    • Collett G.P., and Campbell F.C. Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. Carcinogenesis 27 (2006) 1285-1291
    • (2006) Carcinogenesis , vol.27 , pp. 1285-1291
    • Collett, G.P.1    Campbell, F.C.2
  • 28
    • 22544482621 scopus 로고    scopus 로고
    • Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway
    • Kim H.S., and Lee M.S. Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway. Mol. Cell. Biol. 25 (2005) 6821-6833
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 6821-6833
    • Kim, H.S.1    Lee, M.S.2
  • 29
    • 0035902480 scopus 로고    scopus 로고
    • Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B
    • Ganster R.W., Taylor B.S., Shao L., and Geller D.A. Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B. Proc. Natl Acad. Sci. USA 98 (2001) 8638-8643
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 8638-8643
    • Ganster, R.W.1    Taylor, B.S.2    Shao, L.3    Geller, D.A.4
  • 30
    • 12744259191 scopus 로고    scopus 로고
    • IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability transition in the liver
    • El Assal O., Hong F., Kim W.H., Radaeva S., and Gao B. IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability transition in the liver. Cell Mol. Immunol. 1 (2004) 205-211
    • (2004) Cell Mol. Immunol. , vol.1 , pp. 205-211
    • El Assal, O.1    Hong, F.2    Kim, W.H.3    Radaeva, S.4    Gao, B.5
  • 31
    • 33645939916 scopus 로고    scopus 로고
    • Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer
    • Schottelius A.J., and Dinter H. Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer. Cancer Treat. Res. 130 (2006) 67-87
    • (2006) Cancer Treat. Res. , vol.130 , pp. 67-87
    • Schottelius, A.J.1    Dinter, H.2
  • 33
    • 0026453418 scopus 로고
    • Peroxynitrite formation from macrophage-derived nitric oxide
    • Ischiropoulos H., Zhu L., and Beckman J.S. Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298 (1992) 446-451
    • (1992) Arch. Biochem. Biophys. , vol.298 , pp. 446-451
    • Ischiropoulos, H.1    Zhu, L.2    Beckman, J.S.3
  • 34
    • 0035129270 scopus 로고    scopus 로고
    • Impaired response to interferon-gamma in activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide
    • Llovera M., Pearson J.D., Moreno C., and Riveros-Moreno V. Impaired response to interferon-gamma in activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide. Br. J. Pharmacol. 132 (2001) 419-426
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 419-426
    • Llovera, M.1    Pearson, J.D.2    Moreno, C.3    Riveros-Moreno, V.4
  • 35
    • 33745167654 scopus 로고    scopus 로고
    • The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas
    • Bernal-Mizrachi L., Lovly C.M., and Ratner L. The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas. Proc. Natl. Acad. Sci. USA 103 (2006) 9220-9225
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9220-9225
    • Bernal-Mizrachi, L.1    Lovly, C.M.2    Ratner, L.3
  • 36
    • 33646103893 scopus 로고    scopus 로고
    • Caspases leave the beaten track: caspase-mediated activation of NF-kappaB
    • Lamkanfi M., Declercq W., Vanden Berghe T., and Vandenabeele P. Caspases leave the beaten track: caspase-mediated activation of NF-kappaB. J. Cell Biol. 173 (2006) 165-171
    • (2006) J. Cell Biol. , vol.173 , pp. 165-171
    • Lamkanfi, M.1    Declercq, W.2    Vanden Berghe, T.3    Vandenabeele, P.4
  • 37
    • 0034672409 scopus 로고    scopus 로고
    • Cross-talk between interleukin 1β (IL-1β) and IL-6 signaling pathways: IL-1β selectively inhibits IL-6-activated signal transduced and activator of transcription factor 1 (STAT1) by a proteasome-dependent mechanism
    • Shen X., Tian Z., Holtzman M.J., and Gao B. Cross-talk between interleukin 1β (IL-1β) and IL-6 signaling pathways: IL-1β selectively inhibits IL-6-activated signal transduced and activator of transcription factor 1 (STAT1) by a proteasome-dependent mechanism. Biochem. J. 352 (2000) 913-919
    • (2000) Biochem. J. , vol.352 , pp. 913-919
    • Shen, X.1    Tian, Z.2    Holtzman, M.J.3    Gao, B.4
  • 38
    • 8944251628 scopus 로고    scopus 로고
    • A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells
    • Nakajima K., Yamanaka Y., Nakae K., Kojima H., Ichiba M., Kiuchi N., et al. A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J. 15 (1996) 3651-3658
    • (1996) EMBO J. , vol.15 , pp. 3651-3658
    • Nakajima, K.1    Yamanaka, Y.2    Nakae, K.3    Kojima, H.4    Ichiba, M.5    Kiuchi, N.6
  • 39
    • 24344453811 scopus 로고    scopus 로고
    • Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway
    • Kim W.H., Lee J.W., Gao B., and Jung M.H. Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway. Cell Signal. 17 (2005) 1516-1532
    • (2005) Cell Signal. , vol.17 , pp. 1516-1532
    • Kim, W.H.1    Lee, J.W.2    Gao, B.3    Jung, M.H.4
  • 40
    • 0041695625 scopus 로고    scopus 로고
    • Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes
    • Tunon M.J., Sanchez-Campos S., Gutierrez B., Culebras J.M., and Gonzalez-Gallego J. Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes. Biochem. Pharmacol. 66 (2003) 439-445
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 439-445
    • Tunon, M.J.1    Sanchez-Campos, S.2    Gutierrez, B.3    Culebras, J.M.4    Gonzalez-Gallego, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.