-
1
-
-
0021063273
-
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
-
Schwab M, Alitalo K, Klempnauer KH, Varmus HE, Bishop JM, Gilbert F, et al. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature 1983;305:245-8. (Pubitemid 14227614)
-
(1983)
Nature
, vol.305
, Issue.5931
, pp. 245-248
-
-
Schwab, M.1
Alitalo, K.2
Klempnauer, K.H.3
-
2
-
-
0021047844
-
Transposition and amplification of oncogene-related sequences in human neuroblastomas
-
Kohl NE, Kanda N, Schreck RR, Bruns G, Latt SA, Gilbert F, et al. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell 1983;35:359-67. (Pubitemid 14202914)
-
(1983)
Cell
, vol.35
, Issue.2 I
, pp. 359-367
-
-
Kohl, N.E.1
Kanda, N.2
Schreck, R.R.3
-
3
-
-
0029686266
-
Proteins of the Myc network: Essential regulators of cell growth and differentiation
-
Henriksson M, Luscher B. Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res 1996; 68:109-82.
-
(1996)
Adv Cancer Res
, vol.68
, pp. 109-182
-
-
Henriksson, M.1
Luscher, B.2
-
4
-
-
0022650216
-
Differential expression of myc family genes during murine development
-
Zimmerman KA, Yancopoulos GD, Collum RG, Smith RK, Kohl NE, Denis KA, et al. Differential expression of myc family genes during murine development. Nature 1986;319:780-3. (Pubitemid 16145034)
-
(1986)
Nature
, vol.319
, Issue.6056
, pp. 780-783
-
-
Zimmerman, K.A.1
Yancopoulos, G.D.2
Collum, R.G.3
-
5
-
-
0022392771
-
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer
-
DOI 10.1038/318069a0
-
Nau MM, Brooks BJ, Battey J, Sausville E, Gazdar AF, Kirsch IR, et al. L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature 1985;318:69-73. (Pubitemid 16230338)
-
(1985)
Nature
, vol.318
, Issue.6041
, pp. 69-73
-
-
Nau, M.M.1
Brooks, B.J.2
Battey, J.3
-
6
-
-
0027080193
-
Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene
-
Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, et al. Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev 1992;6:2248-57. (Pubitemid 23037391)
-
(1992)
Genes and Development
, vol.6
, Issue.12 A
, pp. 2248-2257
-
-
Charron, J.1
Malynn, B.A.2
Fisher, P.3
Stewart, V.4
Jeannotte, L.5
Goff, S.P.6
Robertson, E.J.7
Alt, F.W.8
-
7
-
-
0027312135
-
Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse
-
Sawai S, Shimono A, Wakamatsu Y, Palmes C, Hanaoka K, Kondoh H. Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse. Development 1993; 117:1445-55. (Pubitemid 23154508)
-
(1993)
Development
, vol.117
, Issue.4
, pp. 1445-1455
-
-
Sawai, S.1
Shimono, A.2
Wakamatsu, Y.3
Palmes, C.4
Hanaoka, K.5
Kondoh, H.6
-
8
-
-
0034213414
-
N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
-
Malynn BA, de Alboran IM, O'Hagan RC, Bronson R, Davidson L, DePinho RA, et al. N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation. Genes Dev 2000; 14:1390-9. (Pubitemid 30397082)
-
(2000)
Genes and Development
, vol.14
, Issue.11
, pp. 1390-1399
-
-
Malynn, B.A.1
De Alboran, I.M.2
O'Hagan, R.C.3
Bronson, R.4
Davidson, L.5
DePinho, R.A.6
Alt, F.W.7
-
9
-
-
0027066738
-
Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop
-
Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev 1992;6:2235-47. (Pubitemid 23037390)
-
(1992)
Genes and Development
, vol.6
, Issue.12 A
, pp. 2235-2247
-
-
Stanton, B.R.1
Perkins, A.S.2
Tessarollo, L.3
Sassoon, D.A.4
Parada, L.F.5
-
10
-
-
0037108268
-
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
-
Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 2002; 16:2699-712.
-
(2002)
Genes Dev
, vol.16
, pp. 2699-2712
-
-
Knoepfler, P.S.1
Cheng, P.F.2
Eisenman, R.N.3
-
11
-
-
84861399134
-
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC
-
Swartling FJ, Savov V, Persson AI, Chen J, Hackett CS, Northcott PA, et al. Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell 2012;21:601-13.
-
(2012)
Cancer Cell
, vol.21
, pp. 601-613
-
-
Swartling, F.J.1
Savov, V.2
Persson, A.I.3
Chen, J.4
Hackett, C.S.5
Northcott, P.A.6
-
12
-
-
20944433656
-
MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome
-
DOI 10.1038/ng1546
-
van Bokhoven H, Celli J, van Reeuwijk J, Rinne T, Glaudemans B, van Beusekom E, et al. MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome. Nat Genet 2005;37:465-7. (Pubitemid 40617272)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 465-467
-
-
Van Bokhoven, H.1
Celli, J.2
Van Reeuwijk, J.3
Rinne, T.4
Glaudemans, B.5
Van Beusekom, E.6
Rieu, P.7
Newbury-Ecob, R.A.8
Chiang, C.9
Brunner, H.G.10
-
13
-
-
0022388606
-
Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
-
Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-6. (Pubitemid 16216827)
-
(1985)
New England Journal of Medicine
, vol.313
, Issue.18
, pp. 1111-1116
-
-
Seeger, R.C.1
Brodeur, G.M.2
Sather, H.3
-
14
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 1984;224:1121-4. (Pubitemid 14106392)
-
(1984)
Science
, vol.224
, Issue.4653
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
-
15
-
-
0025979843
-
Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A Pediatric Oncology Group study
-
Look AT, Hayes FA, Shuster JJ, Douglass EC, Castleberry RP, Bowman LC, et al. Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 1991;9:581-91.
-
(1991)
J Clin Oncol
, vol.9
, pp. 581-591
-
-
Look, A.T.1
Hayes, F.A.2
Shuster, J.J.3
Douglass, E.C.4
Castleberry, R.P.5
Bowman, L.C.6
-
16
-
-
0031014625
-
MYCN oncogene amplification in neuroblastoma is associated with worse prognosis, except in stage 4s: The Italian experience with 295 children
-
Tonini GP, Boni L, Pession A, Rogers D, Iolascon A, Basso G, et al. MYCN oncogene amplification in neuroblastoma is associated with worse prognosis, except in stage 4s: the Italian experience with 295 children. J Clin Oncol 1997;15:85-93. (Pubitemid 27020561)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.1
, pp. 85-93
-
-
Tonini, G.P.1
Boni, L.2
Pession, A.3
Rogers, D.4
Lolascon, A.5
Basso, G.6
Cordero, D.M.L.7
Casale, F.8
Pession, A.9
Perri, P.10
Mazzocco, K.11
Scaruffi, P.12
Lo, C.C.13
Marchese, N.14
Milanaccio, C.15
Conte, M.16
Bruzzi, P.17
De Bernardi, B.18
-
17
-
-
39749177356
-
Clinical significance of MYCN amplification and ploidy in favorable-stage neuroblastoma: A report from the Children's Oncology Group
-
DOI 10.1200/JCO.2007.13.9493
-
Schneiderman J, London WB, Brodeur GM, Castleberry RP, Look AT, Cohn SL. Clinical significance of MYCN amplification and ploidy in favorable-stage neuroblastoma: a report from the Children's Oncology Group. J Clin Oncol 2008;26:913-8. (Pubitemid 351398084)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.6
, pp. 913-918
-
-
Schneiderman, J.1
London, W.B.2
Brodeur, G.M.3
Castleberry, R.P.4
Look, A.T.5
Cohn, S.L.6
-
18
-
-
0842309106
-
MYCN in neuronal tumours
-
DOI 10.1016/S0304-3835(03)00454-3
-
Schwab M. MYCN in neuronal tumours. Cancer Lett 2004;204: 179-87. (Pubitemid 38167721)
-
(2004)
Cancer Letters
, vol.204
, Issue.2
, pp. 179-187
-
-
Schwab, M.1
-
19
-
-
77952375097
-
Pleiotropic role for MYCN in medulloblastoma
-
Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, et al. Pleiotropic role for MYCN in medulloblastoma. Genes Dev 2010;24:1059-72.
-
(2010)
Genes Dev
, vol.24
, pp. 1059-1072
-
-
Swartling, F.J.1
Grimmer, M.R.2
Hackett, C.S.3
Northcott, P.A.4
Fan, Q.W.5
Goldenberg, D.D.6
-
20
-
-
63749118521
-
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
-
Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, et al. Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol 2009;27:1627-36.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1627-1636
-
-
Pfister, S.1
Remke, M.2
Benner, A.3
Mendrzyk, F.4
Toedt, G.5
Felsberg, J.6
-
21
-
-
33645094926
-
N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medullo-blastoma
-
Browd SR, Kenney AM, Gottfried ON, Yoon JW, Walterhouse D, Pedone CA, et al. N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medullo-blastoma. Cancer Res 2006;66:2666-72.
-
(2006)
Cancer Res
, vol.66
, pp. 2666-2672
-
-
Browd, S.R.1
Kenney, A.M.2
Gottfried, O.N.3
Yoon, J.W.4
Walterhouse, D.5
Pedone, C.A.6
-
22
-
-
0034998193
-
Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization
-
Hui AB, Lo KW, Yin XL, Poon WS, Ng HK. Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization. Lab Invest 2001;81:717-23. (Pubitemid 32466534)
-
(2001)
Laboratory Investigation
, vol.81
, Issue.5
, pp. 717-723
-
-
Hui, A.B.-Y.1
Lo, K.-W.2
Yin, X.-L.3
Poon, W.-S.4
Ng, H.-K.5
-
23
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis PW, Muller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, et al. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 2013;340:857-61.
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Muller, M.M.2
Koletsky, M.S.3
Cordero, F.4
Lin, S.5
Banaszynski, L.A.6
-
24
-
-
84877621282
-
Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN
-
Bjerke L, Mackay A, Nandhabalan M, Burford A, Jury A, Popov S, et al. Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN. Cancer Discov 2013;3:512-9.
-
(2013)
Cancer Discov
, vol.3
, pp. 512-519
-
-
Bjerke, L.1
Mackay, A.2
Nandhabalan, M.3
Burford, A.4
Jury, A.5
Popov, S.6
-
25
-
-
0021241701
-
Expression and amplification of the N-myc gene in primary retinoblastoma
-
Lee WH, Murphree AL, Benedict WF. Expression and amplification of the N-myc gene in primary retinoblastoma. Nature 1984;309:458-60. (Pubitemid 14102451)
-
(1984)
Nature
, vol.309
, Issue.5967
, pp. 458-460
-
-
Lee, W.-H.1
Murphree, A.L.2
Benedict, W.F.3
-
26
-
-
47549116530
-
N-myc amplification was rarely detected by fluorescence in situ hybridization in retinoblastoma
-
Kim JH, Choi JM, Yu YS, Kim DH, Kim KW. N-myc amplification was rarely detected by fluorescence in situ hybridization in retinoblastoma. Hum Pathol 2008;39:1172-5.
-
(2008)
Hum Pathol
, vol.39
, pp. 1172-1175
-
-
Kim, J.H.1
Choi, J.M.2
Yu, Y.S.3
Kim, D.H.4
Kim, K.W.5
-
27
-
-
33847003995
-
Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification
-
MacPherson D, Conkrite K, Tam M, Mukai S, Mu D, Jacks T. Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification. EMBO J 2007;26:784-94.
-
(2007)
EMBO J
, vol.26
, pp. 784-794
-
-
MacPherson, D.1
Conkrite, K.2
Tam, M.3
Mukai, S.4
Mu, D.5
Jacks, T.6
-
28
-
-
84875810807
-
Characterisation of retinoblastomas without RB1 mutations: Genomic, gene expression, and clinical studies
-
Rushlow DE, Mol BM, Kennett JY, Yee S, Pajovic S, Thériault BL, et al. Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies. Lancet Oncol 2013;14:327-34.
-
(2013)
Lancet Oncol
, vol.14
, pp. 327-334
-
-
Rushlow, D.E.1
Mol, B.M.2
Kennett, J.Y.3
Yee, S.4
Pajovic, S.5
Thériault, B.L.6
-
29
-
-
0022498263
-
Tumour induction by the retinoblastoma mutation is independent of N-myc expression
-
Squire J, Goddard AD, Canton M, Becker A, Phillips RA, Gallie BL. Tumour induction by the retinoblastoma mutation is independent of N-myc expression. Nature 1986;322:555-7. (Pubitemid 16049207)
-
(1986)
Nature
, vol.322
, Issue.6079
, pp. 555-557
-
-
Squire, J.1
Goddard, A.D.2
Canton, M.3
-
30
-
-
0028353848
-
MYCN gene amplification in rhabdomyosarcoma
-
Driman D, Thorner PS, Greenberg ML, Chilton-MacNeill S, Squire J. MYCN gene amplification in rhabdomyosarcoma. Cancer 1994;73:2231-7. (Pubitemid 24107982)
-
(1994)
Cancer
, vol.73
, Issue.8
, pp. 2231-2237
-
-
Driman, D.1
Thorner, P.S.2
Greenberg, M.L.3
Chilton-MacNeill, S.4
Squire, J.5
-
31
-
-
33644866331
-
MYCN deregulation as a potential target for novel therapies in rhabdomyosarcoma
-
DOI 10.1586/14737140.6.2.217
-
Morgenstern DA, Anderson J. MYCN deregulation as a potential target for novel therapies in rhabdomyosarcoma. Expert Rev Anticancer Ther 2006;6:217-24. (Pubitemid 44192933)
-
(2006)
Expert Review of Anticancer Therapy
, vol.6
, Issue.2
, pp. 217-224
-
-
Morgenstern, D.A.1
Anderson, J.2
-
32
-
-
0009483251
-
Human small-cell lung cancers show amplification and expression of the N-myc gene
-
Nau MM, Brooks BJ Jr, Carney DN, Gazdar AF, Battey JF, Sausville EA, et al. Human small-cell lung cancers show amplification and expression of the N-myc gene. Proc Natl Acad Sci U S A 1986;83:1092-6. (Pubitemid 16086418)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.4
, pp. 1092-1096
-
-
Nau, M.M.1
Brooks, J.B.J.2
Carney, D.N.3
-
33
-
-
0022462112
-
Gene amplification of c-myc and N-myc in small cell carcinoma of the lung
-
Wong AJ, Ruppert JM, Eggleston J, Hamilton SR, Baylin SB, Vogelstein B. Geneamplification of c-myc and N-myc in small cell carcinoma of the lung. Science 1986;233:461-4. (Pubitemid 16046305)
-
(1986)
Science
, vol.233
, Issue.4762
, pp. 461-464
-
-
Wong, A.J.1
Ruppert, J.M.2
Eggleston, J.3
-
34
-
-
0023263664
-
Increased expression of N-myc in human small cell lung cancer biopsies predicts lack of response to chemotherapy and poor prognosis
-
Funa K, Steinholtz L, Nou E, Bergh J. Increased expression of N-myc in human small cell lung cancer biopsies predicts lack of response to chemotherapy and poor prognosis. Am J Clin Pathol 1987;88:216-20. (Pubitemid 17137873)
-
(1987)
American Journal of Clinical Pathology
, vol.88
, Issue.2
, pp. 216-220
-
-
Funa, K.1
Steinholtz, L.2
Nou, E.3
Bergh, J.4
-
35
-
-
84860168795
-
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
-
Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, et al. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov 2011;1:487-95.
-
(2011)
Cancer Discov
, vol.1
, pp. 487-495
-
-
Beltran, H.1
Rickman, D.S.2
Park, K.3
Chae, S.S.4
Sboner, A.5
MacDonald, T.Y.6
-
36
-
-
84873048485
-
Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer
-
Mosquera JM, Beltran H, Park K, MacDonald TY, Robinson BD, Tagawa ST, et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia 2013;15:1-10.
-
(2013)
Neoplasia
, vol.15
, pp. 1-10
-
-
Mosquera, J.M.1
Beltran, H.2
Park, K.3
MacDonald, T.Y.4
Robinson, B.D.5
Tagawa, S.T.6
-
37
-
-
0029555045
-
N-myc protein expression in human breast carcinoma: Prognostic implications
-
Mizukami Y, Nonomura A, Takizawa T, Noguchi M, Michigishi T, Nakamura S, et al. N-myc protein expression in human breast carcinoma: prognostic implications. Anticancer Res 1995;15:2899-905. (Pubitemid 26095120)
-
(1995)
Anticancer Research
, vol.15
, Issue.6 B
, pp. 2899-2905
-
-
Mizukami, Y.1
Nonomura, A.2
Takizawa, T.3
Noguchi, M.4
Michigishi, T.5
Nakamura, S.6
Ishizaki, T.7
-
38
-
-
55649123695
-
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
-
Westermann F, Muth D, Benner A, Bauer T, Henrich KO, Oberthuer A, et al. Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 2008;9:R150.
-
(2008)
Genome Biol
, vol.9
-
-
Westermann, F.1
Muth, D.2
Benner, A.3
Bauer, T.4
Henrich, K.O.5
Oberthuer, A.6
-
39
-
-
0031727309
-
Prognostic significance of MYCN oncogene expression in childhood neuroblastoma
-
Bordow SB, Norris MD, Haber PS, Marshall GM, Haber M. Prognostic significance of MYCN oncogene expression in childhood neuroblastoma. J Clin Oncol 1998;16:3286-94. (Pubitemid 28481623)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.10
, pp. 3286-3294
-
-
Bordow, S.B.1
Norris, M.D.2
Haber, P.S.3
Marshall, G.M.4
Haber, M.5
-
40
-
-
0006498730
-
N-myc can cooperate with ras to transform normal cells in culture
-
DOI 10.1073/pnas.82.16.5455
-
Yancopoulos GD, Nisen PD, Tesfaye A, Kohl NE, Goldfarb MP, Alt FW. N-myc can cooperate with ras to transform normal cells in culture. Proc Natl Acad Sci U S A 1985;82:5455-9. (Pubitemid 15012123)
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, Issue.16
, pp. 5455-5459
-
-
Yancopoulos, G.D.1
Nisen, P.D.2
Tesfaye, A.3
-
41
-
-
0030999641
-
Targeted expression of MYCN causes neuroblastoma in transgenic mice
-
DOI 10.1093/emboj/16.11.2985
-
Weiss WA, Aldape K, Mohapatra G, Feuerstein BG, Bishop JM. Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J 1997;16:2985-95. (Pubitemid 27234938)
-
(1997)
EMBO Journal
, vol.16
, Issue.11
, pp. 2985-2995
-
-
Weiss, W.A.1
Aldape, K.2
Mohapatra, G.3
Feuerstein, B.G.4
Bishop, J.M.5
-
42
-
-
0031004652
-
Modulation of N-myc expression alters the invasiveness of neuroblastoma
-
DOI 10.1023/A:1018448710006
-
Goodman LA, Liu BC, Thiele CJ, Schmidt ML, Cohn SL, Yamashiro JM, et al. Modulation of N-myc expression alters the invasiveness of neuroblastoma. Clin Exp Metastasis 1997;15:130-9. (Pubitemid 27157815)
-
(1997)
Clinical and Experimental Metastasis
, vol.15
, Issue.2
, pp. 130-139
-
-
Goodman, L.A.1
Liu, B.C.S.2
Thiele, C.J.3
Schmidt, M.L.4
Cohn, S.L.5
Yamashiro, J.M.6
Pai, D.S.M.7
Ikegaki, N.8
Wada, R.K.9
-
43
-
-
0021800964
-
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
-
DOI 10.1038/316160a0
-
Schwab M, Varmus HE, Bishop JM. Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature 1985;316:160-2. (Pubitemid 15073682)
-
(1985)
Nature
, vol.316
, Issue.6024
, pp. 160-162
-
-
Schwab, M.1
Varmus, H.E.2
Bishop, J.M.3
-
44
-
-
20444438759
-
Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest
-
DOI 10.1158/1078-0432.CCR-04-2071
-
Yaari S, Jacob-Hirsch J, Amariglio N, Haklai R, Rechavi G, Kloog Y. Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest. Clin Cancer Res 2005;11:4321-30. (Pubitemid 40825619)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.12
, pp. 4321-4330
-
-
Yaari, S.1
Jacob-Hirsch, J.2
Amariglio, N.3
Haklai, R.4
Rechavi, G.5
Kloog, Y.6
-
45
-
-
0029743372
-
Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
-
Lutz W, Stohr M, Schurmann J, Wenzel A, Lohr A, Schwab M. Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996;13:803-12. (Pubitemid 26312908)
-
(1996)
Oncogene
, vol.13
, Issue.4
, pp. 803-812
-
-
Lutz, W.1
Stohr, M.2
Schurmann, J.3
Wenzel, A.4
Lohr, A.5
Schwab, M.6
-
46
-
-
79959703462
-
Stable knockdown of MYCN by lentivirus-based RNAi inhibits human neuroblastoma cells growth in vitro and in vivo
-
Jiang R, Xue S, Jin Z. Stable knockdown of MYCN by lentivirus-based RNAi inhibits human neuroblastoma cells growth in vitro and in vivo. Biochem Biophys Res Commun 2011;410:364-70.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 364-370
-
-
Jiang, R.1
Xue, S.2
Jin, Z.3
-
47
-
-
0032523759
-
Myc activation reduces fibroblast clonogenicity via an apoptotic mechanism that can be suppressed by a soluble paracrine factor
-
DOI 10.1016/S0304-3835(98)00045-7, PII S0304383598000457
-
Rupnow BA, Murtha AD, Chen E, Knox SJ. Myc activation reduces fibroblast clonogenicity via an apoptotic mechanism that can be suppressed by a soluble paracrine factor. Cancer Lett 1998;127:211-9. (Pubitemid 28230806)
-
(1998)
Cancer Letters
, vol.127
, Issue.1-2
, pp. 211-219
-
-
Rupnow, B.A.1
Murtha, A.D.2
Chen, E.3
Knox, S.J.4
-
48
-
-
0025763419
-
Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with myc
-
Blackwood EM, Eisenman RN. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991;251:1211-7. (Pubitemid 21926213)
-
(1991)
Science
, vol.251
, Issue.4998
, pp. 1211-1217
-
-
Blackwood, E.M.1
Eisenman, R.N.2
-
49
-
-
0025990074
-
The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells
-
Wenzel A, Cziepluch C, Hamann U, Schurmann J, Schwab M. The NMyc oncoprotein is associated in vivo with the phosphoprotein Max (p20/22) in human neuroblastoma cells. EMBO J 1991;10:3703-12. (Pubitemid 21905397)
-
(1991)
EMBO Journal
, vol.10
, Issue.12
, pp. 3703-3712
-
-
Wenzel, A.1
Cziepluch, C.2
Hamann, U.3
Schurmann, J.4
Schwab, M.5
-
50
-
-
77949524622
-
Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation
-
Murphy DM, Buckley PG, Bryan K, Das S, Alcock L, Foley NH, et al. Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation. PLoS One 2009;4:e8154.
-
(2009)
PLoS One
, vol.4
-
-
Murphy, D.M.1
Buckley, P.G.2
Bryan, K.3
Das, S.4
Alcock, L.5
Foley, N.H.6
-
51
-
-
33745558509
-
Myc influences global chromatin structure
-
DOI 10.1038/sj.emboj.7601152, PII 7601152
-
Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Myc influences global chromatin structure. EMBO J 2006; 25:2723-34. (Pubitemid 43980380)
-
(2006)
EMBO Journal
, vol.25
, Issue.12
, pp. 2723-2734
-
-
Knoepfler, P.S.1
Zhang, X.-Y.2
Cheng, P.F.3
Gafken, P.R.4
McMahon, S.B.5
Eisenman, R.N.6
-
52
-
-
0034744956
-
INK4b
-
DOI 10.1038/35070086
-
Seoane J, Pouponnot C, Staller P, Schader M, Eilers M, Massague J. TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b. Nat Cell Biol 2001;3:400-8. (Pubitemid 32288448)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.4
, pp. 400-408
-
-
Seoane, J.1
Pouponnot, C.2
Staller, P.3
Schader, M.4
Eilers, M.5
Massague, J.6
-
53
-
-
13444270415
-
Myc represses transcription through recruitment of DNA methyltransferase corepressor
-
DOI 10.1038/sj.emboj.7600509
-
Brenner C, Deplus R, Didelot C, Loriot A, Viré E, De Smet C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005;24:336-46. (Pubitemid 40216138)
-
(2005)
EMBO Journal
, vol.24
, Issue.2
, pp. 336-346
-
-
Brenner, C.1
Deplus, R.2
Didelot, C.3
Loriot, A.4
Vire, E.5
De Smet, C.6
Gutierrez, A.7
Danovi, D.8
Bernard, D.9
Boon, T.10
Pelicci, P.G.11
Amati, B.12
Kouzarides, T.13
De Launoit, Y.14
Di, C.L.15
Fuks, F.16
-
54
-
-
84875415642
-
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: Functional and therapeutic implications
-
Corvetta D, Chayka O, Gherardi S, D'Acunto CW, Cantilena S, Valli E, et al. Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. J Biol Chem 2013;288:8332-41.
-
(2013)
J Biol Chem
, vol.288
, pp. 8332-8341
-
-
Corvetta, D.1
Chayka, O.2
Gherardi, S.3
D'Acunto, C.W.4
Cantilena, S.5
Valli, E.6
-
55
-
-
0043092201
-
Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma
-
Alaminos M, Mora J, Cheung NK, Smith A, Qin J, Chen L, et al. Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma. Cancer Res 2003;63:4538-46. (Pubitemid 36951027)
-
(2003)
Cancer Research
, vol.63
, Issue.15
, pp. 4538-4546
-
-
Alaminos, M.1
Mora, J.2
Cheung, N.-K.V.3
Smith, A.4
Qin, J.5
Chen, L.6
Gerald, W.L.7
-
56
-
-
84863013857
-
Modeling a lethal prostate cancer variant with small-cell carcinoma features
-
Tzelepi V, Zhang J, Lu JF, Kleb B, Wu G, Wan X, et al. Modeling a lethal prostate cancer variant with small-cell carcinoma features. Clin Cancer Res 2012;18:666-77.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 666-677
-
-
Tzelepi, V.1
Zhang, J.2
Lu, J.F.3
Kleb, B.4
Wu, G.5
Wan, X.6
-
57
-
-
67149099142
-
N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b
-
Cotterman R, Knoepfler PS. N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b. PLoS One 2009;4:e5799.
-
(2009)
PLoS One
, vol.4
-
-
Cotterman, R.1
Knoepfler, P.S.2
-
58
-
-
77952240403
-
Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma
-
Ochiai H, Takenobu H, Nakagawa A, Yamaguchi Y, Kimura M, Ohira M, et al. Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma. Oncogene 2010;29:2681-90.
-
(2010)
Oncogene
, vol.29
, pp. 2681-2690
-
-
Ochiai, H.1
Takenobu, H.2
Nakagawa, A.3
Yamaguchi, Y.4
Kimura, M.5
Ohira, M.6
-
59
-
-
17744400301
-
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
-
DOI 10.1093/emboj/20.6.1383
-
Boon K, Caron HN, van Asperen R, Valentijn L, Hermus M-C, van Sluis P, et al. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 2001;20:1383-93. (Pubitemid 32233978)
-
(2001)
EMBO Journal
, vol.20
, Issue.6
, pp. 1383-1393
-
-
Boon, K.1
Caron, H.N.2
Van Asperen, R.3
Valentijn, L.4
Hermus, M.-C.5
Van Sluis, P.6
Roobeek, I.7
Weis, I.8
Voute, P.A.9
Schwab, M.10
Versteeg, R.11
-
60
-
-
14144250455
-
The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma
-
DOI 10.1073/pnas.0405495102
-
Slack A, Chen Z, Tonelli R, Pule M, Hunt L, Pession A, et al. The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc Natl Acad Sci U S A 2005;102:731-6. (Pubitemid 40282734)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 731-736
-
-
Slack, A.1
Chen, Z.2
Tonelli, R.3
Pule, M.4
Hunt, L.5
Pession, A.6
Shohet, J.M.7
-
61
-
-
84891694008
-
p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance
-
Chen L, Tweddle DA. p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance. Front Oncol 2012;2:173.
-
(2012)
Front Oncol
, vol.2
, pp. 173
-
-
Chen, L.1
Tweddle, D.A.2
-
62
-
-
53649092492
-
N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma
-
Hossain MS, Ozaki T, Wang H, Nakagawa A, Takenobu H, Ohira M, et al. N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma. Oncogene 2008;27:6075-82.
-
(2008)
Oncogene
, vol.27
, pp. 6075-6082
-
-
Hossain, M.S.1
Ozaki, T.2
Wang, H.3
Nakagawa, A.4
Takenobu, H.5
Ohira, M.6
-
63
-
-
19044380776
-
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma
-
DOI 10.1016/S1535-6108(02)00179-4
-
Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, et al. Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell 2002;2:377-86. (Pubitemid 41039104)
-
(2002)
Cancer Cell
, vol.2
, Issue.5
, pp. 377-386
-
-
Berwanger, B.1
Hartmann, O.2
Bergmann, E.3
Bernard, S.4
Nielsen, D.5
Krause, M.6
Kartal, A.7
Flynn, D.8
Wiedemeyer, R.9
Schwab, M.10
Schafer, H.11
Christiansen, H.12
Eilers, M.13
-
64
-
-
84869779376
-
Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification
-
Valentijn LJ, Koster J, Haneveld F, Aissa RA, van Sluis P, Broekmans ME, et al. Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification. Proc Natl Acad Sci U S A 2012;109:19190-5.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19190-19195
-
-
Valentijn, L.J.1
Koster, J.2
Haneveld, F.3
Aissa, R.A.4
Van Sluis, P.5
Broekmans, M.E.6
-
65
-
-
0034609818
-
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
-
Lasorella A, Noseda M, Beyna M, Yokota Y, Iavarone A. Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 2000;407:592-8.
-
(2000)
Nature
, vol.407
, pp. 592-598
-
-
Lasorella, A.1
Noseda, M.2
Beyna, M.3
Yokota, Y.4
Iavarone, A.5
-
66
-
-
0036373101
-
N-myc oncogene overexpression down-regulates leukemia inhibitory factor in neuroblastoma
-
DOI 10.1046/j.1432-1033.2002.03066.x
-
Hatzi E, Murphy C, Zoephel A, Ahorn H, Tontsch U, Bamberger AM, et al. N-myc oncogene overexpression down-regulates leukemia inhibitory factor in neuroblastoma. Eur J Biochem 2002;269:3732-41. (Pubitemid 34989122)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.15
, pp. 3732-3741
-
-
Hatzi, E.1
Murphy, C.2
Zoephel, A.3
Ahorn, H.4
Tontsch, U.5
Bamberger, A.-M.6
Yamauchi-Takihara, K.7
Schweigerer, L.8
Fotsis, T.9
-
67
-
-
84867659168
-
N-myc and noncoding RNAs in neuroblastoma
-
Buechner J, Einvik C. N-myc and noncoding RNAs in neuroblastoma. Mol Cancer Res 2012;10:1243-53.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 1243-1253
-
-
Buechner, J.1
Einvik, C.2
-
68
-
-
77955439834
-
Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
-
Schulte JH, Marschall T, Martin M, Rosenstiel P, Mestdagh P, Schlierf S, et al. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic Acids Res 2010;38:5919-28.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5919-5928
-
-
Schulte, J.H.1
Marschall, T.2
Martin, M.3
Rosenstiel, P.4
Mestdagh, P.5
Schlierf, S.6
-
69
-
-
57849107571
-
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
-
Otto T, Horn S, Brockmann M, Eilers U, Schüttrumpf L, Popov N, et al. Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell 2009;15:67-78.
-
(2009)
Cancer Cell
, vol.15
, pp. 67-78
-
-
Otto, T.1
Horn, S.2
Brockmann, M.3
Eilers, U.4
Schüttrumpf, L.5
Popov, N.6
-
70
-
-
24144441250
-
The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors
-
DOI 10.1016/j.devcel.2005.07.014, PII S1534580705002947
-
Sjostrom SK, Finn G, Hahn WC, Rowitch DH, Kenney AM. The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors. Dev Cell 2005;9:327-38. (Pubitemid 41235803)
-
(2005)
Developmental Cell
, vol.9
, Issue.3
, pp. 327-338
-
-
Sjostrom, S.K.1
Finn, G.2
Hahn, W.C.3
Rowitch, D.H.4
Kenney, A.M.5
-
71
-
-
1642474000
-
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors
-
DOI 10.1242/dev.00891
-
Kenney AM, Widlund HR, Rowitch DH. Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development 2004;131:217-28. (Pubitemid 38111428)
-
(2004)
Development
, vol.131
, Issue.1
, pp. 217-228
-
-
Kenney, A.M.1
Widlund, H.R.2
Rowitch, D.H.3
-
72
-
-
33748068792
-
Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma
-
DOI 10.1158/0008-5472.CAN-05-2769
-
Chesler L, Schlieve C, Goldenberg DD, Kenney A, Kim G, McMillan A, et al. Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma. Cancer Res 2006;66:8139-46. (Pubitemid 44299181)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8139-8146
-
-
Chesler, L.1
Schlieve, C.2
Goldenberg, D.D.3
Kenney, A.4
Kim, G.5
McMillan, A.6
Matthay, K.K.7
Rowitch, D.8
Weiss, W.A.9
-
73
-
-
84855183683
-
Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo
-
Segerstrom L, Baryawno N, Sveinbjornsson B, Wickström M, Elfman L, Kogner P, et al. Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo. Int J Cancer 2011;129:2958-65.
-
(2011)
Int J Cancer
, vol.129
, pp. 2958-2965
-
-
Segerstrom, L.1
Baryawno, N.2
Sveinbjornsson, B.3
Wickström, M.4
Elfman, L.5
Kogner, P.6
-
74
-
-
80055092081
-
Differential regulation of N-Myc and c-Myc synthesis, degradation, and transcriptional activity by the Ras/mitogenactivated protein kinase pathway
-
Kapeli K, Hurlin PJ. Differential regulation of N-Myc and c-Myc synthesis, degradation, and transcriptional activity by the Ras/mitogenactivated protein kinase pathway. J Biol Chem 2011;286:38498-508.
-
(2011)
J Biol Chem
, vol.286
, pp. 38498-38508
-
-
Kapeli, K.1
Hurlin, P.J.2
-
75
-
-
68049117231
-
MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: Potential implications for immune based therapy of human solid tumors
-
Xu H, Cheung IY, Guo HF, Cheung NK. MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors. Cancer Res 2009;69:6275-81.
-
(2009)
Cancer Res
, vol.69
, pp. 6275-6281
-
-
Xu, H.1
Cheung, I.Y.2
Guo, H.F.3
Cheung, N.K.4
-
76
-
-
79960211493
-
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
-
Buechner J, Tomte E, Haug BH, Henriksen JR, Løkke C, Flægstad T, et al. Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma. Br J Cancer 2011;105:296-303.
-
(2011)
Br J Cancer
, vol.105
, pp. 296-303
-
-
Buechner, J.1
Tomte, E.2
Haug, B.H.3
Henriksen, J.R.4
Løkke, C.5
Flægstad, T.6
-
77
-
-
77956277959
-
Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure
-
Storlazzi CT, Lonoce A, Guastadisegni MC, Trombetta D, D'Addabbo P, Daniele G, et al. Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure. Genome Res 2010;20:1198-206.
-
(2010)
Genome Res
, vol.20
, pp. 1198-1206
-
-
Storlazzi, C.T.1
Lonoce, A.2
Guastadisegni, M.C.3
Trombetta, D.4
D'Addabbo, P.5
Daniele, G.6
-
78
-
-
0029923488
-
Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma
-
George RE, Kenyon RM, McGuckin AG, Malcolm AJ, Pearson AD, Lunec J. Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma. United Kingdom Children's Cancer Study Group. Oncogene 1996;12:1583-7. (Pubitemid 26132046)
-
(1996)
Oncogene
, vol.12
, Issue.7
, pp. 1583-1587
-
-
George, R.E.1
Kenyon, R.M.2
McGuckin, A.G.3
Malcolm, A.J.4
Pearson, A.D.J.5
Lunec, J.6
-
79
-
-
54049149961
-
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
-
Janoueix-Lerosey I, Lequin D, Brugieres L, Ribeiro A, de Pontual L, Combaret V, et al. Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature 2008;455:967-70.
-
(2008)
Nature
, vol.455
, pp. 967-970
-
-
Janoueix-Lerosey, I.1
Lequin, D.2
Brugieres, L.3
Ribeiro, A.4
De Pontual, L.5
Combaret, V.6
-
80
-
-
0027743434
-
Detection of N-myc gene amplification by fluorescence in situ hybridization: Diagnostic utility for neuroblastoma
-
Shapiro DN, Valentine MB, Rowe ST, Sinclair AE, Sublett JE, Roberts WM, et al. Detection of N-myc gene amplification by fluorescence in situ hybridization. Diagnostic utility for neuroblastoma. Am J Pathol 1993;142:1339-46. (Pubitemid 24058120)
-
(1993)
American Journal of Pathology
, vol.142
, Issue.5
, pp. 1339-1346
-
-
Shapiro, D.N.1
Valentine, M.B.2
Rowe, S.T.3
Sinclair, A.E.4
Sublett, J.E.5
Roberts, W.M.6
Look, A.T.7
-
82
-
-
79960623998
-
The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy
-
Savino M, Annibali D, Carucci N, Favuzzi E, Cole MD, Evan GI, et al. The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy. PLoS ONE 2011;6:e22284.
-
(2011)
PLoS ONE
, vol.6
-
-
Savino, M.1
Annibali, D.2
Carucci, N.3
Favuzzi, E.4
Cole, M.D.5
Evan, G.I.6
-
83
-
-
4444361372
-
The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells
-
DOI 10.1016/j.bcp.2004.05.010, PII S0006295204003120
-
de Ruijter AJ, Kemp S, Kramer G, Meinsma RJ, Kaufmann JO, Caron HN, et al. The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells. Biochem Pharmacol 2004;68:1279-88. (Pubitemid 39179387)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.7
, pp. 1279-1288
-
-
De Ruijter, A.J.M.1
Kemp, S.2
Kramer, G.3
Meinsma, R.J.4
Kaufmann, J.O.5
Caron, H.N.6
Van Kuilenburg, A.B.P.7
-
84
-
-
24944585561
-
Gene expression profiling in response to the histone deacetylase inhibitor BL1521 in neuroblastoma
-
DOI 10.1016/j.yexcr.2005.06.024, PII S0014482705003071
-
de Ruijter AJ, Meinsma RJ, Bosma P, Kemp S, Caron HN, van Kuilenburg AB. Gene expression pro filing in response to the histone deacetylase inhibitor BL1521 in neuroblastoma. Exp Cell Res 2005;309:451-67. (Pubitemid 41317368)
-
(2005)
Experimental Cell Research
, vol.309
, Issue.2
, pp. 451-467
-
-
De Ruijter, A.J.M.1
Meinsma, R.J.2
Bosma, P.3
Kemp, S.4
Caron, H.N.5
Van Kuilenburg, A.B.P.6
-
85
-
-
80053651202
-
Targeting MYC dependence in cancer by inhibiting BET bromodomains
-
Mertz JA, Conery AR, Bryant BM, Sandy P, Balasubramanian S, Mele DA, et al. Targeting MYC dependence in cancer by inhibiting BET bromodomains. Proc Natl Acad Sci U S A 2011;108:16669-74.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16669-16674
-
-
Mertz, J.A.1
Conery, A.R.2
Bryant, B.M.3
Sandy, P.4
Balasubramanian, S.5
Mele, D.A.6
-
86
-
-
84876033650
-
Targeting MYCN in neuroblastoma by BET bromodomain inhibition
-
Puissant A, Frumm SM, Alexe G, Bassil CF, Qi J, Chanthery YH, et al. Targeting MYCN in neuroblastoma by BET bromodomain inhibition. Cancer Discov 2013;3:308-23.
-
(2013)
Cancer Discov
, vol.3
, pp. 308-323
-
-
Puissant, A.1
Frumm, S.M.2
Alexe, G.3
Bassil, C.F.4
Qi, J.5
Chanthery, Y.H.6
-
87
-
-
77953850924
-
Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237
-
Sloane DA, Trikic MZ, Chu ML, Lamers MB, Mason CS, Mueller I, et al. Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237. ACS Chem Biol 2010;5:563-76.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 563-576
-
-
Sloane, D.A.1
Trikic, M.Z.2
Chu, M.L.3
Lamers, M.B.4
Mason, C.S.5
Mueller, I.6
-
88
-
-
84880042989
-
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma
-
Brockmann M, Poon E, Berry T, Carstensen A, Deubzer HE, Rycak L, et al. Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma. Cancer Cell 2013; 24:75-89.
-
(2013)
Cancer Cell
, vol.24
, pp. 75-89
-
-
Brockmann, M.1
Poon, E.2
Berry, T.3
Carstensen, A.4
Deubzer, H.E.5
Rycak, L.6
-
89
-
-
84867534947
-
CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs
-
Walton MI, Eve PD, Hayes A, Valenti MR, De Haven Brandon AK, Box G, et al. CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs. Clin Cancer Res 2012;18:5650-61.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5650-5661
-
-
Walton, M.I.1
Eve, P.D.2
Hayes, A.3
Valenti, M.R.4
De Haven Brandon, A.K.5
Box, G.6
-
90
-
-
70349115668
-
The PI3K/Akt/mTOR pathway as therapeutic target in neuroblastoma
-
Fulda S. The PI3K/Akt/mTOR pathway as therapeutic target in neuroblastoma. Curr Cancer Drug Targets 2009;9:729-37.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 729-737
-
-
Fulda, S.1
-
91
-
-
84855374142
-
Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma
-
Chanthery YH, Gustafson WC, Itsara M, Persson A, Hackett CS, Grimmer M, et al. Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma. Sci Transl Med 2012; 4:115ra3.
-
(2012)
Sci Transl Med
, vol.4
-
-
Chanthery, Y.H.1
Gustafson, W.C.2
Itsara, M.3
Persson, A.4
Hackett, C.S.5
Grimmer, M.6
-
92
-
-
0036245047
-
MYCC and MYCN oncogene amplification in medulloblastoma: A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group
-
Aldosari N, Bigner SH, Burger PC, Becker L, Kepner JL, Friedman HS, et al. MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group. Arch Pathol Lab Med 2002;126:540-4. (Pubitemid 34477948)
-
(2002)
Archives of Pathology and Laboratory Medicine
, vol.126
, Issue.5
, pp. 540-544
-
-
Aldosari, N.1
Bigner, S.H.2
Burger, P.C.3
Becker, L.4
Kepner, J.L.5
Friedman, H.S.6
McLendon, R.E.7
-
93
-
-
70349630234
-
Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts
-
Hodgson JG, Yeh RF, Ray A, Wang NJ, Smirnov I, Yu M, et al. Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. Neuro Oncol 2009;11:477- 87.
-
(2009)
Neuro Oncol
, vol.11
, pp. 477-487
-
-
Hodgson, J.G.1
Yeh, R.F.2
Ray, A.3
Wang, N.J.4
Smirnov, I.5
Yu, M.6
-
94
-
-
84856530750
-
Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy
-
Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, et al. Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy. Clin Cancer Res 2012;18:796- 807.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 796-807
-
-
Tonelli, R.1
McIntyre, A.2
Camerin, C.3
Walters, Z.S.4
Di Leo, K.5
Selfe, J.6
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