-
1
-
-
51649085884
-
Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation
-
Ando K, Ohira M, Ozaki T, Nakagawa A, Akazawa K, Suenaga Y et al. (2008). Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation. Int J Cancer 123: 2087-2094.
-
(2008)
Int J Cancer
, vol.123
, pp. 2087-2094
-
-
Ando, K.1
Ohira, M.2
Ozaki, T.3
Nakagawa, A.4
Akazawa, K.5
Suenaga, Y.6
-
2
-
-
0035573732
-
Production of monoclonal antibodies against mammalian Ring1B proteins
-
Atsuta T, Fujimura S, Moriya H, Vidal M, Akasaka T, Koseki H. (2001). Production of monoclonal antibodies against mammalian Ring1B proteins. Hybridoma 20: 43-46.
-
(2001)
Hybridoma
, vol.20
, pp. 43-46
-
-
Atsuta, T.1
Fujimura, S.2
Moriya, H.3
Vidal, M.4
Akasaka, T.5
Koseki, H.6
-
3
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. (1984). Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224: 1121-1124.
-
(1984)
Science
, vol.224
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
Varmus, H.E.4
Bishop, J.M.5
-
4
-
-
35148840173
-
Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
-
Bruggeman SW, Hulsman D, Tanger E, Buckle T, Blom M, Zevenhoven J et al. (2007). Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 12: 328-341.
-
(2007)
Cancer Cell
, vol.12
, pp. 328-341
-
-
Bruggeman, S.W.1
Hulsman, D.2
Tanger, E.3
Buckle, T.4
Blom, M.5
Zevenhoven, J.6
-
5
-
-
29144487990
-
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
-
Cao R, Tsukada Y, Zhang Y. (2005). Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell 20: 845-854.
-
(2005)
Mol Cell
, vol.20
, pp. 845-854
-
-
Cao, R.1
Tsukada, Y.2
Zhang, Y.3
-
6
-
-
0028944776
-
Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma
-
Caron H. (1995). Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma. Med Pediatr Oncol 24: 215-221.
-
(1995)
Med Pediatr Oncol
, vol.24
, pp. 215-221
-
-
Caron, H.1
-
7
-
-
26844489696
-
A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation
-
Caren H, Ejeskar K, Fransson S, Hesson L, Latif F, Sjoberg RM et al. (2005). A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation. Mol Cancer 4: 10.
-
(2005)
Mol Cancer
, vol.4
, pp. 10
-
-
Caren, H.1
Ejeskar, K.2
Fransson, S.3
Hesson, L.4
Latif, F.5
Sjoberg, R.M.6
-
8
-
-
33845943728
-
Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblas-toma cells in a concentration-dependent manner
-
Cui H, Ma J, Ding J, Li T, Alam G, Ding HF. (2006). Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblas-toma cells in a concentration-dependent manner. J Biol Chem 281: 34696-34704.
-
(2006)
J Biol Chem
, vol.281
, pp. 34696-34704
-
-
Cui, H.1
Ma, J.2
Ding, J.3
Li, T.4
Alam, G.5
Ding, H.F.6
-
9
-
-
34247891673
-
Bmi-1 is essential for the tumorigenicity of neuroblastoma cells
-
Cui H, Hu B, Li T, Ma J, Alam G, Gunning WT et al. (2007). Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol 170: 1370-1378.
-
(2007)
Am J Pathol
, vol.170
, pp. 1370-1378
-
-
Cui, H.1
Hu, B.2
Li, T.3
Ma, J.4
Alam, G.5
Gunning, W.T.6
-
10
-
-
0032525883
-
Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma
-
Easton J, Wei T, Lahti JM, Kidd VJ. (1998). Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma. Cancer Res 58: 2624-2632.
-
(1998)
Cancer Res
, vol.58
, pp. 2624-2632
-
-
Easton, J.1
Wei, T.2
Lahti, J.M.3
Kidd, V.J.4
-
11
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. (2007). Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8: 286-298.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
12
-
-
33745883297
-
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8
-
Fujimura Y, Isono K, Vidal M, Endoh M, Kajita H, Mizutani-Koseki Y et al. (2006). Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8. Development 133: 2371-2381.
-
(2006)
Development
, vol.133
, pp. 2371-2381
-
-
Fujimura, Y.1
Isono, K.2
Vidal, M.3
Endoh, M.4
Kajita, H.5
Mizutani-Koseki, Y.6
-
13
-
-
33644871338
-
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a
-
Guney I, Wu S, Sedivy JM. (2006). Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci USA 103: 3645-3650.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3645-3650
-
-
Guney, I.1
Wu, S.2
Sedivy, J.M.3
-
14
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
10344258563
-
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
-
Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, Tsukui H et al. (2004). Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21: 843-851.
-
(2004)
Immunity
, vol.21
, pp. 843-851
-
-
Iwama, A.1
Oguro, H.2
Negishi, M.3
Kato, Y.4
Morita, Y.5
Tsukui, H.6
-
16
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. (1999). The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397: 164-168.
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
Depinho, R.A.4
Van Lohuizen, M.5
-
17
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. (2002). The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
18
-
-
33344469959
-
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga LM, Bystrykh LV, de Boer A, Houwer S, Douma J, Weersing E et al. (2005). The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107: 2170-2179.
-
(2005)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
Bystrykh, L.V.2
De Boer, A.3
Houwer, S.4
Douma, J.5
Weersing, E.6
-
19
-
-
33749047273
-
Cellular memory and hemato-poietic stem cell aging
-
Kamminga LM, de Haan G. (2006). Cellular memory and hemato-poietic stem cell aging. Stem Cells 24: 1143-1149.
-
(2006)
Stem Cells
, vol.24
, pp. 1143-1149
-
-
Kamminga, L.M.1
De Haan, G.2
-
20
-
-
1242339706
-
E2F and Sp1/Sp3 synergize but are not sufficient to activate the MYCN gene in neuroblastomas
-
Kramps C, Strieder V, Sapetschnig A, Suske G, Lutz W. (2004). E2F and Sp1/Sp3 synergize but are not sufficient to activate the MYCN gene in neuroblastomas. J Biol Chem 279: 5110-5117.
-
(2004)
J Biol Chem
, vol.279
, pp. 5110-5117
-
-
Kramps, C.1
Strieder, V.2
Sapetschnig, A.3
Suske, G.4
Lutz, W.5
-
21
-
-
38749115021
-
Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuro-blastoma cells
-
Kurata K, Yanagisawa R, Ohira M, Kitagawa M, Nakagawara A, Kamijo T. (2008). Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuro-blastoma cells. Oncogene 27: 741-754.
-
(2008)
Oncogene
, vol.27
, pp. 741-754
-
-
Kurata, K.1
Yanagisawa, R.2
Ohira, M.3
Kitagawa, M.4
Nakagawara, A.5
Kamijo, T.6
-
22
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. (2003). Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
23
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P et al. (2004). Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428: 337-341.
-
(2004)
Nature
, vol.428
, pp. 337-341
-
-
Leung, C.1
Lingbeek, M.2
Shakhova, O.3
Liu, J.4
Tanger, E.5
Saremaslani, P.6
-
24
-
-
0029743372
-
Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
-
Lutz W, Stohr M, Schurmann J, Wenzel A, Lohr A, Schwab M. (1996). Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 13: 803-812.
-
(1996)
Oncogene
, vol.13
, pp. 803-812
-
-
Lutz, W.1
Stohr, M.2
Schurmann, J.3
Wenzel, A.4
Lohr, A.5
Schwab, M.6
-
25
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
26
-
-
33749171885
-
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishna-murthy J et al. (2006). Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443: 448-452.
-
(2006)
Nature
, vol.443
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
He, S.4
Pardal, R.5
Krishna-Murthy, J.6
-
27
-
-
54049148638
-
KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death
-
Munirajan AK, Ando K, Mukai A, Takahashi M, Suenaga Y, Ohira M et al. (2008). KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death. J Biol Chem 283: 24426-24434.
-
(2008)
J Biol Chem
, vol.283
, pp. 24426-24434
-
-
Munirajan, A.K.1
Ando, K.2
Mukai, A.3
Takahashi, M.4
Suenaga, Y.5
Ohira, M.6
-
28
-
-
27144524031
-
Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis
-
Murakami Y. (2005). Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis. Cancer Sci 96: 543-552.
-
(2005)
Cancer Sci
, vol.96
, pp. 543-552
-
-
Murakami, Y.1
-
29
-
-
33645826712
-
BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas
-
Nowak K, Kerl K, Fehr D, Kramps C, Gessner C, Killmer K et al. (2006). BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas. Nucleic Acids Res 34: 1745-1754.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1745-1754
-
-
Nowak, K.1
Kerl, K.2
Fehr, D.3
Kramps, C.4
Gessner, C.5
Killmer, K.6
-
30
-
-
20244385561
-
Expression profiling using a tumor-specific cDNA micro-array predicts the prognosis of intermediate risk neuroblastomas
-
Ohira M, Oba S, Nakamura Y, Isogai E, Kaneko S, Nakagawa A et al. (2005). Expression profiling using a tumor-specific cDNA micro-array predicts the prognosis of intermediate risk neuroblastomas. Cancer Cell 7: 337-350.
-
(2005)
Cancer Cell
, vol.7
, pp. 337-350
-
-
Ohira, M.1
Oba, S.2
Nakamura, Y.3
Isogai, E.4
Kaneko, S.5
Nakagawa, A.6
-
31
-
-
0031080378
-
Analysis of chromatin structure by in vivo formaldehyde cross-linking
-
Orlando V, Strutt H, Paro R. (1997). Analysis of chromatin structure by in vivo formaldehyde cross-linking. Methods 11: 205-214.
-
(1997)
Methods
, vol.11
, pp. 205-214
-
-
Orlando, V.1
Strutt, H.2
Paro, R.3
-
32
-
-
41749108163
-
Stem cell regulation by polycomb repressors: Postponing commitment
-
Pietersen AM, van Lohuizen M. (2008). Stem cell regulation by polycomb repressors: postponing commitment. Curr Opin Cell Biol 20: 201-207.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 201-207
-
-
Pietersen, A.M.1
Van Lohuizen, M.2
-
33
-
-
35348850693
-
Concise review: Roles of polycomb group proteins in development and disease: A stem cell perspective
-
Rajasekhar VK, Begemann M. (2007). Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective. Stem Cells 25: 2498-2510.
-
(2007)
Stem Cells
, vol.25
, pp. 2498-2510
-
-
Rajasekhar, V.K.1
Begemann, M.2
-
34
-
-
44649200464
-
Polycomb complexes and epigenetic states
-
Schwartz YB, Pirrotta V. (2008). Polycomb complexes and epigenetic states. Curr Opin Cell Biol 20: 266-273.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 266-273
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
35
-
-
0842346437
-
Principles of tumor suppression
-
Sherr CJ. (2004). Principles of tumor suppression. Cell 116: 235-246.
-
(2004)
Cell
, vol.116
, pp. 235-246
-
-
Sherr, C.J.1
-
36
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann A, van Lohuizen M. (2006). Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6: 846-856.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 846-856
-
-
Sparmann, A.1
Van Lohuizen, M.2
-
37
-
-
0037474220
-
E2F proteins regulate MYCN expression in neuroblastomas
-
Strieder V, Lutz W. (2003). E2F proteins regulate MYCN expression in neuroblastomas. J Biol Chem 278: 2983-2989.
-
(2003)
J Biol Chem
, vol.278
, pp. 2983-2989
-
-
Strieder, V.1
Lutz, W.2
-
38
-
-
36349009317
-
Epigenetic silencing of prostaglandin e receptor 2 (PTGER2) is associated with progression of neuroblastomas
-
Sugino Y, Misawa A, Inoue J, Kitagawa M, Hosoi H, Sugimoto T et al. (2007). Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas. Oncogene 26: 7401-7413.
-
(2007)
Oncogene
, vol.26
, pp. 7401-7413
-
-
Sugino, Y.1
Misawa, A.2
Inoue, J.3
Kitagawa, M.4
Hosoi, H.5
Sugimoto, T.6
-
39
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
-
Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA et al. (2000). Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 6: 529-535.
-
(2000)
Nat Med
, vol.6
, pp. 529-535
-
-
Teitz, T.1
Wei, T.2
Valentine, M.B.3
Vanin, E.F.4
Grenet, J.5
Valentine, V.A.6
-
41
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C et al. (2006). The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439: 871-874.
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
-
42
-
-
0037190798
-
Genetic parameters of neuroblas-tomas
-
Westemann F, Schwab M. (2002). Genetic parameters of neuroblas-tomas. Cancer Lett 184: 127-147.
-
(2002)
Cancer Lett
, vol.184
, pp. 127-147
-
-
Westemann, F.1
Schwab, M.2
-
43
-
-
0037301110
-
Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma
-
Yan P, Muhlethaler A, Bourloud KB, Beck MN, Gross N. (2003). Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma. Gene Chromosomes Cancer 36: 129-138.
-
(2003)
Gene Chromosomes Cancer
, vol.36
, pp. 129-138
-
-
Yan, P.1
Muhlethaler, A.2
Bourloud, K.B.3
Beck, M.N.4
Gross, N.5
-
44
-
-
11144229611
-
Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma
-
Yang Q, Zage P, Kagan D, Tian Y, Seshadri R, Salwen HR et al. (2004). Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma. Clin Cancer Res 10: 8493-8500.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8493-8500
-
-
Yang, Q.1
Zage, P.2
Kagan, D.3
Tian, Y.4
Seshadri, R.5
Salwen, H.R.6
-
45
-
-
0141885092
-
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma
-
Yang QW, Liu S, Tian Y, Salwen HR, Chlenski A, Weinstein J et al. (2003). Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma. Cancer Res 63: 6299-6310.
-
(2003)
Cancer Res
, vol.63
, pp. 6299-6310
-
-
Yang, Q.W.1
Liu, S.2
Tian, Y.3
Salwen, H.R.4
Chlenski, A.5
Weinstein, J.6
-
46
-
-
34547495258
-
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells
-
Yang J, Chai L, Liu F, Fink LM, Lin P, Silberstein LE et al. (2007). Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells. Proc Natl Acad Sci USA 104: 10494-10499.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10494-10499
-
-
Yang, J.1
Chai, L.2
Liu, F.3
Fink, L.M.4
Lin, P.5
Silberstein, L.E.6
|