Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Murphy, Derek M ^a,b   Buckley, Patrick G ^a,b   Bryan, Kenneth ^a,b   Das, Sudipto ^a,b   Alcock, Leah ^a,b   Foley, Niamh H ^a,b   Prenter, Suzanne ^a,b   Bray, Isabella ^a,b   Watters, Karen M ^a,b   Higgins, Desmond ^c   Stallings, Raymond L ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MYCN; UNCLASSIFIED DRUG; MICRORNA; MIRN135 MICRORNA, HUMAN; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; SPACER DNA;

ANIMAL CELL; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA METHYLATION; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HEMIZYGOSITY; HUMAN; HUMAN CELL; NEUROBLASTOMA; NONHUMAN; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE; E BOX ELEMENT; GENE LOCUS; GENETICS; METABOLISM; TUMOR CELL LINE;

BINDING SITES; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; DNA, INTERGENIC; E-BOX ELEMENTS; GENETIC LOCI; HUMANS; MICRORNAS; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 77949524622     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008154     Document Type: Article

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