Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway

International Journal of Oncology

Volumn 45, Issue 2, 2014, Pages 611-618

  Li, Xin Xiang ^a   Huang, Li Yong ^a   Peng, Jun Jie ^a   Liang, Lei ^a   Shi, De Bing ^a   Zheng, Hong Tu ^a   Cai, San Jun ^a  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

Colon cancer; Growth; Invasion; Klotho

Indexed keywords

CYCLINE; GELATINASE A; KLOTHO PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN; BETA GLUCURONIDASE; SOMATOMEDIN C RECEPTOR; TUMOR MARKER;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER STAGING; CANCER TISSUE; CELL ACTIVITY; CELL INVASION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; CORRELATIONAL STUDY; DOWN REGULATION; DUKE STAGING; FEMALE; GENE OVEREXPRESSION; HT 29 CELL LINE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR INVASION; TUMOR MODEL; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; TUMOR XENOGRAFT; AGED; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; COLON TUMOR; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; WESTERN BLOTTING; XENOGRAFT;

AGED; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; COLONIC NEOPLASMS; FEMALE; GLUCURONIDASE; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84902589563     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2430     Document Type: Article

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