βKlotho Suppresses Tumor Growth in Hepatocellular Carcinoma by Regulating Akt/GSK-3β/Cyclin D1 Signaling Pathway

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Ye, Xiaoming ^a,b   Guo, Yu ^a,b   Zhang, Qi ^a,b   Chen, Wenjie ^a,b   Hua, Xuefeng ^b   Liu, Wei ^a   Yang, Yang ^a,b   Chen, Guihua ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangdong Provincial Key Laboratory of Liver Disease Research   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA KLOTHO PROTEIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3ALPHA; KLOTHO PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GROWTH INHIBITION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; S PHASE CELL CYCLE CHECKPOINT; UPREGULATION;

ADULT; AGED; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCURONIDASE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LIVER NEOPLASMS; MALE; MICE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84873861777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055615     Document Type: Article

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