-
1
-
-
41149180788
-
Cancer vaccines for established cancer: How to make them better?
-
Andrews DM, Maraskovsky E, Smyth MJ (2008) Cancer vaccines for established cancer: how to make them better? Immunol Rev 222:242-255.
-
(2008)
Immunol Rev
, vol.222
, pp. 242-255
-
-
Andrews, D.M.1
Maraskovsky, E.2
Smyth, M.J.3
-
2
-
-
40349113184
-
Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming
-
Atanackovic D, Altorki NK, Cao Y, Ritter E, Ferrara CA, Ritter G, Hoffman EW, Bokemeyer C, Old LJ, Gnjatic S (2008) Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming. Proc Natl Acad Sci USA 105:1650-1655.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1650-1655
-
-
Atanackovic, D.1
Altorki, N.K.2
Cao, Y.3
Ritter, E.4
Ferrara, C.A.5
Ritter, G.6
Hoffman, E.W.7
Bokemeyer, C.8
Old, L.J.9
Gnjatic, S.10
-
3
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M, Paradise C, Kunkel L, Rosenberg SA (1999) High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 17:2105-2116.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
Abrams, J.7
Sznol, M.8
Parkinson, D.9
Hawkins, M.10
Paradise, C.11
Kunkel, L.12
Rosenberg, S.A.13
-
4
-
-
34247261531
-
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
-
Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, Banham AH (2006) Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 24:5373-5380.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
Leek, R.D.4
Garcia, J.F.5
Harris, A.L.6
Banham, A.H.7
-
5
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G, Landes S, Kneller A, Leiba M, Koren-Michowitz M, Shimoni A, Nagler A (2008) Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res 14:3044-3051.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
Landes, S.4
Kneller, A.5
Leiba, M.6
Koren-Michowitz, M.7
Shimoni, A.8
Nagler, A.9
-
6
-
-
34748909630
-
Enhancing cancer vaccines with immunomodulators
-
Berinstein NL (2007) Enhancing cancer vaccines with immunomodulators. Vaccine 25(Suppl 2): B72-B88.
-
(2007)
Vaccine
, vol.25
-
-
Berinstein, N.L.1
-
7
-
-
0041736386
-
Immune mechanisms in bacillus Calmette-Guerin immunotherapy for superficial bladder cancer
-
Bohle A, Brandau S (2003) Immune mechanisms in bacillus Calmette-Guerin immunotherapy for superficial bladder cancer. J Urol 170:964-969.
-
(2003)
J Urol
, vol.170
, pp. 964-969
-
-
Bohle, A.1
Brandau, S.2
-
8
-
-
0037122011
-
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
-
Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 196:1627-1638.
-
(2002)
J Exp Med
, vol.196
, pp. 1627-1638
-
-
Bonifaz, L.1
Bonnyay, D.2
Mahnke, K.3
Rivera, M.4
Nussenzweig, M.C.5
Steinman, R.M.6
-
9
-
-
34748815649
-
GSK’s antigen-specific cancer immunotherapy programme: Pilot results leading to Phase III clinical development
-
Brichard VG, Lejeune D (2007) GSK’s antigen-specific cancer immunotherapy programme: pilot results leading to Phase III clinical development. Vaccine 25(Suppl 2):B61-B71.
-
(2007)
Vaccine
, vol.25
-
-
Brichard, V.G.1
Lejeune, D.2
-
10
-
-
0034900174
-
Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
-
Bross PF, Beitz J, Chen G, Chen XH, Duffy E, Kieffer L, Roy S, Sridhara R, Rahman A, Williams G, Pazdur R (2001) Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 7:1490-1496.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1490-1496
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Chen, X.H.4
Duffy, E.5
Kieffer, L.6
Roy, S.7
Sridhara, R.8
Rahman, A.9
Williams, G.10
Pazdur, R.11
-
11
-
-
35648938219
-
Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
-
Bukowski RM, Kabbinavar FF, Figlin RA, Flaherty K, Srinivas S, Vaishampayan U, Drabkin HA, Dutcher J, Ryba S, Xia Q, Scappaticci FA, McDermott D (2007) Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. J Clin Oncol 25:4536-4541.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4536-4541
-
-
Bukowski, R.M.1
Kabbinavar, F.F.2
Figlin, R.A.3
Flaherty, K.4
Srinivas, S.5
Vaishampayan, U.6
Drabkin, H.A.7
Dutcher, J.8
Ryba, S.9
Xia, Q.10
Scappaticci, F.A.11
McDermott, D.12
-
12
-
-
0033016566
-
Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance
-
Byrd JC, Waselenko JK, Maneatis TJ, Murphy T, Ward FT, Monahan BP, Sipe MA, Donegan S, White CA (1999) Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: association with increased infusion-related side effects and rapid blood tumor clearance. J Clin Oncol 17:791-795.
-
(1999)
J Clin Oncol
, vol.17
, pp. 791-795
-
-
Byrd, J.C.1
Waselenko, J.K.2
Maneatis, T.J.3
Murphy, T.4
Ward, F.T.5
Monahan, B.P.6
Sipe, M.A.7
Donegan, S.8
White, C.A.9
-
13
-
-
0036464719
-
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
-
Cartron G, Dacheux L, Salles G, Solal-Celigny P, Bardos P, Colombat P, Watier H (2002) Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 99:754-758.
-
(2002)
Blood
, vol.99
, pp. 754-758
-
-
Cartron, G.1
Dacheux, L.2
Salles, G.3
Solal-Celigny, P.4
Bardos, P.5
Colombat, P.6
Watier, H.7
-
14
-
-
0034694947
-
Hepatitis B vaccination and hepatocellular carcinoma rates in boys and girls
-
Chang MH, Shau WY, Chen CJ, Wu TC, Kong MS, Liang DC, Hsu HM, Chen HL, Hsu HY, Chen DS (2000) Hepatitis B vaccination and hepatocellular carcinoma rates in boys and girls. JAMA284:3040-3042.
-
(2000)
JAMA
, vol.284
, pp. 3040-3042
-
-
Chang, M.H.1
Shau, W.Y.2
Chen, C.J.3
Wu, T.C.4
Kong, M.S.5
Liang, D.C.6
Hsu, H.M.7
Chen, H.L.8
Hsu, H.Y.9
Chen, D.S.10
-
15
-
-
0037365973
-
Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer
-
Chang AE, Li Q, Jiang G, Sayre DM, Braun TM, Redman BG (2003) Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer. J Clin Oncol 21:884-890.
-
(2003)
J Clin Oncol
, vol.21
, pp. 884-890
-
-
Chang, A.E.1
Li, Q.2
Jiang, G.3
Sayre, D.M.4
Braun, T.M.5
Redman, B.G.6
-
16
-
-
20844451391
-
Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients
-
Chang DH, Osman K, Connolly J, Kukreja A, Krasovsky J, Pack M, Hutchinson A, Geller M, Liu N, Annable R, Shay J, Kirchhoff K, Nishi N, Ando Y, Hayashi K, Hassoun H, Steinman RM, Dhodapkar MV (2005) Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients. J Exp Med 201:1503-1517.
-
(2005)
J Exp Med
, vol.201
, pp. 1503-1517
-
-
Chang, D.H.1
Osman, K.2
Connolly, J.3
Kukreja, A.4
Krasovsky, J.5
Pack, M.6
Hutchinson, A.7
Geller, M.8
Liu, N.9
Annable, R.10
Shay, J.11
Kirchhoff, K.12
Nishi, N.13
Ando, Y.14
Hayashi, K.15
Hassoun, H.16
Steinman, R.M.17
Dhodapkar, M.V.18
-
17
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fehrenbacher L, Wolter JM, Paton V, Shak S, Lieberman G, Slamon DJ (1999) Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol17:2639-2648.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
Robert, N.J.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.M.7
Paton, V.8
Shak, S.9
Lieberman, G.10
Slamon, D.J.11
-
18
-
-
33646419260
-
Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity
-
Cohen AD, Diab A, Perales MA, Wolchok JD, Rizzuto G, Merghoub T, Huggins D, Liu C, Turk MJ, Restifo NP, Sakaguchi S, Houghton AN (2006) Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity. Cancer Res 66:4904-4912.
-
(2006)
Cancer Res
, vol.66
, pp. 4904-4912
-
-
Cohen, A.D.1
Diab, A.2
Perales, M.A.3
Wolchok, J.D.4
Rizzuto, G.5
Merghoub, T.6
Huggins, D.7
Liu, C.8
Turk, M.J.9
Restifo, N.P.10
Sakaguchi, S.11
Houghton, A.N.12
-
19
-
-
34447130180
-
FDA drug approval summary: Bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
-
Cohen MH, Gootenberg J, Keegan P, Pazdur R (2007a) FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer. Oncologist 12:713-718.
-
(2007)
Oncologist
, vol.12
, pp. 713-718
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
Pazdur, R.4
-
20
-
-
34147190880
-
FDA drug approval summary: Bevacizumab plus FOLFOX4 as second-line treatment of colorectal cancer
-
Cohen MH, Gootenberg J, Keegan P, Pazdur R (2007b) FDA drug approval summary: bevacizumab plus FOLFOX4 as second-line treatment of colorectal cancer. Oncologist 12:356-361.
-
(2007)
Oncologist
, vol.12
, pp. 356-361
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
Pazdur, R.4
-
21
-
-
0037165261
-
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
-
Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, Morel P, Van Den Neste E, Salles G, Gaulard P, Reyes F, Lederlin P, Gisselbrecht C (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346:235-242.
-
(2002)
N Engl J Med
, vol.346
, pp. 235-242
-
-
Coiffier, B.1
Lepage, E.2
Briere, J.3
Herbrecht, R.4
Tilly, H.5
Bouabdallah, R.6
Morel, P.7
Van Den Neste, E.8
Salles, G.9
Gaulard, P.10
Reyes, F.11
Lederlin, P.12
Gisselbrecht, C.13
-
22
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA (2007) The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450:566-569.
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
Boyd, K.4
Wang, Y.5
Vignali, K.M.6
Cross, R.7
Sehy, D.8
Blumberg, R.S.9
Vignali, D.A.10
-
23
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, Conejo-Garcia JR, Zhang L, Burow M, Zhu Y, Wei S, Kryczek I, Daniel B, Gordon A, Myers L, Lackner A, Disis ML, Knutson KL, Chen L, Zou W (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10:942-949.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
Zhu, Y.11
Wei, S.12
Kryczek, I.13
Daniel, B.14
Gordon, A.15
Myers, L.16
Lackner, A.17
Disis, M.L.18
Knutson, K.L.19
Chen, L.20
Zou, W.21
more..
-
24
-
-
30144444279
-
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
-
Dannull J, Su Z, Rizzieri D, Yang BK, Coleman D, Yancey D, Zhang A, Dahm P, Chao N, Gilboa E, Vieweg J (2005) Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 115:3623-3633.
-
(2005)
J Clin Invest
, vol.115
, pp. 3623-3633
-
-
Dannull, J.1
Su, Z.2
Rizzieri, D.3
Yang, B.K.4
Coleman, D.5
Yancey, D.6
Zhang, A.7
Dahm, P.8
Chao, N.9
Gilboa, E.10
Vieweg, J.11
-
25
-
-
27644553811
-
Experience with hepatitis A and B vaccines
-
Davis JP (2005) Experience with hepatitis A and B vaccines. Am J Med 118(Suppl 10A):7S-15S.
-
(2005)
Am J Med
, vol.118
, Issue.10A
-
-
Davis, J.P.1
-
27
-
-
33947545402
-
The use of aspirin for primary prevention of colorectal cancer: A systematic review prepared for the U.S. Preventive Services Task Force
-
Dube C, Rostom A, Lewin G, Tsertsvadze A, Barrowman N, Code C, Sampson M, Moher D(2007) The use of aspirin for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force. Ann Intern Med 146:365-375.
-
(2007)
Ann Intern Med
, vol.146
, pp. 365-375
-
-
Dube, C.1
Rostom, A.2
Lewin, G.3
Tsertsvadze, A.4
Barrowman, N.5
Code, C.6
Sampson, M.7
Moher, D.8
-
28
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry R, Restifo NP, Hubicki AM, Robinson MR, Raffeld M, Duray P, Seipp CA, RogersFreezer L, Morton KE, Mavroukakis SA, White DE, Rosenberg SA (2002) Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science298:850-854.
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Robbins, P.F.3
Yang, J.C.4
Hwu, P.5
Schwartzentruber, D.J.6
Topalian, S.L.7
Sherry, R.8
Restifo, N.P.9
Hubicki, A.M.10
Robinson, M.R.11
Raffeld, M.12
Duray, P.13
Seipp, C.A.14
Rogersfreezer, L.15
Morton, K.E.16
Mavroukakis, S.A.17
White, D.E.18
Rosenberg, S.A.19
-
29
-
-
0037829421
-
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
-
Dudley ME, Wunderlich JR, Shelton TE, Even J, Rosenberg SA (2003) Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother 26:332-342.
-
(2003)
J Immunother
, vol.26
, pp. 332-342
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Shelton, T.E.3
Even, J.4
Rosenberg, S.A.5
-
30
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Dudley ME, Wunderlich JR, Yang JC, Sherry RM, Topalian SL, Restifo NP, Royal RE, Kammula U, White DE, Mavroukakis SA, Rogers LJ, Gracia GJ, Jones SA, Mangiameli DP, Pelletier MM, Gea-Banacloche J, Robinson MR, Berman DM, Filie AC, Abati A, Rosenberg SA (2005)Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol23:2346-2357.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
Sherry, R.M.4
Topalian, S.L.5
Restifo, N.P.6
Royal, R.E.7
Kammula, U.8
White, D.E.9
Mavroukakis, S.A.10
Rogers, L.J.11
Gracia, G.J.12
Jones, S.A.13
Mangiameli, D.P.14
Pelletier, M.M.15
Gea-Banacloche, J.16
Robinson, M.R.17
Berman, D.M.18
Filie, A.C.19
Abati, A.20
Rosenberg, S.A.21
more..
-
32
-
-
22144465860
-
A critical function for type I interferons in cancer immunoediting
-
Dunn GP, Bruce AT, Sheehan KC, Shankaran V, Uppaluri R, Bui JD, Diamond MS, Koebel CM, Arthur C, White JM, Schreiber RD (2005) A critical function for type I interferons in cancer immunoediting. Nat Immunol 6:722-729.
-
(2005)
Nat Immunol
, vol.6
, pp. 722-729
-
-
Dunn, G.P.1
Bruce, A.T.2
Sheehan, K.C.3
Shankaran, V.4
Uppaluri, R.5
Bui, J.D.6
Diamond, M.S.7
Koebel, C.M.8
Arthur, C.9
White, J.M.10
Schreiber, R.D.11
-
33
-
-
33744527899
-
Helicobacterpylori infection causes gastric cancer? A review of the epidemiological, meta-analytic, and experimental evidence
-
Eslick GD (2006) Helicobacterpylori infection causes gastric cancer? A review of the epidemiological, meta-analytic, and experimental evidence. World J Gastroenterol 12:2991-2999.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 2991-2999
-
-
Eslick, G.D.1
-
34
-
-
32944476224
-
Tositumomab and iodine-131 tositumomab produces durable complete remissions in a subset of heavily pretreated patients with low-grade and transformed non-Hodgkin’s lymphomas
-
Fisher RI, Kaminski MS, Wahl RL, Knox SJ, Zelenetz AD, Vose JM, Leonard JP, Kroll S, Goldsmith SJ, Coleman M (2005) Tositumomab and iodine-131 tositumomab produces durable complete remissions in a subset of heavily pretreated patients with low-grade and transformed non-Hodgkin’s lymphomas. J Clin Oncol 23:7565-7573.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7565-7573
-
-
Fisher, R.I.1
Kaminski, M.S.2
Wahl, R.L.3
Knox, S.J.4
Zelenetz, A.D.5
Vose, J.M.6
Leonard, J.P.7
Kroll, S.8
Goldsmith, S.J.9
Coleman, M.10
-
35
-
-
0032896709
-
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
-
French RR, Chan HT, Tutt AL, Glennie MJ (1999) CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med 5:548-553.
-
(1999)
Nat Med
, vol.5
, pp. 548-553
-
-
French, R.R.1
Chan, H.T.2
Tutt, A.L.3
Glennie, M.J.4
-
36
-
-
34248326338
-
Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions
-
Future, II Study Group (2007) Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions. N Engl J Med 356:1915-1927.
-
(2007)
N Engl J Med
, vol.356
, pp. 1915-1927
-
-
-
37
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
Fyfe G, Fisher RI, Rosenberg SA, Sznol M, Parkinson DR, Louie AC (1995) Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 13:688-696.
-
(1995)
J Clin Oncol
, vol.13
, pp. 688-696
-
-
Fyfe, G.1
Fisher, R.I.2
Rosenberg, S.A.3
Sznol, M.4
Parkinson, D.R.5
Louie, A.C.6
-
38
-
-
0028204442
-
Identical-twin bone marrow transplants for leukemia
-
Gale RP, Horowitz MM, Ash RC, Champlin RE, Goldman JM, Rimm AA, Ringden O, Stone JA, Bortin MM (1994) Identical-twin bone marrow transplants for leukemia. Ann Intern Med120:646-652.
-
(1994)
Ann Intern Med
, vol.120
, pp. 646-652
-
-
Gale, R.P.1
Horowitz, M.M.2
Ash, R.C.3
Champlin, R.E.4
Goldman, J.M.5
Rimm, A.A.6
Ringden, O.7
Stone, J.A.8
Bortin, M.M.9
-
39
-
-
34248365967
-
Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases
-
Garland SM, Hernandez-Avila M, Wheeler CM, Perez G, Harper DM, Leodolter S, Tang GW, Ferris DG, Steben M, Bryan J, Taddeo FJ, Railkar R, Esser MT, Sings HL, Nelson M, Boslego J, Sattler C, Barr E, Koutsky LA (2007) Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases. N Engl J Med 356:1928-1943.
-
(2007)
N Engl J Med
, vol.356
, pp. 1928-1943
-
-
Garland, S.M.1
Hernandez-Avila, M.2
Wheeler, C.M.3
Perez, G.4
Harper, D.M.5
Leodolter, S.6
Tang, G.W.7
Ferris, D.G.8
Steben, M.9
Bryan, J.10
Taddeo, F.J.11
Railkar, R.12
Esser, M.T.13
Sings, H.L.14
Nelson, M.15
Boslego, J.16
Sattler, C.17
Barr, E.18
Koutsky, L.A.19
-
40
-
-
2342473348
-
Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: Results from two phase III, randomized, vehicle-controlled studies
-
Geisse J, Caro I, Lindholm J, Golitz L, Stampone P, Owens M (2004) Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase III, randomized, vehicle-controlled studies. J Am Acad Dermatol 50:722-733.
-
(2004)
J am Acad Dermatol
, vol.50
, pp. 722-733
-
-
Geisse, J.1
Caro, I.2
Lindholm, J.3
Golitz, L.4
Stampone, P.5
Owens, M.6
-
41
-
-
0036896332
-
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors
-
Giaccone G, Punt CJ, Ando Y, Ruijter R, Nishi N, Peters M, von Blomberg BM, Scheper RJ, Van Der Vliet HJ, van den Eertwegh AJ, Roelvink M, Beijnen J, Zwierzina H, Pinedo HM (2002) A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors. Clin Cancer Res 8:3702-3709.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3702-3709
-
-
Giaccone, G.1
Punt, C.J.2
Ando, Y.3
Ruijter, R.4
Nishi, N.5
Peters, M.6
Von Blomberg, B.M.7
Scheper, R.J.8
Van Der Vliet, H.J.9
Van Den Eertwegh, A.J.10
Roelvink, M.11
Beijnen, J.12
Zwierzina, H.13
Pinedo, H.M.14
-
42
-
-
34548289390
-
FDA drug approval summary: Panitumumab (Vectibix)
-
Giusti RM, Shastri KA, Cohen MH, Keegan P, Pazdur R (2007) FDA drug approval summary: panitumumab (Vectibix). Oncologist 12:577-583.
-
(2007)
Oncologist
, vol.12
, pp. 577-583
-
-
Giusti, R.M.1
Shastri, K.A.2
Cohen, M.H.3
Keegan, P.4
Pazdur, R.5
-
43
-
-
33746211234
-
NY-ESO-1: Review of an immunogenic tumor antigen
-
Gnjatic S, Nishikawa H, Jungbluth AA, Gure AO, Ritter G, Jager E, Knuth A, Chen YT, Old LJ(2006) NY-ESO-1: review of an immunogenic tumor antigen. Adv Cancer Res 95:1-30.
-
(2006)
Adv Cancer Res
, vol.95
, pp. 1-30
-
-
Gnjatic, S.1
Nishikawa, H.2
Jungbluth, A.A.3
Gure, A.O.4
Ritter, G.5
Jager, E.6
Knuth, A.7
Chen, Y.T.8
Old, L.J.9
-
44
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
Gogas H, Ioannovich J, Dafni U, Stavropoulou-Giokas C, Frangia K, Tsoutsos D, Panagiotou P, Polyzos A, Papadopoulos O, Stratigos A, Markopoulos C, Bafaloukos D, Pectasides D, Fountzilas G, Kirkwood JM (2006) Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 354:709-718.
-
(2006)
N Engl J Med
, vol.354
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
Stavropoulou-Giokas, C.4
Frangia, K.5
Tsoutsos, D.6
Panagiotou, P.7
Polyzos, A.8
Papadopoulos, O.9
Stratigos, A.10
Markopoulos, C.11
Bafaloukos, D.12
Pectasides, D.13
Fountzilas, G.14
Kirkwood, J.M.15
-
46
-
-
33645779116
-
Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-alpha and melphalan for limb-threatening soft tissue sarcoma
-
Grunhagen DJ, de Wilt JH, Graveland WJ, Verhoef C, van Geel AN, Eggermont AM (2006) Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-alpha and melphalan for limb-threatening soft tissue sarcoma. Cancer 106:1776-1784.
-
(2006)
Cancer
, vol.106
, pp. 1776-1784
-
-
Grunhagen, D.J.1
De Wilt, J.H.2
Graveland, W.J.3
Verhoef, C.4
Van Geel, A.N.5
Eggermont, A.M.6
-
47
-
-
33745555459
-
Imiquimod for actinic keratosis: Systematic review and meta-analysis
-
Hadley G, Derry S, Moore RA (2006) Imiquimod for actinic keratosis: systematic review and meta-analysis. J Invest Dermatol 126:1251-1255.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1251-1255
-
-
Hadley, G.1
Derry, S.2
Moore, R.A.3
-
48
-
-
0029053868
-
Intravesical bacillus Calmette-Guerin therapy prevents tumor progression and death from superficial bladder cancer: Ten-year follow-up of a prospective randomized trial
-
Herr HW, Schwalb DM, Zhang ZF, Sogani PC, Fair WR, Whitmore WF Jr., Oettgen HF (1995)Intravesical bacillus Calmette-Guerin therapy prevents tumor progression and death from superficial bladder cancer: ten-year follow-up of a prospective randomized trial. J Clin Oncol13:1404-1408.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1404-1408
-
-
Herr, H.W.1
Schwalb, D.M.2
Zhang, Z.F.3
Sogani, P.C.4
Fair, W.R.5
Whitmore, W.F.6
Oettgen, H.F.7
-
49
-
-
0142250380
-
A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients
-
Higuchi T, Iwama T, Yoshinaga K, Toyooka M, Taketo MM, Sugihara K (2003) A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin Cancer Res9:4756-4760.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4756-4760
-
-
Higuchi, T.1
Iwama, T.2
Yoshinaga, K.3
Toyooka, M.4
Taketo, M.M.5
Sugihara, K.6
-
50
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano F, Kaneko K, Tamura H, Dong H, Wang S, Ichikawa M, Rietz C, Flies DB, Lau JS, Zhu G, Tamada K, Chen L (2005) Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res 65:1089-1096.
-
(2005)
Cancer Res
, vol.65
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
Rietz, C.7
Flies, D.B.8
Lau, J.S.9
Zhu, G.10
Tamada, K.11
Chen, L.12
-
51
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi FS, Mihm MC, Soiffer RJ, Haluska FG, Butler M, Seiden MV, Davis T, Henry-Spires R, MacRae S, Willman A, Padera R, Jaklitsch MT, Shankar S, Chen TC, Korman A, Allison JP, Dranoff G (2003) Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci USA 100:4712-4717.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
Haluska, F.G.4
Butler, M.5
Seiden, M.V.6
Davis, T.7
Henry-Spires, R.8
Macrae, S.9
Willman, A.10
Padera, R.11
Jaklitsch, M.T.12
Shankar, S.13
Chen, T.C.14
Korman, A.15
Allison, J.P.16
Dranoff, G.17
-
52
-
-
42949105127
-
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
-
Hodi FS, Butler M, Oble DA, Seiden MV, Haluska FG, Kruse A, Macrae S, Nelson M, Canning C, Lowy I, Korman A, Lautz D, Russell S, Jaklitsch MT, Ramaiya N, Chen TC, Neuberg D, Allison JP, Mihm MC, Dranoff G (2008) Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci USA 105:3005-3010.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3005-3010
-
-
Hodi, F.S.1
Butler, M.2
Oble, D.A.3
Seiden, M.V.4
Haluska, F.G.5
Kruse, A.6
Macrae, S.7
Nelson, M.8
Canning, C.9
Lowy, I.10
Korman, A.11
Lautz, D.12
Russell, S.13
Jaklitsch, M.T.14
Ramaiya, N.15
Chen, T.C.16
Neuberg, D.17
Allison, J.P.18
Mihm, M.C.19
Dranoff, G.20
more..
-
53
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 19;363(8):711-723.
-
(2010)
N Engl J Med
, vol.19-363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
Van Den Eertwegh, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbé, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
54
-
-
55249083982
-
Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
-
Hofmann MA, Kors C, Audring H, Walden P, Sterry W, Trefzer U (2008) Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma. J Immunother 31:520-527.
-
(2008)
J Immunother
, vol.31
, pp. 520-527
-
-
Hofmann, M.A.1
Kors, C.2
Audring, H.3
Walden, P.4
Sterry, W.5
Trefzer, U.6
-
55
-
-
0034667771
-
Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase
-
Hooijberg E, Ruizendaal JJ, Snijders PJ, Kueter EW, Walboomers JM, Spits H (2000) Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase. J Immunol 165:4239-4245.
-
(2000)
J Immunol
, vol.165
, pp. 4239-4245
-
-
Hooijberg, E.1
Ruizendaal, J.J.2
Snijders, P.J.3
Kueter, E.W.4
Walboomers, J.M.5
Spits, H.6
-
56
-
-
34347395733
-
Trastuzumab - mechanism of action and use in clinical practice
-
Hudis CA (2007) Trastuzumab - mechanism of action and use in clinical practice. N Engl J Med 357:39-51.
-
(2007)
N Engl J Med
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
57
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
Hunder NN, Wallen H, Cao J, Hendricks DW, Reilly JZ, Rodmyre R, Jungbluth A, Gnjatic S, Thompson JA, Yee C (2008) Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med 358:2698-2703.
-
(2008)
N Engl J Med
, vol.358
, pp. 2698-2703
-
-
Hunder, N.N.1
Wallen, H.2
Cao, J.3
Hendricks, D.W.4
Reilly, J.Z.5
Rodmyre, R.6
Jungbluth, A.7
Gnjatic, S.8
Thompson, J.A.9
Yee, C.10
-
58
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
59
-
-
0035903307
-
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells
-
Iellem A, Mariani M, Lang R, Recalde H, Panina-Bordignon P, Sinigaglia F, D'Ambrosio D (2001) Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 194:847-853.
-
(2001)
J Exp Med
, vol.194
, pp. 847-853
-
-
Iellem, A.1
Mariani, M.2
Lang, R.3
Recalde, H.4
Panina-Bordignon, P.5
Sinigaglia, F.6
D'Ambrosio, D.7
-
60
-
-
20144388064
-
A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer
-
Ishikawa A, Motohashi S, Ishikawa E, Fuchida H, Higashino K, Otsuji M, Iizasa T, Nakayama T, Taniguchi M, Fujisawa T (2005) A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 11:1910-1917.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1910-1917
-
-
Ishikawa, A.1
Motohashi, S.2
Ishikawa, E.3
Fuchida, H.4
Higashino, K.5
Otsuji, M.6
Iizasa, T.7
Nakayama, T.8
Taniguchi, M.9
Fujisawa, T.10
-
61
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R (2004) Toll-like receptor control of the adaptive immune responses. Nat Immunol 5:987-995.
-
(2004)
Nat Immunol
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
62
-
-
0035152718
-
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: A phase I trial of safety and immune activation
-
Jaffee EM, Hruban RH, Biedrzycki B, Laheru D, Schepers K, Sauter PR, Goemann M, Coleman J, Grochow L, Donehower RC, Lillemoe KD, O'Reilly S, Abrams RA, Pardoll DM, Cameron JL, Yeo CJ (2001) Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation. J Clin Oncol 19:145-156.
-
(2001)
J Clin Oncol
, vol.19
, pp. 145-156
-
-
Jaffee, E.M.1
Hruban, R.H.2
Biedrzycki, B.3
Laheru, D.4
Schepers, K.5
Sauter, P.R.6
Goemann, M.7
Coleman, J.8
Grochow, L.9
Donehower, R.C.10
Lillemoe, K.D.11
O'Reilly, S.12
Abrams, R.A.13
Pardoll, D.M.14
Cameron, J.L.15
Yeo, C.J.16
-
63
-
-
0029009977
-
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
-
Jiang W, Swiggard WJ, Heufler C, Peng M, Mirza A, Steinman RM, Nussenzweig MC (1995) The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375:151-155.
-
(1995)
Nature
, vol.375
, pp. 151-155
-
-
Jiang, W.1
Swiggard, W.J.2
Heufler, C.3
Peng, M.4
Mirza, A.5
Steinman, R.M.6
Nussenzweig, M.C.7
-
64
-
-
34447121852
-
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF
-
Jinushi M, Nakazaki Y, Dougan M, Carrasco DR, Mihm M, Dranoff G (2007) MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. J Clin Invest 117:1902-1913.
-
(2007)
J Clin Invest
, vol.117
, pp. 1902-1913
-
-
Jinushi, M.1
Nakazaki, Y.2
Dougan, M.3
Carrasco, D.R.4
Mihm, M.5
Dranoff, G.6
-
65
-
-
41149108216
-
Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines
-
Jinushi M, Hodi FS, Dranoff G (2008) Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines. Immunol Rev 222:287-298.
-
(2008)
Immunol Rev
, vol.222
, pp. 287-298
-
-
Jinushi, M.1
Hodi, F.S.2
Dranoff, G.3
-
66
-
-
36148941301
-
Cetuximab for the treatment of colorectal cancer
-
Jonker DJ, O'Callaghan CJ, Karapetis CS, Zalcberg JR, Tu D, Au HJ, Berry SR, Krahn M, Price T, Simes RJ, Tebbutt NC, van Hazel G, Wierzbicki R, Langer C, Moore MJ (2007) Cetuximab for the treatment of colorectal cancer. N Engl J Med 357:2040-2048.
-
(2007)
N Engl J Med
, vol.357
, pp. 2040-2048
-
-
Jonker, D.J.1
O'Callaghan, C.J.2
Karapetis, C.S.3
Zalcberg, J.R.4
Tu, D.5
Au, H.J.6
Berry, S.R.7
Krahn, M.8
Price, T.9
Simes, R.J.10
Tebbutt, N.C.11
Van Hazel, G.12
Wierzbicki, R.13
Langer, C.14
Moore, M.J.15
-
67
-
-
34248149835
-
Principles of adoptive T cell cancer therapy
-
June CH (2007) Principles of adoptive T cell cancer therapy. J Clin Invest 117:1204-1212.
-
(2007)
J Clin Invest
, vol.117
, pp. 1204-1212
-
-
June, C.H.1
-
68
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, Redfern CH, Ferrari AC, Dreicer R, Sims RB, Xu Y, Frohlich MW, Schellhammer PF (2010). Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 363(5):411-422.
-
(2010)
N Engl J Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
Xu, Y.11
Frohlich, M.W.12
Schellhammer, P.F.13
-
69
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-IH) in patients who have failed fludarabine: Results of a large international study
-
Keating MJ, Flinn I, Jain V, Binet JL, Hillmen P, Byrd J, Albitar M, Brettman L, Santabarbara P, Wacker B, Rai KR (2002) Therapeutic role of alemtuzumab (Campath-IH) in patients who have failed fludarabine: results of a large international study. Blood 99:3554-3561.
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
Binet, J.L.4
Hillmen, P.5
Byrd, J.6
Albitar, M.7
Brettman, L.8
Santabarbara, P.9
Wacker, B.10
Rai, K.R.11
-
71
-
-
33750699642
-
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
-
Kershaw MH, Westwood JA, Parker LL, Wang G, Eshhar Z, Mavroukakis SA, White DE, Wunderlich JR, Canevari S, Rogers-Freezer L, Chen CC, Yang JC, Rosenberg SA, Hwu P (2006) A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin Cancer Res 12:6106-6115.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6106-6115
-
-
Kershaw, M.H.1
Westwood, J.A.2
Parker, L.L.3
Wang, G.4
Eshhar, Z.5
Mavroukakis, S.A.6
White, D.E.7
Wunderlich, J.R.8
Canevari, S.9
Rogers-Freezer, L.10
Chen, C.C.11
Yang, J.C.12
Rosenberg, S.A.13
Hwu, P.14
-
72
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
73
-
-
34248223901
-
Cutaneous T-cell lymphoma (CTCL) responses to a TLR9 agonist CPG immunomodulator (CPG 7909), a phase I study
-
Kim Y, Girardi M, McAuley S, Schmalbach T (2004) Cutaneous T-cell lymphoma (CTCL) responses to a TLR9 agonist CPG immunomodulator (CPG 7909), a phase I study. J Clin Oncol22:6600.
-
(2004)
J Clin Oncol
, vol.22
, pp. 6600
-
-
Kim, Y.1
Girardi, M.2
McAuley, S.3
Schmalbach, T.4
-
74
-
-
32944478346
-
Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer
-
Kindler HL, Friberg G, Singh DA, Locker G, Nattam S, Kozloff M, Taber DA, Karrison T, Dachman A, Stadler WM, Vokes EE (2005) Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol 23:8033-8040.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8033-8040
-
-
Kindler, H.L.1
Friberg, G.2
Singh, D.A.3
Locker, G.4
Nattam, S.5
Kozloff, M.6
Taber, D.A.7
Karrison, T.8
Dachman, A.9
Stadler, W.M.10
Vokes, E.E.11
-
75
-
-
0030030347
-
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group Trial EST 1684
-
Kirkwood JM, Strawderman MH, Ernstoff MS, Smith TJ, Borden EC, Blum RH (1996) Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 14:7-17.
-
(1996)
J Clin Oncol
, vol.14
, pp. 7-17
-
-
Kirkwood, J.M.1
Strawderman, M.H.2
Ernstoff, M.S.3
Smith, T.J.4
Borden, E.C.5
Blum, R.H.6
-
76
-
-
22144437688
-
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
-
Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, Palmer DC, Antony PA, Hwang ST, Rosenberg SA, Waldmann TA, Restifo NP (2005) Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci USA 102:9571-9576.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9571-9576
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Torabi-Parizi, P.3
Kerstann, K.4
Cardones, A.R.5
Finkelstein, S.E.6
Palmer, D.C.7
Antony, P.A.8
Hwang, S.T.9
Rosenberg, S.A.10
Waldmann, T.A.11
Restifo, N.P.12
-
77
-
-
0029554401
-
KRN7000, a novel immunomodulator, and its antitumor activities
-
Kobayashi E, Motoki K, Uchida T, Fukushima H, Koezuka Y (1995) KRN7000, a novel immunomodulator, and its antitumor activities. Oncol Res 7:529-534.
-
(1995)
Oncol Res
, vol.7
, pp. 529-534
-
-
Kobayashi, E.1
Motoki, K.2
Uchida, T.3
Fukushima, H.4
Koezuka, Y.5
-
78
-
-
33847384529
-
FOXP3+ regulatory T cells affect the development and progression of hepatocarcino-genesis
-
Kobayashi N, Hiraoka N, Yamagami W, Ojima H, Kanai Y, Kosuge T, Nakajima A, Hirohashi S (2007) FOXP3+ regulatory T cells affect the development and progression of hepatocarcino-genesis. Clin Cancer Res 13:902-911.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 902-911
-
-
Kobayashi, N.1
Hiraoka, N.2
Yamagami, W.3
Ojima, H.4
Kanai, Y.5
Kosuge, T.6
Nakajima, A.7
Hirohashi, S.8
-
79
-
-
0025678601
-
Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients
-
Kolb HJ, Mittermuller J, Clemm C, Holler E, Ledderose G, Brehm G, Heim M, Wilmanns W (1990) Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients. Blood 76:2462-2465.
-
(1990)
Blood
, vol.76
, pp. 2462-2465
-
-
Kolb, H.J.1
Mittermuller, J.2
Clemm, C.3
Holler, E.4
Ledderose, G.5
Brehm, G.6
Heim, M.7
Wilmanns, W.8
-
80
-
-
1542267219
-
Graft-versus-leukemia reactions in allogeneic chimeras
-
Kolb HJ, Schmid C, Barrett AJ, Schendel DJ (2004) Graft-versus-leukemia reactions in allogeneic chimeras. Blood 103:767-776.
-
(2004)
Blood
, vol.103
, pp. 767-776
-
-
Kolb, H.J.1
Schmid, C.2
Barrett, A.J.3
Schendel, D.J.4
-
82
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
Krieg AM (2006) Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 5:471-484.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 471-484
-
-
Krieg, A.M.1
-
83
-
-
33646440024
-
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
-
Lamers CH, Sleijfer S, Vulto AG, Kruit WH, Kliffen M, Debets R, Gratama JW, Stoter G, Oosterwijk E (2006) Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol 24:e20-e22.
-
(2006)
J Clin Oncol
, vol.24
, pp. e20-e22
-
-
Lamers, C.H.1
Sleijfer, S.2
Vulto, A.G.3
Kruit, W.H.4
Kliffen, M.5
Debets, R.6
Gratama, J.W.7
Stoter, G.8
Oosterwijk, E.9
-
84
-
-
21144457435
-
Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs
-
Lans TE, Grunhagen DJ, de Wilt JH, van Geel AN, Eggermont AM (2005) Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs. Ann Surg Oncol 12:406-411.
-
(2005)
Ann Surg Oncol
, vol.12
, pp. 406-411
-
-
Lans, T.E.1
Grunhagen, D.J.2
De Wilt, J.H.3
Van Geel, A.N.4
Eggermont, A.M.5
-
85
-
-
35948987594
-
Phase I trial of toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non Hodgkin’s lymphoma
-
Leonard JP, Link BK, Emmanouilides C, Gregory SA, Weisdorf D, Andrey J, Hainsworth J, Sparano JA, Tsai DE, Horning S, Krieg AM, Weiner GJ (2007) Phase I trial of toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non Hodgkin’s lymphoma. Clin Cancer Res 13:6168-6174.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6168-6174
-
-
Leonard, J.P.1
Link, B.K.2
Emmanouilides, C.3
Gregory, S.A.4
Weisdorf, D.5
Rey, J.6
Hainsworth, J.7
Sparano, J.A.8
Tsai, D.E.9
Horning, S.10
Krieg, A.M.11
Weiner, G.J.12
-
86
-
-
17444403242
-
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
-
Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM (2005) Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 7:301-311.
-
(2005)
Cancer Cell
, vol.7
, pp. 301-311
-
-
Li, S.1
Schmitz, K.R.2
Jeffrey, P.D.3
Wiltzius, J.J.4
Kussie, P.5
Ferguson, K.M.6
-
87
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin WW, Karin M (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117:1175-1183.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
88
-
-
0036240637
-
T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H
-
Liu H, Ye H, Ruskone-Fourmestraux A, De Jong D, Pileri S, Thiede C, Lavergne A, Boot H, Caletti G, Wundisch T, Molina T, Taal BG, Elena S, Thomas T, Zinzani PL, Neubauer A, Stolte M, Hamoudi RA, Dogan A, Isaacson PG, Du MQ (2002) T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology 122:1286-1294.
-
(2002)
Pylori Eradication. Gastroenterology
, vol.122
, pp. 1286-1294
-
-
Liu, H.1
Ye, H.2
Ruskone-Fourmestraux, A.3
De Jong, D.4
Pileri, S.5
Thiede, C.6
Lavergne, A.7
Boot, H.8
Caletti, G.9
Wundisch, T.10
Molina, T.11
Taal, B.G.12
Elena, S.13
Thomas, T.14
Zinzani, P.L.15
Neubauer, A.16
Stolte, M.17
Hamoudi, R.A.18
Dogan, A.19
Isaacson, P.G.20
Du, M.Q.21
more..
-
89
-
-
41149173311
-
The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer
-
Lynch DH (2008) The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer. Immunol Rev 222:277-286.
-
(2008)
Immunol Rev
, vol.222
, pp. 277-286
-
-
Lynch, D.H.1
-
90
-
-
33750940238
-
Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma
-
Mackensen A, Meidenbauer N, Vogl S, Laumer M, Berger J, Andreesen R (2006) Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma. J Clin Oncol 24:5060-5069.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5060-5069
-
-
Mackensen, A.1
Meidenbauer, N.2
Vogl, S.3
Laumer, M.4
Berger, J.5
Reesen, R.6
-
91
-
-
23044463870
-
Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice
-
Mahnke K, Qian Y, Fondel S, Brueck J, Becker C, Enk AH (2005) Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice. Cancer Res 65:7007-7012.
-
(2005)
Cancer Res
, vol.65
, pp. 7007-7012
-
-
Mahnke, K.1
Qian, Y.2
Fondel, S.3
Brueck, J.4
Becker, C.5
Enk, A.H.6
-
92
-
-
34247504608
-
Depletion of CD4+ CD25+ human regulatory T cells in vivo: Kinetics of Treg depletion and alterations in immune functions in vivo and in vitro
-
Mahnke K, Schonfeld K, Fondel S, Ring S, Karakhanova S, Wiedemeyer K, Bedke T, Johnson TS, Storn V, Schallenberg S, Enk AH (2007) Depletion of CD4+ CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro. Int J Cancer 120:2723-2733.
-
(2007)
Int J Cancer
, vol.120
, pp. 2723-2733
-
-
Mahnke, K.1
Schonfeld, K.2
Fondel, S.3
Ring, S.4
Karakhanova, S.5
Wiedemeyer, K.6
Bedke, T.7
Johnson, T.S.8
Storn, V.9
Schallenberg, S.10
Enk, A.H.11
-
93
-
-
4344596051
-
Alpha-type-1 polarized dendritic cells: A novel immunization tool with optimized CTL-inducing activity
-
Mailliard RB, Wankowicz-Kalinska A, Cai Q, Wesa A, Hilkens CM, Kapsenberg ML, Kirkwood JM, Storkus WJ, Kalinski P (2004) Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res 64:5934-5937.
-
(2004)
Cancer Res
, vol.64
, pp. 5934-5937
-
-
Mailliard, R.B.1
Wankowicz-Kalinska, A.2
Cai, Q.3
Wesa, A.4
Hilkens, C.M.5
Kapsenberg, M.L.6
Kirkwood, J.M.7
Storkus, W.J.8
Kalinski, P.9
-
94
-
-
34248185263
-
Schmalbach T, Al-Adhami M
-
Manegold C, Leichman G, Gravenor D, Woytowitz D, Mezger J, Albert G, Schmalbach T, Al-Adhami M (2005) Addition of CpG 7909 to taxane/platinum regimen for first-line treatment of unresectable NSCLC improves objective response in phase II clinical trial [abstract]. Eur J Cancer 3:326.
-
(2005)
Eur J Cancer
, vol.3
, pp. 326
-
-
Manegold, C.1
Leichman, G.2
Gravenor, D.3
Woytowitz, D.4
Mezger, J.5
Albert, G.6
-
95
-
-
33845574852
-
The therapeutic use of rituximab in non-Hodgkin’s lymphoma
-
Marcus R, Hagenbeek A (2007) The therapeutic use of rituximab in non-Hodgkin’s lymphoma. Eur J Haematol Suppl (67):5-14.
-
(2007)
Eur J Haematol
, Issue.67
, pp. 5-14
-
-
Marcus, R.1
Hagenbeek, A.2
-
96
-
-
0042922810
-
Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming
-
MartIn-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, Lanzavecchia A, Sallusto F (2003) Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 198:615-621.
-
(2003)
J Exp Med
, vol.198
, pp. 615-621
-
-
Martin-Fontecha, A.1
Sebastiani, S.2
Hopken, U.E.3
Uguccioni, M.4
Lipp, M.5
Lanzavecchia, A.6
Sallusto, F.7
-
97
-
-
13744251436
-
Systemic therapy for colorectal cancer
-
Meyerhardt JA, Mayer RJ (2005) Systemic therapy for colorectal cancer. N Engl J Med 352:476-487.
-
(2005)
N Engl J Med
, vol.352
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
98
-
-
20444453277
-
Delayed disease progression after allogeneic cell vaccination in hormone-resistant prostate cancer and correlation with immunologic variables
-
Michael A, Ball G, Quatan N, Wushishi F, Russell N, Whelan J, Chakraborty P, Leader D, Whelan M, Pandha H (2005) Delayed disease progression after allogeneic cell vaccination in hormone-resistant prostate cancer and correlation with immunologic variables. Clin Cancer Res11:4469-4478.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4469-4478
-
-
Michael, A.1
Ball, G.2
Quatan, N.3
Wushishi, F.4
Russell, N.5
Whelan, J.6
Chakraborty, P.7
Leader, D.8
Whelan, M.9
Pandha, H.10
-
99
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Holmes FA, Cobleigh MA, Marcom PK, Fehrenbacher L, Dickler M, Overmoyer BA, Reimann JD, Sing AP, Langmuir V, Rugo HS (2005) Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 23:792-799.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
Cobleigh, M.A.4
Marcom, P.K.5
Fehrenbacher, L.6
Dickler, M.7
Overmoyer, B.A.8
Reimann, J.D.9
Sing, A.P.10
Langmuir, V.11
Rugo, H.S.12
-
100
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, Royal RE, Topalian SL, Kammula US, Restifo NP, Zheng Z, Nahvi A, de Vries CR, Rogers-Freezer LJ, Mavroukakis SA, Rosenberg SA (2006) Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314:126-129.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
Zheng, Z.11
Nahvi, A.12
De Vries, C.R.13
Rogers-Freezer, L.J.14
Mavroukakis, S.A.15
Rosenberg, S.A.16
-
101
-
-
33750709275
-
A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer
-
Motohashi S, Ishikawa A, Ishikawa E, Otsuji M, Iizasa T, Hanaoka H, Shimizu N, Horiguchi S, Okamoto Y, Fujii S, Taniguchi M, Fujisawa T, Nakayama T (2006) A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 12:6079-6086.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6079-6086
-
-
Motohashi, S.1
Ishikawa, A.2
Ishikawa, E.3
Otsuji, M.4
Iizasa, T.5
Hanaoka, H.6
Shimizu, N.7
Horiguchi, S.8
Okamoto, Y.9
Fujii, S.10
Taniguchi, M.11
Fujisawa, T.12
Nakayama, T.13
-
102
-
-
0036138580
-
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
Motzer RJ, Bacik J, Murphy BA, Russo P, Mazumdar M (2002) Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 20:289-296.
-
(2002)
J Clin Oncol
, vol.20
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.A.3
Russo, P.4
Mazumdar, M.5
-
103
-
-
42949157368
-
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
-
Musolino A, Naldi N, Bortesi B, Pezzuolo D, Capelletti M, Missale G, Laccabue D, Zerbini A, Camisa R, Bisagni G, Neri TM, Ardizzoni A (2008) Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 26:1789-1796.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1789-1796
-
-
Musolino, A.1
Naldi, N.2
Bortesi, B.3
Pezzuolo, D.4
Capelletti, M.5
Missale, G.6
Laccabue, D.7
Zerbini, A.8
Camisa, R.9
Bisagni, G.10
Neri, T.M.11
Ardizzoni, A.12
-
104
-
-
0345447557
-
Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
-
Nair S, McLaughlin C, Weizer A, Su Z, Boczkowski D, Dannull J, Vieweg J, Gilboa E (2003)Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol 171:6275-6282.
-
(2003)
J Immunol
, vol.171
, pp. 6275-6282
-
-
Nair, S.1
McLaughlin, C.2
Weizer, A.3
Su, Z.4
Boczkowski, D.5
Dannull, J.6
Vieweg, J.7
Gilboa, E.8
-
105
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A (2005) Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 6:769-776.
-
(2005)
Nat Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
106
-
-
0942276861
-
Therapeutic activation of Valpha24+ Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
-
Nieda M, Okai M, Tazbirkova A, Lin H, Yamaura A, Ide K, Abraham R, Juji T, Macfarlane DJ, Nicol AJ (2004) Therapeutic activation of Valpha24+ Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity. Blood 103:383-389.
-
(2004)
Blood
, vol.103
, pp. 383-389
-
-
Nieda, M.1
Okai, M.2
Tazbirkova, A.3
Lin, H.4
Yamaura, A.5
Ide, K.6
Abraham, R.7
Juji, T.8
Macfarlane, D.J.9
Nicol, A.J.10
-
107
-
-
36849035139
-
Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): A novel strategy for the treatment of melanoma and other malignancies
-
O'Day SJ, Hamid O, Urba WJ (2007) Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 110:2614-2627.
-
(2007)
Cancer
, vol.110
, pp. 2614-2627
-
-
O'Day, S.J.1
Hamid, O.2
Urba, W.J.3
-
108
-
-
4944223122
-
Manipulating dendritic cell biology for the active immunotherapy of cancer
-
O'Neill DW, Adams S, Bhardwaj N (2004) Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood 104:2235-2246.
-
(2004)
Blood
, vol.104
, pp. 2235-2246
-
-
O'Neill, D.W.1
Adams, S.2
Bhardwaj, N.3
-
109
-
-
33947265424
-
Adoptive transfer of chimeric antigen receptor redirected cytolytic T lymphocyte clones in patients with neuroblastoma
-
Park JR, Digiusto DL, Slovak M, Wright C, Naranjo A, Wagner J, Meechoovet HB, Bautista C, Chang WC, Ostberg JR, Jensen MC (2007) Adoptive transfer of chimeric antigen receptor redirected cytolytic T lymphocyte clones in patients with neuroblastoma. Mol Ther 15:825-833.
-
(2007)
Mol Ther
, vol.15
, pp. 825-833
-
-
Park, J.R.1
Digiusto, D.L.2
Slovak, M.3
Wright, C.4
Naranjo, A.5
Wagner, J.6
Meechoovet, H.B.7
Bautista, C.8
Chang, W.C.9
Ostberg, J.R.10
Jensen, M.C.11
-
110
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin55:74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
111
-
-
34247389227
-
Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma
-
Pashenkov M, Goess G, Wagner C, Hormann M, Jandl T, Moser A, Britten CM, Smolle J, Koller S, Mauch C, Tantcheva-Poor I, Grabbe S, Loquai C, Esser S, Franckson T, Schneeberger A, Haarmann C, Krieg AM, Stingl G, Wagner SN (2006) Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma. J Clin Oncol 24:5716-5724.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5716-5724
-
-
Pashenkov, M.1
Goess, G.2
Wagner, C.3
Hormann, M.4
Jandl, T.5
Moser, A.6
Britten, C.M.7
Smolle, J.8
Koller, S.9
Mauch, C.10
Tantcheva-Poor, I.11
Grabbe, S.12
Loquai, C.13
Esser, S.14
Franckson, T.15
Schneeberger, A.16
Haarmann, C.17
Krieg, A.M.18
Stingl, G.19
Wagner, S.N.20
more..
-
112
-
-
42249097689
-
OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection
-
Piconese S, Valzasina B, Colombo MP (2008) OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection. J Exp Med 205:825-839.
-
(2008)
J Exp Med
, vol.205
, pp. 825-839
-
-
Piconese, S.1
Valzasina, B.2
Colombo, M.P.3
-
113
-
-
33646876477
-
Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity
-
Ramirez-Montagut T, Chow A, Hirschhorn-Cymerman D, Terwey TH, Kochman AA, Lu S, Miles RC, Sakaguchi S, Houghton AN, van den Brink MR (2006) Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity. J Immunol 176:6434-6442.
-
(2006)
J Immunol
, vol.176
, pp. 6434-6442
-
-
Ramirez-Montagut, T.1
Chow, A.2
Hirschhorn-Cymerman, D.3
Terwey, T.H.4
Kochman, A.A.5
Lu, S.6
Miles, R.C.7
Sakaguchi, S.8
Houghton, A.N.9
Van Den Brink, M.R.10
-
114
-
-
0035398021
-
Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
-
Robert F, Ezekiel MP, Spencer SA, Meredith RF, Bonner JA, Khazaeli MB, Saleh MN, Carey D, LoBuglio AF, Wheeler RH, Cooper MR, Waksal HW (2001) Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J Clin Oncol 19:3234-3243.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3234-3243
-
-
Robert, F.1
Ezekiel, M.P.2
Spencer, S.A.3
Meredith, R.F.4
Bonner, J.A.5
Khazaeli, M.B.6
Saleh, M.N.7
Carey, D.8
Lobuglio, A.F.9
Wheeler, R.H.10
Cooper, M.R.11
Waksal, H.W.12
-
115
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, O'Day S, Md JW, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH Jr, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD (2011)Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med30;364(26):2517-2526.
-
(2011)
N Engl J Med
, vol.30-364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Md, J.W.5
Garbe, C.6
Lebbe, C.7
Baurain, J.F.8
Testori, A.9
Grob, J.J.10
Davidson, N.11
Richards, J.12
Maio, M.13
Hauschild, A.14
Miller, W.H.15
Gascon, P.16
Lotem, M.17
Harmankaya, K.18
Ibrahim, R.19
Francis, S.20
Chen, T.T.21
Humphrey, R.22
Hoos, A.23
Wolchok, J.D.24
more..
-
116
-
-
0029038217
-
Eradication of Helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue
-
Roggero E, Zucca E, Pinotti G, Pascarella A, Capella C, Savio A, Pedrinis E, Paterlini A, Venco A, Cavalli F (1995) Eradication of Helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue. Ann Intern Med 122:767-769.
-
(1995)
Ann Intern Med
, vol.122
, pp. 767-769
-
-
Roggero, E.1
Zucca, E.2
Pinotti, G.3
Pascarella, A.4
Capella, C.5
Savio, A.6
Pedrinis, E.7
Paterlini, A.8
Venco, A.9
Cavalli, F.10
-
117
-
-
20344385033
-
Dendritic cell fusion vaccines for cancer immunotherapy
-
Rosenblatt J, Kufe D, Avigan D (2005) Dendritic cell fusion vaccines for cancer immunotherapy. Expert Opin Biol Ther 5:703-715.
-
(2005)
Expert Opin Biol Ther
, vol.5
, pp. 703-715
-
-
Rosenblatt, J.1
Kufe, D.2
Avigan, D.3
-
118
-
-
33947533150
-
Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: A systematic review prepared for the U.S. Preventive Services Task Force
-
Rostom A, Dube C, Lewin G, Tsertsvadze A, Barrowman N, Code C, Sampson M, Moher D (2007) Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force. Ann Intern Med 146:376-389.
-
(2007)
Ann Intern Med
, vol.146
, pp. 376-389
-
-
Rostom, A.1
Dube, C.2
Lewin, G.3
Tsertsvadze, A.4
Barrowman, N.5
Code, C.6
Sampson, M.7
Moher, D.8
-
119
-
-
33645325115
-
Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase III trial of the DC study group of the DeCOG
-
Schadendorf D, Ugurel S, Schuler-Thurner B, Nestle FO, Enk A, Brocker EB, Grabbe S, Rittgen W, Edler L, Sucker A, Zimpfer-Rechner C, Berger T, Kamarashev J, Burg G, Jonuleit H, Tuttenberg A, Becker JC, Keikavoussi P, Kampgen E, Schuler G (2006) Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG. Ann Oncol 17:563-570.
-
(2006)
Ann Oncol
, vol.17
, pp. 563-570
-
-
Schadendorf, D.1
Ugurel, S.2
Schuler-Thurner, B.3
Nestle, F.O.4
Enk, A.5
Brocker, E.B.6
Grabbe, S.7
Rittgen, W.8
Edler, L.9
Sucker, A.10
Zimpfer-Rechner, C.11
Berger, T.12
Kamarashev, J.13
Burg, G.14
Jonuleit, H.15
Tuttenberg, A.16
Becker, J.C.17
Keikavoussi, P.18
Kampgen, E.19
Schuler, G.20
more..
-
120
-
-
79957831345
-
Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
-
Schwartzentruber DJ, Lawson DH, Richards JM, Conry RM, Miller DM, Treisman J, Gailani F, Riley L, Conlon K, Pockaj B, Kendra KL, White RL, Gonzalez R, Kuzel TM, Curti B, Leming PD, Whitman ED, Balkissoon J, Reintgen DS, Kaufman H, Marincola FM, Merino MJ, Rosenberg SA, Choyke P, Vena D, Hwu P (2011) gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med 2;364(22):2119-2227.
-
(2011)
N Engl J Med
, vol.2-364
, Issue.22
, pp. 2119-2227
-
-
Schwartzentruber, D.J.1
Lawson, D.H.2
Richards, J.M.3
Conry, R.M.4
Miller, D.M.5
Treisman, J.6
Gailani, F.7
Riley, L.8
Conlon, K.9
Pockaj, B.10
Kendra, K.L.11
White, R.L.12
Gonzalez, R.13
Kuzel, T.M.14
Curti, B.15
Leming, P.D.16
Whitman, E.D.17
Balkissoon, J.18
Reintgen, D.S.19
Kaufman, H.20
Marincola, F.M.21
Merino, M.J.22
Rosenberg, S.A.23
Choyke, P.24
Vena, D.25
Hwu, P.26
more..
-
122
-
-
79958264390
-
Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma
-
Schuster SJ, Neelapu SS, Gause BL, Janik JE, Muggia FM, Gockerman JP, Winter JN, Flowers CR, Nikcevich DA, Sotomayor EM, McGaughey DS, Jaffe ES, Chong EA, Reynolds CW, Berry DA, Santos CF, Popa MA, McCord AM, Kwak LW (2011) Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J Clin Oncol 10;29(20):2787-2794.
-
(2011)
J Clin Oncol 10
, vol.29
, Issue.20
, pp. 2787-2794
-
-
Schuster, S.J.1
Neelapu, S.S.2
Gause, B.L.3
Janik, J.E.4
Muggia, F.M.5
Gockerman, J.P.6
Winter, J.N.7
Flowers, C.R.8
Nikcevich, D.A.9
Sotomayor, E.M.10
McGaughey, D.S.11
Jaffe, E.S.12
Chong, E.A.13
Reynolds, C.W.14
Berry, D.A.15
Santos, C.F.16
Popa, M.A.17
McCord, A.M.18
Kwak, L.W.19
-
123
-
-
0034104375
-
Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
-
Shan D, Ledbetter JA, Press OW (2000) Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells. Cancer Immunol Immunother 48:673-683.
-
(2000)
Cancer Immunol Immunother
, vol.48
, pp. 673-683
-
-
Shan, D.1
Ledbetter, J.A.2
Press, O.W.3
-
124
-
-
0034565464
-
Intravesical Bacillus Calmette-Guerin in Ta and T1 bladder cancer
-
Shelley MD, Court JB, Kynaston H, Wilt TJ, Fish RG, Mason M (2000) Intravesical Bacillus Calmette-Guerin in Ta and T1 bladder cancer. Cochrane Database Syst Rev CD001986.
-
(2000)
Cochrane Database Syst Rev CD001986
-
-
Shelley, M.D.1
Court, J.B.2
Kynaston, H.3
Wilt, T.J.4
Fish, R.G.5
Mason, M.6
-
125
-
-
33745219416
-
Phase I/II trial of an allogeneic cellular immunotherapy in hormone-naive prostate cancer
-
Simons JW, Carducci MA, Mikhak B, Lim M, Biedrzycki B, Borellini F, Clift SM, Hege KM, Ando DG, Piantadosi S, Mulligan R, Nelson WG (2006) Phase I/II trial of an allogeneic cellular immunotherapy in hormone-naive prostate cancer. Clin Cancer Res 12:3394-3401.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3394-3401
-
-
Simons, J.W.1
Carducci, M.A.2
Mikhak, B.3
Lim, M.4
Biedrzycki, B.5
Borellini, F.6
Clift, S.M.7
Hege, K.M.8
Ando, D.G.9
Piantadosi, S.10
Mulligan, R.11
Nelson, W.G.12
-
126
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, Fleming T, Eiermann W, Wolter J, Pegram M, Baselga J, Norton L (2001) Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
127
-
-
33646244160
-
Immunity to melanoma antigens: From selftolerance to immunotherapy
-
Slingluff CL Jr., Chianese-Bullock KA, Bullock TN, Grosh WW, Mullins DW, Nichols L, Olson W, Petroni G, Smolkin M, Engelhard VH (2006) Immunity to melanoma antigens: from selftolerance to immunotherapy. Adv Immunol 90:243-295.
-
(2006)
Adv Immunol
, vol.90
, pp. 243-295
-
-
Slingluff, C.L.1
Chianese-Bullock, K.A.2
Bullock, T.N.3
Grosh, W.W.4
Mullins, D.W.5
Nichols, L.6
Olson, W.7
Petroni, G.8
Smolkin, M.9
Engelhard, V.H.10
-
128
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, Verjee SS, Jones LA, Hershberg RM (2006) Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 24:3089-3094.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
Redfern, C.H.4
Nemunaitis, J.J.5
Valone, F.H.6
Verjee, S.S.7
Jones, L.A.8
Hershberg, R.M.9
-
129
-
-
0036533337
-
NKT cells - conductors of tumor immunity?
-
Smyth MJ, Crowe NY, Hayakawa Y, Takeda K, Yagita H, Godfrey DI (2002) NKT cells - conductors of tumor immunity? Curr Opin Immunol 14:165-171.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 165-171
-
-
Smyth, M.J.1
Crowe, N.Y.2
Hayakawa, Y.3
Takeda, K.4
Yagita, H.5
Godfrey, D.I.6
-
130
-
-
0032573225
-
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
-
Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC, Hodi FS, Liebster L, Lam P, Mentzer S, Singer S, Tanabe KK, Cosimi AB, Duda R, Sober A, Bhan A, Daley J, Neuberg D, Parry G, Rokovich J, Richards L, Drayer J, Berns A, Clift S, Cohen LK, Mulligan RC, Dranoff G (1998) Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci USA 95:13141-13146.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13141-13146
-
-
Soiffer, R.1
Lynch, T.2
Mihm, M.3
Jung, K.4
Rhuda, C.5
Schmollinger, J.C.6
Hodi, F.S.7
Liebster, L.8
Lam, P.9
Mentzer, S.10
Singer, S.11
Tanabe, K.K.12
Cosimi, A.B.13
Duda, R.14
Sober, A.15
Bhan, A.16
Daley, J.17
Neuberg, D.18
Parry, G.19
Rokovich, J.20
Richards, L.21
Drayer, J.22
Berns, A.23
Clift, S.24
Cohen, L.K.25
Mulligan, R.C.26
Dranoff, G.27
more..
-
131
-
-
13944260898
-
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
-
Sporri R, Reis e Sousa C (2005) Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol 6:163-170.
-
(2005)
Nat Immunol
, vol.6
, pp. 163-170
-
-
Sporri, R.1
Reis E Sousa, C.2
-
132
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G, Lynch PM, Phillips RK, Wallace MH, Hawk E, Gordon GB, Wakabayashi N, Saunders B, Shen Y, Fujimura T, Su LK, Levin B (2000) The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 342:1946-1952.
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
Wakabayashi, N.7
Saunders, B.8
Shen, Y.9
Fujimura, T.10
Su, L.K.11
Levin, B.12
-
133
-
-
2942592429
-
Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40
-
Sugamura K, Ishii N, Weinberg AD (2004) Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40. Nat Rev Immunol 4:420-431.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 420-431
-
-
Sugamura, K.1
Ishii, N.2
Weinberg, A.D.3
-
134
-
-
0008486660
-
Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation
-
Sunada H, Magun BE, Mendelsohn J, MacLeod CL (1986) Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation. Proc Natl Acad Sci USA 83:3825-3829.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 3825-3829
-
-
Sunada, H.1
Magun, B.E.2
Mendelsohn, J.3
Macleod, C.L.4
-
135
-
-
20444492338
-
Bacillus calmette-guerin versus chemotherapy for the intravesical treatment of patients with carcinoma in situ of the bladder: A meta-analysis of the published results of randomized clinical trials
-
Discussion
-
Sylvester RJ, van der Meijden AP, Witjes JA, Kurth K (2005) Bacillus calmette-guerin versus chemotherapy for the intravesical treatment of patients with carcinoma in situ of the bladder: a meta-analysis of the published results of randomized clinical trials. J Urol 174:86-91; Discussion 91-82.
-
(2005)
J Urol
, vol.174
, pp. 86-91
-
-
Sylvester, R.J.1
Van Der Meijden, A.P.2
Witjes, J.A.3
Kurth, K.4
-
136
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH (1995) Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541-547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
137
-
-
0141449956
-
Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production
-
Topp MS, Riddell SR, Akatsuka Y, Jensen MC, Blattman JN, Greenberg PD (2003) Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production. J Exp Med 198:947-955.
-
(2003)
J Exp Med
, vol.198
, pp. 947-955
-
-
Topp, M.S.1
Riddell, S.R.2
Akatsuka, Y.3
Jensen, M.C.4
Blattman, J.N.5
Greenberg, P.D.6
-
138
-
-
0036177671
-
Cyclooxygenase-2: A therapeutic target
-
Turini ME, DuBois RN (2002) Cyclooxygenase-2: a therapeutic target. Annu Rev Med 53:35-57.
-
(2002)
Annu Rev Med
, vol.53
, pp. 35-57
-
-
Turini, M.E.1
Dubois, R.N.2
-
139
-
-
37349014075
-
Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer
-
Uchida T, Horiguchi S, Tanaka Y, Yamamoto H, Kunii N, Motohashi S, Taniguchi M, Nakayama T, Okamoto Y (2008) Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer. Cancer Immunol Immunother 57:337-345.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 337-345
-
-
Uchida, T.1
Horiguchi, S.2
Tanaka, Y.3
Yamamoto, H.4
Kunii, N.5
Motohashi, S.6
Taniguchi, M.7
Nakayama, T.8
Okamoto, Y.9
-
140
-
-
34447306848
-
Trastuzumab: Mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer
-
Valabrega G, Montemurro F, Aglietta M (2007) Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer. Ann Oncol 18:977-984.
-
(2007)
Ann Oncol
, vol.18
, pp. 977-984
-
-
Valabrega, G.1
Montemurro, F.2
Aglietta, M.3
-
141
-
-
34547475142
-
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming
-
Valmori D, Souleimanian NE, Tosello V, Bhardwaj N, Adams S, O'Neill D, Pavlick A, Escalon JB, Cruz CM, Angiulli A, Angiulli F, Mears G, Vogel SM, Pan L, Jungbluth AA, Hoffmann EW, Venhaus R, Ritter G, Old LJ, Ayyoub M (2007) Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming. Proc Natl Acad Sci USA 104:8947-8952.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8947-8952
-
-
Valmori, D.1
Souleimanian, N.E.2
Tosello, V.3
Bhardwaj, N.4
Adams, S.5
O'Neill, D.6
Pavlick, A.7
Escalon, J.B.8
Cruz, C.M.9
Angiulli, A.10
Angiulli, F.11
Mears, G.12
Vogel, S.M.13
Pan, L.14
Jungbluth, A.A.15
Hoffmann, E.W.16
Venhaus, R.17
Ritter, G.18
Old, L.J.19
Ayyoub, M.20
more..
-
142
-
-
26644448965
-
Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model
-
Vambutas A, DeVoti J, Nouri M, Drijfhout JW, Lipford GB, Bonagura VR, van der Burg SH, Melief CJ (2005) Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model. Vaccine 23:5271-5280.
-
(2005)
Vaccine
, vol.23
, pp. 5271-5280
-
-
Vambutas, A.1
Devoti, J.2
Nouri, M.3
Drijfhout, J.W.4
Lipford, G.B.5
Bonagura, V.R.6
Van Der Burg, S.H.7
Melief, C.J.8
-
143
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
-
Van Cutsem E, Peeters M, Siena S, Humblet Y, Hendlisz A, Neyns B, Canon JL, Van Laethem JL, Maurel J, Richardson G, Wolf M, Amado RG (2007) Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 25:1658-1664.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
Humblet, Y.4
Hendlisz, A.5
Neyns, B.6
Canon, J.L.7
Van Laethem, J.L.8
Maurel, J.9
Richardson, G.10
Wolf, M.11
Amado, R.G.12
-
144
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
van Elsas A, Hurwitz AA, Allison JP (1999) Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med190:355-366.
-
(1999)
J Exp Med
, vol.190
, pp. 355-366
-
-
Van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
145
-
-
41649084839
-
Treatment of vulvar intraepithelial neoplasia with topical imiquimod
-
van Seters M, van Beurden M, ten Kate FJ, Beckmann I, Ewing PC, Eijkemans MJ, Kagie MJ, Meijer CJ, Aaronson NK, Kleinjan A, Heijmans-Antonissen C, Zijlstra FJ, Burger MP, Helmerhorst TJ (2008) Treatment of vulvar intraepithelial neoplasia with topical imiquimod. N Engl J Med 358:1465-1473.
-
(2008)
N Engl J Med
, vol.358
, pp. 1465-1473
-
-
Van Seters, M.1
Van Beurden, M.2
Ten Kate, F.J.3
Beckmann, I.4
Ewing, P.C.5
Eijkemans, M.J.6
Kagie, M.J.7
Meijer, C.J.8
Aaronson, N.K.9
Kleinjan, A.10
Heijmans-Antonissen, C.11
Zijlstra, F.J.12
Burger, M.P.13
Helmerhorst, T.J.14
-
146
-
-
0035412401
-
Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
-
Van Tendeloo VF, Ponsaerts P, Lardon F, Nijs G, Lenjou M, Van Broeckhoven C, Van Bockstaele DR, Berneman ZN (2001) Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 98:49-56.
-
(2001)
Blood
, vol.98
, pp. 49-56
-
-
Van Tendeloo, V.F.1
Ponsaerts, P.2
Lardon, F.3
Nijs, G.4
Lenjou, M.5
Van Broeckhoven, C.6
Van Bockstaele, D.R.7
Berneman, Z.N.8
-
147
-
-
21344446543
-
Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies
-
Velayos FS, Terdiman JP, Walsh JM (2005) Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 100:1345-1353.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1345-1353
-
-
Velayos, F.S.1
Terdiman, J.P.2
Walsh, J.M.3
-
148
-
-
33947506186
-
Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody
-
Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, Sullivan P, Mahany JJ, Gallagher M, Kramer A, Green SJ, O'Dwyer PJ, Running KL, Huhn RD, Antonia SJ (2007) Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody. J Clin Oncol 25:876-883.
-
(2007)
J Clin Oncol
, vol.25
, pp. 876-883
-
-
Vonderheide, R.H.1
Flaherty, K.T.2
Khalil, M.3
Stumacher, M.S.4
Bajor, D.L.5
Hutnick, N.A.6
Sullivan, P.7
Mahany, J.J.8
Gallagher, M.9
Kramer, A.10
Green, S.J.11
O'Dwyer, P.J.12
Running, K.L.13
Huhn, R.D.14
Antonia, S.J.15
-
149
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW (1995) Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270:985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
150
-
-
0018764352
-
Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
-
Weiden PL, Flournoy N, Thomas ED, Prentice R, Fefer A, Buckner CD, Storb R (1979) Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N Engl J Med 300:1068-1073.
-
(1979)
N Engl J Med
, vol.300
, pp. 1068-1073
-
-
Weiden, P.L.1
Flournoy, N.2
Thomas, E.D.3
Prentice, R.4
Fefer, A.5
Buckner, C.D.6
Storb, R.7
-
151
-
-
14544301233
-
Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype
-
Weng WK, Czerwinski D, Timmerman J, Hsu FJ, Levy R (2004) Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype. J Clin Oncol 22:4717-4724.
-
(2004)
J Clin Oncol
, vol.22
, pp. 4717-4724
-
-
Weng, W.K.1
Czerwinski, D.2
Timmerman, J.3
Hsu, F.J.4
Levy, R.5
-
152
-
-
0037093241
-
Randomized controlled trial of yttrium-90-labeled ibritumomab tiuxetan radioimmunotherapy versus rituximabimmunotherapy for patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin’s lymphoma
-
Witzig TE, Gordon LI, Cabanillas F, Czuczman MS, Emmanouilides C, Joyce R, Pohlman BL, Bartlett NL, Wiseman GA, Padre N, Grillo-Lopez AJ, Multani P, White CA (2002) Randomized controlled trial of yttrium-90-labeled ibritumomab tiuxetan radioimmunotherapy versus rituximab immunotherapy for patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin’s lymphoma. J Clin Oncol 20:2453-2463.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2453-2463
-
-
Witzig, T.E.1
Gordon, L.I.2
Cabanillas, F.3
Czuczman, M.S.4
Emmanouilides, C.5
Joyce, R.6
Pohlman, B.L.7
Bartlett, N.L.8
Wiseman, G.A.9
Padre, N.10
Grillo-Lopez, A.J.11
Multani, P.12
White, C.A.13
-
153
-
-
28544433483
-
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
-
Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Gastl G, Gunsilius E, Marth C (2005) The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res11:8326-8331.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8326-8331
-
-
Wolf, D.1
Wolf, A.M.2
Rumpold, H.3
Fiegl, H.4
Zeimet, A.G.5
Muller-Holzner, E.6
Deibl, M.7
Gastl, G.8
Gunsilius, E.9
Marth, C.10
-
154
-
-
9144220789
-
Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: A randomized controlled trial
-
Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WH, Yuen ST, Leung SY, Fong DY, Ho J, Ching CK (2004) Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA 291:187-194.
-
(2004)
JAMA
, vol.291
, pp. 187-194
-
-
Wong, B.C.1
Lam, S.K.2
Wong, W.M.3
Chen, J.S.4
Zheng, T.T.5
Feng, R.E.6
Lai, K.C.7
Hu, W.H.8
Yuen, S.T.9
Leung, S.Y.10
Fong, D.Y.11
Ho, J.12
Ching, C.K.13
-
155
-
-
34848900497
-
Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs
-
Wong RM, Scotland RR, Lau RL, Wang C, Korman AJ, Kast WM, Weber JS (2007) Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs. Int Immunol 19:1223-1234.
-
(2007)
Int Immunol
, vol.19
, pp. 1223-1234
-
-
Wong, R.M.1
Scotland, R.R.2
Lau, R.L.3
Wang, C.4
Korman, A.J.5
Kast, W.M.6
Weber, J.S.7
-
156
-
-
33646758868
-
Induction of tumor immunity following allogeneic stem cell transplantation
-
Wu CJ, Ritz J (2006) Induction of tumor immunity following allogeneic stem cell transplantation. Adv Immunol 90:133-173.
-
(2006)
Adv Immunol
, vol.90
, pp. 133-173
-
-
Wu, C.J.1
Ritz, J.2
-
157
-
-
0033559606
-
Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy
-
Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG, Jakobovits A (1999) Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy. Cancer Res 59:1236-1243.
-
(1999)
Cancer Res
, vol.59
, pp. 1236-1243
-
-
Yang, X.D.1
Jia, X.C.2
Corvalan, J.R.3
Wang, P.4
Davis, C.G.5
Jakobovits, A.6
-
158
-
-
0034606276
-
Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of t cell-mediated vitiligo
-
Yee C, Thompson JA, Roche P, Byrd DR, Lee PP, Piepkorn M, Kenyon K, Davis MM, Riddell SR, Greenberg PD (2000) Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo. J Exp Med 192:1637-1644.
-
(2000)
J Exp Med
, vol.192
, pp. 1637-1644
-
-
Yee, C.1
Thompson, J.A.2
Roche, P.3
Byrd, D.R.4
Lee, P.P.5
Piepkorn, M.6
Kenyon, K.7
Davis, M.M.8
Riddell, S.R.9
Greenberg, P.D.10
-
159
-
-
78049515807
-
Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas
-
Younes A, Bartlett NL, Leonard JP, Kennedy DA, Lynch CM, Sievers EL, Forero-Torres A (2010) Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas. N Engl J Med 4;363(19): 1812-1821.
-
(2010)
N Engl J Med 4;363(19)
, pp. 1812-1821
-
-
Younes, A.1
Bartlett, N.L.2
Leonard, J.P.3
Kennedy, D.A.4
Lynch, C.M.5
Sievers, E.L.6
Forero-Torres, A.7
-
160
-
-
0037058993
-
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
-
Yee C, Thompson JA, Byrd D, Riddell SR, Roche P, Celis E, Greenberg PD (2002) Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc Natl Acad Sci USA 99:16168-16173.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16168-16173
-
-
Yee, C.1
Thompson, J.A.2
Byrd, D.3
Riddell, S.R.4
Roche, P.5
Celis, E.6
Greenberg, P.D.7
-
161
-
-
30444443314
-
Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
-
Zhou G, Drake CG, Levitsky HI (2006) Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood 107:628-636.
-
(2006)
Blood
, vol.107
, pp. 628-636
-
-
Zhou, G.1
Drake, C.G.2
Levitsky, H.I.3
|