Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

Cancer Cell

Volumn 7, Issue 4, 2005, Pages 301-311

  Li, Shiqing ^a   Schmitz, Karl R ^a,b   Jeffrey, Philip D ^c,e   Wiltzius, Jed J W ^d   Kussie, Paul ^d   Ferguson, Kathryn M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Grad Grp Biochem Molec Biophys   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT;

ANTIGEN BINDING; ARTICLE; CANCER HORMONE THERAPY; CANCER INHIBITION; CRYSTAL STRUCTURE; DIMERIZATION; DRUG CONFORMATION; DRUG INHIBITION; DRUG STRUCTURE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; STRUCTURE ANALYSIS;

EID: 17444403242     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2005.03.003     Document Type: Article

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