Synthetic cytotoxicity: Digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin

Genetics

Volumn 197, Issue 2, 2014, Pages 611-623

  Li, Xuesong ^a   O'Neil, Nigel J ^a   Moshgabadi, Noushin ^a   Hieter, Philip ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BLEOMYCIN; CAMPTOTHECIN; CASEIN KINASE II; CYCLOHEXIMIDE; FLUOROURACIL; HYDROXYUREA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TEL1 PROTEIN; UNCLASSIFIED DRUG; DNA TOPOISOMERASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE; TEL1 PROTEIN, S CEREVISIAE;

ARTICLE; CAENORHABDITIS ELEGANS; CHROMOSOMAL INSTABILITY; CYTOTOXICITY; DNA DAMAGE; DNA END JOINING REPAIR; EPISTASIS; GENE DELETION; GENE INTERACTION; GENE MUTATION; M PHASE CELL CYCLE CHECKPOINT; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SOMATIC MUTATION; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; ANIMAL; CHEMISTRY; DNA MICROARRAY; DRUG EFFECTS; GENETICS; TELOMERE;

ANIMALS; CAENORHABDITIS ELEGANS; CAMPTOTHECIN; DNA DAMAGE; EPISTASIS, GENETIC; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERE; TOPOISOMERASE I INHIBITORS;

EID: 84902496372     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.114.161307     Document Type: Article

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