Cancer therapy-induced cardiotoxicity: Basic mechanisms and potential cardioprotective therapies

Journal of the American Heart Association

Volumn 3, Issue 2, 2014, Pages

  Hahn, Virginia Shalkey ^a   Lenihan, Daniel J ^c   Ky, Bonnie ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anthracycline cardiotoxicity; Cardio oncology; Cardiotoxicity; Sunitinib cardiotoxicity; Trastuzumab cardiotoxicity

Indexed keywords

ADENYLATE KINASE; ANTHRACYCLINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NEU DIFFERENTIATION FACTOR; RAC1 PROTEIN; RAZOXANE; SORAFENIB; SUNITINIB; THALIDOMIDE; TRASTUZUMAB; ANTINEOPLASTIC AGENT; PROTECTIVE AGENT;

CANCER CHEMOTHERAPY; CANCER THERAPY; CARDIOTOXICITY; DRUG MECHANISM; DYSPNEA; EXERCISE; HEART DISEASE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PROTECTION; HUMAN; HYPERTENSION; LARGE CELL LYMPHOMA; LEFT VENTRICLE REMODELING; LEG EDEMA; MITOCHONDRIAL ENERGY TRANSFER; OXIDATIVE STRESS; PATIENT RISK; PERICYTE; PRIORITY JOURNAL; REVIEW; STRESS; TRANSTHORACIC ECHOCARDIOGRAPHY; ANIMAL; ANTHRACYCLINE CARDIOTOXICITY; CARDIO-ONCOLOGY; CELL PROTECTION; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HEART MUSCLE; KINESIOTHERAPY; METABOLISM; MOLECULARLY TARGETED THERAPY; RISK ASSESSMENT; RISK FACTOR; SIGNAL TRANSDUCTION; SUNITINIB CARDIOTOXICITY; TRASTUZUMAB CARDIOTOXICITY; TREATMENT OUTCOME;

ANTHRACYCLINE CARDIOTOXICITY; CARDIO-ONCOLOGY; CARDIOTOXICITY; SUNITINIB CARDIOTOXICITY; TRASTUZUMAB CARDIOTOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS; CYTOPROTECTION; EXERCISE THERAPY; HEART DISEASES; HUMANS; MOLECULAR TARGETED THERAPY; MYOCARDIUM; PROTECTIVE AGENTS; RISK ASSESSMENT; RISK FACTORS; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 84902445827     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000665     Document Type: Review

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