Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib

Molecular Pharmacology

Volumn 74, Issue 6, 2008, Pages 1722-1728

  Hasinoff, Brian B ^a   Patel, Daywin ^a   O'Hara, Kimberley A ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; RAZOXANE; SUNITINIB;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEART CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYL-COA CARBOXYLASE; ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELLS, CULTURED; HYPOGLYCEMIC AGENTS; INDOLES; L-LACTATE DEHYDROGENASE; METFORMIN; MUSCLE CELLS; OXIDATIVE STRESS; PHENFORMIN; PHOSPHORYLATION; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

EID: 57349174523     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.050104     Document Type: Article

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