메뉴 건너뛰기




Volumn 48, Issue 1, 2009, Pages 9-17

Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; IMATINIB; INTERFERON; PLACEBO; SUNITINIB;

EID: 58149098429     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.1080/02841860802314720     Document Type: Review
Times cited : (284)

References (41)
  • 1
    • 78650874372 scopus 로고    scopus 로고
    • SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
    • Abrams TJ, Lee LB, Murray LJ, Pryer NK, Cherrington JM. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003;2:471-8.
    • (2003) Mol Cancer Ther , vol.2 , pp. 471-478
    • Abrams, T.J.1    Lee, L.B.2    Murray, L.J.3    Pryer, N.K.4    Cherrington, J.M.5
  • 2
    • 0038204144 scopus 로고    scopus 로고
    • SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
    • O'Farrell AM, Abrams TJ, Yuen HA, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003;101:3597-605.
    • (2003) Blood , vol.101 , pp. 3597-3605
    • O'Farrell, A.M.1    Abrams, T.J.2    Yuen, H.A.3
  • 3
    • 12444297983 scopus 로고    scopus 로고
    • The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels
    • Osusky KL, Hallahan DE, Fu A, Ye F, Shyr Y, Geng L. The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels. Angiogenesis 2004;7:225-33.
    • (2004) Angiogenesis , vol.7 , pp. 225-233
    • Osusky, K.L.1    Hallahan, D.E.2    Fu, A.3    Ye, F.4    Shyr, Y.5    Geng, L.6
  • 4
    • 9144274970 scopus 로고    scopus 로고
    • SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
    • Murray LJ, Abrams TJ, Long KR, et al. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003;20:757-66.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 757-766
    • Murray, L.J.1    Abrams, T.J.2    Long, K.R.3
  • 5
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman AJ, Himmelfarb E, Geng L, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003;63:4009-16.
    • (2003) Cancer Res , vol.63 , pp. 4009-4016
    • Schueneman, A.J.1    Himmelfarb, E.2    Geng, L.3
  • 6
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. New Engl J Med 2007;356:115-24.
    • (2007) New Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 7
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006;24:16-24.
    • (2006) J Clin Oncol , vol.24 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 8
    • 33744954585 scopus 로고    scopus 로고
    • Sunitinib in patients with metastatic renal cell carcinoma
    • Motzer RJ, Rini BI, Bukowski RM, et al. Sunitinib in patients with metastatic renal cell carcinoma. JAMA 2006;295:2516-24.
    • (2006) JAMA , vol.295 , pp. 2516-2524
    • Motzer, R.J.1    Rini, B.I.2    Bukowski, R.M.3
  • 9
    • 33749505836 scopus 로고    scopus 로고
    • Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
    • Demetri GD, van Oosterom AT, Garrett CR, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial. Lancet 2006;368:1329-38.
    • (2006) Lancet , vol.368 , pp. 1329-1338
    • Demetri, G.D.1    van Oosterom, A.T.2    Garrett, C.R.3
  • 10
    • 36849023013 scopus 로고    scopus 로고
    • Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
    • Chu TF, Rupnick MA, Kerkela R, et al. Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet 2007;370:2011-9.
    • (2007) Lancet , vol.370 , pp. 2011-2019
    • Chu, T.F.1    Rupnick, M.A.2    Kerkela, R.3
  • 11
    • 58149102548 scopus 로고    scopus 로고
    • Pfizer. Sutent Prescribing Information, updated on 2/07, available at http:/www.pfizer.com/pfizer/download/uspi_sutent.pdf. 2006.
    • Pfizer. Sutent Prescribing Information, updated on 2/07, available at http:/www.pfizer.com/pfizer/download/uspi_sutent.pdf. 2006.
  • 12
    • 58149090694 scopus 로고    scopus 로고
    • NCI, Cancer Therapy Evaluation Program. CTC v 2.0 and common terminology criteria for adverse events criteria V3.0 (CTCAE). Available at http:/ctep.cancer.gov/reporting/ctc.html. 2006.
    • NCI, Cancer Therapy Evaluation Program. CTC v 2.0 and common terminology criteria for adverse events criteria V3.0 (CTCAE). Available at http:/ctep.cancer.gov/reporting/ctc.html. 2006.
  • 14
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997;127:820-6.
    • (1997) Ann Intern Med , vol.127 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 15
    • 58149095486 scopus 로고    scopus 로고
    • Sunitinib in Metastatic Renal Cell Carcinoma (mRCC): Preliminary assessment in an expanded access trial with subpopulation analysis
    • June 20, Chicago, IL;, p. 237s
    • Gore ME, Oudard S, Bjarnason G, Castellano D, Szczylik C, Mainwaring PN, et al. Sunitinib in Metastatic Renal Cell Carcinoma (mRCC): Preliminary assessment in an expanded access trial with subpopulation analysis. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 237s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Gore, M.E.1    Oudard, S.2    Bjarnason, G.3    Castellano, D.4    Szczylik, C.5    Mainwaring, P.N.6
  • 16
    • 58149089168 scopus 로고    scopus 로고
    • Subpopulation analyses in a worldwide treatment-use trial of sunitinib (SU) in GIST patients (pts) with resistance or intolerance to prior imatinib (IM) therapy
    • June 20, Chicago, IL;, p. 550s
    • Reichardt P, Ruka W, Seddon B, Baum CM, Demetri GD. Subpopulation analyses in a worldwide treatment-use trial of sunitinib (SU) in GIST patients (pts) with resistance or intolerance to prior imatinib (IM) therapy. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 550s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Reichardt, P.1    Ruka, W.2    Seddon, B.3    Baum, C.M.4    Demetri, G.D.5
  • 17
    • 42449148017 scopus 로고    scopus 로고
    • Sunitinib as second-line treatment for advanced gastric cancer: Preliminary results from a Phase II study
    • June 20, Chicago, IL;, p. 223s
    • Bang Y, Kang W, Boku N, Chung H, Lanzalone S, Lechuga MJ, et al. Sunitinib as second-line treatment for advanced gastric cancer: Preliminary results from a Phase II study. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 223s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Bang, Y.1    Kang, W.2    Boku, N.3    Chung, H.4    Lanzalone, S.5    Lechuga, M.J.6
  • 18
    • 36749052079 scopus 로고    scopus 로고
    • Efficay and safety of continuous daily sunitinib dosing in previously treated advanced non-small cell lung cancer (NSCLC): Results from a Phase II study
    • June 20, Chicago, IL;, p. 395s
    • Brahmer JR, Novello S, Rosell R, Belani CP, Atkins JN, Gillenwater HH, et al. Efficay and safety of continuous daily sunitinib dosing in previously treated advanced non-small cell lung cancer (NSCLC): Results from a Phase II study. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 395s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Brahmer, J.R.1    Novello, S.2    Rosell, R.3    Belani, C.P.4    Atkins, J.N.5    Gillenwater, H.H.6
  • 19
    • 58149083848 scopus 로고    scopus 로고
    • Continuous daily dosing of sunitinib malate compares favorably with intermittent dosing in patients with advanced GIST
    • June 20, Chicago, IL;, p. 548s
    • George S, Casali PG, LeCesne A, Morgan JA, Pokela J, Quigley MT, et al. Continuous daily dosing of sunitinib malate compares favorably with intermittent dosing in patients with advanced GIST. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 548s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • George, S.1    Casali, P.G.2    LeCesne, A.3    Morgan, J.A.4    Pokela, J.5    Quigley, M.T.6
  • 20
    • 58149102753 scopus 로고    scopus 로고
    • Phase II study of sunitinib in patients with repalpsed or refractory urothelial carcinoma
    • June 20, Chicago, IL;, p. 254s
    • Iasonos A, Riches J, Bajorin DF. Phase II study of sunitinib in patients with repalpsed or refractory urothelial carcinoma. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 254s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Iasonos, A.1    Riches, J.2    Bajorin, D.F.3
  • 21
    • 58149083485 scopus 로고    scopus 로고
    • Efficacy and safety of sunitinib Malate (SU11248, Sutent) in bevacizumab-refractory metastatic renal cell carcinoma
    • Atlanta, GA;, p. 222s, Abstract, 4522
    • Rini BI, George DJ, Michaelson MD, et al. Efficacy and safety of sunitinib Malate (SU11248, Sutent) in bevacizumab-refractory metastatic renal cell carcinoma. In: ASCO Annual meeting; 2006; Atlanta, GA; 2006. p. 222s, Abstract # 4522.
    • (2006) ASCO Annual meeting , pp. 2006
    • Rini, B.I.1    George, D.J.2    Michaelson, M.D.3
  • 22
    • 33845297206 scopus 로고    scopus 로고
    • Efficacy and safety of sunitinib in previously treated advanced non-small cell lung cancer (NSCLC): Preliminary results of a multicenter phase II trial
    • 364s, Abstract
    • Socinski MA, Novello S, Sanchez JM, et al. Efficacy and safety of sunitinib in previously treated advanced non-small cell lung cancer (NSCLC): Preliminary results of a multicenter phase II trial. ASCO Annual Meeting Proceedings 2006;24: 364s, Abstract # 7001.
    • (2006) ASCO Annual Meeting Proceedings , vol.24 , Issue.7001
    • Socinski, M.A.1    Novello, S.2    Sanchez, J.M.3
  • 23
    • 58149093401 scopus 로고    scopus 로고
    • Continuous daily administration of sunitinib in patients with cytokine-refractory mestatic renal cell carcinoma: Updated results
    • June 20, Chicago, IL;, p. 244s
    • Srinivas S, Gillessen S, Hamenberg U, De Mulder PH, Fountzilas G, Vogelzang N, et al. Continuous daily administration of sunitinib in patients with cytokine-refractory mestatic renal cell carcinoma: Updated results. In: 43rd ASCO Annual Meeting; 2007 June 20, 2007; Chicago, IL; 2007. p. 244s.
    • (2007) 43rd ASCO Annual Meeting , pp. 2007
    • Srinivas, S.1    Gillessen, S.2    Hamenberg, U.3    De Mulder, P.H.4    Fountzilas, G.5    Vogelzang, N.6
  • 24
    • 30444442840 scopus 로고    scopus 로고
    • Controversies in hypertension
    • Kaplan NM, Opie LH. Controversies in hypertension. Lancet 2006;367:168-76.
    • (2006) Lancet , vol.367 , pp. 168-176
    • Kaplan, N.M.1    Opie, L.H.2
  • 25
    • 0028838569 scopus 로고
    • Blood pressure control, proteinuria, and the progression of renal disease. The modification of diet in renal disease study
    • Peterson JC, Adler S, Burkart JM, et al. Blood pressure control, proteinuria, and the progression of renal disease. The modification of diet in renal disease study. Ann Internal Med 1995;123:754-62.
    • (1995) Ann Internal Med , vol.123 , pp. 754-762
    • Peterson, J.C.1    Adler, S.2    Burkart, J.M.3
  • 26
    • 34848922067 scopus 로고    scopus 로고
    • Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome
    • Kapiteijn E, Brand A, Kroep J, Gelderblom H. Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome. Ann Oncol 2007;18:1745-7.
    • (2007) Ann Oncol , vol.18 , pp. 1745-1747
    • Kapiteijn, E.1    Brand, A.2    Kroep, J.3    Gelderblom, H.4
  • 27
    • 34548169627 scopus 로고    scopus 로고
    • Reversible posterior leukoencephalopathy syndrome induced by sunitinib
    • Martin G, Bellido L, Cruz JJ. Reversible posterior leukoencephalopathy syndrome induced by sunitinib. J Clin Oncol 2007;25:3559.
    • (2007) J Clin Oncol , vol.25 , pp. 3559
    • Martin, G.1    Bellido, L.2    Cruz, J.J.3
  • 28
    • 34248658559 scopus 로고    scopus 로고
    • Anti-vascular endotehlial growth factor (VEGF) therapy: A new cause of hypertension
    • accepted
    • Zhu X, Perazella MA. Anti-vascular endotehlial growth factor (VEGF) therapy: A new cause of hypertension. Hypertens Rev 2007;accepted.
    • (2007) Hypertens Rev
    • Zhu, X.1    Perazella, M.A.2
  • 29
    • 58149089285 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with sorafenib in cancer patients
    • in press
    • Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in cancer patients. Lancet Oncol 2008;(in press).
    • (2008) Lancet Oncol
    • Wu, S.1    Chen, J.J.2    Kudelka, A.3    Lu, J.4    Zhu, X.5
  • 30
    • 33846638744 scopus 로고    scopus 로고
    • Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
    • Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis. Am J Kidney Dis 2007;49:186-93.
    • (2007) Am J Kidney Dis , vol.49 , pp. 186-193
    • Zhu, X.1    Wu, S.2    Dahut, W.L.3    Parikh, C.R.4
  • 31
    • 33645451829 scopus 로고    scopus 로고
    • Angiogenesis inhibitors and hypertension: An emerging issue
    • Sica DA. Angiogenesis inhibitors and hypertension: An emerging issue. J Clin Oncol 2006;24:1329-31.
    • (2006) J Clin Oncol , vol.24 , pp. 1329-1331
    • Sica, D.A.1
  • 32
    • 58149087990 scopus 로고    scopus 로고
    • Mourad JJ, des Guetz G, Debbabi H, Levy BI. Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol 2007.
    • Mourad JJ, des Guetz G, Debbabi H, Levy BI. Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol 2007.
  • 33
    • 33645449812 scopus 로고    scopus 로고
    • Mechanisms of hypertension associated with BAY 43-9006
    • Veronese ML, Mosenkis A, Flaherty KT, et al. Mechanisms of hypertension associated with BAY 43-9006. J Clin Oncol 2006;24:1363-9.
    • (2006) J Clin Oncol , vol.24 , pp. 1363-1369
    • Veronese, M.L.1    Mosenkis, A.2    Flaherty, K.T.3
  • 34
    • 0022372166 scopus 로고
    • Limitations of creatinine as a filtration marker in glomerulopathic patients
    • Shemesh O, Golbetz H, Kriss JP, Myers BD. Limitations of creatinine as a filtration marker in glomerulopathic patients. Kidney Inter 1985;28:830-8.
    • (1985) Kidney Inter , vol.28 , pp. 830-838
    • Shemesh, O.1    Golbetz, H.2    Kriss, J.P.3    Myers, B.D.4
  • 35
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
    • Eremina V, Sood M, Haigh J, et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003;111:707-16.
    • (2003) J Clin Invest , vol.111 , pp. 707-716
    • Eremina, V.1    Sood, M.2    Haigh, J.3
  • 37
    • 25844519032 scopus 로고    scopus 로고
    • Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart
    • Siddiqui AJ, Mansson-Broberg A, Gustafsson T, et al. Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart. Am J Hypertens 2005;18:1347-52.
    • (2005) Am J Hypertens , vol.18 , pp. 1347-1352
    • Siddiqui, A.J.1    Mansson-Broberg, A.2    Gustafsson, T.3
  • 38
    • 33646739082 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor antagonist candesartan as an angiogenic inhibitor in a xenograft model of bladder cancer
    • Kosugi M, Miyajima A, Kikuchi E, Horiguchi Y, Murai M. Angiotensin II type 1 receptor antagonist candesartan as an angiogenic inhibitor in a xenograft model of bladder cancer. Clin Cancer Res 2006;12:2888-93.
    • (2006) Clin Cancer Res , vol.12 , pp. 2888-2893
    • Kosugi, M.1    Miyajima, A.2    Kikuchi, E.3    Horiguchi, Y.4    Murai, M.5
  • 39
    • 23244467359 scopus 로고    scopus 로고
    • Nifedipine-induced vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial tube formation via the kinase insert domain-containing receptor/fetal liver kinase-1/NO pathway
    • Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipine-induced vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial tube formation via the kinase insert domain-containing receptor/fetal liver kinase-1/NO pathway. Hypertens Res 2005;28:147-53.
    • (2005) Hypertens Res , vol.28 , pp. 147-153
    • Miura, S.1    Fujino, M.2    Matsuo, Y.3    Tanigawa, H.4    Saku, K.5
  • 40
    • 0037242152 scopus 로고    scopus 로고
    • Structural and functional changes of the microcirculation in hypertension: Influence of pharmacological therapy
    • Agabiti-Rosei E. Structural and functional changes of the microcirculation in hypertension: influence of pharmacological therapy. Drugs 2003;63:19-29.
    • (2003) Drugs , vol.63 , pp. 19-29
    • Agabiti-Rosei, E.1
  • 41
    • 58149100274 scopus 로고    scopus 로고
    • Mares JE, Worah S, Mathew SV, et al. Increased rates of hypertension (HTN) among patients with advanced carcinoid treated with bevacizumab. The 41st Annual Meeting of the American Society of Clinical Oncology (ASCO) 2005: Abstract No: 4087
    • Mares JE, Worah S, Mathew SV, et al. Increased rates of hypertension (HTN) among patients with advanced carcinoid treated with bevacizumab. The 41st Annual Meeting of the American Society of Clinical Oncology (ASCO) 2005: Abstract No: 4087


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.