-
1
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med. 2008;358:2039-2049.
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
2
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM, Hwu P, Schwartzentruber DJ, Topalian SL, Steinberg SM, Chen HX, Rosenberg SA. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349:427-434.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
3
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med. 2007;356:115-124.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
4
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, Negrier S, Chevreau C, Solska E, Desai AA, Rolland F, Demkow T, Hutson TE, Gore M, Freeman S, Schwartz B, Shan M, Simantov R, Bukowski RM. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007;356:125-134.
-
(2007)
N Engl J Med
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
5
-
-
38549085315
-
Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis
-
Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. Lancet Oncol. 2008;9:117-123.
-
(2008)
Lancet Oncol
, vol.9
, pp. 117-123
-
-
Wu, S.1
Chen, J.J.2
Kudelka, A.3
Lu, J.4
Zhu, X.5
-
6
-
-
58149098429
-
Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis
-
Zhu X, Stergiopoulos K, Wu S. Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. Acta Oncol. 2009;48:9-17.
-
(2009)
Acta Oncol
, vol.48
, pp. 9-17
-
-
Zhu, X.1
Stergiopoulos, K.2
Wu, S.3
-
7
-
-
77955523015
-
Incidence and risk of significantly raised blood pressure in cancer patients treated with bevacizumab: An updated meta-analysis.
-
An MM, Zou Z, Shen H, Liu P, Chen ML, Cao YB, Jiang YY. Incidence and risk of significantly raised blood pressure in cancer patients treated with bevacizumab: an updated meta-analysis. Eur J Clin Pharmacol. 2010;66:813-821.
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 813-821
-
-
An, M.M.1
Zou, Z.2
Shen, H.3
Liu, P.4
Chen, M.L.5
Cao, Y.B.6
Jiang, Y.Y.7
-
8
-
-
77749282844
-
Rapid development of hypertension and proteinuria with cediranib, an oral vascular endothelial growth factor receptor inhibitor
-
Robinson ES, Matulonis UA, Ivy P, Berlin ST, Tyburski K, Penson RT, Humphreys BD. Rapid development of hypertension and proteinuria with cediranib, an oral vascular endothelial growth factor receptor inhibitor. Clin J Am Soc Nephrol. 2010;5:477-483.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 477-483
-
-
Robinson, E.S.1
Matulonis, U.A.2
Ivy, P.3
Berlin, S.T.4
Tyburski, K.5
Penson, R.T.6
Humphreys, B.D.7
-
9
-
-
77952038495
-
Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors
-
Maitland ML, Bakris GL, Black HR, Chen HX, Durand JB, Elliott WJ, Ivy SP, Leier CV, Lindenfeld J, Liu G, Remick SC, Steingart R, Tang WH. Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors. J Natl Cancer Inst. 2010;102:596-604.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 596-604
-
-
Maitland, M.L.1
Bakris, G.L.2
Black, H.R.3
Chen, H.X.4
Durand, J.B.5
Elliott, W.J.6
Ivy, S.P.7
Leier, C.V.8
Lindenfeld, J.9
Liu, G.10
Remick, S.C.11
Steingart, R.12
Tang, W.H.13
-
11
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov. 2004;3:391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
13
-
-
0031943236
-
VEGF upregulates ecnos message, protein, and no production in human endothelial cells
-
Hood JD, Meininger CJ, Ziche M, Granger HJ. VEGF upregulates ecnos message, protein, and no production in human endothelial cells. Am J Physiol. 1998;274:H1054-H1058.
-
(1998)
Am J Physiol
, vol.274
-
-
Hood, J.D.1
Meininger, C.J.2
Ziche, M.3
Granger, H.J.4
-
14
-
-
78650419842
-
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors
-
Robinson ES, Khankin EV, Choueiri TK, Dhawan MS, Rogers MJ, Karumanchi SA, Humphreys BD. Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors. Hypertension. 2010;56:1131-1136.
-
(2010)
Hypertension
, vol.56
, pp. 1131-1136
-
-
Robinson, E.S.1
Khankin, E.V.2
Choueiri, T.K.3
Dhawan, M.S.4
Rogers, M.J.5
Karumanchi, S.A.6
Humphreys, B.D.7
-
15
-
-
79959723693
-
Contrary effects of the receptor tyrosine kinase inhibitor vandetanib on constitutive and flow-stimulated nitric oxide elaboration in humans
-
Mayer EL, Dallabrida SM, Rupnick MA, Redline WM, Hannagan K, Ismail NS, Burstein HJ, Beckman JA. Contrary effects of the receptor tyrosine kinase inhibitor vandetanib on constitutive and flow-stimulated nitric oxide elaboration in humans. Hypertension. 2011;58:85-92.
-
(2011)
Hypertension
, vol.58
, pp. 85-92
-
-
Mayer, E.L.1
Dallabrida, S.M.2
Rupnick, M.A.3
Redline, W.M.4
Hannagan, K.5
Ismail, N.S.6
Burstein, H.J.7
Beckman, J.A.8
-
16
-
-
83655165286
-
Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress
-
Kappers MH, de Beer VJ, Zhou Z, Danser AH, Sleijfer S, Duncker DJ, van den Meiracker AH, Merkus D. Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress. Hypertension. 2012;59:151-157.
-
(2012)
Hypertension
, vol.59
, pp. 151-157
-
-
Kappers, M.H.1
De Beer, V.J.2
Zhou, Z.3
Danser, A.H.4
Sleijfer, S.5
Duncker, D.J.6
Van Den Meiracker, A.H.7
Merkus, D.8
-
17
-
-
70349249625
-
Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression
-
Facemire CS, Nixon AB, Griffiths R, Hurwitz H, Coffman TM. Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. Hypertension. 2009;54:652-658.
-
(2009)
Hypertension
, vol.54
, pp. 652-658
-
-
Facemire, C.S.1
Nixon, A.B.2
Griffiths, R.3
Hurwitz, H.4
Coffman, T.M.5
-
18
-
-
77957231200
-
Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels
-
Kappers MH, van Esch JH, Sluiter W, Sleijfer S, Danser AH, van den Meiracker AH. Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels. Hypertension. 2010;56:675-681.
-
(2010)
Hypertension
, vol.56
, pp. 675-681
-
-
Kappers, M.H.1
Van Esch, J.H.2
Sluiter, W.3
Sleijfer, S.4
Danser, A.H.5
Van Den Meiracker, A.H.6
-
19
-
-
84866410804
-
Regorafenib induces rapid and reversible changes in plasma nitric oxide and endothelin-1
-
July 12 DOI: 10.1038/ajh.2012.97 Accessed July 18, 2012
-
de Jesus-Gonzalez N, Robinson ES, Penchev RR, von Mehren M, Heinrich MC, Tap W, Demetri GD, George S, Humphreys BD. Regorafenib induces rapid and reversible changes in plasma nitric oxide and endothelin-1. Am J Hypertens. July 12, 2012. DOI: 10.1038/ajh.2012.97. http://www.nature.com/ajh/journal/vaop/ ncurrent/full/ajh201297a.html. Accessed July 18, 2012.
-
(2012)
Am J Hypertens
-
-
De Jesus-Gonzalez, N.1
Robinson, E.S.2
Penchev, R.R.3
Von Mehren, M.4
Heinrich, M.C.5
Tap, W.6
Demetri, G.D.7
George, S.8
Humphreys, B.D.9
-
20
-
-
80051470809
-
The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system
-
Kappers MH, Smedts FM, Horn T, van Esch JH, Sleijfer S, Leijten F, Wesseling S, Strevens H, Jan Danser AH, van den Meiracker AH. The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system. Hypertension. 2011;58:295-302.
-
(2011)
Hypertension
, vol.58
, pp. 295-302
-
-
Kappers, M.H.1
Smedts, F.M.2
Horn, T.3
Van Esch, J.H.4
Sleijfer, S.5
Leijten, F.6
Wesseling, S.7
Strevens, H.8
Jan Danser, A.H.9
Van Den Meiracker, A.H.10
-
21
-
-
34548415037
-
The importance of endothelin-1 for vascular dysfunction in cardiovascular disease
-
Bohm F, Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res. 2007;76:8-18.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 8-18
-
-
Bohm, F.1
Pernow, J.2
-
22
-
-
32944466693
-
Cellular changes in normal blood capillaries undergoing regression after inhibition of vegf signaling
-
Baffert F, Le T, Sennino B, Thurston G, Kuo CJ, Hu-Lowe D, McDonald DM. Cellular changes in normal blood capillaries undergoing regression after inhibition of vegf signaling. Am J Physiol Heart Circ Physiol. 2006;290:H547-H559.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Baffert, F.1
Le Sennino T, B.2
Thurston, G.3
Kuo, C.J.4
Hu-Lowe, D.5
McDonald, D.M.6
-
23
-
-
43049085201
-
Blood pressure rise following angiogenesis inhibition by bevacizumab: A crucial role for microcirculation
-
Mourad JJ, des Guetz G, Debbabi H, Levy BI. Blood pressure rise following angiogenesis inhibition by bevacizumab: a crucial role for microcirculation. Ann Oncol. 2008;19:927-934.
-
(2008)
Ann Oncol
, vol.19
, pp. 927-934
-
-
Mourad, J.J.1
Des Guetz, G.2
Debbabi, H.3
Levy, B.I.4
-
24
-
-
50349101200
-
Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor
-
Steeghs N, Gelderblom H, Roodt JO, Christensen O, Rajagopalan P, Hovens M, Putter H, Rabelink TJ, de Koning E. Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor. Clin Cancer Res. 2008;14:3470-3476.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3470-3476
-
-
Steeghs, N.1
Gelderblom, H.2
Roodt, J.O.3
Christensen, O.4
Rajagopalan, P.5
Hovens, M.6
Putter, H.7
Rabelink, T.J.8
De Koning, E.9
-
25
-
-
0024557970
-
Microvascular rarefaction and tissue vascular resistance in hypertension
-
Greene AS, Tonellato PJ, Lui J, Lombard JH, Cowley AW Jr. Microvascular rarefaction and tissue vascular resistance in hypertension. Am J Physiol. 1989;256:H126-H131.
-
(1989)
Am J Physiol
, vol.256
-
-
Greene, A.S.1
Tonellato, P.J.2
Lui, J.3
Lombard, J.H.4
Cowley Jr., A.W.5
-
26
-
-
0031583917
-
Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase a2 in endothelial cells via p42/p44 mitogen-activated protein kinase
-
Wheeler-Jones C, Abu-Ghazaleh R, Cospedal R, Houliston RA, Martin J, Zachary I. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase a2 in endothelial cells via p42/p44 mitogen-activated protein kinase. FEBS Lett. 1997;420: 28-32.
-
(1997)
FEBS Lett
, vol.420
, pp. 28-32
-
-
Wheeler-Jones, C.1
Abu-Ghazaleh, R.2
Cospedal, R.3
Houliston, R.A.4
Martin, J.5
Zachary, I.6
-
27
-
-
0035514402
-
Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a rac1-regulated nadph oxidasedependent mechanism
-
Abid MR, Tsai JC, Spokes KC, Deshpande SS, Irani K, Aird WC. Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a rac1-regulated nadph oxidasedependent mechanism. FASEB J. 2001;15:2548-2550.
-
(2001)
FASEB J
, vol.15
, pp. 2548-2550
-
-
Abid, M.R.1
Tsai, J.C.2
Spokes, K.C.3
Deshpande, S.S.4
Irani, K.5
Aird, W.C.6
-
28
-
-
33645449812
-
Mechanisms of hypertension associated with bay 43-9006
-
Veronese ML, Mosenkis A, Flaherty KT, Gallagher M, Stevenson JP, Townsend RR, O'Dwyer PJ. Mechanisms of hypertension associated with bay 43-9006. J Clin Oncol. 2006;24:1363-1369.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1363-1369
-
-
Veronese, M.L.1
Mosenkis, A.2
Flaherty, K.T.3
Gallagher, M.4
Stevenson, J.P.5
Townsend, R.R.6
O'Dwyer, P.J.7
-
29
-
-
66749106368
-
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-cdependent buffering mechanism
-
Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Muller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-cdependent buffering mechanism. Nat Med. 2009;15:545-552.
-
(2009)
Nat Med
, vol.15
, pp. 545-552
-
-
MacHnik, A.1
Neuhofer, W.2
Jantsch, J.3
Dahlmann, A.4
Tammela, T.5
MacHura, K.6
Park, J.K.7
Beck, F.X.8
Muller, D.N.9
Derer, W.10
Goss, J.11
Ziomber, A.12
Dietsch, P.13
Wagner, H.14
Van Rooijen, N.15
Kurtz, A.16
Hilgers, K.F.17
Alitalo, K.18
Eckardt, K.U.19
Luft, F.C.20
Kerjaschki, D.21
Titze, J.22
more..
-
30
-
-
39649122843
-
A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib
-
Patel TV, Morgan JA, Demetri GD, George S, Maki RG, Quigley M, Humphreys BD. A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib. J Natl Cancer Inst. 2008;100: 282-284.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 282-284
-
-
Patel, T.V.1
Morgan, J.A.2
Demetri, G.D.3
George, S.4
Maki, R.G.5
Quigley, M.6
Humphreys, B.D.7
-
31
-
-
10744228140
-
Ctcae v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment
-
Trotti A, Colevas AD, Setser A, Rusch V, Jaques D, Budach V, Langer C, Murphy B, Cumberlin R, Coleman CN, Rubin P. Ctcae v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol. 2003;13:176-181.
-
(2003)
Semin Radiat Oncol
, vol.13
, pp. 176-181
-
-
Trotti, A.1
Colevas, A.D.2
Setser, A.3
Rusch, V.4
Jaques, D.5
Budach, V.6
Langer, C.7
Murphy, B.8
Cumberlin, R.9
Coleman, C.N.10
Rubin, P.11
-
32
-
-
0038460302
-
The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report
-
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289:2560-2572.
-
(2003)
JAMA
, vol.289
, pp. 2560-2572
-
-
Chobanian, A.V.1
Bakris, G.L.2
Black, H.R.3
Cushman, W.C.4
Green, L.A.5
Izzo Jr., J.L.6
Jones, D.W.7
Materson, B.J.8
Oparil, S.9
Wright Jr., J.T.10
Roccella, E.J.11
-
33
-
-
84859393599
-
Suicide and cardiovascular death after a cancer diagnosis
-
Fang F, Fall K, Mittleman MA, Sparen P, Ye W, Adami HO, Valdimarsdottir U. Suicide and cardiovascular death after a cancer diagnosis. N Engl J Med. 2012;366:1310-1318.
-
(2012)
N Engl J Med
, vol.366
, pp. 1310-1318
-
-
Fang, F.1
Fall, K.2
Mittleman, M.A.3
Sparen, P.4
Ye, W.5
Adami, H.O.6
Valdimarsdottir, U.7
-
34
-
-
33644586050
-
Reversible posterior leukoencephalopathy syndrome and bevacizumab
-
discussion 980-982
-
Glusker P, Recht L, Lane B. Reversible posterior leukoencephalopathy syndrome and bevacizumab. N Engl J Med. 2006;354:980-982; discussion 980-982.
-
(2006)
N Engl J Med
, vol.354
, pp. 980-982
-
-
Glusker, P.1
Recht, L.2
Lane, B.3
-
35
-
-
13444255966
-
Recommendations for blood pressure measurement in humans and experimental animals: Part 1-blood pressure measurement in humans: A statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research
-
Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans and experimental animals: part 1-blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005;111: 697-716.
-
(2005)
Circulation
, vol.111
, pp. 697-716
-
-
Pickering, T.G.1
Hall, J.E.2
Appel, L.J.3
Falkner, B.E.4
Graves, J.5
Hill, M.N.6
Jones, D.W.7
Kurtz, T.8
Sheps, S.G.9
Roccella, E.J.10
-
36
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
37
-
-
70349696526
-
Ambulatory monitoring detects sorafenib-induced blood pressure elevations on the first day of treatment
-
Maitland ML, Kasza KE, Karrison T, Moshier K, Sit L, Black HR, Undevia SD, Stadler WM, Elliott WJ, Ratain MJ. Ambulatory monitoring detects sorafenib-induced blood pressure elevations on the first day of treatment. Clin Cancer Res. 2009;15:6250-6257.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6250-6257
-
-
Maitland, M.L.1
Kasza, K.E.2
Karrison, T.3
Moshier, K.4
Sit, L.5
Black, H.R.6
Undevia, S.D.7
Stadler, W.M.8
Elliott, W.J.9
Ratain, M.J.10
-
38
-
-
38049092600
-
Home blood-pressure monitoring in patients receiving sunitinib
-
Azizi M, Chedid A, Oudard S. Home blood-pressure monitoring in patients receiving sunitinib. N Engl J Med. 2008;358:95-97.
-
(2008)
N Engl J Med
, vol.358
, pp. 95-97
-
-
Azizi, M.1
Chedid, A.2
Oudard, S.3
-
39
-
-
80054003549
-
Effects of novel angiogenesis inhibitors for the treatment of cancer on the cardiovascular system: Focus on hypertension
-
Nazer B, Humphreys BD, Moslehi J. Effects of novel angiogenesis inhibitors for the treatment of cancer on the cardiovascular system: focus on hypertension. Circulation. 2011;124:1687-1691.
-
(2011)
Circulation
, vol.124
, pp. 1687-1691
-
-
Nazer, B.1
Humphreys, B.D.2
Moslehi, J.3
-
41
-
-
35348984015
-
Hypertension secondary to anti-angiogenic therapy: Experience with bevacizumab
-
Pande A, Lombardo J, Spangenthal E, Javle M. Hypertension secondary to anti-angiogenic therapy: experience with bevacizumab. Anticancer Res. 2007;27:3465-3470.
-
(2007)
Anticancer Res
, vol.27
, pp. 3465-3470
-
-
Pande, A.1
Lombardo, J.2
Spangenthal, E.3
Javle, M.4
-
42
-
-
84861716353
-
Treatment of bevacizumab-induced hypertension by amlodipine
-
Mir OCR, Ropert S, Cabanes L, Blanchet B, Camps S, Billemont B, Knebelmann B, Goldwasser F. Treatment of bevacizumab-induced hypertension by amlodipine. Invest New Drugs. 2012;30:702-707.
-
(2012)
Invest New Drugs
, vol.30
, pp. 702-707
-
-
Ocr, M.1
Ropert, S.2
Cabanes, L.3
Blanchet, B.4
Camps, S.5
Billemont, B.6
Knebelmann, B.7
Goldwasser, F.8
-
43
-
-
65549122619
-
Management of hypertension in angiogenesis inhibitor-treated patients
-
Izzedine H, Ederhy S, Goldwasser F, Soria JC, Milano G, Cohen A, Khayat D, Spano JP. Management of hypertension in angiogenesis inhibitor-treated patients. Ann Oncol. 2009;20:807-815.
-
(2009)
Ann Oncol
, vol.20
, pp. 807-815
-
-
Izzedine, H.1
Ederhy, S.2
Goldwasser, F.3
Soria, J.C.4
Milano, G.5
Cohen, A.6
Khayat, D.7
Spano, J.P.8
-
44
-
-
33846638744
-
Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
-
Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am J Kidney Dis. 2007;49:186-193.
-
(2007)
Am J Kidney Dis
, vol.49
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
45
-
-
34447635695
-
Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension
-
Izzedine H, Rixe O, Billemont B, Baumelou A, Deray G. Angiogenesis inhibitor therapies: focus on kidney toxicity and hypertension. Am J Kidney Dis. 2007;50:203-218.
-
(2007)
Am J Kidney Dis
, vol.50
, pp. 203-218
-
-
Izzedine, H.1
Rixe, O.2
Billemont, B.3
Baumelou, A.4
Deray, G.5
-
46
-
-
78649932949
-
Biology of anti-angiogenic therapy-induced thrombotic microangiopathy
-
Eremina V, Quaggin SE. Biology of anti-angiogenic therapy-induced thrombotic microangiopathy. Semin Nephrol. 2010;30:582-590.
-
(2010)
Semin Nephrol
, vol.30
, pp. 582-590
-
-
Eremina, V.1
Quaggin, S.E.2
-
47
-
-
49649091098
-
Inhibition of vascular endothelial growth factor - A signaling induces hypertension: Examining the effect of cediranib (recentin; Azd2171) treatment on blood pressure in rat and the use of concomitant antihypertensive therapy
-
Curwen JO, Musgrove HL, Kendrew J, Richmond GH, Ogilvie DJ, Wedge SR. Inhibition of vascular endothelial growth factor-a signaling induces hypertension: examining the effect of cediranib (recentin; azd2171) treatment on blood pressure in rat and the use of concomitant antihypertensive therapy. Clin Cancer Res. 2008;14:3124-3131.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3124-3131
-
-
Curwen, J.O.1
Musgrove, H.L.2
Kendrew, J.3
Richmond, G.H.4
Ogilvie, D.J.5
Wedge, S.R.6
-
48
-
-
74949128620
-
Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: Results from a phase II randomized, factorial, double-blind study of cediranib in patients with advanced solid tumors
-
Langenberg MH, van Herpen CM, De Bono J, Schellens JH, Unger C, Hoekman K, Blum HE, Fiedler W, Drevs J, Le Maulf F, Fielding A, Robertson J, Voest EE. Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: results from a phase II randomized, factorial, double-blind study of cediranib in patients with advanced solid tumors. J Clin Oncol. 2009;27: 6152-6159.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6152-6159
-
-
Langenberg, M.H.1
Van Herpen, C.M.2
De Bono, J.3
Schellens, J.H.4
Unger, C.5
Hoekman, K.6
Blum, H.E.7
Fiedler, W.8
Drevs, J.9
Le Maulf, F.10
Fielding, A.11
Robertson, J.12
Voest, E.E.13
-
49
-
-
34447345394
-
Treatment of arterial hypertension (AHT) associated with angiogenesis inhibitors
-
Dirix LY, Maes H, Sweldens C. Treatment of arterial hypertension (AHT) associated with angiogenesis inhibitors. Ann Oncol. 2007;18:1121-1122.
-
(2007)
Ann Oncol
, vol.18
, pp. 1121-1122
-
-
Dirix, L.Y.1
Maes, H.2
Sweldens, C.3
-
50
-
-
0037035443
-
Nitric oxide and angiogenesis
-
Cooke JP, Losordo DW. Nitric oxide and angiogenesis. Circulation. 2002;105:2133-2135.
-
(2002)
Circulation
, vol.105
, pp. 2133-2135
-
-
Cooke, J.P.1
Losordo, D.W.2
-
51
-
-
0031008458
-
Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factorinduced angiogenesis
-
Ziche M, Morbidelli L, Choudhuri R, Zhang HT, Donnini S, Granger HJ, Bicknell R. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factorinduced angiogenesis. J Clin Invest. 1997;99:2625-2634.
-
(1997)
J Clin Invest
, vol.99
, pp. 2625-2634
-
-
Ziche, M.1
Morbidelli, L.2
Choudhuri, R.3
Zhang, H.T.4
Donnini, S.5
Granger, H.J.6
Bicknell, R.7
-
52
-
-
0035956947
-
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
-
Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, Huang PL, Jain RK. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci USA. 2001;98:2604-2609.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2604-2609
-
-
Fukumura, D.1
Gohongi, T.2
Kadambi, A.3
Izumi, Y.4
Ang, J.5
Yun, C.O.6
Buerk, D.G.7
Huang, P.L.8
Jain, R.K.9
-
53
-
-
78149237594
-
Dorado: Opportunity postponed: Lessons from studies of endothelin receptor antagonists in treatment-resistant hypertension
-
Webb DJ. Dorado: Opportunity postponed: lessons from studies of endothelin receptor antagonists in treatment-resistant hypertension. Hypertension. 2010;56:806-807.
-
(2010)
Hypertension
, vol.56
, pp. 806-807
-
-
Webb, D.J.1
-
54
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG. New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000;92:205-216.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
Verweij, J.7
Van Glabbeke, M.8
Van Oosterom, A.T.9
Christian, M.C.10
Gwyther, S.G.11
-
55
-
-
34447343347
-
Hypertension as a predictive factor of sunitinib activity
-
Rixe O, Billemont B, Izzedine H. Hypertension as a predictive factor of sunitinib activity. Ann Oncol. 2007;18:1117.
-
(2007)
Ann Oncol
, vol.18
, pp. 1117
-
-
Rixe, O.1
Billemont, B.2
Izzedine, H.3
-
56
-
-
60549095633
-
Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma
-
Bono P, Elfving H, Utriainen T, Osterlund P, Saarto T, Alanko T, Joensuu H. Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma. Ann Oncol. 2009;20:393-394.
-
(2009)
Ann Oncol
, vol.20
, pp. 393-394
-
-
Bono, P.1
Elfving, H.2
Utriainen, T.3
Osterlund, P.4
Saarto, T.5
Alanko, T.6
Joensuu, H.7
-
57
-
-
79957909038
-
Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors
-
Rini BI, Schiller JH, Fruehauf JP, Cohen EE, Tarazi JC, Rosbrook B, Bair AH, Ricart AD, Olszanski AJ, Letrent KJ, Kim S, Rixe O. Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors. Clin Cancer Res. 2011;17:3841-3849.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3841-3849
-
-
Rini, B.I.1
Schiller, J.H.2
Fruehauf, J.P.3
Cohen, E.E.4
Tarazi, J.C.5
Rosbrook, B.6
Bair, A.H.7
Ricart, A.D.8
Olszanski, A.J.9
Letrent, K.J.10
Kim, S.11
Rixe, O.12
-
58
-
-
77958470973
-
Treatment-emergent hypertension and outcomes in patients with advanced non-small-cell lung cancer receiving chemotherapy with or without the vascular endothelial growth factor receptor inhibitor cediranib: NCIC Clinical Trials Group Study br24
-
Goodwin R, Ding K, Seymour L, LeMaitre A, Arnold A, Shepherd FA, Dediu M, Ciuleanu T, Fenton D, Zukin M, Walde D, Laberge F, Vincent M, Ellis PM, Laurie SA. Treatment-emergent hypertension and outcomes in patients with advanced non-small-cell lung cancer receiving chemotherapy with or without the vascular endothelial growth factor receptor inhibitor cediranib: NCIC Clinical Trials Group Study br24. Ann Oncol. 2010;21:2220-2226.
-
(2010)
Ann Oncol
, vol.21
, pp. 2220-2226
-
-
Goodwin, R.1
Ding, K.2
Seymour, L.3
Lemaitre, A.4
Arnold, A.5
Shepherd, F.A.6
Dediu, M.7
Ciuleanu, T.8
Fenton, D.9
Zukin, M.10
Walde, D.11
Laberge, F.12
Vincent, M.13
Ellis, P.M.14
Laurie, S.A.15
-
59
-
-
79955767772
-
Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib
-
Rini BI, Cohen DP, Lu DR, Chen I, Hariharan S, Gore ME, Figlin RA, Baum MS, Motzer RJ. Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst. 2011;103:763-773.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 763-773
-
-
Rini, B.I.1
Cohen, D.P.2
Lu, D.R.3
Chen, I.4
Hariharan, S.5
Gore, M.E.6
Figlin, R.A.7
Baum, M.S.8
Motzer, R.J.9
-
60
-
-
53749093040
-
Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
-
Schneider BP, Wang M, Radovich M, Sledge GW, Badve S, Thor A, Flockhart DA, Hancock B, Davidson N, Gralow J, Dickler M, Perez EA, Cobleigh M, Shenkier T, Edgerton S, Miller KD. Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100. J Clin Oncol. 2008;26:4672-4678.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4672-4678
-
-
Schneider, B.P.1
Wang, M.2
Radovich, M.3
Sledge, G.W.4
Badve, S.5
Thor, A.6
Flockhart, D.A.7
Hancock, B.8
Davidson, N.9
Gralow, J.10
Dickler, M.11
Perez, E.A.12
Cobleigh, M.13
Shenkier, T.14
Edgerton, S.15
Miller, K.D.16
-
61
-
-
84863338437
-
Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib
-
Kim JJ, Vaziri SA, Rini BI, Elson P, Garcia JA, Wirka R, Dreicer R, Ganapathi MK, Ganapathi R. Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib. Cancer. 2012;118:1946-1954.
-
(2012)
Cancer
, vol.118
, pp. 1946-1954
-
-
Kim, J.J.1
Vaziri, S.A.2
Rini, B.I.3
Elson, P.4
Garcia, J.A.5
Wirka, R.6
Dreicer, R.7
Ganapathi, M.K.8
Ganapathi, R.9
-
62
-
-
34548141828
-
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
-
Scappaticci FA, Skillings JR, Holden SN, Gerber HP, Miller K, Kabbinavar F, Bergsland E, Ngai J, Holmgren E, Wang J, Hurwitz H. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst. 2007;99:1232-1239.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1232-1239
-
-
Scappaticci, F.A.1
Skillings, J.R.2
Holden, S.N.3
Gerber, H.P.4
Miller, K.5
Kabbinavar, F.6
Bergsland, E.7
Ngai, J.8
Holmgren, E.9
Wang, J.10
Hurwitz, H.11
-
63
-
-
77951269420
-
Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis of randomized controlled trials
-
Ranpura V, Hapani S, Chuang J, Wu S. Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials. Acta Oncol. 2010;49:287-297.
-
(2010)
Acta Oncol
, vol.49
, pp. 287-297
-
-
Ranpura, V.1
Hapani, S.2
Chuang, J.3
Wu, S.4
-
64
-
-
79957790694
-
Bevacizumab increases the risk of arterial ischemia: A large study in cancer patients with a focus on different subgroup outcomes
-
Schutz FA, Je Y, Azzi GR, Nguyen PL, Choueiri TK. Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes. Ann Oncol. 2011;22:1404-1412.
-
(2011)
Ann Oncol
, vol.22
, pp. 1404-1412
-
-
Schutz, F.A.1
Je, Y.2
Azzi, G.R.3
Nguyen, P.L.4
Choueiri, T.K.5
-
65
-
-
77952310126
-
Risk of arterial thromboembolic events with sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
-
Choueiri TK, Schutz FA, Je Y, Rosenberg JE, Bellmunt J. Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J Clin Oncol. 2010;28:2280-2285.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2280-2285
-
-
Choueiri, T.K.1
Schutz, F.A.2
Je, Y.3
Rosenberg, J.E.4
Bellmunt, J.5
-
66
-
-
56649123212
-
Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis
-
Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA. 2008;300:2277-2285.
-
(2008)
JAMA
, vol.300
, pp. 2277-2285
-
-
Nalluri, S.R.1
Chu, D.2
Keresztes, R.3
Zhu, X.4
Wu, S.5
-
67
-
-
79955587689
-
Venous thromboembolic events with chemotherapy plus bevacizumab: A pooled analysis of patients in randomized phase II and III studies
-
Hurwitz HI, Saltz LB, Van Cutsem E, Cassidy J, Wiedemann J, Sirzen F, Lyman GH, Rohr UP. Venous thromboembolic events with chemotherapy plus bevacizumab: a pooled analysis of patients in randomized phase II and III studies. J Clin Oncol. 2011;29:1757-1764.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1757-1764
-
-
Hurwitz, H.I.1
Saltz, L.B.2
Van Cutsem, E.3
Cassidy, J.4
Wiedemann, J.5
Sirzen, F.6
Lyman, G.H.7
Rohr, U.P.8
|