Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway

Acta Pharmacologica Sinica

Volumn 35, Issue 6, 2014, Pages 707-715

  Wei, Hai Jun ^a   Xu, Jin Hua ^a   Li, Man Hong ^a   Tang, Ji Ping ^a   Zou, Wei ^a   Zhang, Ping ^a   Wang, Li ^a   Wang, Chun Yan ^a   Tang, Xiao Qing ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Alzheimers disease; apoptosis; BDNF; ER stress; hippocampus; homocysteine; Hydrogen sulfide; neurotoxicity; tyrosine protein kinase B

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE 12; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HOMOCYSTEINE; HYDROGEN SULFIDE; K 252A; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN SLICE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME METABOLISM; HIPPOCAMPAL CA1 REGION; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PC12 CELL LINE; RAT; UPREGULATION; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; HIPPOCAMPUS; HYPERHOMOCYSTEINEMIA; METABOLISM; NERVE CELL; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; HOMOCYSTEINE; HYDROGEN SULFIDE; HYPERHOMOCYSTEINEMIA; MALE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84902244912     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.197     Document Type: Article

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