Reactive oxygen species induce MMP12-dependent degradation of collagen 5 and fibronectin to promote the motility of human umbilical cord-derived mesenchymal stem cells

British Journal of Pharmacology

Volumn 171, Issue 13, 2014, Pages 3283-3297

  Yun, Seung Pil ^a   Lee, Sei Jung ^a   Oh, Sang Yub ^a   Jung, Young Hyun ^a   Ryu, Jung Min ^a   Suh, Han Na ^a   Kim, Mi Ok ^a   Oh, Keon Bong ^b   Han, Ho Jae ^a  

^a Seoul National University   (South Korea)

^b National Institute of Animal Science   (South Korea)

Author keywords

extracellular matrix proteins; hydrogen peroxide; MMP; motility; skin wound healing; umbilical cord blood derived mesenchymal stem cells

Indexed keywords

BETA CATENIN; COLLAGEN TYPE 5; FIBRONECTIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C ALPHA; REACTIVE OXYGEN METABOLITE; SCLEROPROTEIN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL MOTILITY; COLLAGEN DEGRADATION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN INJURY; UMBILICAL CORD; WOUND HEALING; ANIMAL; CELL MOTION; CYTOLOGY; DISEASE MODEL; INJURY; INSTITUTE FOR CANCER RESEARCH MOUSE; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; SKIN;

ANIMALS; BETA CATENIN; CELL MOVEMENT; COLLAGEN TYPE V; DISEASE MODELS, ANIMAL; FEMALE; FIBRONECTINS; HUMANS; HYDROGEN PEROXIDE; MATRIX METALLOPROTEINASE 12; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED ICR; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; UMBILICAL CORD; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84902205512     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12681     Document Type: Article

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