Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages

Toxicology and Applied Pharmacology

Volumn 273, Issue 1, 2013, Pages 77-89

  Kim, Mi Jin ^a   Nepal, Saroj ^a   Lee, Eung Seok ^a   Jeong, Tae Cheon ^a   Kim, Sang Hyun ^b   Park, Pil Hoon ^a  

^a Yeungnam University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

Author keywords

Ethanol; MMP 12; NADPH oxidase; NF B; P38 MAPK; ROS

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ACETYLCYSTEINE; ALCOHOL; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE ELASTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P22; PROTEIN P40; PROTEIN P47; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; ATTENUATION; ENZYME ACTIVITY; FEMALE; GENE SILENCING; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSIENT TRANSFECTION;

ETHANOL; MMP-12; NADPH OXIDASE; NF-ΚB; P38 MAPK; ROS;

ACETYLCYSTEINE; ANIMALS; CELL LINE, TUMOR; ETHANOL; FEMALE; I-KAPPA B PROTEINS; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NADPH OXIDASE; NF-KAPPA B; NITRILES; ONIUM COMPOUNDS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SULFONES;

EID: 84884719975     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.08.005     Document Type: Article

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