4-1BB Signaling Activates the T Cell Factor 1 Effector/β-Catenin Pathway with Delayed Kinetics via ERK Signaling and Delayed PI3K/AKT Activation to Promote the Proliferation of CD8+ T Cells

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Lee, Do Y ^a   Choi, Beom K ^a   Lee, Don G ^a   Kim, Young H ^a   Kim, Chang H ^a   Lee, Seung J ^a   Kwon, Byoung S ^a,b  

^a National Cancer Center   (South Korea)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD137 ANTIGEN; GAMMA INTERFERON; GLYCOGEN SYNTHASE KINASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; QUERCETIN; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR FKHR; WNT10B PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; WNT10B GENE; WNT3A GENE; WNT5A GENE;

ANIMALS; ANTIGENS, CD137; BETA CATENIN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; I-KAPPA B PROTEINS; KINETICS; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; T CELL TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTORS;

EID: 84880071725     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069677     Document Type: Article

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