-
1
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS,. 2001. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 107: 241-246.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
2
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M,. 1997. Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336: 1066-1071.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
3
-
-
0142088867
-
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family
-
Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C, Kroemer G,. 2003. The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. Oncogene 22: 6220-6230.
-
(2003)
Oncogene
, vol.22
, pp. 6220-6230
-
-
Boya, P.1
Morales, M.C.2
Gonzalez-Polo, R.A.3
Andreau, K.4
Gourdier, I.5
Perfettini, J.L.6
Larochette, N.7
Deniaud, A.8
Baran-Marszak, F.9
Fagard, R.10
Feuillard, J.11
Asumendi, A.12
Raphael, M.13
Pau, B.14
Brenner, C.15
Kroemer, G.16
-
4
-
-
0032496143
-
Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
-
Cai J, Jones DP,. 1998. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem 273: 11401-11404.
-
(1998)
J Biol Chem
, vol.273
, pp. 11401-11404
-
-
Cai, J.1
Jones, D.P.2
-
5
-
-
2342522110
-
Shaping the nuclear action of NF-kappaB
-
Chen LF, Greene WC,. 2004. Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol 5: 392-401.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 392-401
-
-
Chen, L.F.1
Greene, W.C.2
-
6
-
-
77949912138
-
Nuclear-targeted inhibition of NF-kappaB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells
-
Chou YC, Sheu JR, Chung CL, Chen CY, Lin FL, Hsu MJ, Kuo YH, Hsiao G,. 2010. Nuclear-targeted inhibition of NF-kappaB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells. Chem Biol Interact 184: 403-412.
-
(2010)
Chem Biol Interact
, vol.184
, pp. 403-412
-
-
Chou, Y.C.1
Sheu, J.R.2
Chung, C.L.3
Chen, C.Y.4
Lin, F.L.5
Hsu, M.J.6
Kuo, Y.H.7
Hsiao, G.8
-
7
-
-
0025880967
-
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia
-
De Luca LM,. 1991. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia. FASEB J 5: 2924-2933.
-
(1991)
FASEB J
, vol.5
, pp. 2924-2933
-
-
De Luca, L.M.1
-
8
-
-
32944459251
-
Matrix metalloproteinases: Roles in cancer and metastasis
-
Fingleton B,. 2006. Matrix metalloproteinases: Roles in cancer and metastasis. Front Biosci 11: 479-491.
-
(2006)
Front Biosci
, vol.11
, pp. 479-491
-
-
Fingleton, B.1
-
9
-
-
0036234606
-
Classical and novel retinoids: Their targets in cancer therapy
-
Fontana JA, Rishi AK,. 2002. Classical and novel retinoids: Their targets in cancer therapy. Leukemia 16: 463-472.
-
(2002)
Leukemia
, vol.16
, pp. 463-472
-
-
Fontana, J.A.1
Rishi, A.K.2
-
10
-
-
0032841576
-
4-(hydroxyphenyl)retinamide selectively inhibits the development and progression of ductal hyperplastic lesions and carcinoma in situ in mammary gland
-
Green A, Shilkaitis A, Christov K,. 1999. 4-(hydroxyphenyl)retinamide selectively inhibits the development and progression of ductal hyperplastic lesions and carcinoma in situ in mammary gland. Carcinogenesis 20: 1535-1540.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1535-1540
-
-
Green, A.1
Shilkaitis, A.2
Christov, K.3
-
12
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
Karin M, Ben-Neriah Y,. 2000. Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity. Annu Rev Immunol 18: 621-663.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
13
-
-
0028700386
-
Clinical development plan: N-(4-hydroxyphenyl)retinamide
-
Kelloff GJ, Crowell JA, Boone CW, Steele VE, Lubet RA, Greenwald P, Alberts DS, Covey JM, Doody LA, Knapp GG, Nayfield SG, Parkinson DR, Prasad VK, Prorok PC, Sausville EV, Sigman CC,. 1994. Clinical development plan: N-(4-hydroxyphenyl)retinamide. J Cell Biochem Suppl 20: 176-196.
-
(1994)
J Cell Biochem Suppl
, vol.20
, pp. 176-196
-
-
Kelloff, G.J.1
Crowell, J.A.2
Boone, C.W.3
Steele, V.E.4
Lubet, R.A.5
Greenwald, P.6
Alberts, D.S.7
Covey, J.M.8
Doody, L.A.9
Knapp, G.G.10
Nayfield, S.G.11
Parkinson, D.R.12
Prasad, V.K.13
Prorok, P.C.14
Sausville, E.V.15
Sigman, C.C.16
-
14
-
-
80052081077
-
Celastrol inhibits breast cancer cell invasion via suppression of NF-kB-mediated matrix metalloproteinase-9 expression
-
Kim Y, Kang H, Jang SW, Ko J,. 2011. Celastrol inhibits breast cancer cell invasion via suppression of NF-kB-mediated matrix metalloproteinase-9 expression. Cell Physiol Biochem 28: 175-184.
-
(2011)
Cell Physiol Biochem
, vol.28
, pp. 175-184
-
-
Kim, Y.1
Kang, H.2
Jang, S.W.3
Ko, J.4
-
15
-
-
14944361909
-
Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential
-
Kousidou OC, Roussidis AE, Theocharis AD, Karamanos NK,. 2004. Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential. Anticancer Res 24: 4025-4030.
-
(2004)
Anticancer Res
, vol.24
, pp. 4025-4030
-
-
Kousidou, O.C.1
Roussidis, A.E.2
Theocharis, A.D.3
Karamanos, N.K.4
-
17
-
-
58849158423
-
Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-kappaB signaling pathway in human hepatocellular carcinoma cells
-
Liang JA, Wu SL, Lo HY, Hsiang CY, Ho TY,. 2009. Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-kappaB signaling pathway in human hepatocellular carcinoma cells. Mol Pharmacol 75: 151-157.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 151-157
-
-
Liang, J.A.1
Wu, S.L.2
Lo, H.Y.3
Hsiang, C.Y.4
Ho, T.Y.5
-
18
-
-
0036076333
-
FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway
-
Liu JF, Crepin M, Liu JM, Barritault D, Ledoux D,. 2002. FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway. Biochem Biophys Res Commun 293: 1174-1182.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 1174-1182
-
-
Liu, J.F.1
Crepin, M.2
Liu, J.M.3
Barritault, D.4
Ledoux, D.5
-
19
-
-
0034574498
-
The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-kB (NF-kB)
-
Magnani M, Crinelli R, Bianchi M, Antonelli A,. 2000. The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-kB (NF-kB). Curr Drug Targets 1: 387-399.
-
(2000)
Curr Drug Targets
, vol.1
, pp. 387-399
-
-
Magnani, M.1
Crinelli, R.2
Bianchi, M.3
Antonelli, A.4
-
20
-
-
12944273470
-
Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: Antitumor and antiangiogenic potential in vivo
-
Matsumoto G, Namekawa J, Muta M, Nakamura T, Bando H, Tohyama K, Toi M, Umezawa K,. 2005. Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: Antitumor and antiangiogenic potential in vivo. Clin Cancer Res 11: 1287-1293.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1287-1293
-
-
Matsumoto, G.1
Namekawa, J.2
Muta, M.3
Nakamura, T.4
Bando, H.5
Tohyama, K.6
Toi, M.7
Umezawa, K.8
-
21
-
-
0018778594
-
N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat
-
Moon RC, Thompson HJ, Becci PJ, Grubbs CJ, Gander RJ, Newton DL, Smith JM, Phillips SL, Henderson WR, Mullen LT, Brown CC, Sporn MB,. 1979. N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat. Cancer Res 39: 1339-1346.
-
(1979)
Cancer Res
, vol.39
, pp. 1339-1346
-
-
Moon, R.C.1
Thompson, H.J.2
Becci, P.J.3
Grubbs, C.J.4
Gander, R.J.5
Newton, D.L.6
Smith, J.M.7
Phillips, S.L.8
Henderson, W.R.9
Mullen, L.T.10
Brown, C.C.11
Sporn, M.B.12
-
22
-
-
0031822920
-
Retinoid-induced apoptosis in normal and neoplastic tissues
-
Nagy L, Thomazy VA, Heyman RA, Davies PJ,. 1998. Retinoid-induced apoptosis in normal and neoplastic tissues. Cell Death Differ 5: 11-19.
-
(1998)
Cell Death Differ
, vol.5
, pp. 11-19
-
-
Nagy, L.1
Thomazy, V.A.2
Heyman, R.A.3
Davies, P.J.4
-
23
-
-
0030927167
-
Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth
-
Nakshatri H, Bhat-Nakshatri P, Martin DA, Goulet RJ, Jr., Sledge GW, Jr., 1997. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth. Mol Cell Biol 17: 3629-3639.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
Goulet, Jr.R.J.4
Sledge, Jr.G.W.5
-
24
-
-
0033517999
-
Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen
-
Palayoor ST, Youmell MY, Calderwood SK, Coleman CN, Price BD,. 1999. Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene 18: 7389-7394.
-
(1999)
Oncogene
, vol.18
, pp. 7389-7394
-
-
Palayoor, S.T.1
Youmell, M.Y.2
Calderwood, S.K.3
Coleman, C.N.4
Price, B.D.5
-
25
-
-
67650141677
-
Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells
-
Park SK, Hwang YS, Park KK, Park HJ, Seo JY, Chung WY,. 2009. Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells. Carcinogenesis 30: 1225-1233.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1225-1233
-
-
Park, S.K.1
Hwang, Y.S.2
Park, K.K.3
Park, H.J.4
Seo, J.Y.5
Chung, W.Y.6
-
26
-
-
0031031930
-
Phase II chemoprevention trial of oral fenretinide in patients at risk for adenocarcinoma of the prostate
-
Pienta KJ, Esper PS, Zwas F, Krzeminski R, Flaherty LE,. 1997. Phase II chemoprevention trial of oral fenretinide in patients at risk for adenocarcinoma of the prostate. Am J Clin Oncol 20: 36-39.
-
(1997)
Am J Clin Oncol
, vol.20
, pp. 36-39
-
-
Pienta, K.J.1
Esper, P.S.2
Zwas, F.3
Krzeminski, R.4
Flaherty, L.E.5
-
28
-
-
0035328531
-
Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-kappaB in breast cancer
-
Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Traish AM, Mercurio F, Sonenshein GE,. 2001. Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-kappaB in breast cancer. Cancer Res 61: 3810-3818.
-
(2001)
Cancer Res
, vol.61
, pp. 3810-3818
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Traish, A.M.4
Mercurio, F.5
Sonenshein, G.E.6
-
29
-
-
0027439698
-
Regulatory mechanism of 92kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells
-
Sato H, Seiki M,. 1993. Regulatory mechanism of 92kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8: 395-405.
-
(1993)
Oncogene
, vol.8
, pp. 395-405
-
-
Sato, H.1
Seiki, M.2
-
30
-
-
0034955529
-
Dietary 4-HPR suppresses the development of bone metastasis in vivo in a mouse model of prostate cancer progression
-
Shaker MR, Yang G, Timme TL, Park SH, Kadmon D, Ren C, Ji X, Lee HM, Sehgal I, Anzano M, Sporn MB, Thompson TC,. 2000. Dietary 4-HPR suppresses the development of bone metastasis in vivo in a mouse model of prostate cancer progression. Clin Exp Metastasis 18: 429-438.
-
(2000)
Clin Exp Metastasis
, vol.18
, pp. 429-438
-
-
Shaker, M.R.1
Yang, G.2
Timme, T.L.3
Park, S.H.4
Kadmon, D.5
Ren, C.6
Ji, X.7
Lee, H.M.8
Sehgal, I.9
Anzano, M.10
Sporn, M.B.11
Thompson, T.C.12
-
31
-
-
0030747827
-
Enhanced degradation of I-kappaB alpha contributes to endogenous activation of NF-kappaB in Hs294T melanoma cells
-
Shattuck-Brandt RL, Richmond A,. 1997. Enhanced degradation of I-kappaB alpha contributes to endogenous activation of NF-kappaB in Hs294T melanoma cells. Cancer Res 57: 3032-3039.
-
(1997)
Cancer Res
, vol.57
, pp. 3032-3039
-
-
Shattuck-Brandt, R.L.1
Richmond, A.2
-
32
-
-
0036842110
-
Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells
-
Shimada K, Nakamura M, Ishida E, Kishi M, Yonehara S, Konishi N,. 2002. Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells. Mol Carcinog 35: 127-137.
-
(2002)
Mol Carcinog
, vol.35
, pp. 127-137
-
-
Shimada, K.1
Nakamura, M.2
Ishida, E.3
Kishi, M.4
Yonehara, S.5
Konishi, N.6
-
33
-
-
33644868276
-
N-(4-Hydroxyphenyl)retinamide and nitric oxide pro-drugs exhibit apoptotic and anti-invasive effects against bone metastatic breast cancer cells
-
Simeone AM, Colella S, Krahe R, Johnson MM, Mora E, Tari AM,. 2006. N-(4-Hydroxyphenyl)retinamide and nitric oxide pro-drugs exhibit apoptotic and anti-invasive effects against bone metastatic breast cancer cells. Carcinogenesis 27: 568-577.
-
(2006)
Carcinogenesis
, vol.27
, pp. 568-577
-
-
Simeone, A.M.1
Colella, S.2
Krahe, R.3
Johnson, M.M.4
Mora, E.5
Tari, A.M.6
-
34
-
-
0034472617
-
Matrix metalloproteinases in tumor invasion and metastasis
-
Stamenkovic I,. 2000. Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol 10: 415-433.
-
(2000)
Semin Cancer Biol
, vol.10
, pp. 415-433
-
-
Stamenkovic, I.1
-
35
-
-
46449096930
-
Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1
-
Tai KY, Shieh YS, Lee CS, Shiah SG, Wu CW,. 2008. Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1. Oncogene 27: 4044-4055.
-
(2008)
Oncogene
, vol.27
, pp. 4044-4055
-
-
Tai, K.Y.1
Shieh, Y.S.2
Lee, C.S.3
Shiah, S.G.4
Wu, C.W.5
-
36
-
-
78649668597
-
Retinoids, retinoic acid receptors, and cancer
-
Tang XH, Gudas LJ,. 2011. Retinoids, retinoic acid receptors, and cancer. Annu Rev Pathol 6: 345-364.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 345-364
-
-
Tang, X.H.1
Gudas, L.J.2
-
37
-
-
0025847582
-
Matrix metalloproteinases and their inhibitors in connective tissue remodeling
-
Woessner JF, Jr., 1991. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 5: 2145-2154.
-
(1991)
FASEB J
, vol.5
, pp. 2145-2154
-
-
Woessner, Jr.J.F.1
-
38
-
-
0034807456
-
Mechanism of fenretinide (4-HPR)-induced cell death
-
Wu JM, DiPietrantonio AM, Hsieh TC,. 2001. Mechanism of fenretinide (4-HPR)-induced cell death. Apoptosis 6: 377-388.
-
(2001)
Apoptosis
, vol.6
, pp. 377-388
-
-
Wu, J.M.1
Dipietrantonio, A.M.2
Hsieh, T.C.3
|