Fucosterol isolated from Undaria pinnatifida inhibits lipopolysaccharide- induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-κB and p38 mitogen-activated protein kinase in RAW264.7 macrophages

Food Chemistry

Volumn 135, Issue 3, 2012, Pages 967-975

  Yoo, Min Sang ^a   Shin, Ji Sun ^a,b   Choi, Hye Eun ^a   Cho, Young Wuk ^b   Bang, Myun Ho ^a   Baek, Nam In ^a   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

Fucosterol; Inflammation; MK2; MKK3 6; NF B; p38 MAPK

Indexed keywords

FUCOSTEROL; INFLAMMATION; MK2; MKK3/6; P38 MAPK;

MACROPHAGES; PHOSPHORYLATION;

NITRIC OXIDE;

CYTOKINE; FUCOSTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA BINDING; INFLAMMATION; MACROPHAGE; MEDICINAL PLANT; NONHUMAN; PROTEIN PHOSPHORYLATION; UNDARIA PINNATIFIDA;

ANIMALS; CELL LINE; CYTOKINES; DOWN-REGULATION; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; STIGMASTEROL; UNDARIA;

UNDARIA PINNATIFIDA;

EID: 84865709169     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.05.039     Document Type: Article

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