Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer

Cancer Research

Volumn 74, Issue 11, 2014, Pages 3180-3194

  Feigin, Michael E ^a   Akshinthala, S Dipikaa ^a   Araki, Kiyomi ^b   Rosenberg, Avi Z ^a   Muthuswamy, Lakshmi B ^c   Martin, Bernard ^b   Lehmann, Brian D ^e   Berman, Hal K ^b   Pietenpol, Jennifer A ^e   Cardiff, Robert D ^d   Muthuswamy, Senthil K ^a,b  

^a Simons Center for Quantitative Biology   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PROTEIN KINASE B; S6 KINASE; SCAFFOLD PROTEIN; SCRIBBLE PROTEIN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MTOR PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; SCRIB PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST TUMOR; CANCER PROGNOSIS; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL JUNCTION; CELL POLARITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE; GENE AMPLIFICATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENETIC CORRELATION; HUMAN; HUMAN CELL; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SCRIB GENE; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TUMOR DIFFERENTIATION; UPREGULATION; WILD TYPE; ANIMAL; CARCINOGENESIS; CELL LINE; FEMALE; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CARCINOGENESIS; CELL LINE; CELL LINE, TUMOR; CELL POLARITY; FEMALE; GENE EXPRESSION; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84902176984     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3415     Document Type: Article

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