메뉴 건너뛰기




Volumn 4, Issue 3, 2010, Pages 284-300

Molecular basis for therapy resistance

Author keywords

Breast cancer; Chemoresistance; Microarray; p53; Prediction

Indexed keywords

ANTHRACYCLINE; BRCA1 PROTEIN; BRCA2 PROTEIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTRADIOL; ESTROGEN RECEPTOR; FLUOROURACIL; GEFITINIB; LAPATINIB; LETROZOLE; METHOTREXATE; PACLITAXEL; PERTUZUMAB; TAMOXIFEN; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN;

EID: 77953869917     PISSN: 15747891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molonc.2010.04.005     Document Type: Review
Times cited : (36)

References (189)
  • 8
    • 77953872348 scopus 로고    scopus 로고
    • Pertuzumab and Trastuzumab: re-responses to 2 biological agents in patients with HER2-Positive breast cancer which had previously progressed during therapy with each agent given separately: a new biological and clinical observation
    • Baselga J., Cortes J., Fumoleau P., Petrella T., Gelmon K., Verma S., Pivot X., Ross G., Szado T., and Gianni L. Pertuzumab and Trastuzumab: re-responses to 2 biological agents in patients with HER2-Positive breast cancer which had previously progressed during therapy with each agent given separately: a new biological and clinical observation. Cancer Res. 69 (2009) 803S-804S
    • (2009) Cancer Res. , vol.69
    • Baselga, J.1    Cortes, J.2    Fumoleau, P.3    Petrella, T.4    Gelmon, K.5    Verma, S.6    Pivot, X.7    Ross, G.8    Szado, T.9    Gianni, L.10
  • 15
    • 6044230918 scopus 로고    scopus 로고
    • Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature
    • Bieche I., Lerebours F., Tozlu S., Espie M., Marty M., and Lidereau R. Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature. Clin. Cancer Res. 10 (2004) 6789-6795
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6789-6795
    • Bieche, I.1    Lerebours, F.2    Tozlu, S.3    Espie, M.4    Marty, M.5    Lidereau, R.6
  • 19
    • 73849107114 scopus 로고    scopus 로고
    • Neratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer
    • Bose P., and Ozer H. Neratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer. Expert Opin. Investig. Drugs 18 (2009) 1735-1751
    • (2009) Expert Opin. Investig. Drugs , vol.18 , pp. 1735-1751
    • Bose, P.1    Ozer, H.2
  • 20
    • 38549125159 scopus 로고    scopus 로고
    • Early onset of breast cancer in a group of British black women
    • Bowen R.L., Duffy S.W., Ryan D.A., Hart I.R., and Jones J.L. Early onset of breast cancer in a group of British black women. Br. J. Cancer 98 (2008) 277-281
    • (2008) Br. J. Cancer , vol.98 , pp. 277-281
    • Bowen, R.L.1    Duffy, S.W.2    Ryan, D.A.3    Hart, I.R.4    Jones, J.L.5
  • 26
    • 75749123113 scopus 로고    scopus 로고
    • Targeted chemotherapy? Platinum in BRCA1-dysfunctional breast cancer
    • Carey L.A. Targeted chemotherapy? Platinum in BRCA1-dysfunctional breast cancer. J. Clin. Oncol. 28 (2010) 361-363
    • (2010) J. Clin. Oncol. , vol.28 , pp. 361-363
    • Carey, L.A.1
  • 29
    • 69249115697 scopus 로고    scopus 로고
    • Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations
    • Carter H., Chen S.N., Isik L., Tyekucheva S., Velculescu V.E., Kinzler K.W., Vogelstein B., and Karchin R. Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. Cancer Res. 69 (2009) 6660-6667
    • (2009) Cancer Res. , vol.69 , pp. 6660-6667
    • Carter, H.1    Chen, S.N.2    Isik, L.3    Tyekucheva, S.4    Velculescu, V.E.5    Kinzler, K.W.6    Vogelstein, B.7    Karchin, R.8
  • 34
  • 36
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh M.A., Vogel C.L., Tripathy D., Robert N.J., Scholl S., Fehrenbacher L., Wolter J.M., Paton V., Shak S., Lieberman G., and Slamon D.J. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J. Clin. Oncol. 17 (1999) 2639-2648
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.M.7    Paton, V.8    Shak, S.9    Lieberman, G.10    Slamon, D.J.11
  • 39
    • 0026071630 scopus 로고
    • A comparative study of histopathology, hormone receptors, peanut lectin binding, Ki-6 immunostaining, and nucleolar organizer region-associated proteins in human breast cancer
    • Di Stefano D., Mingazzini P.L., Scucchi L., Donnetti M., and Marinozzi V. A comparative study of histopathology, hormone receptors, peanut lectin binding, Ki-6 immunostaining, and nucleolar organizer region-associated proteins in human breast cancer. Cancer 67 (1991) 463-471
    • (1991) Cancer , vol.67 , pp. 463-471
    • Di Stefano, D.1    Mingazzini, P.L.2    Scucchi, L.3    Donnetti, M.4    Marinozzi, V.5
  • 40
    • 0020665398 scopus 로고
    • Endocrine consequences of CMF adjuvant therapy in premenopausal and postmenopausal breast cancer patients
    • Dnistrian A.M., Schwartz M.K., Fracchia A.A., Kaufman R.J., Hakes T.B., and Currie V.E. Endocrine consequences of CMF adjuvant therapy in premenopausal and postmenopausal breast cancer patients. Cancer 51 (1983) 803-807
    • (1983) Cancer , vol.51 , pp. 803-807
    • Dnistrian, A.M.1    Schwartz, M.K.2    Fracchia, A.A.3    Kaufman, R.J.4    Hakes, T.B.5    Currie, V.E.6
  • 43
    • 3843116922 scopus 로고    scopus 로고
    • "Good Old" clinical markers have similar power in breast cancer prognosis as microarray gene expression profilers
    • Ed, én P., Ritz C., Rose C., Fernö M., and Peterson C. "Good Old" clinical markers have similar power in breast cancer prognosis as microarray gene expression profilers. Eur. J. Cancer 40 (2004) 1837-1841
    • (2004) Eur. J. Cancer , vol.40 , pp. 1837-1841
    • Ed1    én, P.2    Ritz, C.3    Rose, C.4    Fernö, M.5    Peterson, C.6
  • 45
    • 13444282534 scopus 로고    scopus 로고
    • Outcome signature genes in breast cancer: is there a unique set?
    • Ein-Dor L., Kela I., Getz G., Givol D., and Domany E. Outcome signature genes in breast cancer: is there a unique set?. Bioinformatics 21 (2005) 171-178
    • (2005) Bioinformatics , vol.21 , pp. 171-178
    • Ein-Dor, L.1    Kela, I.2    Getz, G.3    Givol, D.4    Domany, E.5
  • 46
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial
    • Ellis M.J., Coop A., Singh B., Mauriac L., LlombertCussac A., Janicke F., Miller W.R., Evans D.B., Dugan M., Brady C., QuebeFehling E., and Borgs M. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial. J. Clin. Oncol. 19 (2001) 3808-3816
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3    Mauriac, L.4    LlombertCussac, A.5    Janicke, F.6    Miller, W.R.7    Evans, D.B.8    Dugan, M.9    Brady, C.10    QuebeFehling, E.11    Borgs, M.12
  • 51
    • 0020555461 scopus 로고
    • Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer
    • Fisher B., Bauer M., Wickerham D.L., Redmond C.K., and Fisher E.R. Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. Cancer 52 (1983) 1551-1557
    • (1983) Cancer , vol.52 , pp. 1551-1557
    • Fisher, B.1    Bauer, M.2    Wickerham, D.L.3    Redmond, C.K.4    Fisher, E.R.5
  • 52
    • 0024044464 scopus 로고
    • Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: findings from national surgical adjuvant breast and bowel project protocol B-06
    • Fisher B., Redmond C., Fisher E.R., and Caplan R. Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: findings from national surgical adjuvant breast and bowel project protocol B-06. J. Clin. Oncol. 6 (1988) 1076-1087
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1076-1087
    • Fisher, B.1    Redmond, C.2    Fisher, E.R.3    Caplan, R.4
  • 53
    • 0037103104 scopus 로고    scopus 로고
    • Pathobiology of preoperative chemotherapy - Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-18
    • Fisher E.R., Wang J.P., Bryant J., Fisher B., Mamounas E., and Wolmark N. Pathobiology of preoperative chemotherapy - Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-18. Cancer 95 (2002) 681-695
    • (2002) Cancer , vol.95 , pp. 681-695
    • Fisher, E.R.1    Wang, J.P.2    Bryant, J.3    Fisher, B.4    Mamounas, E.5    Wolmark, N.6
  • 54
    • 70349952517 scopus 로고    scopus 로고
    • Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors
    • Flageng M.H., Moi L.L.H., Dixon J.M., Geisler J., Lien E.A., Miller W.R., Lonning P.E., and Mellgren G. Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. Br. J. Cancer 101 (2009) 1253-1260
    • (2009) Br. J. Cancer , vol.101 , pp. 1253-1260
    • Flageng, M.H.1    Moi, L.L.H.2    Dixon, J.M.3    Geisler, J.4    Lien, E.A.5    Miller, W.R.6    Lonning, P.E.7    Mellgren, G.8
  • 57
    • 0035866772 scopus 로고    scopus 로고
    • Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
    • Geisler S., Lønning P.E., Aas T., Johnsen H., Fluge O., Haugen D.F., Lillehaug J.R., Akslen L.A., and Borresen-Dale A.L. Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer. Cancer Res. 61 (2001) 2505-2512
    • (2001) Cancer Res. , vol.61 , pp. 2505-2512
    • Geisler, S.1    Lønning, P.E.2    Aas, T.3    Johnsen, H.4    Fluge, O.5    Haugen, D.F.6    Lillehaug, J.R.7    Akslen, L.A.8    Borresen-Dale, A.L.9
  • 63
    • 58849100464 scopus 로고    scopus 로고
    • Do 'basal-like' breast cancers really exist?
    • Gusterson B. Do 'basal-like' breast cancers really exist?. Nat. Rev. Cancer 9 (2009) 128-134
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 128-134
    • Gusterson, B.1
  • 67
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey J.M., Clark G.M., Osborne C.K., and Allred D.C. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J. Clin. Oncol. 17 (1999) 1474-1481
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 77
    • 0033870292 scopus 로고    scopus 로고
    • Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
    • Jarvinen T.A.H., Tanner M., Rantanen V., Barlund M., Borg A., Grenman S., and Isola J. Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am. J. Pathol. 156 (2000) 839-847
    • (2000) Am. J. Pathol. , vol.156 , pp. 839-847
    • Jarvinen, T.A.H.1    Tanner, M.2    Rantanen, V.3    Barlund, M.4    Borg, A.5    Grenman, S.6    Isola, J.7
  • 79
    • 0019138155 scopus 로고
    • Estrogen receptor status and response to polychemotherapy in advanced breast cancer
    • Jonat W., Maass H., Stolzenbach G., and Trams G. Estrogen receptor status and response to polychemotherapy in advanced breast cancer. Cancer 46 (1980) 2809-2813
    • (1980) Cancer , vol.46 , pp. 2809-2813
    • Jonat, W.1    Maass, H.2    Stolzenbach, G.3    Trams, G.4
  • 80
    • 46449134193 scopus 로고    scopus 로고
    • The 38th David A. Karnofsky lecture: the paradoxical actions of estrogen in breast cancer - survival or death?
    • Jordan V.C. The 38th David A. Karnofsky lecture: the paradoxical actions of estrogen in breast cancer - survival or death?. J. Clin. Oncol. 26 (2008) 3073-3082
    • (2008) J. Clin. Oncol. , vol.26 , pp. 3073-3082
    • Jordan, V.C.1
  • 81
    • 65349101151 scopus 로고    scopus 로고
    • Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941
    • Junttila T.T., Akita R.W., Parsons K., Fields C., Phillips G.D.L., Friedman L.S., Sampath D., and Sliwkowski M.X. Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941. Cancer Cell 15 (2009) 429-440
    • (2009) Cancer Cell , vol.15 , pp. 429-440
    • Junttila, T.T.1    Akita, R.W.2    Parsons, K.3    Fields, C.4    Phillips, G.D.L.5    Friedman, L.S.6    Sampath, D.7    Sliwkowski, M.X.8
  • 83
    • 33344462540 scopus 로고    scopus 로고
    • Mutation of the PIK3CA oncogene in human cancers
    • Karakas B., Bachman K.E., and Park B.H. Mutation of the PIK3CA oncogene in human cancers. Br. J. Cancer 94 (2006) 455-459
    • (2006) Br. J. Cancer , vol.94 , pp. 455-459
    • Karakas, B.1    Bachman, K.E.2    Park, B.H.3
  • 84
    • 66149093901 scopus 로고    scopus 로고
    • Lapatinib monotherapy in patients with HER2-overexpressing relapsed or refractory inflammatory breast cancer: final results and survival of the expanded HER2+cohort in EGF103009, a phase II study
    • Kaufman B., Trudeau M., Awada A., Blackwell K., Bachelot T., Salazar V., DeSilvio M., Westlund R., Zaks T., Spector N., and Johnston S. Lapatinib monotherapy in patients with HER2-overexpressing relapsed or refractory inflammatory breast cancer: final results and survival of the expanded HER2+cohort in EGF103009, a phase II study. Lancet Oncol. 10 (2009) 581-588
    • (2009) Lancet Oncol. , vol.10 , pp. 581-588
    • Kaufman, B.1    Trudeau, M.2    Awada, A.3    Blackwell, K.4    Bachelot, T.5    Salazar, V.6    DeSilvio, M.7    Westlund, R.8    Zaks, T.9    Spector, N.10    Johnston, S.11
  • 86
    • 32944475493 scopus 로고    scopus 로고
    • Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
    • Knoop A.S., Knudsen H., Balslev E., Rasmussen B.B., Overgaard J., Nielsen K.V., Schonau A., Gunnarsdottir K., Olsen K.E., Mouridsen H., and Ejlertsen B. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group. J. Clin. Oncol. 23 (2005) 7483-7490
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7483-7490
    • Knoop, A.S.1    Knudsen, H.2    Balslev, E.3    Rasmussen, B.B.4    Overgaard, J.5    Nielsen, K.V.6    Schonau, A.7    Gunnarsdottir, K.8    Olsen, K.E.9    Mouridsen, H.10    Ejlertsen, B.11
  • 89
    • 67650688104 scopus 로고    scopus 로고
    • The majority of triple-negative breast cancer may correspond to basal-like carcinoma, but triple-negative breast cancer is not identical to basal-like carcinoma
    • Kuroda N., Ohara M., Inoue K., Mizuno K., Fujishima N., Hamaguchi N., and Lee G.-H. The majority of triple-negative breast cancer may correspond to basal-like carcinoma, but triple-negative breast cancer is not identical to basal-like carcinoma. Med. Mol. Morphol. 42 (2009) 128-131
    • (2009) Med. Mol. Morphol. , vol.42 , pp. 128-131
    • Kuroda, N.1    Ohara, M.2    Inoue, K.3    Mizuno, K.4    Fujishima, N.5    Hamaguchi, N.6    Lee, G.-H.7
  • 90
    • 0022218452 scopus 로고
    • Relationship of flow cytometry results to clinical and steroid receptor status in human breast cancer
    • Kute T.E., Muss H.B., Hopkins M., Marshall R., Case D., and Kammire L. Relationship of flow cytometry results to clinical and steroid receptor status in human breast cancer. Breast Cancer Res. 6 (1985) 113-121
    • (1985) Breast Cancer Res. , vol.6 , pp. 113-121
    • Kute, T.E.1    Muss, H.B.2    Hopkins, M.3    Marshall, R.4    Case, D.5    Kammire, L.6
  • 92
    • 74049104166 scopus 로고    scopus 로고
    • Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit?
    • Lewis-Wambi J.S., and Jordan V.C. Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit?. Breast Cancer Res. 11 (2009)
    • (2009) Breast Cancer Res. , vol.11
    • Lewis-Wambi, J.S.1    Jordan, V.C.2
  • 96
    • 55849132481 scopus 로고    scopus 로고
    • Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer high incidence of central nervous system metastases
    • Lin N.U., Claus E., Sohl J., Razzak A.R., Arnaout A., and Winer E.P. Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer high incidence of central nervous system metastases. Cancer 113 (2008) 2638-2645
    • (2008) Cancer , vol.113 , pp. 2638-2645
    • Lin, N.U.1    Claus, E.2    Sohl, J.3    Razzak, A.R.4    Arnaout, A.5    Winer, E.P.6
  • 97
    • 0017102124 scopus 로고
    • The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture
    • Lippman M., Bolan G., and Huff K. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res. 36 (1976) 4595-4601
    • (1976) Cancer Res. , vol.36 , pp. 4595-4601
    • Lippman, M.1    Bolan, G.2    Huff, K.3
  • 101
    • 51449113045 scopus 로고    scopus 로고
    • Targeted therapy for cancer using PARP inhibitors
    • Lord C.J., and Ashworth A. Targeted therapy for cancer using PARP inhibitors. Curr. Opin. Pharmacol. 8 (2008) 363-369
    • (2008) Curr. Opin. Pharmacol. , vol.8 , pp. 363-369
    • Lord, C.J.1    Ashworth, A.2
  • 102
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe S.W., Ruley H.E., Jacks T., and Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74 (1993) 957-967
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 103
    • 0035151327 scopus 로고    scopus 로고
    • Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: Results from a nationwide study
    • Lundin J., Lundin M., Holli K., Kataja V., Elomaa L., Pylkkanen L., TurpeenniemiHujanen T., and Joensuu H. Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: Results from a nationwide study. J. Clin. Oncol. 19 (2001) 28-36
    • (2001) J. Clin. Oncol. , vol.19 , pp. 28-36
    • Lundin, J.1    Lundin, M.2    Holli, K.3    Kataja, V.4    Elomaa, L.5    Pylkkanen, L.6    TurpeenniemiHujanen, T.7    Joensuu, H.8
  • 104
    • 0037338906 scopus 로고    scopus 로고
    • Study of suboptimum treatment response: lessons from breast cancer
    • Lønning P. Study of suboptimum treatment response: lessons from breast cancer. Lancet Oncol. 4 (2003) 177-185
    • (2003) Lancet Oncol. , vol.4 , pp. 177-185
    • Lønning, P.1
  • 105
    • 1442348266 scopus 로고    scopus 로고
    • Genes causing inherited cancer as beacons identifying the mechanisms of chemoresistance
    • Lønning P.E. Genes causing inherited cancer as beacons identifying the mechanisms of chemoresistance. Trends Mol. Med. 10 (2004) 113-118
    • (2004) Trends Mol. Med. , vol.10 , pp. 113-118
    • Lønning, P.E.1
  • 106
    • 38549159170 scopus 로고    scopus 로고
    • Breast cancer prognostication and prediction; are we making progress?
    • Lønning P.E. Breast cancer prognostication and prediction; are we making progress?. Ann. Oncol. 18 Suppl 8 (2007) viii3-viii7
    • (2007) Ann. Oncol. , vol.18 , Issue.SUPPL. 8
    • Lønning, P.E.1
  • 108
    • 0029566969 scopus 로고
    • Mechanisms of action of endocrine treatment in breast cancer
    • Lønning P.E., and Lien E. Mechanisms of action of endocrine treatment in breast cancer. Crit. Rev. Oncol./Haematol. 21 (1995) 158-193
    • (1995) Crit. Rev. Oncol./Haematol. , vol.21 , pp. 158-193
    • Lønning, P.E.1    Lien, E.2
  • 113
    • 0028853923 scopus 로고
    • Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells
    • Masamura S., Santner S.J., Heitjan D.F., and Santen R.J. Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells. J. Clin. Endocrinol. Metab. 80 (1995) 2918-2925
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 2918-2925
    • Masamura, S.1    Santner, S.J.2    Heitjan, D.F.3    Santen, R.J.4
  • 117
    • 73949150777 scopus 로고    scopus 로고
    • Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer
    • Moelans C.B., de Weger R.A., van Blokland M.T.M., van der Wall E., and van Diest P.J. Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer. Mod. Pathol. 23 (2010) 62-70
    • (2010) Mod. Pathol. , vol.23 , pp. 62-70
    • Moelans, C.B.1    de Weger, R.A.2    van Blokland, M.T.M.3    van der Wall, E.4    van Diest, P.J.5
  • 118
    • 0021226037 scopus 로고
    • Correlation of cell-cycle kinetics, hormone receptors, histopathology, and nodal status in human breast cancer
    • Moran R.E., Black M.M., Alpert L., and Straus M.J. Correlation of cell-cycle kinetics, hormone receptors, histopathology, and nodal status in human breast cancer. Cancer 54 (1984) 1586-1590
    • (1984) Cancer , vol.54 , pp. 1586-1590
    • Moran, R.E.1    Black, M.M.2    Alpert, L.3    Straus, M.J.4
  • 120
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment
    • Normanno N., Bianco C., De Luca A., Maiello M.R., and Salomon D.S. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr. Relat. Cancer 10 (2003) 1-21
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3    Maiello, M.R.4    Salomon, D.S.5
  • 123
    • 68449096428 scopus 로고    scopus 로고
    • Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial
    • Abstr 3
    • O'Shaugnessy J., Osborne C., Pippen J., Yoffe M., Patt D., Monaghan G., Rocha C., Ossovskaya V., Sherman B., and Bradley C. Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial. J. Clin. Oncol. (Suppl.) 27 (2009) 793S Abstr 3
    • (2009) J. Clin. Oncol. (Suppl.) , vol.27
    • O'Shaugnessy, J.1    Osborne, C.2    Pippen, J.3    Yoffe, M.4    Patt, D.5    Monaghan, G.6    Rocha, C.7    Ossovskaya, V.8    Sherman, B.9    Bradley, C.10
  • 124
    • 0142211270 scopus 로고    scopus 로고
    • A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival
    • Ogston K.N., Miller I.D., Payne S., Hutcheon A.W., Sarkar T.K., Smith I., Schofield A., and Heys S.D. A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival. Breast 12 (2003) 320-327
    • (2003) Breast , vol.12 , pp. 320-327
    • Ogston, K.N.1    Miller, I.D.2    Payne, S.3    Hutcheon, A.W.4    Sarkar, T.K.5    Smith, I.6    Schofield, A.7    Heys, S.D.8
  • 130
    • 0030870295 scopus 로고    scopus 로고
    • The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells
    • Pegram M.D., Finn R.S., Arzoo K., Beryt M., Pietras R.J., and Slamon D.J. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 15 (1997) 537-547
    • (1997) Oncogene , vol.15 , pp. 537-547
    • Pegram, M.D.1    Finn, R.S.2    Arzoo, K.3    Beryt, M.4    Pietras, R.J.5    Slamon, D.J.6
  • 133
    • 0034896257 scopus 로고    scopus 로고
    • Chemotherapy response of breast cancer depends on HER-status and antracycline dose intensity in the neoadjuvant setting
    • Petit T., Borel C., Ghnassia J.-P., Rodier J.-F., Escande A., Mors R., and Haegelé P. Chemotherapy response of breast cancer depends on HER-status and antracycline dose intensity in the neoadjuvant setting. Clin. Cancer Res. 7 (2001) 1577-1581
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1577-1581
    • Petit, T.1    Borel, C.2    Ghnassia, J.-P.3    Rodier, J.-F.4    Escande, A.5    Mors, R.6    Haegelé, P.7
  • 137
    • 30544434252 scopus 로고    scopus 로고
    • Topoisomerase II-alpha gene amplification as a predictor of responsiveness to anthracycline-containing chemotherapy in the Cancer International Research Group 006 clinical trial of trastuzumqab (herceptin) in the adjuvant setting
    • Abstr 1045
    • Press M.F., Bernstein L., Sauter G., Zhou J.Y., Eiermann W., Pienkowski T., Crown J., Robert N., Bee V., Taupin H., Villalobos J., Seelig S., Pegram M., and Slamon D. Topoisomerase II-alpha gene amplification as a predictor of responsiveness to anthracycline-containing chemotherapy in the Cancer International Research Group 006 clinical trial of trastuzumqab (herceptin) in the adjuvant setting. Breast Cancer Res. Treat. 94 (2005) S54 Abstr 1045
    • (2005) Breast Cancer Res. Treat. , vol.94
    • Press, M.F.1    Bernstein, L.2    Sauter, G.3    Zhou, J.Y.4    Eiermann, W.5    Pienkowski, T.6    Crown, J.7    Robert, N.8    Bee, V.9    Taupin, H.10    Villalobos, J.11    Seelig, S.12    Pegram, M.13    Slamon, D.14
  • 144
    • 12344277756 scopus 로고    scopus 로고
    • Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer
    • Ring A.E., Smith I.E., Ashley S., Fulford L.G., and Lakhani S.R. Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. Br. J. Cancer 91 (2004) 2012-2017
    • (2004) Br. J. Cancer , vol.91 , pp. 2012-2017
    • Ring, A.E.1    Smith, I.E.2    Ashley, S.3    Fulford, L.G.4    Lakhani, S.R.5
  • 155
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., and McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235 (1987) 177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 164
    • 43249097005 scopus 로고    scopus 로고
    • Low-dose estrogen therapy to reverse acquired antihormonal resistance in the treatment of breast cancer
    • Swaby R.F., and Jordan V.C. Low-dose estrogen therapy to reverse acquired antihormonal resistance in the treatment of breast cancer. Clin. Breast Cancer 8 (2008) 124-133
    • (2008) Clin. Breast Cancer , vol.8 , pp. 124-133
    • Swaby, R.F.1    Jordan, V.C.2
  • 167
    • 33745834662 scopus 로고    scopus 로고
    • Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
    • Sørlie T., Wang Y.L., Xiao C.L., Johnsen H., Naume B., Samaha R.R., and Borresen-Dale A.L. Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms. BMC Genomics 7 (2006)
    • (2006) BMC Genomics , vol.7
    • Sørlie, T.1    Wang, Y.L.2    Xiao, C.L.3    Johnsen, H.4    Naume, B.5    Samaha, R.R.6    Borresen-Dale, A.L.7
  • 168
    • 47549107072 scopus 로고    scopus 로고
    • Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
    • Tan D.S.P., Marchio C., Jones R.L., Savage K., Smith I.E., Dowsett M., and Reis J.S. Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. Breast Cancer Res. Treat. 111 (2008) 27-44
    • (2008) Breast Cancer Res. Treat. , vol.111 , pp. 27-44
    • Tan, D.S.P.1    Marchio, C.2    Jones, R.L.3    Savage, K.4    Smith, I.E.5    Dowsett, M.6    Reis, J.S.7
  • 170
    • 33744969590 scopus 로고    scopus 로고
    • Topoisomerase II alpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401
    • Tanner M., Isola J., Wiklund T., Erikstein B., Kellokumpu-Lehtinen P., Malmstrom P., Wilking N., Nilsson J., and Bergh J. Topoisomerase II alpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. J. Clin. Oncol. 24 (2006) 2428-2436
    • (2006) J. Clin. Oncol. , vol.24 , pp. 2428-2436
    • Tanner, M.1    Isola, J.2    Wiklund, T.3    Erikstein, B.4    Kellokumpu-Lehtinen, P.5    Malmstrom, P.6    Wilking, N.7    Nilsson, J.8    Bergh, J.9
  • 179
    • 0037096869 scopus 로고    scopus 로고
    • Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma
    • Wang J.Z., Buchholz T.A., Middleton L.P., Allred D.C., Tucker S.L., Kuerer H.M., Esteva F.J., Hortobagyi G.N., and Sahin A.A. Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma. Cancer 94 (2002) 3107-3114
    • (2002) Cancer , vol.94 , pp. 3107-3114
    • Wang, J.Z.1    Buchholz, T.A.2    Middleton, L.P.3    Allred, D.C.4    Tucker, S.L.5    Kuerer, H.M.6    Esteva, F.J.7    Hortobagyi, G.N.8    Sahin, A.A.9
  • 181
    • 0018093599 scopus 로고
    • Estrogen receptors and response of breast cancer to chemotherapy
    • Webster D.J.T., Bronn D.G., and Minton J.P. Estrogen receptors and response of breast cancer to chemotherapy. N. Engl. J. Med. 299 (1978) 604-605
    • (1978) N. Engl. J. Med. , vol.299 , pp. 604-605
    • Webster, D.J.T.1    Bronn, D.G.2    Minton, J.P.3
  • 182
    • 0036895886 scopus 로고    scopus 로고
    • Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors
    • Wessels L.F.A., van Welsem T., Hart A.A.M., van't Veer L.J., Reinders M.J.T., and Nederlof P.M. Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors. Cancer Res. 62 (2002) 7110-7117
    • (2002) Cancer Res. , vol.62 , pp. 7110-7117
    • Wessels, L.F.A.1    van Welsem, T.2    Hart, A.A.M.3    van't Veer, L.J.4    Reinders, M.J.T.5    Nederlof, P.M.6
  • 187
    • 77953873255 scopus 로고    scopus 로고
    • Immunohistochemical expression of PTEN and phosphorylated Akt are not correlated with clinical outcome in breast cancer patients treated with trastuzumab-containing neo-adjuvant chemotherapy
    • Yonemori K., Tsuta K., Shimizu C., Hatanaka Y., Hashizume K., Ono M., Kouno T., Ando M., Tamura K., Katsumata N., Hasegawa T., Kinoshita T., and Fujiwara Y. Immunohistochemical expression of PTEN and phosphorylated Akt are not correlated with clinical outcome in breast cancer patients treated with trastuzumab-containing neo-adjuvant chemotherapy. Med. Oncol. 26 (2009) 344-349
    • (2009) Med. Oncol. , vol.26 , pp. 344-349
    • Yonemori, K.1    Tsuta, K.2    Shimizu, C.3    Hatanaka, Y.4    Hashizume, K.5    Ono, M.6    Kouno, T.7    Ando, M.8    Tamura, K.9    Katsumata, N.10    Hasegawa, T.11    Kinoshita, T.12    Fujiwara, Y.13
  • 189
    • 34548462552 scopus 로고    scopus 로고
    • Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells
    • Yue W., Fan P., Wang J.P., Li Y.B., and Santen R.J. Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. J. Steroid Biochem. Mol. Biol. 106 (2007) 102-110
    • (2007) J. Steroid Biochem. Mol. Biol. , vol.106 , pp. 102-110
    • Yue, W.1    Fan, P.2    Wang, J.P.3    Li, Y.B.4    Santen, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.