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Volumn 15, Issue 4, 2014, Pages 199-209

Relevance of single-nucleotide polymorphisms in human TLR genes to infectious and inflammatory diseases and cancer

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 11; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

EID: 84902115681     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2014.10     Document Type: Review
Times cited : (51)

References (114)
  • 1
    • 34249732658 scopus 로고    scopus 로고
    • Role of the innate immune system in host defence against bacterial infections: Focus on the Toll-like receptors
    • DOI 10.1111/j.1365-2796.2007.01821.x
    • Albiger B, Dahlberg S, Henriques-Normark B, Normark S. Role of the innate immune system in host defence against bacterial infections: Focus on the Tolllike receptors. J Intern Med 2007; 261: 511-528. (Pubitemid 46835986
    • (2007) Journal of Internal Medicine , vol.261 , Issue.6 , pp. 511-528
    • Albiger, B.1    Dahlberg, S.2    Henriques-Normark, B.3    Normark, S.4
  • 3
    • 0034456693 scopus 로고    scopus 로고
    • Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
    • Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: Gene structure, expression, and evolution. Eur Cytokine Netw 2000; 11: 362-371. (Pubitemid 32268893
    • (2000) European Cytokine Network , vol.11 , Issue.3 , pp. 362-371
    • Du, X.1    Poltorak, A.2    Wei, Y.3    Beutler, B.4
  • 4
    • 0035911644 scopus 로고    scopus 로고
    • Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells
    • DOI 10.1016/S0167-4781(00)00289-X, PII S016747810000289X
    • Chuang T, Ulevitch RJ. Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells. Biochim Biophys Acta 2001; 1518: 157-161. (Pubitemid 32232289
    • (2001) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1518 , Issue.1-2 , pp. 157-161
    • Chuang, T.-H.1    Ulevitch, R.J.2
  • 5
    • 1542377424 scopus 로고    scopus 로고
    • A toll-like receptor that prevent infection by uropathogenic bacteria
    • DOI 10.1126/science.1094351
    • Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavell RA et al. A tolllike receptor that prevents infection by uropathogenic bacteria. Science 2004; 303: 1522-1526. (Pubitemid 38314423
    • (2004) Science , vol.303 , Issue.5663 , pp. 1522-1526
    • Zhang, D.1    Zhang, G.2    Hayden, M.S.3    Greenblatt, M.B.4    Bussey, C.5    Flavell, R.A.6    Ghosh, S.7
  • 7
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • DOI 10.1038/35099560
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3. Nature 2001; 413: 732-738. (Pubitemid 33009951
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 9
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999; 274: 10689-10692
    • (1999) J Biol Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 12
    • 34547535297 scopus 로고    scopus 로고
    • Mechanisms of disease: Toll-like receptors in cardiovascular disease
    • DOI 10.1038/ncpcardio0938, PII NCPCARDIO0938
    • Frantz S, Ertl G, Bauersachs J. Mechanisms of disease: Toll-like receptors in cardiovascular disease. Nat Clin Pract Cardiovasc Med 2007; 4: 444-454. (Pubitemid 47180328
    • (2007) Nature Clinical Practice Cardiovascular Medicine , vol.4 , Issue.8 , pp. 444-454
    • Frantz, S.1    Ertl, G.2    Bauersachs, J.3
  • 13
    • 33751436631 scopus 로고    scopus 로고
    • Fat uses a TOLL-road to connect inflammation and diabetes
    • DOI 10.1016/j.cmet.2006.11.008, PII S1550413106003706
    • Kim JK. Fat uses a TOLL - road to connect inflammation and diabetes. Cell Metab 2006; 4: 417-419. (Pubitemid 44817355
    • (2006) Cell Metabolism , vol.4 , Issue.6 , pp. 417-419
    • Kim, J.K.1
  • 15
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004; 118: 229-241. (Pubitemid 38962578
    • (2004) Cell , vol.118 , Issue.2 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 16
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product
    • Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product. J Immunol 1999; 162: 3749-3752. (Pubitemid 29314747
    • (1999) Journal of Immunology , vol.162 , Issue.7 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 18
    • 0036954037 scopus 로고    scopus 로고
    • Recognition of lipopeptides by Toll-like receptors
    • DOI 10.1179/096805102125001073
    • Takeda K, Takeuchi O, Akira S. Recognition of lipopeptides by Toll-like receptors. J Endotoxin Res 2002; 8: 459-463. (Pubitemid 36104601
    • (2002) Journal of Endotoxin Research , vol.8 , Issue.6 , pp. 459-463
    • Takeda, K.1    Takeuchi, O.2    Akira, S.3
  • 19
    • 33645505320 scopus 로고    scopus 로고
    • Interactions of sequence variants in interleukin-1 receptor-Associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk
    • Sun J, Wiklund F, Hsu FC, Bailter K, Zheng SL, Johansson JE et al. Interactions of sequence variants in interleukin-1 receptor-Associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2006; 15: 480-485
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 480-485
    • Sun, J.1    Wiklund, F.2    Hsu, F.C.3    Bailter, K.4    Zheng, S.L.5    Johansson, J.E.6
  • 22
    • 84872372112 scopus 로고    scopus 로고
    • A frequent Toll-like receptor 1 gene polymorphism affects NK- And T-cell INF-g production and is associated with Helicobacter pylori-induced gastric disease
    • Yang CA, Scheibenbogen C, Bauer S, Kleinle C, Wex T, Bornschein J et al. A frequent Toll-like receptor 1 gene polymorphism affects NK- And T-cell INF-g production and is associated with Helicobacter pylori-induced gastric disease. Helicobacter 2013; 18: 13-21
    • (2013) Helicobacter , vol.18 , pp. 13-21
    • Yang, C.A.1    Scheibenbogen, C.2    Bauer, S.3    Kleinle, C.4    Wex, T.5    Bornschein, J.6
  • 23
    • 34248381345 scopus 로고    scopus 로고
    • The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components
    • Omueti KO, Mazur DJ, Thompson KS, Lyle EA, Tapping RI. The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components. J Immunol 2007; 178: 6387-6394. (Pubitemid 46729197
    • (2007) Journal of Immunology , vol.178 , Issue.10 , pp. 6387-6394
    • Omueti, K.O.1    Mazur, D.J.2    Thompson, K.S.3    Lyle, E.A.4    Tapping, R.I.5
  • 24
    • 0033794461 scopus 로고    scopus 로고
    • A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection
    • Lorenz E, Mira JP, Cornish KL, Arbour NC, Schwartz DA. A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect Immun 2000; 68: 6398-6401
    • (2000) Infect Immun , vol.68 , pp. 6398-6401
    • Lorenz, E.1    Mira, J.P.2    Cornish, K.L.3    Arbour, N.C.4    Schwartz, D.A.5
  • 27
    • 36248986638 scopus 로고    scopus 로고
    • Association of TLR2 gene Arg753Gln polymorphism with urinary tract infection in children
    • DOI 10.1111/j.1744-313X.2007.00709.x
    • Tabel Y, Berdeli A, Mir S. Association of TLR2 gene Arg753Gln polymorphism with urinary tract infection in children. Int J Immunogenet 2007; 34: 399-405. (Pubitemid 350126007
    • (2007) International Journal of Immunogenetics , vol.34 , Issue.6 , pp. 399-405
    • Tabel, Y.1    Berdeli, A.2    Mir, S.3
  • 28
    • 34547688764 scopus 로고    scopus 로고
    • Arg753Gln polymorphism of the human toll-like receptor-2 gene in children with recurrent febrile infections
    • DOI 10.1007/s10528-007-9091-0
    • Kutukculer N, Yeniay BS, Aksu G, Berdeli A. Arg753Gln polymorphism of the human toll-like receptor-2 gene in children with recurrent febrile infections. Biochem Genet 2007; 45: 507-514. (Pubitemid 47222802
    • (2007) Biochemical Genetics , vol.45 , Issue.7-8 , pp. 507-514
    • Kutukculer, N.1    Yeniay, B.S.2    Aksu, G.3    Berdeli, A.4
  • 29
    • 23744442371 scopus 로고    scopus 로고
    • TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children
    • DOI 10.1007/s00109-005-0677-x
    • Berdeli A, Celik HA, Ozyürek R, Dogrusoz B, Aydin HH. TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children. J Mol Med 2005; 83: 535-541. (Pubitemid 41126069
    • (2005) Journal of Molecular Medicine , vol.83 , Issue.7 , pp. 535-541
    • Berdeli, A.1    Celik, H.A.2    Ozyurek, R.3    Dogrusoz, B.4    Aydin, H.H.5
  • 32
    • 14544306143 scopus 로고    scopus 로고
    • Association of the polymorphism for toll-like receptor 2 with type 1 diabetes susceptibility
    • DOI 10.1196/annals.1337.028
    • Park Y, Park S, Yoo E, Kim D, Shin H. Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility. Ann NY Acad Sci 2004; 1037: 170-174. (Pubitemid 40299762
    • (2004) Annals of the New York Academy of Sciences , vol.1037 , pp. 170-174
    • Park, Y.1    Park, S.2    Yoo, E.3    Kim, D.4    Shin, H.5
  • 33
    • 34548189060 scopus 로고    scopus 로고
    • Association between toll-like receptor polymorphisms and the outcome of liver transplantation for chronic hepatitis C virus
    • DOI 10.1097/01.tp.0000276960.35313.bf, PII 0000789020070827000012
    • Eid AJ, Brown RA, Paya CV, Razonable RR. Association between toll-like receptor polymorphisms and the outcome of liver transplantation for chronic hepatitis C virus. Transplantation 2007; 84: 511-516. (Pubitemid 47312163
    • (2007) Transplantation , vol.84 , Issue.4 , pp. 511-516
    • Eid, A.J.1    Brown, R.A.2    Paya, C.V.3    Razonable, R.R.4
  • 34
    • 34248190825 scopus 로고    scopus 로고
    • Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation
    • DOI 10.1086/514339
    • Kijpittayarit S, Eid AJ, Brown RA, Paya CV, Razonable RR. Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation. Clin Infect Dis 2007; 44: 1315-1320. (Pubitemid 46717293
    • (2007) Clinical Infectious Diseases , vol.44 , Issue.10 , pp. 1315-1320
    • Kijpittayarit, S.1    Eid, A.J.2    Brown, R.A.3    Paya, C.V.4    Razonable, R.R.5
  • 36
    • 0034891984 scopus 로고    scopus 로고
    • Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients
    • Kang TJ, Chae GT. Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients. FEMS Immunol Med Microbiol 2001; 31: 53-58
    • (2001) FEMS Immunol Med Microbiol , vol.31 , pp. 53-58
    • Kang, T.J.1    Chae, G.T.2
  • 37
    • 0036436470 scopus 로고    scopus 로고
    • A polymorphism in the toll-like receptor 2 is associated with IL-12 production from monocyte in lepromatous leprosy
    • DOI 10.1006/cyto.2002.1982
    • Kang TJ, Lee SB, Chae GT. A polymorphism in the toll-like receptor 2 is associated with IL-12 production from monocyte in lepromatous leprosy. Cytokine 2002; 20: 56-62. (Pubitemid 35373721
    • (2002) Cytokine , vol.20 , Issue.2 , pp. 56-62
    • Kang, T.J.1    Lee, S.-B.2    Chae, G.-T.3
  • 38
    • 4043156257 scopus 로고    scopus 로고
    • Differential production of interleukin-10 and interleukin-12 in mononuclear cells from leprosy patients with a Toll-like receptor 2 mutation
    • Kang TJ, Yeum CE, Kim BC, You EY, Chae GT. Differential production of interleukin-10 and interleukin-12 in mononuclear cells from leprosy patients with a Toll-like receptor 2 mutation. Immunology 2004; 112: 674-680
    • (2004) Immunology , vol.112 , pp. 674-680
    • Kang, T.J.1    Yeum, C.E.2    Kim, B.C.3    You, E.Y.4    Chae, G.T.5
  • 39
    • 2442714055 scopus 로고    scopus 로고
    • Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients
    • DOI 10.1128/CDLI.11.3.625-626.2004
    • Ben Ali M, Barbouche MR, Bousnina S, Chabbou A, Dellagi K. Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients. Clin Diagn Lab Immunol 2004; 11: 625-626. (Pubitemid 38661434
    • (2004) Clinical and Diagnostic Laboratory Immunology , vol.11 , Issue.3 , pp. 625-626
    • Ben-Ali, M.1    Barbouche, M.-R.2    Bousnina, S.3    Chabbou, A.4    Dellagi, K.5
  • 42
    • 34249983550 scopus 로고    scopus 로고
    • Tlr2 arg753gly, tlr4 asp299gly and thr399ile gene polymorphisms are not associated with chronic periodontitis in a turkish population
    • Berdeli A, Emingil G, Han Saygan B, Gurkan A, Atilla G, Köse T et al. TLR2 Arg753Gly, TLR4 Asp299Gly and Thr399Ile gene polymorphisms are not associated with chronic periodontitis in a Turkish population. J Clin Periodontol 2007; 34: 551-557
    • (2007) J Clin Periodontol , vol.34 , pp. 551-557
    • Berdeli, A.1    Emingil, G.2    Han Saygan, B.3    Gurkan, A.4    Atilla, G.5    Köse, T.6
  • 43
    • 34250744861 scopus 로고    scopus 로고
    • The lack of genetic association of the toll-like receptor 2 (tlr2) arg753gln and arg677trp polymorphisms with rheumatic heart disease
    • Düzgün N, Duman T, Haydardedeoǧlu FE, Tutkak H. The lack of genetic association of the Toll-like receptor 2 (TLR2) Arg753Gln and Arg677Trp polymorphisms with rheumatic heart disease. Clin Rheumatol 2007; 26: 915-919
    • (2007) Clin Rheumatol , vol.26 , pp. 915-919
    • Düzgün, N.1    Duman, T.2    Haydardedeoǧlu, F.E.3    Tutkak, H.4
  • 44
    • 33845894748 scopus 로고    scopus 로고
    • Lack of Toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia
    • Yoon HJ, Choi JY, Kim CO, Park YS, Kim MS, Kim YK et al. Lack of Toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia. J Korean Med Sci 2006; 21: 979-982
    • (2006) J Korean Med Sci , vol.21 , pp. 979-982
    • Yoon, H.J.1    Choi, J.Y.2    Kim, C.O.3    Park, Y.S.4    Kim, M.S.5    Kim, Y.K.6
  • 45
    • 1642521633 scopus 로고    scopus 로고
    • Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus
    • Sánchez E, Orozco G, Ló pez-Nevot MA, Jiménez-Alonso J, Martin J. Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus. Tissue Antigens 2004; 63: 54-57
    • (2004) Tissue Antigens , vol.63 , pp. 54-57
    • Sánchez, E.1    Orozco, G.2    López-Nevot, M.A.3    Jiménez-Alonso, J.4    Martin, J.5
  • 46
    • 10744224022 scopus 로고    scopus 로고
    • Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses
    • DOI 10.1128/IAI.72.3.1828-1831.2004
    • von Aulock S, Schröder NW, Traub S, Gueinzius K, Lorenz E, Hartung T et al. Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses. Infect Immun 2004; 72: 1828-1831. (Pubitemid 38263813
    • (2004) Infection and Immunity , vol.72 , Issue.3 , pp. 1828-1831
    • Von Aulock, S.1    Schroder, N.W.J.2    Traub, S.3    Gueinzius, K.4    Lorenz, E.5    Hartung, T.6    Schumann, R.R.7    Hermann, C.8
  • 47
    • 34447318082 scopus 로고    scopus 로고
    • Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene
    • DOI 10.1093/hmg/ddm070
    • Merx S, Neumaier M, Wagner H, Kirschning CJ, Ahmad-Nejad P. Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene. Hum Mol Genet 2007; 10: 1225-1232. (Pubitemid 47062718
    • (2007) Human Molecular Genetics , vol.16 , Issue.10 , pp. 1225-1232
    • Merx, S.1    Neumaier, M.2    Wagner, H.3    Kirschning, C.J.4    Ahmad-Nejad, P.5
  • 50
    • 84856573895 scopus 로고    scopus 로고
    • The association between Toll-like receptor 2 single-nucleotide polymorphism and hepatocellular carcinoma susceptibility
    • Junjie X, Songyao J, Minmin S, Yanyan S, Baiyong S, Xiaxing D et al. The association between Toll-like receptor 2 single-nucleotide polymorphism and hepatocellular carcinoma susceptibility. BMC Cancer 2012; 12: 57
    • (2012) BMC Cancer , vol.12 , pp. 57
    • Junjie, X.1    Songyao, J.2    Minmin, S.3    Yanyan, S.4    Baiyong, S.5    Xiaxing, D.6
  • 52
    • 83055163894 scopus 로고    scopus 로고
    • Genetic variants of Tolllike receptors 2 and 5, Helicobacter pylori infection, and risk of gastric cancer and its precursors in a Chinese population
    • Zeng HM, Pan KF, Zhang Y, Zhang L, Ma JL, Zhou T et al. Genetic variants of Tolllike receptors 2 and 5, Helicobacter pylori infection, and risk of gastric cancer and its precursors in a Chinese population. Cancer Epidemiol Biomarkers Prev 2011; 20: 2594-2602
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 2594-2602
    • Zeng, H.M.1    Pan, K.F.2    Zhang, Y.3    Zhang, L.4    Ma, J.L.5    Zhou, T.6
  • 55
    • 22644447473 scopus 로고    scopus 로고
    • Toll-like receptor 3 gene polymorphisms in South African blacks with type 1 diabetes
    • DOI 10.1111/j.1399-0039.2005.00454.x
    • Pirie FJ, Pegoraro R, Motala AA, Rauff S, Rom L, Govender T et al. Toll-like receptor 3 gene polymorphisms in South African blacks with type 1 diabetes. Tissue Antigens 2005; 66: 125-130. (Pubitemid 41025934
    • (2005) Tissue Antigens , vol.66 , Issue.2 , pp. 125-130
    • Pirie, F.J.1    Pegoraro, R.2    Motala, A.A.3    Rauff, S.4    Rom, L.5    Govender, T.6    Esterhuizen, T.M.7
  • 56
    • 79955531832 scopus 로고    scopus 로고
    • TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer
    • Castro FA, Försti A, Buch S, Kalthoff H, Krauss C, Bauer M et al. TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer 2011; 47: 1203-1210
    • (2011) Eur J Cancer , vol.47 , pp. 1203-1210
    • Castro, F.A.1    Försti, A.2    Buch, S.3    Kalthoff, H.4    Krauss, C.5    Bauer, M.6
  • 57
    • 80052453174 scopus 로고    scopus 로고
    • Evaluation of toll-like receptor 3 (c.1377C/T) and 9 (G2848A) gene polymorphism in cervical cancer susceptibility
    • Pandey S, Mittal B, Srivastava M, Singh S, Srivastava K, Lal P et al. Evaluation of Toll-like receptor 3 (c.1377C/T) and 9 (G2848A) gene polymorphism in cervical cancer susceptibility. Mol Biol Rep 2011; 38: 4715-4721
    • (2011) Mol Biol Rep , vol.38 , pp. 4715-4721
    • Pandey, S.1    Mittal, B.2    Srivastava, M.3    Singh, S.4    Srivastava, K.5    Lal, P.6
  • 58
    • 0033648133 scopus 로고    scopus 로고
    • Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4
    • research002.1-research002.10
    • Smirnova I, Poltorak A, Chan EK, McBride C, Beutler B. Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4). Genome Biol 2000; 1: Research002.1-research002.10
    • (2000) Genome Biol , vol.1
    • Smirnova, I.1    Poltorak, A.2    Chan, E.K.3    McBride, C.4    Beutler, B.5
  • 59
    • 0034858250 scopus 로고    scopus 로고
    • Excess of rare amino acid polymorphisms in the toll-like receptor 4 in humans
    • Smirnova I, Hamblin MT, McBride C, Beutler B, Di Rienzo A. Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans. Genetics 2001; 158: 1657-1664. (Pubitemid 32783146
    • (2001) Genetics , vol.158 , Issue.4 , pp. 1657-1664
    • Smirnova, I.1    Hamblin, M.T.2    McBride, C.3    Beutler, B.4    Rienzo, A.D.5
  • 62
    • 4444221545 scopus 로고    scopus 로고
    • A tlr4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12 (p70) responses in swedish children
    • Fageras Böttcher M, Hmani-Aifa M, Lindström A, Jenmalm MC, Mai XM, Nilsson L et al. A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children. J Allergy Clin Immunol 2004; 114: 561-567
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 561-567
    • Fageras Böttcher, M.1    Hmani-Aifa, M.2    Lindström, A.3    Jenmalm, M.C.4    Mai, X.M.5    Nilsson, L.6
  • 63
    • 8744301714 scopus 로고    scopus 로고
    • TLR4 and TNF-α polymorphisms are associated with an increased risk for severe sepsis following burn injury
    • DOI 10.1136/jmg.2004.021600
    • Barber RC, Aragaki CC, Rivera-Chavez FA, Purdue GF, Hunt JL, Horton JW. TLR4 and TNF-A polymorphisms are associated with an increased risk for severe sepsis following burn injury. J Med Genet 2004; 41: 808-813. (Pubitemid 39524306
    • (2004) Journal of Medical Genetics , vol.41 , Issue.11 , pp. 808-813
    • Barber, R.C.1    Aragaki, C.C.2    Rivera-Chavez, F.A.3    Purdue, G.F.4    Hunt, J.L.5    Horton, J.W.6
  • 64
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
    • Lorenz E, Mira JP, Frees KL, Schwartz DA. Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock. Arch Intern Med 2002; 162: 1028-1032. (Pubitemid 34492532
    • (2002) Archives of Internal Medicine , vol.162 , Issue.9 , pp. 1028-1032
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3    Schwartz, D.A.4
  • 65
    • 85047684648 scopus 로고    scopus 로고
    • Association between the Asp299Gly polymorphisms in the toll-like receptor 4 and premature births in the Finnish population
    • DOI 10.1203/01.PDR.0000025342.83436.53
    • Lorenz E, Hallman M, Marttila R, Haataja R, Schwartz DA. Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population. Pediatr Res 2002; 52: 373-376. (Pubitemid 34920267
    • (2002) Pediatric Research , vol.52 , Issue.3 , pp. 373-376
    • Lorenz, E.1    Hallman, M.2    Marttila, R.3    Haataja, R.4    Schwartz, D.A.5
  • 66
    • 35449000411 scopus 로고    scopus 로고
    • Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene?. Association study combined with meta-Analysis shows strong evidence for association
    • DOI 10.1111/j.1572-0241.2007.01463.x
    • Browning BL, Huebner C, Petermann I, Gearry RB, Barclay ML, Shelling AN et al. Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene?. Association study combined with meta-Analysis shows strong evidence for association. Am J Gastroenterol 2007; 102: 2504-2512. (Pubitemid 47631777
    • (2007) American Journal of Gastroenterology , vol.102 , Issue.11 , pp. 2504-2512
    • Browning, B.L.1    Huebner, C.2    Petermann, I.3    Gearry, R.B.4    Barclay, M.L.5    Shelling, A.N.6    Ferguson, L.R.7
  • 67
  • 69
    • 33645086385 scopus 로고    scopus 로고
    • The toll-like receptor 4 (asp299gly) polymorphism is a risk factor for gramnegative and haematogenous osteomyelitis
    • Montes AH, Asensi V, Alvarez V, Valle E, Ocan a MG, Meana A et al. The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gramnegative and haematogenous osteomyelitis. Clin Exp Immunol 2006; 143: 404-413
    • (2006) Clin Exp Immunol , vol.143 , pp. 404-413
    • Montes, A.H.1    Asensi, V.2    Alvarez, V.3    Valle, E.4    Ocan, A.M.G.5    Meana, A.6
  • 70
    • 33847225517 scopus 로고    scopus 로고
    • Heat shock protein 72 (HSPA1B) gene polymorphism and Toll-like receptor (TLR) 4 mutation are associated with increased risk of urinary tract infection in children
    • Karoly E, Fekete A, Banki NF, Szebeni B, Vannay A, Szabo AJ et al. Heat shock protein 72 (HSPA1B) gene polymorphism and Toll-like receptor (TLR) 4 mutation are associated with increased risk of urinary tract infection in children. Pediatr Res 2007; 61: 371-374
    • (2007) Pediatr Res , vol.61 , pp. 371-374
    • Karoly, E.1    Fekete, A.2    Banki, N.F.3    Szebeni, B.4    Vannay, A.5    Szabo, A.J.6
  • 72
    • 22044445110 scopus 로고    scopus 로고
    • Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-Associated lymphoid tissue lymphoma
    • Hellmig S, Fischbach W, Goebeler-Kolve ME, Fölsch UR, Hampe J, Schreiber S. Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-Associated lymphoid tissue lymphoma. Leuk Lymphoma 2005; 46: 869-872
    • (2005) Leuk Lymphoma , vol.46 , pp. 869-872
    • Hellmig, S.1    Fischbach, W.2    Goebeler-Kolve, M.E.3    Fölsch, U.R.4    Hampe, J.5    Schreiber, S.6
  • 73
    • 33847063192 scopus 로고    scopus 로고
    • Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis
    • Hofner P, Gyulai Z, Kiss ZF, Tiszai A, Tiszlavicz L, Tó th G et al. Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis. Helicobacter 2007; 12: 124-131
    • (2007) Helicobacter , vol.12 , pp. 124-131
    • Hofner, P.1    Gyulai, Z.2    Kiss, Z.F.3    Tiszai, A.4    Tiszlavicz, L.5    Tóth, G.6
  • 75
    • 53749088030 scopus 로고    scopus 로고
    • Tlr4 single-nucleotide polymorphisms alter mucosal cytokine and chemokine patterns in Mexican patients with Helicobacter pyloriassociated gastroduodenal diseases
    • Trejo-de la OA, Torres J, Pé rez-Rodríguez M, Camorlinga-Ponce M, Luna LF, Abdo-Francis JM et al. TLR4 single-nucleotide polymorphisms alter mucosal cytokine and chemokine patterns in Mexican patients with Helicobacter pyloriassociated gastroduodenal diseases. Clin Immunol 2008; 129: 333-340
    • (2008) Clin Immunol , vol.129 , pp. 333-340
    • Trejo-De La, O.A.1    Torres, J.2    Pérez-Rodríguez, M.3    Camorlinga-Ponce, M.4    Luna, L.F.5    Abdo-Francis, J.M.6
  • 79
    • 28444494743 scopus 로고    scopus 로고
    • Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease
    • DOI 10.1016/j.neulet.2005.08.047, PII S0304394005009924
    • Minoretti P, Gazzaruso C, Vito CD, Emanuele E, Bianchi M, Coen E et al. Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease. Neurosci Lett 2006; 391: 147-149. (Pubitemid 41736189
    • (2006) Neuroscience Letters , vol.391 , Issue.3 , pp. 147-149
    • Minoretti, P.1    Gazzaruso, C.2    Vito, C.D.3    Emanuele, E.4    Bianchi, M.5    Coen, E.6    Reino, M.7    Geroldi, D.8
  • 81
    • 33847649589 scopus 로고    scopus 로고
    • Polymorphism in the IL-8 gene, but not in the TLR4 gene, increases the severity of acute pancreatitis
    • DOI 10.1159/000097363
    • Hofner P, Balog A, Gyulai Z, Farkas G, Rakonczay Z, Takács T et al. Polymorphism in the IL-8 gene, but not in the TLR4 gene, increases the severity of acute pancreatitis. Pancreatology 2006; 6: 542-548. (Pubitemid 46360712
    • (2006) Pancreatology , vol.6 , Issue.6 , pp. 542-548
    • Hofner, P.1    Balog, A.2    Gyulai, Z.3    Farkas, G.4    Rakonczay, Z.5    Takacs, T.6    Mandi, Y.7
  • 83
    • 41849124921 scopus 로고    scopus 로고
    • Analysis of single nucleotide polymorphisms in Toll-like receptor 4 shows no association with ankylosing spondylitis in a Korean population
    • Na KS, Kim TH, Rahman P, Peddle L, Choi CB, Inman RD. Analysis of single nucleotide polymorphisms in Toll-like receptor 4 shows no association with ankylosing spondylitis in a Korean population. Rheumatol Int 2008; 28: 627-630
    • (2008) Rheumatol Int , vol.28 , pp. 627-630
    • Na, K.S.1    Kim, T.H.2    Rahman, P.3    Peddle, L.4    Choi, C.B.5    Inman, R.D.6
  • 84
    • 29244441698 scopus 로고    scopus 로고
    • Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer
    • DOI 10.1158/0008-5472.CAN-05-2078
    • Chen YC, Giovannucci E, Lazarus R, Kraft P, Ketkar S, Hunter DJ. Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer. Cancer Res 2005; 65: 11771-11778. (Pubitemid 41821739
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11771-11778
    • Chen, Y.-C.1    Giovannucci, E.2    Lazarus, R.3    Kraft, P.4    Ketkar, S.5    Hunter, D.J.6
  • 85
    • 34547692610 scopus 로고    scopus 로고
    • Functional significance of the TLR4/11367 polymorphism identified in Chinese Han population
    • DOI 10.1097/SHK.0b013e31803df782, PII 0002438220070800000006
    • Duan ZX, Zhu PF, Dong H, Gu W, Yang C, Liu Q et al. Functional significance of the TLR4/11367 polymorphism identified in Chinese Han population. Shock 2007; 28: 160-164. (Pubitemid 47220826
    • (2007) Shock , vol.28 , Issue.2 , pp. 160-164
    • Duan, Z.-X.1    Zhu, P.-F.2    Dong, H.3    Gu, W.4    Yang, C.5    Liu, Q.6    Wang, Z.-G.7    Jiang, J.-X.8
  • 86
    • 49249127841 scopus 로고    scopus 로고
    • Molecular interactions between Dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies
    • Apetoh L, Tesniere A, Ghiringhelli F, Kroemer G, Zitvogel L. Molecular interactions between Dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies. Cancer Res 2008; 68: 4026-4030
    • (2008) Cancer Res , vol.68 , pp. 4026-4030
    • Apetoh, L.1    Tesniere, A.2    Ghiringhelli, F.3    Kroemer, G.4    Zitvogel, L.5
  • 95
    • 35349027410 scopus 로고    scopus 로고
    • Genetic polymorphisms of viral infection-Associated Toll-like receptors in Chinese population
    • Cheng PL, Eng HL, Chou MH, You HL, Lin TM. Genetic polymorphisms of viral infection-Associated Toll-like receptors in Chinese population. Transl Res 2007; 150: 311-318
    • (2007) Transl Res , vol.150 , pp. 311-318
    • Cheng, P.L.1    Eng, H.L.2    Chou, M.H.3    You, H.L.4    Lin, T.M.5
  • 97
    • 0037289001 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three US ethnic groups and exploratory case-control disease association studies
    • DOI 10.1016/S0888-7543(02)00022-8
    • Lazarus R, Klimecki WT, Raby BA, Vercelli D, Palmer LJ, Kwiatkowski DJ et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003; 81: 85-91. (Pubitemid 36263362
    • (2003) Genomics , vol.81 , Issue.1 , pp. 85-91
    • Lazarus, R.1    Klimecki, W.T.2    Raby, B.A.3    Vercelli, D.4    Palmer, L.J.5    Kwiatkowski, D.J.6    Silverman, E.K.7    Martinez, F.8    Weiss, S.T.9
  • 100
    • 27744509806 scopus 로고    scopus 로고
    • Polymorphisms of the toll-like receptor 9 (TLR9) gene with systemic lupus erythematosus in Chinese [1
    • DOI 10.1093/rheumatology/kei120
    • Ng MW, Lau CS, Chan TM, Wong WH, Lau YL. Polymorphisms of the toll-like receptor 9 (TLR9) gene with systemic lupus erythematosus in Chinese. Rheumatology (Oxford) 2005; 44: 1456-1457. (Pubitemid 41631873
    • (2005) Rheumatology , vol.44 , Issue.11 , pp. 1456-1457
    • Ng, M.W.1    Lau, C.S.2    Chan, T.M.3    Wong, W.H.S.4    Lau, Y.L.5
  • 101
    • 33646340664 scopus 로고    scopus 로고
    • Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus
    • DOI 10.1002/art.21755
    • De Jager PL, Richardson A, Vyse TJ, Rioux JD. Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum 2006; 54: 1279-1282. (Pubitemid 43672940
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.4 , pp. 1279-1282
    • De Jager, P.L.1    Richardson, A.2    Vyse, T.J.3    Rioux, J.D.4
  • 102
    • 33644811344 scopus 로고    scopus 로고
    • Common human Toll-like receptor 9 polymorphisms and haplotypes: Association with atopy and functional relevance
    • Berghöfer B, Frommer T, König IR, Ziegler A, Chakraborty T, Bein G et al. Common human Toll-like receptor 9 polymorphisms and haplotypes: Association with atopy and functional relevance. Clin Exp Allergy 2005; 35: 1147-1154
    • (2005) Clin Exp Allergy , vol.35 , pp. 1147-1154
    • Berghöfer, B.1    Frommer, T.2    König, I.R.3    Ziegler, A.4    Chakraborty, T.5    Bein, G.6
  • 103
    • 1542285261 scopus 로고    scopus 로고
    • An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population
    • DOI 10.1111/j.1365-2222.2004.01839.x
    • Noguchi E, Nishimura F, Fukai H, Kim J, Ichikawa K, Shibasaki M et al. An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population. Clin Exp Allergy 2004; 34: 177-183. (Pubitemid 38315251
    • (2004) Clinical and Experimental Allergy , vol.34 , Issue.2 , pp. 177-183
    • Noguchi, E.1    Nishimura, F.2    Fukai, H.3    Kim, J.4    Ichikawa, K.5    Shibasaki, M.6    Arinami, T.7
  • 106
    • 33847021903 scopus 로고    scopus 로고
    • Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection
    • Bochud PY, Hersberger M, Taffé P, Bochud M, Stein CM, Rodrigues SD et al. Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection. AIDS 2007; 21: 441-446
    • (2007) AIDS , vol.21 , pp. 441-446
    • Bochud, P.Y.1    Hersberger, M.2    Taffé, P.3    Bochud, M.4    Stein, C.M.5    Rodrigues, S.D.6
  • 107
    • 77954680620 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) and nucleosome-binding oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk
    • Ashton KA, Proietto A, Otton G, Symonds I, McEvoy M, Attia J et al. Toll-like receptor (TLR) and nucleosome-binding oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk. BMC Cancer 2010; 10: 382
    • (2010) BMC Cancer , vol.10 , pp. 382
    • Ashton, K.A.1    Proietto, A.2    Otton, G.3    Symonds, I.4    McEvoy, M.5    Attia, J.6
  • 109
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511. (Pubitemid 38931765
    • (2004) Nature Reviews Immunology , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 113
    • 84859108570 scopus 로고    scopus 로고
    • Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population
    • Morgan AR, Lam WJ, Han DY, Fraser AG, Ferguson LR. Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population. Hum Immunol 2012; 73: 416-420
    • (2012) Hum Immunol , vol.73 , pp. 416-420
    • Morgan, A.R.1    Lam, W.J.2    Han, D.Y.3    Fraser, A.G.4    Ferguson, L.R.5
  • 114
    • 84872352748 scopus 로고    scopus 로고
    • A missense polymorphism (rs11466653, Met326Thr) of toll-like receptor 10 (TLR10) is associated with tumor size of papillary thyroid carcinoma in the Korean population
    • Kim SK, Park HJ, Hong IK, Chung JH, Eun YG. A missense polymorphism (rs11466653, Met326Thr) of toll-like receptor 10 (TLR10) is associated with tumor size of papillary thyroid carcinoma in the Korean population. Endocrine 2013; 43: 161-169.
    • (2013) Endocrine , vol.43 , pp. 161-169
    • Kim, S.K.1    Park, H.J.2    Hong, I.K.3    Chung, J.H.4    Eun, Y.G.5


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