-
1
-
-
0030831210
-
A human homologue of the Drosophila toll protein signals activation of adaptive immunity
-
Medzhitov, R., Preston-Hurlburt, P. and Janeway, C.A., Jr. (1997) A human homologue of the Drosophila toll protein signals activation of adaptive immunity. Nature, 388, 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., He, X., Smirnova, I., Liu, M.Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C. et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science, 282, 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
3
-
-
0012929728
-
Toll-like receptors
-
Takeda, K., Kaisho, T. and Akira, S. (2002) Toll-like receptors. Annu. Rev. Immunol., 21, 335-376.
-
(2002)
Annu. Rev. Immunol
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
4
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang, D., Zhang, G., Hayden, M.S., Greenblatt, M.B., Bussey, C., Flavell, R.A. and Ghosh, S. (2004) A toll-like receptor that prevents infection by uropathogenic bacteria. Science, 303, 1522-1526.
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
5
-
-
0038664380
-
The role of toll-like receptor 2 in microbial disease and immunity
-
Wetzler, L.M. (2003) The role of toll-like receptor 2 in microbial disease and immunity. Vaccine, 21, 55-60.
-
(2003)
Vaccine
, vol.21
, pp. 55-60
-
-
Wetzler, L.M.1
-
6
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky, A., Underhill, D.M., Fontenot, J.D., Hajjar, A.M., Smith, K.D., Wilson, C.B., Schroeder, L. and Aderem, A. (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. USA, 97, 13766-13771.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
7
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda, K. and Akira, S. (2005) Toll-like receptors in innate immunity. Int. Immunol., 17, 1-14.
-
(2005)
Int. Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
8
-
-
10744226016
-
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease
-
Hawn, T.R., Verbon, A., Lettinga, K.D., Zhao, L.P., Li, S.S., Laws, R.J., Skerrett, S.J., Beutler, B., Schroeder, L., Nachman, A. et al. (2003) A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease. J. Exp. Med., 198, 1563-1572.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
-
9
-
-
0141786370
-
Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings
-
Michel, O., LeVan, T.D., Stern, D., Dentener, M., Thorn, J., Gnat, D., Beijer, M.L., Cochaux, P., Holt, P.G., Martinez, F.D. and Rylander, R. (2003) Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings. J. Allergy Clin. Immunol., 112, 923-929.
-
(2003)
J. Allergy Clin. Immunol
, vol.112
, pp. 923-929
-
-
Michel, O.1
LeVan, T.D.2
Stern, D.3
Dentener, M.4
Thorn, J.5
Gnat, D.6
Beijer, M.L.7
Cochaux, P.8
Holt, P.G.9
Martinez, F.D.10
Rylander, R.11
-
10
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
Franchimont, D., Vermeire, S., El Housni, H., Pierik, M., Van Steen, K., Gustot, T., Quertinmont, E., Abramowicz, M., Van Gossum, A., Deviere, J. et al. (2004) Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut, 53 987-992.
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
Pierik, M.4
Van Steen, K.5
Gustot, T.6
Quertinmont, E.7
Abramowicz, M.8
Van Gossum, A.9
Deviere, J.10
-
11
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
Lorenz, E., Mira, J.P., Frees, K.L. and Schwartz, D.A. (2002) Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch. Intern. Med., 162, 1028-1032.
-
(2002)
Arch. Intern. Med
, vol.162
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
12
-
-
1042269515
-
The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease
-
Ogus, A.C., Yoldas, B., Ozdemir, T., Uguz, A., Olcen, S., Keser, I., Coskun, M., Cilli, A. and Yegin, O. (2004) The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. Eur. Respir. J., 23, 219-223.
-
(2004)
Eur. Respir. J
, vol.23
, pp. 219-223
-
-
Ogus, A.C.1
Yoldas, B.2
Ozdemir, T.3
Uguz, A.4
Olcen, S.5
Keser, I.6
Coskun, M.7
Cilli, A.8
Yegin, O.9
-
13
-
-
23744442371
-
TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children
-
Berdeli, A., Celik, H.A., Ozyurek, R., Dogrusoz, B. and Aydin, H.H. (2005) TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children. J. Mol. Med., 83, 535-541.
-
(2005)
J. Mol. Med
, vol.83
, pp. 535-541
-
-
Berdeli, A.1
Celik, H.A.2
Ozyurek, R.3
Dogrusoz, B.4
Aydin, H.H.5
-
14
-
-
0033794461
-
A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection
-
Lorenz, E., Mira, J.P., Cornish, K.L., Arbour, N.C. and Schwartz, D.A. (2000) A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect. Immun. 68, 6398-6401.
-
(2000)
Infect. Immun
, vol.68
, pp. 6398-6401
-
-
Lorenz, E.1
Mira, J.P.2
Cornish, K.L.3
Arbour, N.C.4
Schwartz, D.A.5
-
15
-
-
21544462582
-
A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis
-
Hamann, L., Gomma, A., Schroder, N.W., Stamme, C., Glaeser, C., Schulz, S., Gross, M., Anker, S.D., Fox, K. and Schumann, R.R. (2005) A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis. J. Mol. Med., 83, 478-485.
-
(2005)
J. Mol. Med
, vol.83
, pp. 478-485
-
-
Hamann, L.1
Gomma, A.2
Schroder, N.W.3
Stamme, C.4
Glaeser, C.5
Schulz, S.6
Gross, M.7
Anker, S.D.8
Fox, K.9
Schumann, R.R.10
-
16
-
-
23444453397
-
Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease
-
Schroder, N.W., Diterich, I., Zinke, A., Eckert, J., Draing, C., von Baehr, V., Hassler, D., Priem, S., Hahn, K., Michelsen, K.S. et al. (2005) Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease. J. Immunol., 175, 2534-2540.
-
(2005)
J. Immunol
, vol.175
, pp. 2534-2540
-
-
Schroder, N.W.1
Diterich, I.2
Zinke, A.3
Eckert, J.4
Draing, C.5
von Baehr, V.6
Hassler, D.7
Priem, S.8
Hahn, K.9
Michelsen, K.S.10
-
17
-
-
0034891984
-
Detection of toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients
-
Kang, T.J. and Chae, G.T. (2001) Detection of toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients. FEMS Immunol. Med. Microbiol., 31, 53-58.
-
(2001)
FEMS Immunol. Med. Microbiol
, vol.31
, pp. 53-58
-
-
Kang, T.J.1
Chae, G.T.2
-
18
-
-
17144400786
-
TLR2 Arg677Trp polymorphism in leprosy: Revisited
-
Malhotra, D., Relhan, V., Reddy, B.S. and Bamezai, R. (2005) TLR2 Arg677Trp polymorphism in leprosy: Revisited. Hum. Genet., 116 413-415.
-
(2005)
Hum. Genet
, vol.116
, pp. 413-415
-
-
Malhotra, D.1
Relhan, V.2
Reddy, B.S.3
Bamezai, R.4
-
19
-
-
33745022091
-
Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2
-
Kataoka, H., Yasuda, M., Iyori, M., Kiura, K., Narita, M., Nakata, T. and Shibata, K. (2006) Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2. Cell. Microbiol., 8, 1199-1209.
-
(2006)
Cell. Microbiol
, vol.8
, pp. 1199-1209
-
-
Kataoka, H.1
Yasuda, M.2
Iyori, M.3
Kiura, K.4
Narita, M.5
Nakata, T.6
Shibata, K.7
-
20
-
-
9144233004
-
Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides
-
Grabiec, A., Meng, G., Fichte, S., Bessler, W., Wagner, H. and Kirschning, C.J. (2004) Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides. J. Biol. Chem., 279, 48004-48012.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 48004-48012
-
-
Grabiec, A.1
Meng, G.2
Fichte, S.3
Bessler, W.4
Wagner, H.5
Kirschning, C.J.6
-
21
-
-
0038466165
-
High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR
-
Schroeder, N.W., Hermann, C., Hamann, L., Gobel, U.B., Hartung, T. and Schumann, R.R. (2003) High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR. J. Mol. Med., 81, 368-372.
-
(2003)
J. Mol. Med
, vol.81
, pp. 368-372
-
-
Schroeder, N.W.1
Hermann, C.2
Hamann, L.3
Gobel, U.B.4
Hartung, T.5
Schumann, R.R.6
-
22
-
-
0141559415
-
Leucine-rich repeats and pathogen recognition in Toll-like receptors
-
Bell, J.K., Mullen, G.E., Leifer, C.A., Mazzoni, A., Davies, D.R. and Segal, D.M. (2003) Leucine-rich repeats and pathogen recognition in Toll-like receptors. Trends. Immunol., 24, 528-533.
-
(2003)
Trends. Immunol
, vol.24
, pp. 528-533
-
-
Bell, J.K.1
Mullen, G.E.2
Leifer, C.A.3
Mazzoni, A.4
Davies, D.R.5
Segal, D.M.6
-
23
-
-
0141994786
-
Cellular recognition of tri-/ di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2
-
Meng, G., Grabiec, A., Vallon, M., Ebe, B., Hampel, S., Bessler, W., Wagner, H. and Kirschning, C.J. (2003) Cellular recognition of tri-/ di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2. J. Biol. Chem., 278, 39822-39829.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 39822-39829
-
-
Meng, G.1
Grabiec, A.2
Vallon, M.3
Ebe, B.4
Hampel, S.5
Bessler, W.6
Wagner, H.7
Kirschning, C.J.8
-
24
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by toll-like receptor 5
-
Hayashi, F., Smith, K.D., Ozinsky, A., Hawn, T.R., Yi, E.C., Goodlett, D.R., Eng, J.K., Akira, S., Underhill, D.M. and Aderem, A. (2001) The innate immune response to bacterial flagellin is mediated by toll-like receptor 5. Nature, 410, 1099-1103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
25
-
-
1542721096
-
The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype
-
Ahmad-Nejad, P., Mrabet-Dahbi, S., Breuer, K., Klotz, M., Werfel, T., Herz, U., Heeg, K., Neumaier, M. and Renz, H. (2004) The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype. J. Allergy Clin. Immunol., 113, 565-567.
-
(2004)
J. Allergy Clin. Immunol
, vol.113
, pp. 565-567
-
-
Ahmad-Nejad, P.1
Mrabet-Dahbi, S.2
Breuer, K.3
Klotz, M.4
Werfel, T.5
Herz, U.6
Heeg, K.7
Neumaier, M.8
Renz, H.9
-
26
-
-
33745346806
-
Lack of association between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema
-
Weidinger, S., Novak, N., Klopp, N., Baurecht, H., Wagenpfeil, S., Rummler, L., Ring, J., Behrendt, H. and Illig, T. (2006) Lack of association between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema. J. Allergy Clin. Immunol., 118 277-279.
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 277-279
-
-
Weidinger, S.1
Novak, N.2
Klopp, N.3
Baurecht, H.4
Wagenpfeil, S.5
Rummler, L.6
Ring, J.7
Behrendt, H.8
Illig, T.9
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