Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Ashton, Katie A ^a   Proietto, Anthony ^a,b   Otton, Geoffrey ^a,b   Symonds, Ian ^a   McEvoy, Mark ^a   Attia, John ^a   Scott, Rodney J ^a,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b JOHN HUNTER HOSPITAL   (Australia)

^c JOHN HUNTER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; NOD1 PROTEIN, HUMAN; NOD2 PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; AUSTRALIA; CANCER RISK; CONTROLLED STUDY; ENDOMETRIUM CANCER; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POPULATION RISK; REAL TIME POLYMERASE CHAIN REACTION; CASE CONTROL STUDY; COMPARATIVE STUDY; ENDOMETRIUM TUMOR; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; MIDDLE AGED; PATHOLOGY; PROGNOSIS; RISK FACTOR; SURVIVAL RATE;

AGED; AUSTRALIA; CASE-CONTROL STUDIES; ENDOMETRIAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, GENETIC; PROGNOSIS; RISK FACTORS; SURVIVAL RATE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9;

EID: 77954680620     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-382     Document Type: Article

References (23)

1. AIHW Australian Institute of Health and Welfare, Cancer in Australia: an overview, 2006. Cancer Series no. 37 2007, AIHW., http://www.aihw.gov.au/publications/index.cfm/title/10476
2. Akhmedkhanov A, Zeleniuch-Jacquotte A, Toniolo P. Role of exogenous and endogenous hormones in endometrial cancer: review of the evidence and research perspectives. Annals of the New York Academy of Sciences 2001, 943:296-315. 10.1111/j.1749-6632.2001.tb03811.x, 11594550.
3. Bray F, Loos AH, Oostindier M, Weiderpass E. Geographic and temporal variations in cancer of the corpus uteri: incidence and mortality in pre- and postmenopausal women in Europe. International journal of cancer 2005, 117(1):123-131.
4. Doll A, Abal M, Rigau M, Monge M, Gonzalez M, Demajo S, Colas E, Llaurado M, Alazzouzi H, Planaguma J, et al. Novel molecular profiles of endometrial cancer-new light through old windows. The Journal of steroid biochemistry and molecular biology 2008, 108(3-5):221-229. 10.1016/j.jsbmb.2007.09.020, 18061438.
5. Modugno F, Ness RB, Chen C, Weiss NS. Inflammation and endometrial cancer: a hypothesis. Cancer Epidemiol Biomarkers Prev 2005, 14(12):2840-2847. 10.1158/1055-9965.EPI-05-0493, 16364998.
6. Allhorn S, Boing C, Koch AA, Kimmig R, Gashaw I. TLR3 and TLR4 expression in healthy and diseased human endometrium. Reprod Biol Endocrinol 2008, 6:40. 10.1186/1477-7827-6-40, 2543020, 18775079.
7. Weiss G, Goldsmith LT, Taylor RN, Bellet D, Taylor HS. Inflammation in reproductive disorders. Reprod Sci 2009, 16(2):216-229. 10.1177/1933719108330087, 19208790.
8. Grivennikov SI, Karin M. Inflammation and oncogenesis: a vicious connection. Curr Opin Genet Dev 2009, Epub: 2009/12/29.
9. Medzhitov R, Janeway CA. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997, 91(3):295-298. 10.1016/S0092-8674(00)80412-2, 9363937.
10. Ospelt C, Gay S. TLRs and chronic inflammation. Int J Biochem Cell Biol 2009,
11. Carneiro LA, Magalhaes JG, Tattoli I, Philpott DJ, Travassos LH. Nod-like proteins in inflammation and disease. The Journal of pathology 2008, 214(2):136-148. 10.1002/path.2271, 18161746.
12. El-Omar EM, Ng MT, Hold GL. Polymorphisms in Toll-like receptor genes and risk of cancer. Oncogene 2008, 27(2):244-252. 10.1038/sj.onc.1210912, 18176606.
13. Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000, 408(6813):740-745. 10.1038/35047123, 11130078.
14. Pasare C, Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv Exp Med Biol 2005, 560:11-18. full_text, 15932016.
15. Ashton KA, Proietto A, Otton G, Symonds I, McEvoy M, Attia J, Gilbert M, Hamann U, Scott RJ. The influence of the Cyclin D1 870 G > A polymorphism as an endometrial cancer risk factor. BMC Cancer 2008, 8:272. 10.1186/1471-2407-8-272, 2567988, 18822177.
16. Ashton KA, Proietto A, Otton G, Symonds I, McEvoy M, Attia J, Gilbert M, Hamann U, Scott RJ. Estrogen receptor polymorphisms and the risk of endometrial cancer. BJOG 2009, 116(8):1053-1061.
17. Ashton KA, Proietto A, Otton G, Symonds I, McEvoy M, Attia J, Gilbert M, Hamann U, Scott RJ. Polymorphisms in TP53 and MDM2 combined are associated with high grade endometrial cancer. Gynecologic oncology 2009, 113(1):109-114. 10.1016/j.ygyno.2008.12.036, 19193430.
18. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic acids research 1988, 16(3):1215. 10.1093/nar/16.3.1215, 334765, 3344216.
19. Carter KW, McCaskie PA, Palmer LJ. SimHap GUI: An intuitive graphical user interface for genetic association analysis. BMC Bioinformatics 2008, 25, 9(1):557.
20. Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002, 20:709-760. 10.1146/annurev.immunol.20.100301.064842, 11861616.
21. Novak N, Yu CF, Bussmann C, Maintz L, Peng WM, Hart J, Hagemann T, Diaz-Lacava A, Baurecht HJ, Klopp N, et al. Putative association of a TLR9 promoter polymorphism with atopic eczema. Allergy 2007, 62(7):766-772. 10.1111/j.1398-9995.2007.01358.x, 17573724.
22. Ng MT, van't Hof R, Crockett JC, Hope ME, Berry S, Thomson J, McLean MH, McColl KE, El-Omar EM, Hold GL. Increase in NF-{kappa}B binding affinity of the C allelic variant of the Toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori induced gastric disease. Infect Immun 2009, Epub: 2009/12/30.
23. Lazarus R, Klimecki WT, Raby BA, Vercelli D, Palmer LJ, Kwiatkowski DJ, Silverman EK, Martinez F, Weiss ST. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003, 81(1):85-91. 10.1016/S0888-7543(02)00022-8, 12573264.