-
1
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001 1 : 135 45.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 135-45
-
-
Medzhitov, R.1
-
2
-
-
0031050034
-
Innate immunity: Impact on the adaptive immune response
-
Medzhitov R, Janeway CA Jr. Innate immunity: Impact on the adaptive immune response. Curr Opin Immunol 1997 9 : 4 9.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 4-9
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
3
-
-
0038242875
-
Toll-like receptor signaling pathways
-
Barton GM, Medzhitov R. Toll-like receptor signaling pathways. Science 2003 300 : 1524 5.
-
(2003)
Science
, vol.300
, pp. 1524-5
-
-
Barton, G.M.1
Medzhitov, R.2
-
4
-
-
1842455329
-
Genetics of inflammatory bowel disease: Progress and prospects
-
Mathew CG, Lewis CM. Genetics of inflammatory bowel disease: Progress and prospects. Hum Mol Genet 2004 13 : R161 8.
-
(2004)
Hum Mol Genet
, vol.13
-
-
Mathew, C.G.1
Lewis, C.M.2
-
5
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? the toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
Franchimont D, Vermeire S, El Housni H, et al. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 2004 53 : 987 92.
-
(2004)
Gut
, vol.53
, pp. 987-92
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
-
6
-
-
4344671141
-
NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: Evidence for genetic heterogeneity within Europe?
-
Arnott ID, Nimmo ER, Drummond HE, et al. NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: Evidence for genetic heterogeneity within Europe? Genes Immun 2004 5 : 417 25.
-
(2004)
Genes Immun
, vol.5
, pp. 417-25
-
-
Arnott, I.D.1
Nimmo, E.R.2
Drummond, H.E.3
-
7
-
-
23844495249
-
Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients
-
Braat H, Stokkers P, Hommes T, et al. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients. J Mol Med 2005 83 : 601 9.
-
(2005)
J Mol Med
, vol.83
, pp. 601-9
-
-
Braat, H.1
Stokkers, P.2
Hommes, T.3
-
8
-
-
20444467612
-
Association between Toll-like receptor 4 and inflammatory bowel disease
-
Oostenbrug LE, Drenth JP, de Jong DJ, et al. Association between Toll-like receptor 4 and inflammatory bowel disease. Inflamm Bowel Dis 2005 11 : 567 75.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 567-75
-
-
Oostenbrug, L.E.1
Drenth, J.P.2
De Jong, D.J.3
-
9
-
-
14544281031
-
The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway
-
Ouburg S, Mallant-Hent R, Crusius JB, et al. The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway. Gut 2005 54 : 439 40.
-
(2005)
Gut
, vol.54
, pp. 439-40
-
-
Ouburg, S.1
Mallant-Hent, R.2
Crusius, J.B.3
-
10
-
-
13544276471
-
Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population
-
Gazouli M, Mantzaris G, Kotsinas A, et al. Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol 2005 11 : 681 5.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 681-5
-
-
Gazouli, M.1
Mantzaris, G.2
Kotsinas, A.3
-
11
-
-
22044432709
-
The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease
-
Brand S, Staudinger T, Schnitzler F, et al. The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease. Inflamm Bowel Dis 2005 11 : 645 52.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 645-52
-
-
Brand, S.1
Staudinger, T.2
Schnitzler, F.3
-
12
-
-
20144387613
-
Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations
-
Lakatos PL, Lakatos L, Szalay F, et al. Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations. World J Gastroenterol 2005 11 : 1489 95.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1489-95
-
-
Lakatos, P.L.1
Lakatos, L.2
Szalay, F.3
-
13
-
-
2942689466
-
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: Association of a mutation in the toll-like receptor 4 gene with ulcerative colitis
-
Torok HP, Glas J, Tonenchi L, et al. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: Association of a mutation in the toll-like receptor 4 gene with ulcerative colitis. Clin Immunol 2004 112 : 85 91.
-
(2004)
Clin Immunol
, vol.112
, pp. 85-91
-
-
Torok, H.P.1
Glas, J.2
Tonenchi, L.3
-
14
-
-
33846175696
-
The prevalence of genetic and serologic markers in an unselected European population-based cohort of IBD patients
-
Riis L, Vind I, Vermeire S, et al. The prevalence of genetic and serologic markers in an unselected European population-based cohort of IBD patients. Inflamm Bowel Dis 2007 13 : 24 32.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 24-32
-
-
Riis, L.1
Vind, I.2
Vermeire, S.3
-
15
-
-
33644827003
-
Intestinal permeability and genetic determinants in patients, first-degree relatives, and controls in a high-incidence area of Crohn's disease in Southern Italy
-
Fries W, Renda MC, Lo Presti MA, et al. Intestinal permeability and genetic determinants in patients, first-degree relatives, and controls in a high-incidence area of Crohn's disease in Southern Italy. Am J Gastroenterol 2005 100 : 2730 6.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2730-6
-
-
Fries, W.1
Renda, M.C.2
Lo Presti, M.A.3
-
16
-
-
33645105960
-
Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort
-
Tremelling M, Waller S, Bredin F, et al. Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort. Inflamm Bowel Dis 2006 12 : 178 84.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 178-84
-
-
Tremelling, M.1
Waller, S.2
Bredin, F.3
-
17
-
-
33847366601
-
Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population
-
Pearce AV, Fisher SA, Prescott NJ, et al. Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population. Int J Colorectal Dis 2007 22 : 419 24.
-
(2007)
Int J Colorectal Dis
, vol.22
, pp. 419-24
-
-
Pearce, A.V.1
Fisher, S.A.2
Prescott, N.J.3
-
18
-
-
33845622964
-
Genetic variation in myosin IXB is associated with ulcerative colitis
-
Van Bodegraven AA, Curley CR, Hunt KA, et al. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 2006 131 : 1768 74.
-
(2006)
Gastroenterology
, vol.131
, pp. 1768-74
-
-
Van Bodegraven, A.A.1
Curley, C.R.2
Hunt, K.A.3
-
19
-
-
33744482013
-
Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19
-
Tello-Ruiz MK, Curley C, DelMonte T, et al. Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19. Eur J Hum Genet 2006 14 : 780 90.
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 780-90
-
-
Tello-Ruiz, M.K.1
Curley, C.2
Delmonte, T.3
-
20
-
-
0031793132
-
The significance of haemochromatosis gene mutations in the general population: Implications for screening
-
Burt MJ, George PM, Upton JD, et al. The significance of haemochromatosis gene mutations in the general population: Implications for screening. Gut 1998 43 : 830 6.
-
(1998)
Gut
, vol.43
, pp. 830-6
-
-
Burt, M.J.1
George, P.M.2
Upton, J.D.3
-
21
-
-
33749316892
-
High incidence of Crohn's disease in Canterbury, New Zealand: Results of an epidemiologic study
-
Gearry RB, Richardson A, Frampton CM, et al. High incidence of Crohn's disease in Canterbury, New Zealand: Results of an epidemiologic study. Inflamm Bowel Dis 2006 12 : 936 43.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 936-43
-
-
Gearry, R.B.1
Richardson, A.2
Frampton, C.M.3
-
22
-
-
0024810567
-
Classification of inflammatory bowel disease
-
discussion 16-9.
-
Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol Suppl 1989 170 : 2 6 discussion 16-9.
-
(1989)
Scand J Gastroenterol Suppl
, vol.170
, pp. 2-6
-
-
Lennard-Jones, J.E.1
-
23
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005 19 (Suppl A 5 36.
-
(2005)
Can J Gastroenterol
, vol.19
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
24
-
-
0034436178
-
Automated mass spectrometry: A revolutionary technology for clinical diagnostics
-
Leushner J, Chiu NH. Automated mass spectrometry: A revolutionary technology for clinical diagnostics. Mol Diagn 2000 5 : 341 8.
-
(2000)
Mol Diagn
, vol.5
, pp. 341-8
-
-
Leushner, J.1
Chiu, N.H.2
-
25
-
-
35448946994
-
-
R Development Core Team. R: A Language and Environment for Statistical Computing Vienna, Austria: R Foundation for Statistical Computing
-
R Development Core Team. R: A Language and Environment for Statistical Computing Vienna, Austria: R Foundation for Statistical Computing, 2006.
-
(2006)
-
-
-
26
-
-
0031466983
-
From genotypes to genes: Doubling the sample size
-
Sasieni PD. From genotypes to genes: Doubling the sample size. Biometrics 1997 53 : 1253 61.
-
(1997)
Biometrics
, vol.53
, pp. 1253-61
-
-
Sasieni, P.D.1
-
28
-
-
0041857847
-
Pedigree disequilibrium tests for multilocus haplotypes
-
Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003 25 : 115 21.
-
(2003)
Genet Epidemiol
, vol.25
, pp. 115-21
-
-
Dudbridge, F.1
-
30
-
-
41049093347
-
The combination of estimates from different experiments
-
Cochran WG. The combination of estimates from different experiments. Biometrics 1954 10 : 101 29.
-
(1954)
Biometrics
, vol.10
, pp. 101-29
-
-
Cochran, W.G.1
-
31
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002 21 : 1539 58.
-
(2002)
Stat Med
, vol.21
, pp. 1539-58
-
-
Higgins, J.P.1
Thompson, S.G.2
-
32
-
-
33747485574
-
NOD2/CARD15 and toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease
-
Figueroa C, Peralta A, Herrera L, et al. NOD2/CARD15 and toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease. Eur Cytokine Netw 2006 17 : 125 30.
-
(2006)
Eur Cytokine Netw
, vol.17
, pp. 125-30
-
-
Figueroa, C.1
Peralta, A.2
Herrera, L.3
-
33
-
-
23844530641
-
Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients
-
Guo QS, Xia B, Jiang Y, et al. Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients. Postgrad Med J 2005 81 : 526 9.
-
(2005)
Postgrad Med J
, vol.81
, pp. 526-9
-
-
Guo, Q.S.1
Xia, B.2
Jiang, Y.3
-
35
-
-
0002063230
-
A simple classification of Crohn's disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998
-
C, Scholmerich J, Brynskov J, et al. A simple classification of Crohn's disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 2000 6 : 8 15.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 8-15
-
-
Scholmerich, J.1
Brynskov J.et, al.2
-
36
-
-
79959524146
-
A haplotype map of the human genome
-
The International HapMap Consortium.
-
The International HapMap Consortium. A haplotype map of the human genome. Nature 2005 437 : 1299 320.
-
(2005)
Nature
, vol.437
, pp. 1299-320
-
-
-
37
-
-
34247523621
-
The appropriateness of asymmetry tests for publication bias in meta-analyses: A large survey
-
Ioannidis JP, Trikalinos TA. The appropriateness of asymmetry tests for publication bias in meta-analyses: A large survey. CMAJ 2007 176 : 1091 6.
-
(2007)
CMAJ
, vol.176
, pp. 1091-6
-
-
Ioannidis, J.P.1
Trikalinos, T.A.2
-
38
-
-
0029866466
-
Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria
-
Macpherson A, Khoo UY, Forgacs I, et al. Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. Gut 1996 38 : 365 75.
-
(1996)
Gut
, vol.38
, pp. 365-75
-
-
MacPherson, A.1
Khoo, U.Y.2
Forgacs, I.3
-
39
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Backhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 2004 101 : 15718 23.
-
(2004)
Proc Natl Acad Sci U S a
, vol.101
, pp. 15718-23
-
-
Backhed, F.1
Ding, H.2
Wang, T.3
-
41
-
-
0029586031
-
Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
-
Duchmann R, Kaiser I, Hermann E, et al. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995 102 : 448 55.
-
(1995)
Clin Exp Immunol
, vol.102
, pp. 448-55
-
-
Duchmann, R.1
Kaiser, I.2
Hermann, E.3
-
42
-
-
4143069158
-
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
-
Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology 2004 127 : 412 21.
-
(2004)
Gastroenterology
, vol.127
, pp. 412-21
-
-
Darfeuille-Michaud, A.1
Boudeau, J.2
Bulois, P.3
-
43
-
-
0035843993
-
Commensal host-bacterial relationships in the gut
-
Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science 2001 292 : 1115 8.
-
(2001)
Science
, vol.292
, pp. 1115-8
-
-
Hooper, L.V.1
Gordon, J.I.2
-
44
-
-
0031253619
-
The influence of normal microbial flora on the development of chronic mucosal inflammation
-
Sartor RB. The influence of normal microbial flora on the development of chronic mucosal inflammation. Res Immunol 1997 148 : 567 76.
-
(1997)
Res Immunol
, vol.148
, pp. 567-76
-
-
Sartor, R.B.1
-
45
-
-
14544295338
-
Microbes, immunoregulation, and the gut
-
Rook GA, Brunet LR. Microbes, immunoregulation, and the gut. Gut 2005 54 : 317 20.
-
(2005)
Gut
, vol.54
, pp. 317-20
-
-
Rook, G.A.1
Brunet, L.R.2
-
46
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald TT, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005 307 : 1920 5.
-
(2005)
Science
, vol.307
, pp. 1920-5
-
-
MacDonald, T.T.1
Monteleone, G.2
-
47
-
-
34247500287
-
High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease
-
Kotlowski R, Bernstein CN, Sepehri S, et al. High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease. Gut 2007 56 : 669 75.
-
(2007)
Gut
, vol.56
, pp. 669-75
-
-
Kotlowski, R.1
Bernstein, C.N.2
Sepehri, S.3
-
48
-
-
0032692721
-
The intestinal mucus layer from patients with inflammatory bowel disease harbors high numbers of bacteria compared with controls
-
Schultsz C, Van Den Berg FM, Ten Kate FW, et al. The intestinal mucus layer from patients with inflammatory bowel disease harbors high numbers of bacteria compared with controls. Gastroenterology 1999 117 : 1089 97.
-
(1999)
Gastroenterology
, vol.117
, pp. 1089-97
-
-
Schultsz, C.1
Van Den Berg, F.M.2
Ten Kate, F.W.3
-
49
-
-
22644444207
-
Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2
-
Cario E. Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2. Gut 2005 54 : 1182 93.
-
(2005)
Gut
, vol.54
, pp. 1182-93
-
-
Cario, E.1
-
50
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001 411 : 599 603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
51
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000 25 : 187 91.
-
(2000)
Nat Genet
, vol.25
, pp. 187-91
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
-
52
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998 282 : 2085 8.
-
(1998)
Science
, vol.282
, pp. 2085-8
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
53
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 2000 68 : 7010 7.
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7
-
-
Cario, E.1
Podolsky, D.K.2
-
54
-
-
0034858250
-
Excess of rare amino acid polymorphisms in the toll-like receptor 4 in humans
-
Smirnova I, Hamblin MT, McBride C, et al. Excess of rare amino acid polymorphisms in the toll-like receptor 4 in humans. Genetics 2001 158 : 1657 64.
-
(2001)
Genetics
, vol.158
, pp. 1657-64
-
-
Smirnova, I.1
Hamblin, M.T.2
McBride, C.3
-
55
-
-
0036893595
-
Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes
-
Raby BA, Klimecki WT, Laprise C, et al. Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Respir Crit Care Med 2002 166 : 1449 56.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1449-56
-
-
Raby, B.A.1
Klimecki, W.T.2
Laprise, C.3
|