-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S Takeda K Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001 2 : 675 80.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-80
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
0242351615
-
Toll-like receptors and their signaling mechanisms
-
Akira S Sato S. Toll-like receptors and their signaling mechanisms. Scand J Infect Dis 2003 35 : 555 62.
-
(2003)
Scand J Infect Dis
, vol.35
, pp. 555-62
-
-
Akira, S.1
Sato, S.2
-
3
-
-
2342558523
-
Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides
-
Krieg A. Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides. Curr Oncol Rep 2004 6 : 88 95.
-
(2004)
Curr Oncol Rep
, vol.6
, pp. 88-95
-
-
Krieg, A.1
-
4
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki N Ho S Antonenko S et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001 194 : 863 9.
-
(2001)
J Exp Med
, vol.194
, pp. 863-9
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
-
5
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer S Kirschning CJ Hacker H et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA 2001 98 : 9237 42.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9237-42
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
-
6
-
-
0034777579
-
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
-
Krug A Towarowski A Britsch S et al. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol 2001 31 : 3026 37.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3026-37
-
-
Krug, A.1
Towarowski, A.2
Britsch, S.3
-
7
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V Rothenfusser S Britsch S et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002 168 : 4531 7.
-
(2002)
J Immunol
, vol.168
, pp. 4531-7
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
8
-
-
0036318851
-
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
-
Ahmad-Nejad P Hacker H Rutz M Bauer S Vabulas RM Wagner H. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002 32 : 1958 68.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1958-68
-
-
Ahmad-Nejad, P.1
Hacker, H.2
Rutz, M.3
Bauer, S.4
Vabulas, R.M.5
Wagner, H.6
-
9
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz E Schoenemeyer A Visintin A et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 2004 5 : 190 208.
-
(2004)
Nat Immunol
, vol.5
, pp. 190-208
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
-
11
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002 20 : 709 60.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 709-60
-
-
Krieg, A.M.1
-
12
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman DM. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol 2004 4 : 249 58.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 249-58
-
-
Klinman, D.M.1
-
13
-
-
0033546053
-
The nature of the principal type 1 interferon-producing cells in human blood
-
Siegal FP Kadowaki N Shodell M et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 1999 284 : 1835 7.
-
(1999)
Science
, vol.284
, pp. 1835-7
-
-
Siegal, F.P.1
Kadowaki, N.2
Shodell, M.3
-
14
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
-
Krug A Rothenfusser S Hornung V et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol 2001 31 : 2154 63.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2154-63
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
-
15
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Muller U Steinhoff U Reis LF et al. Functional role of type I and type II interferons in antiviral defense. Science 1994 264 : 1918 21.
-
(1994)
Science
, vol.264
, pp. 1918-21
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
-
17
-
-
0034679566
-
Natural interferon alpha/beta-producing cells link innate and adaptive immunity
-
Kadowaki N Antonenko S Lau JY Liu YJ. Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J Exp Med 2000 192 : 219 26.
-
(2000)
J Exp Med
, vol.192
, pp. 219-26
-
-
Kadowaki, N.1
Antonenko, S.2
Lau, J.Y.3
Liu, Y.J.4
-
18
-
-
0036926154
-
Natural type I interferon-producing cells as a link between innate and adaptive immunity
-
Kadowaki N Liu YJ. Natural type I interferon-producing cells as a link between innate and adaptive immunity. Hum Immunol 2002 63 : 1126 32.
-
(2002)
Hum Immunol
, vol.63
, pp. 1126-32
-
-
Kadowaki, N.1
Liu, Y.J.2
-
20
-
-
0031948647
-
Therapeutic applications of CpG-containing oligodeoxynucleotides
-
Klinman DM. Therapeutic applications of CpG-containing oligodeoxynucleotides. Antisense Nucleic Acid Drug Dev 1998 8 : 181 4.
-
(1998)
Antisense Nucleic Acid Drug Dev
, vol.8
, pp. 181-4
-
-
Klinman, D.M.1
-
22
-
-
3142675843
-
CpG-oligonucleotides for cancer immunotherapy: Review of the literature and potential applications in malignant glioma
-
Carpentier AF Auf G Delattre JY. CpG-oligonucleotides for cancer immunotherapy: review of the literature and potential applications in malignant glioma. Front Biosci 2003 8 : e115 27.
-
(2003)
Front Biosci
, vol.8
-
-
Carpentier, A.F.1
Auf, G.2
Delattre, J.Y.3
-
23
-
-
17044447484
-
CpG oligodeoxynucleotides for immune stimulation in cancer immunotherapy
-
Jahrsdorfer B Weiner GJ. CpG oligodeoxynucleotides for immune stimulation in cancer immunotherapy. Curr Opin Investig Drugs 2003 4 : 686 90.
-
(2003)
Curr Opin Investig Drugs
, vol.4
, pp. 686-90
-
-
Jahrsdorfer, B.1
Weiner, G.J.2
-
24
-
-
0033563211
-
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
-
Sur S Wild JS Choudhury BK Sur N Alam R Klinman DM. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol 1999 162 : 6284 93.
-
(1999)
J Immunol
, vol.162
, pp. 6284-93
-
-
Sur, S.1
Wild, J.S.2
Choudhury, B.K.3
Sur, N.4
Alam, R.5
Klinman, D.M.6
-
25
-
-
0032521274
-
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
-
Kline JN Waldschmidt TJ Businga TR et al. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol 1998 160 : 2555 9.
-
(1998)
J Immunol
, vol.160
, pp. 2555-9
-
-
Kline, J.N.1
Waldschmidt, T.J.2
Businga, T.R.3
-
26
-
-
0034827459
-
Immunostimulatory DNA inhibits IL-4-dependent IgE synthesis by human B cells
-
Horner AA Widhopf GF Burger JA et al. Immunostimulatory DNA inhibits IL-4-dependent IgE synthesis by human B cells. J Allergy Clin Immunol 2001 108 : 417 23.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 417-23
-
-
Horner, A.A.1
Widhopf, G.F.2
Burger, J.A.3
-
28
-
-
0032521881
-
CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
-
Zimmermann S Egeter O Hausmann S et al. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J Immunol 1998 160 : 3627 30.
-
(1998)
J Immunol
, vol.160
, pp. 3627-30
-
-
Zimmermann, S.1
Egeter, O.2
Hausmann, S.3
-
29
-
-
0033558121
-
Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria
-
Elkins KL Rhinehart-Jones TR Stibitz S Conover JS Klinman DM. Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J Immunol 1999 162 : 2291 8.
-
(1999)
J Immunol
, vol.162
, pp. 2291-8
-
-
Elkins, K.L.1
Rhinehart-Jones, T.R.2
Stibitz, S.3
Conover, J.S.4
Klinman, D.M.5
-
30
-
-
0034650433
-
CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism
-
Chiaramonte MG Hesse M Cheever AW Wynn TA. CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism. J Immunol 2000 164 : 973 85.
-
(2000)
J Immunol
, vol.164
, pp. 973-85
-
-
Chiaramonte, M.G.1
Hesse, M.2
Cheever, A.W.3
Wynn, T.A.4
-
31
-
-
0033536013
-
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms
-
Walker PS Scharton-Kersten T Krieg AM et al. Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc Natl Acad Sci USA 1999 96 : 6970 5.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6970-5
-
-
Walker, P.S.1
Scharton-Kersten, T.2
Krieg, A.M.3
-
32
-
-
0042208151
-
Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2
-
Ashkar AA Bauer S Mitchell WJ Vieira J Rosenthal KL. Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. J Virol 2003 77 : 8948 56.
-
(2003)
J Virol
, vol.77
, pp. 8948-56
-
-
Ashkar, A.A.1
Bauer, S.2
Mitchell, W.J.3
Vieira, J.4
Rosenthal, K.L.5
-
33
-
-
0034456693
-
Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
-
Du X Poltorak A Wei Y Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 2000 11 : 362 71.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 362-71
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
34
-
-
0034457684
-
Cloning and characterization of a sub-family of human toll-like receptors: HTLR7, hTLR8 and hTLR9
-
Chuang TH Ulevitch RJ. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 2000 11 : 372 8.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 372-8
-
-
Chuang, T.H.1
Ulevitch, R.J.2
-
35
-
-
0037289001
-
Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies
-
Lazarus R Klimecki WT Raby BA et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003 81 : 85 91.
-
(2003)
Genomics
, vol.81
, pp. 85-91
-
-
Lazarus, R.1
Klimecki, W.T.2
Raby, B.A.3
-
36
-
-
1542285261
-
An association study of asthma and total serum immunoglobin e levels for Toll-like receptor polymorphisms in a Japanese population
-
Noguchi E Nishimura F Fukai H et al. An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population. Clin Exp Allergy 2004 34 : 177 83.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 177-83
-
-
Noguchi, E.1
Nishimura, F.2
Fukai, H.3
-
37
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier L Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995 12 : 921 7.
-
(1995)
Mol Biol Evol
, vol.12
, pp. 921-7
-
-
Excoffier, L.1
Slatkin, M.2
-
39
-
-
0036438889
-
CpG motifs as possible adjuvants for the treatment of allergic diseases
-
Bohle B. CpG motifs as possible adjuvants for the treatment of allergic diseases. Int Arch Allergy Immunol 2002 129 : 198 203.
-
(2002)
Int Arch Allergy Immunol
, vol.129
, pp. 198-203
-
-
Bohle, B.1
-
40
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004 5 : 987 95.
-
(2004)
Nat Immunol
, vol.5
, pp. 987-95
-
-
Iwasaki, A.1
Medzhitov, R.2
-
41
-
-
0029934754
-
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
-
Cowdery JS Chace JH Yi AK Krieg AM. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J Immunol 1996 156 : 4570 5.
-
(1996)
J Immunol
, vol.156
, pp. 4570-5
-
-
Cowdery, J.S.1
Chace, J.H.2
Yi, A.K.3
Krieg, A.M.4
-
42
-
-
0030239828
-
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
-
Ballas ZK Rasmussen WL Krieg AM. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol 1996 157 : 1840 5.
-
(1996)
J Immunol
, vol.157
, pp. 1840-5
-
-
Ballas, Z.K.1
Rasmussen, W.L.2
Krieg, A.M.3
-
43
-
-
0031964257
-
CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
-
Davis HL Weeratna R Waldschmidt TJ et al. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol 1998 160 : 870 6.
-
(1998)
J Immunol
, vol.160
, pp. 870-6
-
-
Davis, H.L.1
Weeratna, R.2
Waldschmidt, T.J.3
-
44
-
-
0033485399
-
Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into Th1 effectors
-
Parronchi P Brugnolo F Annunziato F et al. Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into Th1 effectors. J Immunol 1999 163 : 5946 53.
-
(1999)
J Immunol
, vol.163
, pp. 5946-53
-
-
Parronchi, P.1
Brugnolo, F.2
Annunziato, F.3
-
45
-
-
0035184904
-
Type I interferon is required to mount an adaptive response to immunostimulatory DNA
-
Van Uden JH Tran CH Carson DA Raz E. Type I interferon is required to mount an adaptive response to immunostimulatory DNA. Eur J Immunol 2001 31 : 3281 9.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3281-9
-
-
Van Uden, J.H.1
Tran, C.H.2
Carson, D.A.3
Raz, E.4
-
46
-
-
0036118734
-
Atopic phenotype in children is associated with decreased virus-induced interferon-alpha release
-
Bufe A Gehlhar K Grage-Griebenow E Ernst M. Atopic phenotype in children is associated with decreased virus-induced interferon-alpha release. Int Arch Allergy Immunol 2002 127 : 82 8.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 82-8
-
-
Bufe, A.1
Gehlhar, K.2
Grage-Griebenow, E.3
Ernst, M.4
-
47
-
-
0027263737
-
Effects of interferon-alpha-2b on the clinical course, inflammatory skin infiltrates and peripheral blood lymphocytes in patients with severe atopic eczema
-
Gruschwitz MS Peters KP Heese A Stosiek N Koch HU Hornstein OP. Effects of interferon-alpha-2b on the clinical course, inflammatory skin infiltrates and peripheral blood lymphocytes in patients with severe atopic eczema. Int Arch Allergy Immunol 1993 101 : 20 30.
-
(1993)
Int Arch Allergy Immunol
, vol.101
, pp. 20-30
-
-
Gruschwitz, M.S.1
Peters, K.P.2
Heese, A.3
Stosiek, N.4
Koch, H.U.5
Hornstein, O.P.6
-
49
-
-
0037947560
-
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
-
Smirnova I Mann N Dols A et al. Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility. Proc Natl Acad Sci USA 2003 100 : 6075 80.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6075-80
-
-
Smirnova, I.1
Mann, N.2
Dols, A.3
|