-
2
-
-
6044226542
-
Preoperative versus postoperative chemoradiotherapy for rectal cancer
-
Sauer R, Becker H, Hohenberger W, Rodel C, Wittekind C, Fietkau R et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351: 1731-1740.
-
(2004)
N Engl J Med
, vol.351
, pp. 1731-1740
-
-
Sauer, R.1
Becker, H.2
Hohenberger, W.3
Rodel, C.4
Wittekind, C.R.5
Sauer, R.6
Becker, H.7
Hohenberger, W.8
Rodel, C.9
Wittekind, C.R.10
-
3
-
-
38149090400
-
Complete clinical response after preoperative chemoradiation in rectal cancer: Is a wait and see policy justified?
-
discussion 19-20
-
Glynne-Jones R, Wallace M, Livingstone JI, Meyrick-Thomas J. Complete clinical response after preoperative chemoradiation in rectal cancer: is a "wait and see" policy justified? Dis Colon Rectum 2008; 51: 10-19, discussion 19-20.
-
(2008)
Dis Colon Rectum
, vol.51
, pp. 10-19
-
-
Glynne-Jones, R.1
Wallace, M.2
Livingstone, J.I.3
Meyrick-Thomas, J.4
-
4
-
-
34247629347
-
Predictors of tumor response and downstaging in patients who receive preoperative chemoradiation for rectal cancer
-
DOI 10.1002/cncr.22625
-
Das P, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Wolff RA et al. Predictors of tumor response and downstaging in patients who receive pre-operative chemoradiation for rectal cancer. Cancer 2007; 109: 1750-1755. (Pubitemid 46668536)
-
(2007)
Cancer
, vol.109
, Issue.9
, pp. 1750-1755
-
-
Das, P.1
Skibber, J.M.2
Rodrigues-Bigas, M.A.3
Feig, B.W.4
Chang, G.J.5
Wolff, R.A.6
Eng, C.7
Krishnan, S.8
Janjan, N.A.9
Crane, C.H.10
-
5
-
-
84864003865
-
Neoadjuvant treatment response as an early response indicator for patients with rectal cancer
-
Park IJ, You YN, Agarwal A, Skibber JM, Rodriguez-Bigas MA, Eng C et al. Neoadjuvant treatment response as an early response indicator for patients with rectal cancer. J Clin Oncol 2012; 30: 1770-1776.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1770-1776
-
-
Park, I.J.1
You, Y.N.2
Agarwal, A.3
Skibber, J.M.4
Rodriguez-Bigas, M.A.5
Eng, C.6
-
6
-
-
33644842988
-
Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer
-
DOI 10.1200/JCO.2005.02.1329
-
Rodel C, Martus P, Papadoupolos T, Fuzesi L, Klimpfinger M, Fietkau R et al. Prognostic significance of tumor regression after preoperative chemor-adiotherapy for rectal cancer. J Clin Oncol 2005; 23: 8688-8696. (Pubitemid 46211512)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.34
, pp. 8688-8696
-
-
Rodel, C.1
Martus, P.2
Papadoupolos, T.3
Fuzesi, L.4
Klimpfinger, M.5
Fietkau, R.6
Liersch, T.7
Hohenberger, W.8
Raab, R.9
Sauer, R.10
Wittekind, C.11
-
7
-
-
0037083343
-
Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy
-
DOI 10.1002/cncr.10327
-
Bouzourene H, Bosman FT, Seelentag W, Matter M, Coucke P. Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy. Cancer 2002; 94: 1121-1130. (Pubitemid 34150868)
-
(2002)
Cancer
, vol.94
, Issue.4
, pp. 1121-1130
-
-
Bouzourene, H.1
Bosman, F.T.2
Seelentag, W.3
Matter, M.4
Coucke, P.5
-
8
-
-
73349105243
-
Resistance to targeted therapies: Refining anticancer therapy in the era of molecular oncology
-
Ellis LM, Hicklin DJ. Resistance to targeted therapies: refining anticancer therapy in the era of molecular oncology. Clin Cancer Res 2009; 15: 7471-7478.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7471-7478
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
9
-
-
33847327128
-
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
-
Yang AD, Fan F, Camp ER, van Buren G, Liu W, Somcio R et al. Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res 2006; 12(14 Pt 1): 4147-4153.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.14 PART 1
, pp. 4147-4153
-
-
Yang, A.D.1
Fan, F.2
Camp, E.R.3
Van Buren, G.4
Liu, W.5
Somcio, R.6
-
10
-
-
62449205665
-
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
-
Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren II G et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009; 69: 1951-1957.
-
(2009)
Cancer Res
, vol.69
, pp. 1951-1957
-
-
Dallas, N.A.1
Xia, L.2
Fan, F.3
Gray, M.J.4
Gaur, P.5
Van Buren, I.I.G.6
-
11
-
-
84878583653
-
Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like pheno-type in human colorectal cancer cells
-
Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y et al. Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like pheno-type in human colorectal cancer cells. Cancer Med 2012; 1: 5-16.
-
(2012)
Cancer Med
, vol.1
, pp. 5-16
-
-
Fan, F.1
Samuel, S.2
Evans, K.W.3
Lu, J.4
Xia, L.5
Zhou, Y.6
-
12
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
DOI 10.1038/nrm1835, PII NRM1835
-
Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7: 131-142. (Pubitemid 43278296)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.2
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
13
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2000; 2: 84-89.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Dominguez, D.4
Monfar, M.5
Baulida, J.6
-
14
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
Del Barrio, M.G.6
-
15
-
-
0035058012
-
Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer
-
DOI 10.1136/gut.48.3.367
-
Wheeler JM, Kim HC, Efstathiou JA, Ilyas M, Mortensen NJ, Bodmer WF. Hyper-methylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer. Gut 2001; 48: 367-371. (Pubitemid 32269565)
-
(2001)
Gut
, vol.48
, Issue.3
, pp. 367-371
-
-
Wheeler, J.M.D.1
Kim, H.C.2
Efstathiou, J.A.3
Ilyas, M.4
Mortensen, N.J.McC.5
Bodmer, W.F.6
-
16
-
-
13044251809
-
Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells
-
DOI 10.1073/pnas.96.5.2316
-
Efstathiou JA, Liu D, Wheeler JM, Kim HC, Beck NE, Ilyas M et al. Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. Proc Natl Acad Sci USA 1999; 96: 2316-2321. (Pubitemid 29117912)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.5
, pp. 2316-2321
-
-
Efstathiou, J.A.1
Liu, D.2
Wheeler, J.M.D.3
Kim, H.C.4
Beck, N.E.5
Ilyas, M.6
Karayiannakis, A.J.7
Mortensen, N.J.McC.8
Kmiot, W.9
Playford, R.J.10
Pignatelli, M.11
Bodmer, W.F.12
-
17
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil J, Bottinger EP. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005; 24: 5764-5774.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
18
-
-
0035819040
-
Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development
-
DOI 10.1038/sj.onc.1205034
-
Li G, Schaider H, Satyamoorthy K, Hanakawa Y, Hashimoto K, Herlyn M. Down-regulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development. Oncogene 2001; 20: 8125-8135. (Pubitemid 34028337)
-
(2001)
Oncogene
, vol.20
, Issue.56
, pp. 8125-8135
-
-
Li, G.1
Schaider, H.2
Satyamoorthy, K.3
Hanakawa, Y.4
Hashimoto, K.5
Herlyn, M.6
-
19
-
-
0028893391
-
Effect of epidermal growth factor on cadherin-mediated adhesion in a human oeso-phageal cancer cell line
-
Shiozaki H, Kadowaki T, Doki Y, Inoue M, Tamura S, Oka H et al. Effect of epidermal growth factor on cadherin-mediated adhesion in a human oeso-phageal cancer cell line. Br J Cancer 1995; 71: 250-258.
-
(1995)
Br J Cancer
, vol.71
, pp. 250-258
-
-
Shiozaki, H.1
Kadowaki, T.2
Doki, Y.3
Inoue, M.4
Tamura, S.5
Oka, H.6
-
20
-
-
0029806101
-
E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virus- transfected keratinocytes
-
Wilding J, Vousden KH, Soutter WP, McCrea PD, Del Buono R, Pignatelli M. E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virus-transfected kerati-nocytes. Cancer Res 1996; 56: 5285-5292. (Pubitemid 26383049)
-
(1996)
Cancer Research
, vol.56
, Issue.22
, pp. 5285-5292
-
-
Wilding, J.1
Vousden, K.H.2
Soutter, W.P.3
McCrea, P.D.4
Del Buono, R.5
Pignatelli, M.6
-
21
-
-
0026009094
-
Twist and snail as positive and negative regulators during Drosophila mesoderm development
-
Leptin M. twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev 1991; 5: 1568-1576. (Pubitemid 21906062)
-
(1991)
Genes and Development
, vol.5
, Issue.9
, pp. 1568-1576
-
-
Leptin, M.1
-
22
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
23
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20. (Pubitemid 40094598)
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
24
-
-
77649275464
-
MiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
-
Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 2010; 12: 247-256.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 247-256
-
-
Ma, L.1
Young, J.2
Prabhala, H.3
Pan, E.4
Mestdagh, P.5
Muth, D.6
-
25
-
-
79957613439
-
MiR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
-
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH et al. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene 2011; 30: 2463-2474.
-
(2011)
Oncogene
, vol.30
, pp. 2463-2474
-
-
Hwang-Verslues, W.W.1
Chang, P.H.2
Wei, P.C.3
Yang, C.Y.4
Huang, C.K.5
Kuo, W.H.6
-
26
-
-
40349094597
-
MicroRNA-373 induces expression of genes with complementary promoter sequences
-
DOI 10.1073/pnas.0707594105
-
Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci USA 2008; 105: 1608-1613. (Pubitemid 351346562)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1608-1613
-
-
Place, R.F.1
Li, L.-C.2
Pookot, D.3
Noonan, E.J.4
Dahiya, R.5
-
27
-
-
84868206492
-
MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer
-
Cheng CW, Wang HW, Chang CW, Chu HW, Chen CY, Yu JC et al. MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat 2012; 134: 1081-1093.
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 1081-1093
-
-
Cheng, C.W.1
Wang, H.W.2
Chang, C.W.3
Chu, H.W.4
Chen, C.Y.5
Yu, J.C.6
-
28
-
-
84865017512
-
Tumor suppressive microRNA138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma
-
Yamasaki T, Seki N, Yamada Y, Yoshino H, Hidaka H, Chiyomaru T et al. Tumor suppressive microRNA138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. Int J Oncol 2012; 41: 805-817.
-
(2012)
Int J Oncol
, vol.41
, pp. 805-817
-
-
Yamasaki, T.1
Seki, N.2
Yamada, Y.3
Yoshino, H.4
Hidaka, H.5
Chiyomaru, T.6
-
29
-
-
71849092504
-
MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection
-
Zhang X, Ladd A, Dragoescu E, Budd WT, Ware JL, Zehner ZE. MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection. Clin Exp Metastasis 2009; 26: 965-979.
-
(2009)
Clin Exp Metastasis
, vol.26
, pp. 965-979
-
-
Zhang, X.1
Ladd, A.2
Dragoescu, E.3
Budd, W.T.4
Ware, J.L.5
Zehner, Z.E.6
-
30
-
-
84873057723
-
The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer
-
Gao P, Xing AY, Zhou GY, Zhang TG, Zhang JP, Gao C et al. The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. Oncogene 2013; 32: 491-501.
-
(2013)
Oncogene
, vol.32
, pp. 491-501
-
-
Gao, P.1
Xing, A.Y.2
Zhou, G.Y.3
Zhang, T.G.4
Zhang, J.P.5
Gao, C.6
-
31
-
-
78649588750
-
MiR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice
-
Meng Z, Fu X, Chen X, Zeng S, Tian Y, Jove R et al. miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. Hepatol-ogy 2010; 52: 2148-2157.
-
(2010)
Hepatol-ogy
, vol.52
, pp. 2148-2157
-
-
Meng, Z.1
Fu, X.2
Chen, X.3
Zeng, S.4
Tian, Y.5
Jove, R.6
-
32
-
-
84855833376
-
Chemoresistance to 5-fluorouracil induces epithelial-mesenchymal transition via up-regulation of Snail in MCF7 human breast cancer cells
-
Zhang W, Feng M, Zheng G, Chen Y, Wang X, Pen B et al. Chemoresistance to 5-fluorouracil induces epithelial-mesenchymal transition via up-regulation of Snail in MCF7 human breast cancer cells. Biochem Biophys Res Commun 2012; 417: 679-685.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 679-685
-
-
Zhang, W.1
Feng, M.2
Zheng, G.3
Chen, Y.4
Wang, X.5
Pen, B.6
-
33
-
-
84858992906
-
Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells
-
Xia H, Cheung WK, Ng SS, Jiang X, Jiang S, Sze J et al. Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells. J Biol Chem 2012; 287: 9962-9971.
-
(2012)
J Biol Chem
, vol.287
, pp. 9962-9971
-
-
Xia, H.1
Cheung, W.K.2
Ng, S.S.3
Jiang, X.4
Jiang, S.5
Sze, J.6
-
34
-
-
70349145414
-
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
-
Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y et al. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev 2009; 23: 2152-2165.
-
(2009)
Genes Dev
, vol.23
, pp. 2152-2165
-
-
Olson, P.1
Lu, J.2
Zhang, H.3
Shai, A.4
Chun, M.G.5
Wang, Y.6
-
35
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283: 14910-14914.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
36
-
-
84873488599
-
Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression
-
Paterson EL, Kazenwadel J, Bert AG, Khew-Goodall Y, Ruszkiewicz A, Goodall GJ. Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression. Neoplasia 2013; 15: 180-191.
-
(2013)
Neoplasia
, vol.15
, pp. 180-191
-
-
Paterson, E.L.1
Kazenwadel, J.2
Bert, A.G.3
Khew-Goodall, Y.4
Ruszkiewicz, A.5
Goodall, G.J.6
-
37
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
DOI 10.1038/ncb1722, PII NCB1722
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601. (Pubitemid 351627379)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
38
-
-
85011936092
-
The emerging role of miR-200 family of microRNAs in epithelial- mesenchymal transition and cancer metastasis
-
Korpal M, Kang Y. The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biol 2008; 5: 115-119.
-
(2008)
RNA Biol
, vol.5
, pp. 115-119
-
-
Korpal, M.1
Kang, Y.2
-
39
-
-
70450260597
-
Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
-
Arndt GM, Dossey L, Cullen LM, Lai A, Druker R, Eisbacher M et al. Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer 2009; 9: 374.
-
(2009)
BMC Cancer
, vol.9
, pp. 374
-
-
Arndt, G.M.1
Dossey, L.2
Cullen, L.M.3
Lai, A.4
Druker, R.5
Eisbacher, M.6
-
40
-
-
13944260434
-
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
-
DOI 10.1261/rna.7240905
-
Baskerville S, Bartel DP. Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 2005; 11: 241-247. (Pubitemid 40270816)
-
(2005)
RNA
, vol.11
, Issue.3
, pp. 241-247
-
-
Baskerville, S.1
Bartel, D.P.2
-
41
-
-
84866072037
-
Effects of the miR-143/-145 microRNA cluster on the colon cancer proteome and transcriptome
-
Bauer KM, Hummon AB. Effects of the miR-143/-145 microRNA cluster on the colon cancer proteome and transcriptome. J Proteome Res 2012; 11: 4744-4754.
-
(2012)
J Proteome Res
, vol.11
, pp. 4744-4754
-
-
Bauer, K.M.1
Hummon, A.B.2
-
42
-
-
2442705493
-
Snail blocks the cell cycle and confers resistance to cell death
-
DOI 10.1101/gad.294104
-
Vega S, Morales AV, Ocana OH, Valdes F, Fabregat I, Nieto MA. Snail blocks the cell cycle and confers resistance to cell death. Genes Dev 2004; 18: 1131-1143. (Pubitemid 38669034)
-
(2004)
Genes and Development
, vol.18
, Issue.10
, pp. 1131-1143
-
-
Vega, S.1
Morales, A.V.2
Ocana, O.H.3
Valdes, F.4
Fabregat, I.5
Nieto, M.A.6
-
43
-
-
4344662447
-
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
-
DOI 10.1128/MCB.24.17.7559-7566.2004
-
Kajita M, McClinic KN, Wade PA. Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol Cell Biol 2004; 24: 7559-7566. (Pubitemid 39121483)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.17
, pp. 7559-7566
-
-
Kajita, M.1
McClinic, K.N.2
Wade, P.A.3
-
44
-
-
36349006961
-
Development and characterization of gemcitabine-resistant pancreatic tumor cells
-
DOI 10.1245/s10434-007-9583-5
-
Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE. Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol 2007; 14: 3629-3637. (Pubitemid 350160137)
-
(2007)
Annals of Surgical Oncology
, vol.14
, Issue.12
, pp. 3629-3637
-
-
Shah, A.N.1
Summy, J.M.2
Zhang, J.3
Park, S.I.4
Parikh, N.U.5
Gallick, G.E.6
-
45
-
-
34447331032
-
Expression of Snail in Pancreatic Cancer Promotes Metastasis and Chemoresistance
-
DOI 10.1016/j.jss.2006.09.027, PII S0022480406005014
-
Yin T, Wang C, Liu T, Zhao G, Zha Y, Yang M. Expression of snail in pancreatic cancer promotes metastasis and chemoresistance. J Surg Res 2007; 141: 196-203. (Pubitemid 47049639)
-
(2007)
Journal of Surgical Research
, vol.141
, Issue.2
, pp. 196-203
-
-
Yin, T.1
Wang, C.2
Liu, T.3
Zhao, G.4
Zha, Y.5
Yang, M.6
-
46
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
Camp ER, Summy J, Bauer TW, Liu W, Gallick GE, Ellis LM. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clin Cancer Res 2005; 11: 397-405. (Pubitemid 40075820)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.1
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.4
Gallick, G.E.5
Ellis, L.M.6
-
47
-
-
47949089077
-
VEGF-targeted therapy: Mechanisms of anti-tumour activity
-
Ellis LM, Hicklin DJ. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat Rev Cancer 2008; 8: 579-591.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 579-591
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
48
-
-
29344465338
-
Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
-
DOI 10.1158/1078-0432.CCR-05-1492
-
Yauch RL, Januario T, Eberhard DA, Cavet G, Zhu W, Fu L et al. Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients. Clin Cancer Res 2005; 11(24 Pt 1): 8686-8698. (Pubitemid 43005918)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.24
, pp. 8686-8698
-
-
Yauch, R.L.1
Januario, T.2
Eberhard, D.A.3
Cavet, G.4
Zhu, W.5
Fu, L.6
Pham, T.Q.7
Soriano, R.8
Stinson, J.9
Seshagiri, S.10
Modrusan, Z.11
Lin, C.-Y.12
O'Neill, V.13
Amler, L.C.14
-
49
-
-
34250711876
-
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma
-
DOI 10.1158/1535-7163.MCT-07-0138
-
Frederick BA, Helfrich BA, Coldren CD, Zheng D, Chan D, Bunn Jr. PA et al. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol Cancer Ther 2007; 6: 1683-1691. (Pubitemid 46954044)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.6
, pp. 1683-1691
-
-
Frederick, B.A.1
Helfrich, B.A.2
Coldren, C.D.3
Zheng, D.4
Chan, D.5
Bunn Jr., P.A.6
Raben, D.7
-
50
-
-
31544452076
-
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
-
DOI 10.1158/0008-5472.CAN-05-1988
-
Witta SE, Gemmill RM, Hirsch FR, Coldren CD, Hedman K, Ravdel L et al. Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res 2006; 66: 944-950. (Pubitemid 43165962)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 944-950
-
-
Witta, S.E.1
Gemmill, R.M.2
Hirsch, F.R.3
Coldren, C.D.4
Hedman, K.5
Ravdel, L.6
Helfrich, B.7
Dziadziuszko, R.8
Chan, D.C.9
Sugita, M.10
Chan, Z.11
Baron, A.12
Franklin, W.13
Drabkin, H.A.14
Girard, L.15
Gazdar, A.F.16
Minna, J.D.17
Bunn Jr., P.A.18
-
51
-
-
79954434335
-
Chronic exposure of col-orectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration
-
Fan F, Samuel S, Gaur P, Lu J, Dallas NA, Xia L et al. Chronic exposure of col-orectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration. Br J Cancer 2011; 104: 1270-1277.
-
(2011)
Br J Cancer
, vol.104
, pp. 1270-1277
-
-
Fan, F.1
Samuel, S.2
Gaur, P.3
Lu, J.4
Dallas, N.A.5
Xia, L.6
-
52
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
53
-
-
65249182549
-
Isolation and characterization of CD133 cell population within human primary and metastatic colon cancer
-
Puglisi MA, Sgambato A, Saulnier N, Rafanelli F, Barba M, Boninsegna A et al. Isolation and characterization of CD133 cell population within human primary and metastatic colon cancer. Eur Rev Med Pharmacol Sci 2009; 13(Suppl 1)): 55-62.
-
(2009)
Eur Rev Med Pharmacol Sci
, vol.13
, Issue.SUPPL. 1
, pp. 55-62
-
-
Puglisi, M.A.1
Sgambato, A.2
Saulnier, N.3
Rafanelli, F.4
Barba, M.5
Boninsegna, A.6
-
54
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-737. (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
55
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
DOI 10.1038/nature05384, PII NATURE05384
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C et al. Identification and expansion of human colon-cancer-initiating cells. Nature 2007; 445: 111-115. (Pubitemid 46067311)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
56
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
DOI 10.1038/nature05372, PII NATURE05372
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445: 106-110. (Pubitemid 46067310)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
57
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves M, Maley CC. Clonal evolution in cancer. Nature 2012; 481: 306-313.
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
58
-
-
51649111430
-
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
-
Vermeulen L, Todaro M, de Sousa Mello F, Sprick MR, Kemper K, Perez Alea M et al. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci USA 2008; 105: 13427-13432.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13427-13432
-
-
Vermeulen, L.1
Todaro, M.2
De Sousa Mello, F.3
Sprick, M.R.4
Kemper, K.5
Perez Alea, M.6
-
59
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100: 3983-3988. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
60
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
DOI 10.1038/nature03128
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401. (Pubitemid 39551674)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
61
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V et al. Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
-
62
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
DOI 10.1158/0008-5472.CAN-05-0626
-
Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, Coradini D et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 2005; 65: 5506-5511. (Pubitemid 40911148)
-
(2005)
Cancer Research
, vol.65
, Issue.13
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
Coradini, D.6
Pilotti, S.7
Pierotti, M.A.8
Daidone, M.G.9
-
63
-
-
33847419142
-
Molecular Definition of Breast Tumor Heterogeneity
-
DOI 10.1016/j.ccr.2007.01.013, PII S1535610807000293
-
Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J et al. Molecular definition of breast tumor heterogeneity. Cancer Cell 2007; 11: 259-273. (Pubitemid 46349843)
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
Weremowicz, S.4
Bloushtain-Qimron, N.5
Yao, J.6
Nikolskaya, T.7
Serebryiskaya, T.8
Beroukhim, R.9
Hu, M.10
Halushka, M.K.11
Sukumar, S.12
Parker, L.M.13
Anderson, K.S.14
Harris, L.N.15
Garber, J.E.16
Richardson, A.L.17
Schnitt, S.J.18
Nikolsky, Y.19
Gelman, R.S.20
Polyak, K.21
more..
-
64
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9: 265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
65
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
DOI 10.1038/ng.127, PII NG127
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507. (Pubitemid 351601215)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
66
-
-
60949084535
-
Cancer stem cells: A model in the making
-
Marotta LL, Polyak K. Cancer stem cells: a model in the making. Curr Opin Genet Dev 2009; 19: 44-50.
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 44-50
-
-
Marotta, L.L.1
Polyak, K.2
-
67
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
DOI 10.1073/pnas.0703478104
-
Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 2007; 104: 10158-10163. (Pubitemid 47175279)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.-K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
68
-
-
63049115530
-
Phenotypic subpopulations of metastatic colon cancer stem cells: Genomic analysis
-
Botchkina IL, Rowehl RA, Rivadeneira DE, Karpeh Jr. MS, Crawford H, Dufour A et al. Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. Cancer Genomics Proteomics 2009; 6: 19-29.
-
(2009)
Cancer Genomics Proteomics
, vol.6
, pp. 19-29
-
-
Botchkina, I.L.1
Rowehl, R.A.2
Rivadeneira, D.E.3
Karpeh Jr., M.S.4
Crawford, H.5
Dufour, A.6
-
69
-
-
67349149082
-
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
-
Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009; 137: 647-658.
-
(2009)
Cell
, vol.137
, pp. 647-658
-
-
Xu, N.1
Papagiannakopoulos, T.2
Pan, G.3
Thomson, J.A.4
Kosik, K.S.5
-
70
-
-
84878017599
-
Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4
-
Cittelly DM, Finlay-Schultz J, Howe EN, Spoelstra NS, Axlund SD, Hendricks P et al. Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. Oncogene 2013; 32: 2555-2564.
-
(2013)
Oncogene
, vol.32
, pp. 2555-2564
-
-
Cittelly, D.M.1
Finlay-Schultz, J.2
Howe, E.N.3
Spoelstra, N.S.4
Axlund, S.D.5
Hendricks, P.6
-
71
-
-
33747195353
-
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
-
DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676. (Pubitemid 44233629)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
72
-
-
84892729099
-
The stem cell markers Oct4A Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients
-
Di J, Duiveman-de Boer T, Zusterzeel PL, Figdor CG, Massuger LF, Torensma R. The stem cell markers Oct4A, Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients. Cell Oncol (Dordr) 2013; 36: 363-374.
-
(2013)
Cell Oncol (Dordr)
, vol.36
, pp. 363-374
-
-
Di, J.1
Duiveman-De Boer, T.2
Zusterzeel, P.L.3
Figdor, C.G.4
Massuger, L.F.5
Torensma, R.6
-
73
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
DOI 10.1158/0008-5472.CAN-07-2462
-
Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007; 67: 9762-9770. (Pubitemid 47621223)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
Yang, Q.4
Aris, V.5
Soteropoulos, P.6
Petrelli, N.J.7
Dunn, S.P.8
Krueger, L.J.9
-
74
-
-
84855334413
-
MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells
-
Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Deng G et al. MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. PLoS One 2012; 7: e29722.
-
(2012)
PLoS One
, vol.7
-
-
Yamamura, S.1
Saini, S.2
Majid, S.3
Hirata, H.4
Ueno, K.5
Deng, G.6
-
75
-
-
62549148270
-
P53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106: 3207-3212.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
Wu, H.4
Walia, V.5
Kumar, S.6
-
76
-
-
78549269168
-
MiRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
-
Chen Z, Zeng H, Guo Y, Liu P, Pan H, Deng A et al. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Cancer Res 2010; 29: 151.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 151
-
-
Chen, Z.1
Zeng, H.2
Guo, Y.3
Liu, P.4
Pan, H.5
Deng, A.6
-
77
-
-
80054924979
-
MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresis-tance of colorectal cancer stem cells
-
Bitarte N, Bandres E, Boni V, Zarate R, Rodriguez J, Gonzalez-Huarriz M et al. MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresis-tance of colorectal cancer stem cells. Stem Cells 2011; 29: 1661-1671.
-
(2011)
Stem Cells
, vol.29
, pp. 1661-1671
-
-
Bitarte, N.1
Bandres, E.2
Boni, V.3
Zarate, R.4
Rodriguez, J.5
Gonzalez-Huarriz, M.6
-
78
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov 2009; 8: 806-823.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
79
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res 1998; 58: 5337-5339. (Pubitemid 28551112)
-
(1998)
Cancer Research
, vol.58
, Issue.23
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
80
-
-
77955773149
-
Prognostic impact of ALDH1 in breast cancer: A story of stem cells and tumor microenvironment
-
Resetkova E, Reis-Filho JS, Jain RK, Mehta R, Thorat MA, Nakshatri H et al. Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. Breast Cancer Res Treat 2010; 123: 97-108.
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 97-108
-
-
Resetkova, E.1
Reis-Filho, J.S.2
Jain, R.K.3
Mehta, R.4
Thorat, M.A.5
Nakshatri, H.6
-
81
-
-
40549084643
-
IL-4-mediated drug resistance in colon cancer stem cells
-
Todaro M, Perez Alea M, Scopelliti A, Medema JP, Stassi G. IL-4-mediated drug resistance in colon cancer stem cells. Cell Cycle 2008; 7: 309-313. (Pubitemid 351366493)
-
(2008)
Cell Cycle
, vol.7
, Issue.3
, pp. 309-313
-
-
Todaro, M.1
Alea, M.P.2
Scopelliti, A.3
Medema, J.P.4
Stassi, G.5
-
83
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009; 458: 780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
-
84
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
DOI 10.1038/nature05236, PII NATURE05236
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444: 756-760. (Pubitemid 44949604)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
85
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008; 100: 672-679.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
Wu, M.F.6
-
86
-
-
49149107236
-
Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
-
Dylla SJ, Beviglia L, Park IK, Chartier C, Raval J, Ngan L et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One 2008; 3: e2428.
-
(2008)
PLoS One
, vol.3
-
-
Dylla, S.J.1
Beviglia, L.2
Park, I.K.3
Chartier, C.4
Raval, J.5
Ngan, L.6
-
87
-
-
84883424297
-
Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients
-
Giampieri R, Scartozzi M, Loretelli C, Piva F, Mandolesi A, Lezoche G et al. Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients. PLoS One 2013; 8: e72843.
-
(2013)
PLoS One
, vol.8
-
-
Giampieri, R.1
Scartozzi, M.2
Loretelli, C.3
Piva, F.4
Mandolesi, A.5
Lezoche, G.6
-
88
-
-
71549155909
-
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy
-
Saigusa S, Tanaka K, Toiyama Y, Yokoe T, Okugawa Y, Ioue Y et al. Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol 2009; 16: 3488-3498.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 3488-3498
-
-
Saigusa, S.1
Tanaka, K.2
Toiyama, Y.3
Yokoe, T.4
Okugawa, Y.5
Ioue, Y.6
-
89
-
-
43049165453
-
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
90
-
-
33751346643
-
CD44 +/CD24-breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis
-
Sheridan C, Kishimoto H, Fuchs RK, Mehrotra S, Bhat-Nakshatri P, Turner CH et al. CD44 +/CD24-breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res 2006; 8: R59.
-
(2006)
Breast Cancer Res
, vol.8
-
-
Sheridan, C.1
Kishimoto, H.2
Fuchs, R.K.3
Mehrotra, S.4
Bhat-Nakshatri, P.5
Turner, C.H.6
-
91
-
-
77249117415
-
Pancreatic cancer stem cells and EMT in drug resistance and metastasis
-
Sarkar FH, Li Y, Wang Z, Kong D. Pancreatic cancer stem cells and EMT in drug resistance and metastasis. Minerva Chir 2009; 64: 489-500.
-
(2009)
Minerva Chir
, vol.64
, pp. 489-500
-
-
Sarkar, F.H.1
Li, Y.2
Wang, Z.3
Kong, D.4
-
92
-
-
79951813950
-
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
-
Brabletz S, Bajdak K, Meidhof S, Burk U, Niedermann G, Firat E et al. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J 2011; 30: 770-782.
-
(2011)
EMBO J
, vol.30
, pp. 770-782
-
-
Brabletz, S.1
Bajdak, K.2
Meidhof, S.3
Burk, U.4
Niedermann, G.5
Firat, E.6
-
93
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009; 11: 1487-1495.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
-
94
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138: 592-603.
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
-
95
-
-
84865973282
-
An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state
-
Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci USA 2012; 109: 14470-14475.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 14470-14475
-
-
Polytarchou, C.1
Iliopoulos, D.2
Struhl, K.3
-
96
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
DOI 10.1038/nm1483, PII NM1483
-
Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 2006; 12: 1167-1174. (Pubitemid 44527352)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
97
-
-
82755167828
-
Differentiation of breast cancer stem cells by knockdown of CD44: Promising differentiation therapy
-
Pham PV, Phan NL, Nguyen NT, Truong NH, Duong TT, Le DV et al. Differentiation of breast cancer stem cells by knockdown of CD44: promising differentiation therapy. J Transl Med 2011; 9: 209.
-
(2011)
J Transl Med
, vol.9
, pp. 209
-
-
Pham, P.V.1
Phan, N.L.2
Nguyen, N.T.3
Truong, N.H.4
Duong Le, T.T.D.V.5
-
98
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009; 138: 645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
-
99
-
-
70350236538
-
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
-
Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 2009; 69: 7507-7511.
-
(2009)
Cancer Res
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
100
-
-
79955490053
-
Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types
-
Iliopoulos D, Hirsch HA, Struhl K. Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Res 2011; 71: 3196-3201.
-
(2011)
Cancer Res
, vol.71
, pp. 3196-3201
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
101
-
-
33846999327
-
Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracil for patients with advanced or recurrent breast cancer
-
DOI 10.1200/JCO.2006.08.1646
-
Saeki T, Nomizu T, Toi M, Ito Y, Noguchi S, Kobayashi T et al. Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracil for patients with advanced or recurrent breast cancer. J Clin Oncol 2007; 25: 411-417. (Pubitemid 350010637)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.4
, pp. 411-417
-
-
Saeki, T.1
Nomizu, T.2
Toi, M.3
Ito, Y.4
Noguchi, S.5
Kobayashi, T.6
Asaga, T.7
Minami, H.8
Yamamoto, N.9
Aogi, K.10
Ikeda, T.11
Ohashi, Y.12
Sato, W.13
Tsuruo, T.14
-
102
-
-
79551698205
-
A pharma-codynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer
-
Kelly RJ, Draper D, Chen CC, Robey RW, Figg WD, Piekarz RL et al. A pharma-codynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer. Clin Cancer Res 2011; 17: 569-580.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 569-580
-
-
Kelly, R.J.1
Draper, D.2
Chen, C.C.3
Robey, R.W.4
Figg, W.D.5
Piekarz, R.L.6
-
103
-
-
54049115162
-
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer
-
Feldmann G, Fendrich V, McGovern K, Bedja D, Bisht S, Alvarez H et al. An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Mol Cancer Ther 2008; 7: 2725-2735.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2725-2735
-
-
Feldmann, G.1
Fendrich, V.2
McGovern, K.3
Bedja, D.4
Bisht, S.5
Alvarez, H.6
-
104
-
-
79960668961
-
Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer
-
McGowan PM, Simedrea C, Ribot EJ, Foster PJ, Palmieri D, Steeg PS et al. Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer. Mol Cancer Res 2011; 9: 834-844.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 834-844
-
-
McGowan, P.M.1
Simedrea, C.2
Ribot, E.J.3
Foster, P.J.4
Palmieri, D.5
Steeg, P.S.6
-
105
-
-
84860349448
-
A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia
-
Uy GL, Rettig MP, Motabi IH, McFarland K, Trinkaus KM, Hladnik LM et al. A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia. Blood 2012; 119: 3917-3924.
-
(2012)
Blood
, vol.119
, pp. 3917-3924
-
-
Uy, G.L.1
Rettig, M.P.2
Motabi, I.H.3
McFarland, K.4
Trinkaus, K.M.5
Hladnik, L.M.6
|