메뉴 건너뛰기




Volumn 287, Issue 13, 2012, Pages 9962-9971

Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS ANALYSIS; BRAIN TUMORS; CELL FUNCTIONS; CELL MARKERS; CELL SUBPOPULATIONS; EXPERIMENTAL CONFIRMATION; GLIOMA CELL LINES; GLIOMA CELLS; GLIOMA TISSUES; IN-VITRO; IN-VIVO; INHIBITORY EFFECT; INVASIVENESS; MEDULLOBLASTOMA; MICRORNAS; NEURAL DEVELOPMENT; OVER-EXPRESSION; TUMOR SUPPRESSOR ACTIVITY; TUMORIGENICITY;

EID: 84858992906     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.332627     Document Type: Article
Times cited : (155)

References (49)
  • 2
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 4
    • 77949749455 scopus 로고    scopus 로고
    • MicroRNA-induced silencing of glioma progression
    • Wong, J. W. (2010) MicroRNA-induced silencing of glioma progression. J. Neurosci. 30, 3868-3869
    • (2010) J. Neurosci. , vol.30 , pp. 3868-3869
    • Wong, J.W.1
  • 5
    • 65249121446 scopus 로고    scopus 로고
    • Emerging functions of microRNAs in glioblastoma
    • Lawler, S., and Chiocca, E. A. (2009) Emerging functions of microRNAs in glioblastoma. J. Neurooncol. 92, 297-306
    • (2009) J. Neurooncol. , vol.92 , pp. 297-306
    • Lawler, S.1    Chiocca, E.A.2
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D. P. (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 9
    • 27244432205 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Chen, C. Z. (2005) MicroRNAs as oncogenes and tumor suppressors. N. Engl. J. Med. 353, 1768-1771
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1768-1771
    • Chen, C.Z.1
  • 10
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas
    • DOI 10.1158/0008-5472.CAN-07-1045
    • Corsten, M. F., Miranda, R., Kasmieh, R., Krichevsky, A. M., Weissleder, R., and Shah, K. (2007) MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas. Cancer Res. 67, 8994-9000 (Pubitemid 47535880)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 11
    • 77950824571 scopus 로고    scopus 로고
    • Identification and functional characterization of microRNAs involved in the malignant progression of gliomas
    • Bastian, M., Marietta, W., Franziska, L., Michael, G., Kai, S., Helmut, E. M., and Guido, R. (2009) Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol. 20, 539-550
    • (2009) Brain Pathol. , vol.20 , pp. 539-550
    • Bastian, M.1    Marietta, W.2    Franziska, L.3    Michael, G.4    Kai, S.5    Helmut, E.M.6    Guido, R.7
  • 15
    • 77953623899 scopus 로고    scopus 로고
    • MicroRNAs in gliomas: Small regulators of a big problem
    • Silber, J., James, C. D., and Hodgson, J. G. (2009) MicroRNAs in gliomas: small regulators of a big problem. Neuromolecular Med. 11, 208-222
    • (2009) Neuromolecular Med. , vol.11 , pp. 208-222
    • Silber, J.1    James, C.D.2    Hodgson, J.G.3
  • 17
    • 63649138643 scopus 로고    scopus 로고
    • MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • Cheng, L. C., Pastrana, E., Tavazoie, M., and Doetsch, F. (2009) miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 12, 399-408
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, F.4
  • 18
    • 80051684096 scopus 로고    scopus 로고
    • MicroRNA-mediated conversion of human fibroblasts to neurons
    • Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee- Messer, C., Dolmetsch, R. E., Tsien, R. W., and Crabtree, G. R. (2011) MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476, 228-231
    • (2011) Nature , vol.476 , pp. 228-231
    • Yoo, A.S.1    Sun, A.X.2    Li, L.3    Shcheglovitov, A.4    Portmann, T.5    Li, Y.L.-.M.C.D.R.6
  • 19
    • 67349155172 scopus 로고    scopus 로고
    • MiR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1
    • Li, K. K., Pang, J. C., Ching, A. K., Wong, C. K., Kong, X., Wang, Y., Zhou, L., Chen, Z., and Ng, H. K. (2009) miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1. Hum. Pathol. 40, 1234-1243
    • (2009) Hum. Pathol. , vol.40 , pp. 1234-1243
    • Li, K.K.1    Pang, J.C.2    Ching, A.K.3    Wong, C.K.4    Kong, X.5    Wang, Y.6    Zhou, L.7    Chen, Z.8    Ng, H.K.9
  • 20
    • 46349109152 scopus 로고    scopus 로고
    • Regulation of cyclin-dependent kinase 6 by microRNA-124 in medulloblastoma
    • Pierson, J., Hostager, B., Fan, R., and Vibhakar, R. (2008) Regulation of cyclin-dependent kinase 6 by microRNA-124 in medulloblastoma. J. Neurooncol. 90, 1-7
    • (2008) J. Neurooncol. , vol.90 , pp. 1-7
    • Pierson, J.1    Hostager, B.2    Fan, R.3    Vibhakar, R.4
  • 21
    • 25844508786 scopus 로고    scopus 로고
    • The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
    • DOI 10.1038/ng1634, PII N1634
    • Gupta, P. B., Kuperwasser, C., Brunet, J. P., Ramaswamy, S., Kuo, W. L., Gray, J. W., Naber, S. P., and Weinberg, R. A. (2005) The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat. Genet. 37, 1047-1054 (Pubitemid 41486656)
    • (2005) Nature Genetics , vol.37 , Issue.10 , pp. 1047-1054
    • Gupta, P.B.1    Kuperwasser, C.2    Brunet, J.-P.3    Ramaswamy, S.4    Kuo, W.-L.5    Gray, J.W.6    Naber, S.P.7    Weinberg, R.A.8
  • 23
    • 27644448817 scopus 로고    scopus 로고
    • The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
    • DOI 10.1002/cncr.21435
    • Hart, A. H., Hartley, L., Parker, K., Ibrahim, M., Looijenga, L. H., Pauchnik, M., Chow, C. W., and Robb, L. (2005) The pluripotency homeobox gene NANOG is expressed in human germ cell tumors. Cancer 104, 2092-2098 (Pubitemid 41579954)
    • (2005) Cancer , vol.104 , Issue.10 , pp. 2092-2098
    • Hart, A.H.1    Hartley, L.2    Parker, K.3    Ibrahim, M.4    Looijenga, L.H.J.5    Pauchnik, M.6    Chow, C.W.7    Robb, L.8
  • 25
    • 0023103560 scopus 로고
    • Invasiveness of human glioma cell lines in vitro: Relation to tumorigenicity in athymic mice
    • DOI 10.1007/BF00691091
    • de Ridder, L. I., Laerum, O. D., Mørk, S. J., and Bigner, D. D. (1987) Invasiveness of human glioma cell lines in vitro: relation to tumorigenicity in athymic mice. Acta Neuropathol. 72, 207-213 (Pubitemid 17006839)
    • (1987) Acta Neuropathologica , vol.72 , Issue.3 , pp. 207-213
    • De Ridder, L.I.1    Laerum, O.D.2    Mork, S.J.3    Bigner, D.D.4
  • 27
    • 33947180884 scopus 로고    scopus 로고
    • A functional study of miR-124 in the developing neural tube
    • DOI 10.1101/gad.1519207
    • Cao, X., Pfaff, S. L., and Gage, F. H. (2007) A functional study of miR-124 in the developing neural tube. Genes Dev. 21, 531-536 (Pubitemid 46409468)
    • (2007) Genes and Development , vol.21 , Issue.5 , pp. 531-536
    • Cao, X.1    Pfaff, S.L.2    Gage, F.H.3
  • 28
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing
    • DOI 10.1016/j.molcel.2007.07.015, PII S1097276507004881
    • Makeyev, E. V., Zhang, J., Carrasco, M. A., and Maniatis, T. (2007) The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27, 435-448 (Pubitemid 47126944)
    • (2007) Molecular Cell , vol.27 , Issue.3 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 29
    • 63849130585 scopus 로고    scopus 로고
    • Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers
    • Alves, C. C., Carneiro, F., Hoefler, H., and Becker, K. F. (2009) Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. Front. Biosci. 14, 3035-3050
    • (2009) Front. Biosci. , vol.14 , pp. 3035-3050
    • Alves, C.C.1    Carneiro, F.2    Hoefler, H.3    Becker, K.F.4
  • 32
    • 33846184752 scopus 로고    scopus 로고
    • Nanog and transcriptional networks in embryonic stem cell pluripotency
    • DOI 10.1038/sj.cr.7310125, PII 7310125
    • Pan, G., and Thomson, J. A. (2007) Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res. 17, 42-49 (Pubitemid 46096423)
    • (2007) Cell Research , vol.17 , Issue.1 , pp. 42-49
    • Pan, G.1    Thomson, J.A.2
  • 37
    • 70450247130 scopus 로고    scopus 로고
    • Brain tumor stem cells
    • Xie, Z. (2009) Brain tumor stem cells. Neurochem. Res. 34, 2055-2066
    • (2009) Neurochem. Res. , vol.34 , pp. 2055-2066
    • Xie, Z.1
  • 39
    • 77958117982 scopus 로고    scopus 로고
    • MiR-124a is important for migratory cell fate transition during gastrulation of human embryonic stem cells
    • Lee, M. R., Kim, J. S, and Kim, K. S. (2010) miR-124a is important for migratory cell fate transition during gastrulation of human embryonic stem cells. Stem Cells 28, 1550-1559
    • (2010) Stem Cells , vol.28 , pp. 1550-1559
    • Lee, M.R.1    Kim, J.S.2    Kim, K.S.3
  • 41
    • 36048994736 scopus 로고    scopus 로고
    • Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment
    • DOI 10.1093/jnci/djm187
    • Hoelzinger, D. B., Demuth, T., and Berens, M. E. (2007) Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J. Natl. Cancer Inst. 99, 1583-1593 (Pubitemid 351767231)
    • (2007) Journal of the National Cancer Institute , vol.99 , Issue.21 , pp. 1583-1593
    • Hoelzinger, D.B.1    Demuth, T.2    Berens, M.E.3
  • 42
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • DOI 10.1007/s11060-004-2751-6
    • Demuth, T., and Berens, M. E. (2004) Molecular mechanisms of glioma cell migration and invasion. J. Neurooncol. 70, 217-228 (Pubitemid 39545733)
    • (2004) Journal of Neuro-Oncology , vol.70 , Issue.2 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 43
    • 0037379779 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular aspects of cancer invasion
    • Mareel, M., and Leroy, A. (2003) Clinical, cellular, and molecular aspects of cancer invasion. Physiol. Rev. 83, 337-376 (Pubitemid 36382891)
    • (2003) Physiological Reviews , vol.83 , Issue.2 , pp. 337-376
    • Mareel, M.1    Leroy, A.2
  • 44
    • 0034765232 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinases (MT-MMPs): Expression and function during glioma invasion
    • DOI 10.1023/A:1012213604731
    • Fillmore, H. L., VanMeter, T. E., and Broaddus, W. C. (2001) Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion. J. Neurooncol. 53, 187-202 (Pubitemid 33034691)
    • (2001) Journal of Neuro-Oncology , vol.53 , Issue.2 , pp. 187-202
    • Fillmore, H.L.1    VanMeter, T.E.2    Broaddus, W.C.3
  • 46
    • 84855191863 scopus 로고    scopus 로고
    • The putative tumor suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2
    • Zheng, F., Liao, Y. J., Cai, M. Y., Liu, Y. H., Liu, T. H., Chen, S. P., Bian, X. W., Guan, X. Y., Lin, M. C., and Zeng, Y. X. (2012) The putative tumor suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut 61, 278-289
    • (2012) Gut , vol.61 , pp. 278-289
    • Zheng, F.1    Liao, Y.J.2    Cai, M.Y.3    Liu, Y.H.4    Liu, T.H.5    Chen, S.P.6    Bian, X.W.7    Guan, X.Y.8    Lin, M.C.9    Zeng, Y.X.10
  • 48
    • 67949083572 scopus 로고    scopus 로고
    • MicroRNA-mediated switching of chromatin-remodeling complexes in neural development
    • Yoo, A. S., Staahl, B. T., Chen, L., and Crabtree, G. R. (2009) MicroRNA-mediated switching of chromatin-remodeling complexes in neural development. Nature 460, 642-646
    • (2009) Nature , vol.460 , pp. 642-646
    • Yoo, A.S.1    Staahl, B.T.2    Chen, L.3    Crabtree, G.R.4
  • 49
    • 34147157651 scopus 로고    scopus 로고
    • The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
    • DOI 10.1101/gad.1519107
    • Visvanathan, J., Lee, S., Lee, B., Lee, J. W., and Lee, S. K. (2007) The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749 (Pubitemid 46572354)
    • (2007) Genes and Development , vol.21 , Issue.7 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.-K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.