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Volumn 40, Issue 1, 2014, Pages 69-82

Decrease of ERK/MAPK overactivation in prefrontal cortex reverses early memory deficit in a mouse model of alzheimer's disease

Author keywords

3xTg mice; Alzheimer's disease; amyloid aggregation; calcineurin; ERK; JNK; NF B; object recognition memory

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AMYLOID BETA PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; TAU PROTEIN;

EID: 84901777978     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-131076     Document Type: Article
Times cited : (62)

References (71)
  • 1
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ (2001) Alzheimer's disease: Genes, proteins, and therapy. Physiol Rev 81, 741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 4
    • 0035425615 scopus 로고    scopus 로고
    • Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits
    • Stephan A, Laroche S, Davis S (2001) Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J Neurosci 21, 5703-5714.
    • (2001) J Neurosci , vol.21 , pp. 5703-5714
    • Stephan, A.1    Laroche, S.2    Davis, S.3
  • 5
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid beta protein potently inhibit hippocam-pal long-term potentiation in vivo
    • Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ (2002) Naturally secreted oligomers of amyloid beta protein potently inhibit hippocam-pal long-term potentiation in vivo. Nature 416, 535-539.
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 6
    • 0032960305 scopus 로고    scopus 로고
    • Regulation of amyloid precursor protein cleavage
    • Mills J, Reiner PB (1999) Regulation of amyloid precursor protein cleavage. J Neurochem 72, 443-460.
    • (1999) J Neurochem , vol.72 , pp. 443-460
    • Mills, J.1    Reiner, P.B.2
  • 7
    • 0034049944 scopus 로고    scopus 로고
    • Proteolytic processing and cell biological functions of the amyloid precursor protein
    • De Strooper B, Annaert W (2000) Proteolytic processing and cell biological functions of the amyloid precursor protein. J CellSci 113(Pt 11), 1857-1870.
    • (2000) J CellSci , vol.113 , Issue.PART 11 , pp. 1857-1870
    • De Strooper, B.1    Annaert, W.2
  • 11
    • 84655160769 scopus 로고    scopus 로고
    • Amyloid β: Linking synaptic plasticity failure to memory disruption in Alzheimer's disease
    • Ma T, Klann E (2012) Amyloid β: Linking synaptic plasticity failure to memory disruption in Alzheimer's disease. J Neurochem 120(Suppl 1), 140-148.
    • (2012) J Neurochem , vol.120 , Issue.SUPPL. 1 , pp. 140-148
    • Ma, T.1    Klann, E.2
  • 12
    • 0344845132 scopus 로고    scopus 로고
    • Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
    • Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM (2003) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging 24, 1063-1070.
    • (2003) Neurobiol Aging , vol.24 , pp. 1063-1070
    • Oddo, S.1    Caccamo, A.2    Kitazawa, M.3    Tseng, B.P.4    Laferla, F.M.5
  • 15
    • 33846570982 scopus 로고    scopus 로고
    • Learning decreases A beta56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice
    • Billings LM, Green KN, McGaugh JL, LaFerla FM (2007) Learning decreases A beta56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice. J Neurosci 27, 751-761.
    • (2007) J Neurosci , vol.27 , pp. 751-761
    • Billings, L.M.1    Green, K.N.2    McGaugh, J.L.3    Laferla, F.M.4
  • 17
    • 0035875962 scopus 로고    scopus 로고
    • Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
    • Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD (2001) Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21, 4125-4133.
    • (2001) J Neurosci , vol.21 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Ashe, K.H.5    Sweatt, J.D.6
  • 18
    • 0030983079 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
    • Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C (1997) Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc Natl Acad Sci U S A 94, 2642-2647.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2642-2647
    • Kaltschmidt, B.1    Uherek, M.2    Volk, B.3    Baeuerle, P.A.4    Kaltschmidt, C.5
  • 22
    • 0036354603 scopus 로고    scopus 로고
    • Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus
    • Chen Q-S, Wei W-Z, Shimahara T, Xie C-W (2002) Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus. Neurobiol Learn Mem 77, 354-371.
    • (2002) Neurobiol Learn Mem , vol.77 , pp. 354-371
    • Chen, Q.-S.1    Wei, W.-Z.2    Shimahara, T.3    Xie, C.-W.4
  • 23
    • 0038584865 scopus 로고    scopus 로고
    • A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade incultured cortical neurons
    • Fogarty MP, Downer EJ, Campbell V (2003) A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade incultured cortical neurons.Biochem J 371, 789-798.
    • (2003) Biochem J , vol.371 , pp. 789-798
    • Fogarty, M.P.1    Downer, E.J.2    Campbell, V.3
  • 24
    • 0036707528 scopus 로고    scopus 로고
    • Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis
    • Wei W, Norton DD, Wang X, Kusiak JW (2002) Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis. Brain 125, 2036-2043.
    • (2002) Brain , vol.125 , pp. 2036-2043
    • Wei, W.1    Norton, D.D.2    Wang, X.3    Kusiak, J.W.4
  • 26
    • 5444257609 scopus 로고    scopus 로고
    • MAPK recruitment by beta-amyloid in organotypic hip-pocampal slice cultures depends on physical state and exposure time
    • Bell KA, O'Riordan KJ, Sweatt JD, Dineley KT (2004) MAPK recruitment by beta-amyloid in organotypic hip-pocampal slice cultures depends on physical state and exposure time. J Neurochem 91, 349-361.
    • (2004) J Neurochem , vol.91 , pp. 349-361
    • Bell, K.A.1    O'Riordan, K.J.2    Sweatt, J.D.3    Dineley, K.T.4
  • 27
    • 63449094785 scopus 로고    scopus 로고
    • Amyloid beta mediates memory formation
    • Garcia-Osta A, Alberini CM (2009) Amyloid beta mediates memory formation. Learn Mem 16, 267-272.
    • (2009) Learn Mem , vol.16 , pp. 267-272
    • Garcia-Osta, A.1    Alberini, C.M.2
  • 28
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK, Kirschner DA (1990) Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides. Science 250, 279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 29
    • 41849114206 scopus 로고    scopus 로고
    • Effect on memory of acute administration of naturally secreted fibrils and synthetic amyloid-beta peptides in an invertebrate model
    • Feld M, Galli C, Piccini A, Romano A (2008) Effect on memory of acute administration of naturally secreted fibrils and synthetic amyloid-beta peptides in an invertebrate model. Neurobiol Learn Mem 89, 407-418.
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 407-418
    • Feld, M.1    Galli, C.2    Piccini, A.3    Romano, A.4
  • 31
    • 84860889573 scopus 로고    scopus 로고
    • The novel object recognition memory: Neurobiology, test procedure, and its modifications
    • Antunes M, Biala G (2012) The novel object recognition memory: Neurobiology, test procedure, and its modifications. Cogn Process 13, 93-110.
    • (2012) Cogn Process , vol.13 , pp. 93-110
    • Antunes, M.1    Biala, G.2
  • 32
    • 0035228401 scopus 로고    scopus 로고
    • Recognition memory: What are the roles of the perirhinal cortex and hippocampus?
    • Brown MW, Aggleton JP (2001) Recognition memory: What are the roles of the perirhinal cortex and hippocampus? Nat Rev Neurosci 2, 51-61.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 51-61
    • Brown, M.W.1    Aggleton, J.P.2
  • 33
    • 34247574175 scopus 로고    scopus 로고
    • The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
    • Dere E, Huston JP, De Souza Silva MA (2007) The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci Biobehav Rev 31, 673-704.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 673-704
    • Dere, E.1    Huston, J.P.2    De Souza Silva, M.A.3
  • 34
    • 14644442872 scopus 로고    scopus 로고
    • Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
    • Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM (2005) Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45, 675-688.
    • (2005) Neuron , vol.45 , pp. 675-688
    • Billings, L.M.1    Oddo, S.2    Green, K.N.3    McGaugh, J.L.4    Laferla, F.M.5
  • 36
    • 0040246220 scopus 로고    scopus 로고
    • The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans
    • Ö ngür D, Price JL (2000) The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb Cortex 10, 206-219.
    • (2000) Cereb Cortex , vol.10 , pp. 206-219
    • Öngür, D.1    Price, J.L.2
  • 37
    • 33751205344 scopus 로고    scopus 로고
    • Lacorteza prefrontal medial controla el alerta conductual y vegetativo: Implicancias en desórdenes de la conducta
    • Valdés GJL, Torrealba LF (2006) Lacorteza prefrontal medial controla el alerta conductual y vegetativo: Implicancias en desórdenes de la conducta. Rev Chil Neuropsiquiatr 44, 195-204.
    • (2006) Rev Chil Neuropsiquiatr , vol.44 , pp. 195-204
    • Valdés, G.J.L.1    Torrealba, L.F.2
  • 38
    • 2942731425 scopus 로고    scopus 로고
    • CBP histone acetyltransferase activity is a critical component of memory consolidation
    • Korzus E, Rosenfeld MG, Mayford M (2004) CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron 42, 961-972.
    • (2004) Neuron , vol.42 , pp. 961-972
    • Korzus, E.1    Rosenfeld, M.G.2    Mayford, M.3
  • 39
    • 84876543248 scopus 로고    scopus 로고
    • Nuclear factorκB-dependent histone acetylation is specifically involved in persistent forms of memory
    • Federman N, de la Fuente V, Zalcman G, Corbi N, Onori A, Passananti C, Romano A (2013) Nuclear factorκB-dependent histone acetylation is specifically involved in persistent forms of memory. J Neurosci 33, 7603-7614.
    • (2013) J Neurosci , vol.33 , pp. 7603-7614
    • Federman, N.1    De La Fuente, V.2    Zalcman, G.3    Corbi, N.4    Onori, A.5    Passananti, C.6    Romano, A.7
  • 40
    • 0032548758 scopus 로고    scopus 로고
    • Kappa-B like DNA-binding activity is enhanced after spaced training that induces long-term memory in the crab Chasmagnathus
    • Freudenthal R, Locatelli F, Hermitte G, Maldonado H, Lafour-cade C, Delorenzi A, Romano A (1998) Kappa-B like DNA-binding activity is enhanced after spaced training that induces long-term memory in the crab Chasmagnathus. Neu-rosci Lett 242, 143-146.
    • (1998) Neu-rosci Lett , vol.242 , pp. 143-146
    • Freudenthal, R.1    Locatelli, F.2    Hermitte, G.3    Maldonado, H.4    Lafour-Cade, C.5    Delorenzi, A.6    Romano, A.7
  • 41
    • 0034645951 scopus 로고    scopus 로고
    • Participation of Rel/NF-kappaB transcription factors in long-term memory in the crab Chasmagnathus
    • Freudenthal R, Romano A (2000) Participation of Rel/NF-kappaB transcription factors in long-term memory in the crab Chasmagnathus. Brain Res 855, 274-281.
    • (2000) Brain Res , vol.855 , pp. 274-281
    • Freudenthal, R.1    Romano, A.2
  • 42
    • 0037066922 scopus 로고    scopus 로고
    • The IkappaB kinase inhibitor sulfasalazine impairs long-term memory in the crab Chasmagnathus
    • Merlo E, Freudenthal R, Romano A (2002) The IkappaB kinase inhibitor sulfasalazine impairs long-term memory in the crab Chasmagnathus. Neuroscience 112, 161-172.
    • (2002) Neuroscience , vol.112 , pp. 161-172
    • Merlo, E.1    Freudenthal, R.2    Romano, A.3
  • 43
    • 34248679167 scopus 로고    scopus 로고
    • Tricine-SDS-PAGE
    • Schägger H (2006) Tricine-SDS-PAGE. Nat Protoc 1, 16-22.
    • (2006) Nat Protoc , vol.1 , pp. 16-22
    • Schägger, H.1
  • 44
    • 62649147319 scopus 로고    scopus 로고
    • Intermediate-and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition
    • Taglialatela G, Hogan D, Zhang W-R, Dineley KT (2009) Intermediate-and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav Brain Res 200, 95-99.
    • (2009) Behav Brain Res , vol.200 , pp. 95-99
    • Taglialatela, G.1    Hogan, D.2    Zhang, W.-R.3    Dineley, K.T.4
  • 45
    • 25444462744 scopus 로고    scopus 로고
    • Impaired visuospatial recognition memory but normal object novelty detection and relative familiarity judgments in adult mice expressing the APPswe Alzheimer's disease mutation
    • Hale G, Good M (2005) Impaired visuospatial recognition memory but normal object novelty detection and relative familiarity judgments in adult mice expressing the APPswe Alzheimer's disease mutation. Behav Neurosci 119, 884-891.
    • (2005) Behav Neurosci , vol.119 , pp. 884-891
    • Hale, G.1    Good, M.2
  • 46
    • 34249671669 scopus 로고    scopus 로고
    • Impaired "episodic-like" object memory in adult APPswe transgenic mice
    • Good MA, Hale G, Staal V (2007) Impaired "episodic-like" object memory in adult APPswe transgenic mice. Behav Neu-rosci 121, 443-448.
    • (2007) Behav Neu-rosci , vol.121 , pp. 443-448
    • Good, M.A.1    Hale, G.2    Staal, V.3
  • 47
    • 38149078876 scopus 로고    scopus 로고
    • The "swedish" mutation of the amyloid precursor protein (APPswe) dissociates components of object-location memory in aged Tg2576 mice
    • Good MA, Hale G (2007) The "Swedish" mutation of the amyloid precursor protein (APPswe) dissociates components of object-location memory in aged Tg2576 mice. Behav Neu-rosci 121, 1180-1191.
    • (2007) Behav Neu-rosci , vol.121 , pp. 1180-1191
    • Good, M.A.1    Hale, G.2
  • 48
    • 84867641453 scopus 로고    scopus 로고
    • Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease
    • Guzmán-Ramos K, Moreno-Castilla P, Castro-Cruz M, McGaugh JL, Martínez-Coria H, LaFerla FM, Bermúdez-Rattoni F (2012) Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease. Learn Mem 19, 453-460.
    • (2012) Learn Mem , vol.19 , pp. 453-460
    • Guzmán-Ramos, K.1    Moreno-Castilla, P.2    Castro-Cruz, M.3    McGaugh, J.L.4    Martínez-Coria, H.5    Laferla, F.M.6    Bermúdez-Rattoni, F.7
  • 49
    • 33144487701 scopus 로고    scopus 로고
    • Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology
    • Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM (2006) Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J Biol Chem 281, 1599-1604.
    • (2006) J Biol Chem , vol.281 , pp. 1599-1604
    • Oddo, S.1    Caccamo, A.2    Tran, L.3    Lambert, M.P.4    Glabe, C.G.5    Klein, W.L.6    Laferla, F.M.7
  • 51
    • 0041736031 scopus 로고    scopus 로고
    • Prefrontal and medial temporal lobe interactions in long-term memory
    • Simons JS, Spiers HJ (2003) Prefrontal and medial temporal lobe interactions in long-term memory. Nat Rev Neurosci 4, 637-648.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 637-648
    • Simons, J.S.1    Spiers, H.J.2
  • 53
    • 2942550646 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases insynap-tic plasticity and memory
    • Sweatt JD (2004) Mitogen-activated protein kinases insynap-tic plasticity and memory. Curr Opin Neurobiol 14, 311-317.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 311-317
    • Sweatt, J.D.1
  • 54
    • 13444301018 scopus 로고    scopus 로고
    • Phosphorylation of extra-nuclear ERK/MAPK is required for long-term memory consolidation in the crab Chasmagnathus
    • Feld M, Dimant B, Delorenzi A, Coso O, Romano A (2005) Phosphorylation of extra-nuclear ERK/MAPK is required for long-term memory consolidation in the crab Chasmagnathus. Behav Brain Res 158, 251-261.
    • (2005) Behav Brain Res , vol.158 , pp. 251-261
    • Feld, M.1    Dimant, B.2    Delorenzi, A.3    Coso, O.4    Romano, A.5
  • 56
    • 84867641453 scopus 로고    scopus 로고
    • Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease
    • Guzman-Ramos K, Moreno-Castilla P, Castro-Cruz M, McGaugh JL, Martinez-Coria H, LaFerla FM, Bermudez-Rattoni F (2012) Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease. Learn Mem 19, 453-460.
    • (2012) Learn Mem , vol.19 , pp. 453-460
    • Guzman-Ramos, K.1    Moreno-Castilla, P.2    Castro-Cruz, M.3    McGaugh, J.L.4    Martinez-Coria, H.5    Laferla, F.M.6    Bermudez-Rattoni, F.7
  • 57
    • 33947695637 scopus 로고    scopus 로고
    • Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex
    • Nagai T, Takuma K, Kamei H, Ito Y, Nakamichi N, Ibi D, Nakanishi Y, Murai M, Mizoguchi H, Nabeshima T, Yamada K (2007) Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. Learn Mem 14, 117-125.
    • (2007) Learn Mem , vol.14 , pp. 117-125
    • Nagai, T.1    Takuma, K.2    Kamei, H.3    Ito, Y.4    Nakamichi, N.5    Ibi, D.6    Nakanishi, Y.7    Murai, M.8    Mizoguchi, H.9    Nabeshima, T.10    Yamada, K.11
  • 58
    • 84866784086 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated kinase activity improves cognitive function in Tg2576 mice
    • Jin P, Choi D-Y, Hong JT (2012) Inhibition of extracellular signal-regulated kinase activity improves cognitive function in Tg2576 mice. Clin Exp Pharmacol Physiol 39, 852-857.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 852-857
    • Jin, P.1    Choi, D.-Y.2    Hong, J.T.3
  • 59
    • 77955278756 scopus 로고    scopus 로고
    • MEK inhibitors suppress beta-amyloid production by altering the level of a beta-C-terminal fragment of amyloid precursor protein in neuronal cells
    • Araki W, Kametani F, Oda A, Tamaoka A (2010) MEK inhibitors suppress beta-amyloid production by altering the level of a beta-C-terminal fragment of amyloid precursor protein in neuronal cells. FEBS Lett 584, 3410-3414.
    • (2010) FEBS Lett , vol.584 , pp. 3410-3414
    • Araki, W.1    Kametani, F.2    Oda, A.3    Tamaoka, A.4
  • 60
    • 0036458808 scopus 로고    scopus 로고
    • ERK activation and nuclear translocation in amyloid-beta peptide-and iron-stressed neuronal cell cultures
    • Kuperstein F, Yavin E (2002) ERK activation and nuclear translocation in amyloid-beta peptide-and iron-stressed neuronal cell cultures. Eur J Neurosci 16, 44-54.
    • (2002) Eur J Neurosci , vol.16 , pp. 44-54
    • Kuperstein, F.1    Yavin, E.2
  • 61
    • 0032402195 scopus 로고    scopus 로고
    • Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat
    • Berman DE, Hazvi S, Rosenblum K, Seger R, Dudai Y (1998) Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat. J Neurosci 18, 10037-10044.
    • (1998) J Neurosci , vol.18 , pp. 10037-10044
    • Berman, D.E.1    Hazvi, S.2    Rosenblum, K.3    Seger, R.4    Dudai, Y.5
  • 62
    • 0037294435 scopus 로고    scopus 로고
    • Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task
    • Bevilaqua LRM, Kerr DS, Medina JH, Izquierdo I, Cam-marota M (2003) Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task. Eur J Neurosci 17, 897-902.
    • (2003) Eur J Neurosci , vol.17 , pp. 897-902
    • Bevilaqua, L.R.M.1    Kerr, D.S.2    Medina, J.H.3    Izquierdo, I.4    Cam-Marota, M.5
  • 63
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinaseindegenerating neurons in Alzheimer's disease
    • Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA (2001) Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinaseindegenerating neurons in Alzheimer's disease. J Neurochem 76, 435-441.
    • (2001) J Neurochem , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7
  • 64
    • 37149013960 scopus 로고    scopus 로고
    • Activation of hippocampal nuclear factor-kappa B by retrieval is required for memory reconsolidation
    • Boccia M, Freudenthal R, Blake M, de la Fuente V, Acosta G, Baratti C, Romano A (2007) Activation of hippocampal nuclear factor-kappa B by retrieval is required for memory reconsolidation. J Neurosci 27, 13436-13445.
    • (2007) J Neurosci , vol.27 , pp. 13436-13445
    • Boccia, M.1    Freudenthal, R.2    Blake, M.3    De La Fuente, V.4    Acosta, G.5    Baratti, C.6    Romano, A.7
  • 65
    • 34547653708 scopus 로고    scopus 로고
    • Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
    • Dineley KT, Hogan D, Zhang W-R, Taglialatela G (2007) Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice. Neurobiol Learn Mem 88, 217-224.
    • (2007) Neurobiol Learn Mem , vol.88 , pp. 217-224
    • Dineley, K.T.1    Hogan, D.2    Zhang, W.-R.3    Taglialatela, G.4
  • 67
    • 0032498227 scopus 로고    scopus 로고
    • Restricted and regulated overexpression reveals cal-cineurin as a key component in the transition from short-term to long-term memory
    • Mansuy IM, Mayford M, Jacob B, Kandel ER, Bach ME (1998) Restricted and regulated overexpression reveals cal-cineurin as a key component in the transition from short-term to long-term memory. Cell 92, 39-49.
    • (1998) Cell , vol.92 , pp. 39-49
    • Mansuy, I.M.1    Mayford, M.2    Jacob, B.3    Kandel, E.R.4    Bach, M.E.5
  • 68
    • 34547667083 scopus 로고    scopus 로고
    • Beta-amyloid peptide-nicotinic acetylcholine receptor interaction: The two faces of health and disease
    • Dineley KT (2007) Beta-amyloid peptide-nicotinic acetylcholine receptor interaction: The two faces of health and disease. Front Biosci 12, 5030-5038.
    • (2007) Front Biosci , vol.12 , pp. 5030-5038
    • Dineley, K.T.1
  • 69
    • 79955769953 scopus 로고    scopus 로고
    • Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
    • Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ (2011) Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. J Neurosci 31, 6627-6638.
    • (2011) J Neurosci , vol.31 , pp. 6627-6638
    • Li, S.1    Jin, M.2    Koeglsperger, T.3    Shepardson, N.E.4    Shankar, G.M.5    Selkoe, D.J.6
  • 70
    • 80052033738 scopus 로고    scopus 로고
    • Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease
    • Parri HR, Hernandez CM, Dineley KT (2011) Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease. Biochem Pharmacol 82, 931-942.
    • (2011) Biochem Pharmacol , vol.82 , pp. 931-942
    • Parri, H.R.1    Hernandez, C.M.2    Dineley, K.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.