The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner

Journal of Biological Chemistry

Volumn 289, Issue 22, 2014, Pages 15718-15728

  Tarafdar, Sreya ^a,b   Poe, Jerrod A ^a   Smithgall, Thomas E ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

CELL-BASED; COMPLEMENTATION; HIV-1 NEF; HOST CELLS; SELECTIVE INHIBITION; SRC HOMOLOGY 3; THERAPEUTIC BENEFITS; VIRAL LIFE CYCLE;

ENZYMES;

BMS 509744; BMX KINASE; BRUTON TYROSINE KINASE; ENZYME INHIBITOR; ITK KINASE; NEF PROTEIN; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE; TEC KINASE; TXK KINASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; VIRUS INFECTIVITY; VIRUS REPLICATION;

AIDS; HIV-1; NONRECEPTOR TYROSINE KINASE; SH3 DOMAINS; SRC;

AMINO ACID SEQUENCE; ENZYME INHIBITORS; HEK293 CELLS; HIV INFECTIONS; HIV-1; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; SRC HOMOLOGY DOMAINS;

EID: 84901718801     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.572099     Document Type: Article

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