Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions

Journal of Virology

Volumn 74, Issue 11, 2000, Pages 5310-5319

  Liu, Lang Xia ^a   Heveker, Nikolaus ^b   Fackler, Oliver T ^e   Arold, Stefan ^c   Le Gall, Sylvie ^d   Janvier, Katy ^a   Peterlin, B Matija ^e   Dumas, Christian ^c   Schwartz, Olivier ^d   Benichou, Serge ^a   Benarous, Richard ^a  

^a INSTITUT COCHIN   (France)

^b INSERM U 987   (France)

^c INSERM   (France)

^d INSTITUT PASTEUR   (France)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION; OLIGOMERIZATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; VIRUS INFECTIVITY;

AMINO ACID SEQUENCE; ANTIGENS, CD4; CELL MEMBRANE; CONSERVED SEQUENCE; DIMERIZATION; DOWN-REGULATION; GENE PRODUCTS, NEF; HELA CELLS; HIV-1; HLA-A2 ANTIGEN; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; PALMITOYL-COA HYDROLASE; PROTEIN BINDING; PROTEIN CONFORMATION; THIOLESTER HYDROLASES;

EID: 19244382596     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.11.5310-5319.2000     Document Type: Article

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