Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action

Molecular Biology of the Cell

Volumn 21, Issue 19, 2010, Pages 3279-3292

  Dikeakos, Jimmy D ^a   Atkins, Katelyn M ^a   Thomas, Laurel ^a   Emert Sedlak, Lori ^b   Byeon, In Ja L ^b   Jung, Jinwon ^b   Ahn, Jinwoo ^b   Wortman, Matthew D ^c   Kukull, Ben ^d   Saito, Masumichi ^e   Koizumi, Hirokazu ^e   Williamson, Danielle M ^a   Hiyoshi, Masateru ^e   Barklis, Eric ^d   Takiguchi, Masafumi ^e   Suzu, Shinya ^e   Gronenborn, Angela M ^b   Smithgall, Thomas E ^b   Thomas, Gary ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; PROTEIN INHIBITOR; PROTEIN PACS 2; PROTEIN TYROSINE KINASE; SMALL MOLECULE INHIBITOR 2C; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STOICHIOMETRY;

CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DOWN-REGULATION; ENDOCYTOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV-1; HUMANS; MULTIENZYME COMPLEXES; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; SRC-FAMILY KINASES; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; VESICULAR TRANSPORT PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77958041295     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-05-0470     Document Type: Article

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