메뉴 건너뛰기




Volumn 15, Issue 6, 2014, Pages 768-776

Characterization of rare transforming KRAS mutations in sporadic colorectal cancer

Author keywords

Colorectal cancer; KRAS; Targeted therapy

Indexed keywords

PHOSPHATE BINDING PROTEIN; RAS PROTEIN; KRAS PROTEIN, HUMAN; ONCOPROTEIN;

EID: 84901710704     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.28550     Document Type: Article
Times cited : (64)

References (44)
  • 2
    • 77955860591 scopus 로고    scopus 로고
    • EGFR and KRAS in colorectal cancer
    • PMID:20857619
    • Markman B, Javier Ramos F, Capdevila J, Tabernero J. EGFR and KRAS in colorectal cancer. Adv Clin Chem 2010; 51:71-119; PMID:20857619; http://dx.doi.org/10.1016/S0065-2423(10)51004-7
    • (2010) Adv Clin Chem , vol.51 , pp. 71-119
    • Markman, B.1    Javier Ramos, F.2    Capdevila, J.3    Tabernero, J.4
  • 3
    • 84859098993 scopus 로고    scopus 로고
    • KRAS mutant colorectal tumors: Past and present
    • PMID:22714415
    • Brand TM, Wheeler DL. KRAS mutant colorectal tumors: past and present. Small GTPases 2012; 3:34-9; PMID:22714415; http://dx.doi.org/10.4161/sgtp.18751
    • (2012) Small GTPases , vol.3 , pp. 34-39
    • Brand, T.M.1    Wheeler, D.L.2
  • 4
    • 34047248571 scopus 로고    scopus 로고
    • Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
    • PMID:17363584
    • Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, Siena S, Bardelli A. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 2007; 67:2643-8; PMID:17363584; http://dx.doi.org/10.1158/0008-5472.CAN-06-4158
    • (2007) Cancer Res , vol.67 , pp. 2643-2648
    • Benvenuti, S.1    Sartore-Bianchi, A.2    Di Nicolantonio, F.3    Zanon, C.4    Moroni, M.5    Veronese, S.6    Siena, S.7    Bardelli, A.8
  • 5
    • 38649099966 scopus 로고    scopus 로고
    • KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
    • PMID:18202412
    • Lièvre A, Bachet JB, Boige V, Cayre A, Le Corre D, Buc E, Ychou M, Bouché O, Landi B, Louvet C, et al. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol 2008; 26:374-9; PMID:18202412; http://dx.doi.org/10. 1200/JCO.2007.12.5906
    • (2008) J Clin Oncol , vol.26 , pp. 374-379
    • Lièvre, A.1    Bachet, J.B.2    Boige, V.3    Cayre, A.4    Le Corre, D.5    Buc, E.6    Ychou, M.7    Bouché, O.8    Landi, B.9    Louvet, C.10
  • 6
    • 61449154484 scopus 로고    scopus 로고
    • KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: Practical application of patient selection
    • PMID:19124802
    • Jimeno A, Messersmith WA, Hirsch FR, Franklin WA, Eckhardt SG. KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection. J Clin Oncol 2009; 27:1130-6; PMID:19124802; http://dx.doi.org/10.1200/JCO.2008.19.8168
    • (2009) J Clin Oncol , vol.27 , pp. 1130-1136
    • Jimeno, A.1    Messersmith, W.A.2    Hirsch, F.R.3    Franklin, W.A.4    Eckhardt, S.G.5
  • 8
    • 12644273250 scopus 로고    scopus 로고
    • Biochemical characterization of a novel KRAS insertion mutation from a human leukemia
    • PMID:8955068
    • Bollag G, Adler F, elMasry N, McCabe PC, Conner E Jr., Thompson P, McCormick F, Shannon K. Biochemical characterization of a novel KRAS insertion mutation from a human leukemia. J Biol Chem 1996; 271:32491-4; PMID:8955068; http://dx.doi.org/10.1074/jbc.271.51.32491
    • (1996) J Biol Chem , vol.271 , pp. 32491-32494
    • Bollag, G.1    Adler, F.2    ElMasry, N.3    McCabe, P.C.4    Conner Jr., E.5    Thompson, P.6    McCormick, F.7    Shannon, K.8
  • 9
    • 84867117207 scopus 로고    scopus 로고
    • Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with firstline chemotherapy with or without cetuximab
    • PMID:22734028
    • Tejpar S, Celik I, Schlichting M, Sartorius U, Bokemeyer C, Van Cutsem E. Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with firstline chemotherapy with or without cetuximab. J Clin Oncol 2012; 30:3570-7; PMID:22734028; http://dx.doi.org/10. 1200/JCO.2012.42.2592
    • (2012) J Clin Oncol , vol.30 , pp. 3570-3577
    • Tejpar, S.1    Celik, I.2    Schlichting, M.3    Sartorius, U.4    Bokemeyer, C.5    Van Cutsem, E.6
  • 11
    • 0032490124 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The multicenter "RASCAL" study
    • PMID:9586664
    • Andreyev HJ, Norman AR, Cunningham D, Oates JR, Clarke PA. Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study. J Natl Cancer Inst 1998; 90:675-84; PMID:9586664; http://dx.doi.org/10. 1093/jnci/90.9.675
    • (1998) J Natl Cancer Inst , vol.90 , pp. 675-684
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3    Oates, J.R.4    Clarke, P.A.5
  • 12
    • 84855826061 scopus 로고    scopus 로고
    • Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer
    • PMID:22252179
    • Zulhabri O, Rahman J, Ismail S, Isa MR, Wan Zurinah WN. Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer. Singapore Med J 2012; 53:26-31; PMID:22252179
    • (2012) Singapore Med J , vol.53 , pp. 26-31
    • Zulhabri, O.1    Rahman, J.2    Ismail, S.3    Isa, M.R.4    Wan Zurinah, W.N.5
  • 13
    • 30644473641 scopus 로고    scopus 로고
    • Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies
    • PMID:15923428
    • Russo A, Bazan V, Agnese V, Rodolico V, Gebbia N. Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies. Ann Oncol 2005; 16(Suppl 4):iv44-9; PMID:15923428; http://dx.doi.org/10.1093/annonc/mdi907
    • (2005) Ann Oncol , vol.16 , Issue.SUPPL. 4
    • Russo, A.1    Bazan, V.2    Agnese, V.3    Rodolico, V.4    Gebbia, N.5
  • 14
    • 73349114941 scopus 로고    scopus 로고
    • KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: Results from the MRC FOCUS trial
    • PMID:19884549
    • Richman SD, Seymour MT, Chambers P, Elliott F, Daly CL, Meade AM, Taylor G, Barrett JH, Quirke P. KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. J Clin Oncol 2009; 27:5931-7; PMID:19884549; http://dx.doi.org/10.1200/JCO.2009.22.4295
    • (2009) J Clin Oncol , vol.27 , pp. 5931-5937
    • Richman, S.D.1    Seymour, M.T.2    Chambers, P.3    Elliott, F.4    Daly, C.L.5    Meade, A.M.6    Taylor, G.7    Barrett, J.H.8    Quirke, P.9
  • 15
    • 84879074702 scopus 로고    scopus 로고
    • Impact of KRAS Mutation Status on Outcomes in Metastatic Colon Cancer Patients without Anti-Epidermal Growth Factor Receptor Therapy
    • PMID:23613671
    • Kim ST, Park KH, Kim JS, Shin SW, Kim YH. Impact of KRAS Mutation Status on Outcomes in Metastatic Colon Cancer Patients without Anti-Epidermal Growth Factor Receptor Therapy. Cancer Res Treat 2013; 45:55-62; PMID:23613671; http://dx.doi.org/10.4143/crt.2013.45.1.55
    • (2013) Cancer Res Treat , vol.45 , pp. 55-62
    • Kim, S.T.1    Park, K.H.2    Kim, J.S.3    Shin, S.W.4    Kim, Y.H.5
  • 16
    • 84879590699 scopus 로고    scopus 로고
    • KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: A pooled analysis of 12 published trials
    • PMID:23828442
    • Petrelli F, Coinu A, Cabiddu M, Ghilardi M, Barni S. KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: a pooled analysis of 12 published trials. Med Oncol 2013; 30:650; PMID:23828442; http://dx.doi.org/10.1007/s12032-013-0650-4
    • (2013) Med Oncol , vol.30 , pp. 650
    • Petrelli, F.1    Coinu, A.2    Cabiddu, M.3    Ghilardi, M.4    Barni, S.5
  • 17
    • 84880174405 scopus 로고    scopus 로고
    • KRAS mutational status in Japanese patients with colorectal cancer: Results from a nationwide, multicenter, cross-sectional study
    • PMID:23657052
    • Watanabe T, Yoshino T, Uetake H, Yamazaki K, Ishiguro M, Kurokawa T, Saijo N, Ohashi Y, Sugihara K. KRAS mutational status in Japanese patients with colorectal cancer: results from a nationwide, multicenter, cross-sectional study. Jpn J Clin Oncol 2013; 43:706-12; PMID:23657052; http://dx.doi.org/10. 1093/jjco/hyt062
    • (2013) Jpn J Clin Oncol , vol.43 , pp. 706-712
    • Watanabe, T.1    Yoshino, T.2    Uetake, H.3    Yamazaki, K.4    Ishiguro, M.5    Kurokawa, T.6    Saijo, N.7    Ohashi, Y.8    Sugihara, K.9
  • 18
    • 79957576342 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer
    • PMID:21550229
    • Adelstein BA, Dobbins TA, Harris CA, Marschner IC, Ward RL. A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer. Eur J Cancer 2011; 47:1343-54; PMID:21550229; http://dx.doi.org/10.1016/j.ejca.2011.03.031
    • (2011) Eur J Cancer , vol.47 , pp. 1343-1354
    • Adelstein, B.A.1    Dobbins, T.A.2    Harris, C.A.3    Marschner, I.C.4    Ward, R.L.5
  • 19
    • 84860617477 scopus 로고    scopus 로고
    • KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer
    • PMID:22586484
    • Mao C, Zhou J, Yang Z, Huang Y, Wu X, Shen H, Tang J, Chen Q. KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer. PLoS One 2012; 7:e36653; PMID:22586484; http://dx.doi.org/10. 1371/journal.pone.0036653
    • (2012) PLoS One , vol.7
    • Mao, C.1    Zhou, J.2    Yang, Z.3    Huang, Y.4    Wu, X.5    Shen, H.6    Tang, J.7    Chen, Q.8
  • 20
    • 77950936173 scopus 로고    scopus 로고
    • Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer
    • PMID:20184776
    • Yunxia Z, Jun C, Guanshan Z, Yachao L, Xueke Z, Jin L. Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer. BMC Med Genet 2010; 11:34; PMID:20184776; http://dx.doi.org/10.1186/ 1471-2350-11-34
    • (2010) BMC Med Genet , vol.11 , pp. 34
    • Yunxia, Z.1    Jun, C.2    Guanshan, Z.3    Yachao, L.4    Xueke, Z.5    Jin, L.6
  • 21
    • 0033739215 scopus 로고    scopus 로고
    • Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study
    • PMID:11097226
    • Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, Slattery ML. Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev 2000; 9:1193-7; PMID:11097226
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 1193-1197
    • Samowitz, W.S.1    Curtin, K.2    Schaffer, D.3    Robertson, M.4    Leppert, M.5    Slattery, M.L.6
  • 22
    • 0029881739 scopus 로고    scopus 로고
    • C-KI-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas
    • PMID:8814697
    • Elnatan J, Goh HS, Smith DR. C-KI-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas. Eur J Cancer 1996; 32A:491-7; PMID:8814697; http://dx.doi.org/10.1016/0959-8049(95)00567-6
    • (1996) Eur J Cancer , vol.32 A , pp. 491-497
    • Elnatan, J.1    Goh, H.S.2    Smith, D.R.3
  • 23
    • 84878549248 scopus 로고    scopus 로고
    • Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
    • PMID:23348904
    • Rosty C, Young JP, Walsh MD, Clendenning M, Walters RJ, Pearson S, Pavluk E, Nagler B, Pakenas D, Jass JR, et al. Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features. Mod Pathol 2013; 26:825-34; PMID:23348904; http://dx.doi.org/10.1038/modpathol. 2012.240
    • (2013) Mod Pathol , vol.26 , pp. 825-834
    • Rosty, C.1    Young, J.P.2    Walsh, M.D.3    Clendenning, M.4    Walters, R.J.5    Pearson, S.6    Pavluk, E.7    Nagler, B.8    Pakenas, D.9    Jass, J.R.10
  • 24
    • 33747873019 scopus 로고    scopus 로고
    • Distinctive clinicopathological features of Ki-ras mutated colorectal cancers
    • PMID:16900509
    • Lin JK, Chang SC, Wang HS, Yang SH, Jiang JK, Chen WC, Lin TC, Li AF. Distinctive clinicopathological features of Ki-ras mutated colorectal cancers. J Surg Oncol 2006; 94:234-41; PMID:16900509; http://dx.doi.org/10.1002/jso.20438
    • (2006) J Surg Oncol , vol.94 , pp. 234-241
    • Lin, J.K.1    Chang, S.C.2    Wang, H.S.3    Yang, S.H.4    Jiang, J.K.5    Chen, W.C.6    Lin, T.C.7    Li, A.F.8
  • 25
    • 84859885193 scopus 로고    scopus 로고
    • BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: An aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features
    • PMID:22314188
    • Pai RK, Jayachandran P, Koong AC, Chang DT, Kwok S, Ma L, Arber DA, Balise RR, Tubbs RR, Shadrach B, et al. BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features. Am J Surg Pathol 2012; 36:744-52; PMID:22314188; http://dx.doi.org/10.1097/PAS. 0b013e31824430d7
    • (2012) Am J Surg Pathol , vol.36 , pp. 744-752
    • Pai, R.K.1    Jayachandran, P.2    Koong, A.C.3    Chang, D.T.4    Kwok, S.5    Ma, L.6    Arber, D.A.7    Balise, R.R.8    Tubbs, R.R.9    Shadrach, B.10
  • 26
    • 73449128751 scopus 로고    scopus 로고
    • Comparison of 17,641 patients with right- and left-sided colon cancer: Differences in epidemiology, perioperative course, histology, and survival
    • Colon/Rectum Carcinomas (Primary Tumor) Study Group. PMID:20010352
    • Benedix F, Kube R, Meyer F, Schmidt U, Gastinger I, Lippert H; Colon/Rectum Carcinomas (Primary Tumor) Study Group. Comparison of 17,641 patients with right- and left-sided colon cancer: differences in epidemiology, perioperative course, histology, and survival. Dis Colon Rectum 2010; 53:57-64; PMID:20010352; http://dx.doi.org/10.1007/DCR.0b013e3181c703a4
    • (2010) Dis Colon Rectum , vol.53 , pp. 57-64
    • Benedix, F.1    Kube, R.2    Meyer, F.3    Schmidt, U.4    Gastinger, I.5    Lippert, H.6
  • 27
    • 0025048761 scopus 로고
    • Colorectal cancer: Evidence for distinct genetic categories based on proximal or distal tumor location
    • PMID:2240880
    • Bufill JA. Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann Intern Med 1990; 113:779-88; PMID:2240880; http://dx.doi.org/10.7326/0003-4819-113-10-779
    • (1990) Ann Intern Med , vol.113 , pp. 779-788
    • Bufill, J.A.1
  • 28
    • 33744506902 scopus 로고    scopus 로고
    • Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: Proposal for new molecular profile of colorectal carcinomas
    • PMID:16645205
    • Sugai T, Habano W, Jiao YF, Tsukahara M, Takeda Y, Otsuka K, Nakamura S. Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas. J Mol Diagn 2006; 8:193-201; PMID:16645205; http://dx.doi.org/10.2353/jmoldx.2006.050052
    • (2006) J Mol Diagn , vol.8 , pp. 193-201
    • Sugai, T.1    Habano, W.2    Jiao, Y.F.3    Tsukahara, M.4    Takeda, Y.5    Otsuka, K.6    Nakamura, S.7
  • 29
    • 0033815352 scopus 로고    scopus 로고
    • Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation
    • PMID:11044641
    • Soong R, Powell B, Elsaleh H, Gnanasampanthan G, Smith DR, Goh HS, Joseph D, Iacopetta B. Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation. Eur J Cancer 2000; 36:2053-60; PMID:11044641; http:// dx.doi.org/10.1016/S0959-8049(00)00285-9
    • (2000) Eur J Cancer , vol.36 , pp. 2053-2060
    • Soong, R.1    Powell, B.2    Elsaleh, H.3    Gnanasampanthan, G.4    Smith, D.R.5    Goh, H.S.6    Joseph, D.7    Iacopetta, B.8
  • 30
    • 0037057510 scopus 로고    scopus 로고
    • Are there two sides to colorectal cancer?
    • PMID:12216066
    • Iacopetta B. Are there two sides to colorectal cancer? Int J Cancer 2002; 101:403-8; PMID:12216066; http://dx.doi.org/10.1002/ijc.10635
    • (2002) Int J Cancer , vol.101 , pp. 403-408
    • Iacopetta, B.1
  • 33
    • 3142620903 scopus 로고    scopus 로고
    • Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia
    • PMID:14982869
    • Tartaglia M, Martinelli S, Cazzaniga G, Cordeddu V, Iavarone I, Spinelli M, Palmi C, Carta C, Pession A, Aricò M, et al. Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood 2004; 104:307-13; PMID:14982869; http://dx.doi.org/10.1182/blood-2003-11-3876
    • (2004) Blood , vol.104 , pp. 307-313
    • Tartaglia, M.1    Martinelli, S.2    Cazzaniga, G.3    Cordeddu, V.4    Iavarone, I.5    Spinelli, M.6    Palmi, C.7    Carta, C.8    Pession, A.9    Aricò, M.10
  • 34
    • 0033959761 scopus 로고    scopus 로고
    • p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women
    • PMID:10884918
    • Servomaa K, Kiuru A, Kosma VM, Hirvikoski P, Rytömaa T. p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women. Mol Pathol 2000; 53:24-30; PMID:10884918; http://dx.doi.org/10.1136/mp.53.1.24
    • (2000) Mol Pathol , vol.53 , pp. 24-30
    • Servomaa, K.1    Kiuru, A.2    Kosma, V.M.3    Hirvikoski, P.4    Rytömaa, T.5
  • 35
    • 68049088934 scopus 로고    scopus 로고
    • EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
    • PMID:19584155
    • Schmid K, Oehl N, Wrba F, Pirker R, Pirker C, Filipits M. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 2009; 15:4554-60; PMID:19584155; http://dx.doi.org/10.1158/1078-0432.CCR-09-0089
    • (2009) Clin Cancer Res , vol.15 , pp. 4554-4560
    • Schmid, K.1    Oehl, N.2    Wrba, F.3    Pirker, R.4    Pirker, C.5    Filipits, M.6
  • 36
    • 47749128875 scopus 로고    scopus 로고
    • KRAS mutation profile in colorectal carcinoma and novel mutation - Internal tandem duplication in KRAS
    • PMID:18669174
    • Wójcik P, Kulig J, Okoń K, Zazula M, Moździoch I, Niepsuj A, Stachura J. KRAS mutation profile in colorectal carcinoma and novel mutation - internal tandem duplication in KRAS. Pol J Pathol 2008; 59:93-6; PMID:18669174
    • (2008) Pol J Pathol , vol.59 , pp. 93-96
    • Wójcik, P.1    Kulig, J.2    Okoń, K.3    Zazula, M.4    Moździoch, I.5    Niepsuj, A.6    Stachura, J.7
  • 38
    • 77956395148 scopus 로고    scopus 로고
    • Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
    • PMID:20525238
    • Tong JH, Ng DC, Chau SL, So KK, Leung PP, Lee TL, Lung RW, Chan MW, Chan AW, Lo KW, et al. Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. BMC Cancer 2010; 10:253; PMID:20525238; http://dx.doi.org/10.1186/1471-2407-10-253
    • (2010) BMC Cancer , vol.10 , pp. 253
    • Tong, J.H.1    Ng, D.C.2    Chau, S.L.3    So, K.K.4    Leung, P.P.5    Lee, T.L.6    Lung, R.W.7    Chan, M.W.8    Chan, A.W.9    Lo, K.W.10
  • 40
    • 79954627704 scopus 로고    scopus 로고
    • Yesassociated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis
    • PMID:21346147
    • Kang W, Tong JH, Chan AW, Lee TL, Lung RW, Leung PP, So KK, Wu K, Fan D, Yu J, et al. Yesassociated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. Clin Cancer Res 2011; 17:2130-9; PMID:21346147; http://dx.doi.org/10.1158/1078-0432.CCR-10- 2467
    • (2011) Clin Cancer Res , vol.17 , pp. 2130-2139
    • Kang, W.1    Tong, J.H.2    Chan, A.W.3    Lee, T.L.4    Lung, R.W.5    Leung, P.P.6    So, K.K.7    Wu, K.8    Fan, D.9    Yu, J.10
  • 42
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
    • PMID:20619739
    • De Roock W, Claes B, Bernasconi D, De Schutter J, Biesmans B, Fountzilas G, Kalogeras KT, Kotoula V, Papamichael D, Laurent-Puig P, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010; 11:753-62; PMID:20619739; http://dx.doi.org/10.1016/S1470-2045(10)70130-3
    • (2010) Lancet Oncol , vol.11 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3    De Schutter, J.4    Biesmans, B.5    Fountzilas, G.6    Kalogeras, K.T.7    Kotoula, V.8    Papamichael, D.9    Laurent-Puig, P.10
  • 43
    • 67650082332 scopus 로고    scopus 로고
    • Fast simultaneous detection of K-RAS mutations in colorectal cancer
    • PMID:19515263
    • Chang YS, Yeh KT, Chang TJ, Chai C, Lu HC, Hsu NC, Chang JG. Fast simultaneous detection of K-RAS mutations in colorectal cancer. BMC Cancer 2009; 9:179; PMID:19515263; http://dx.doi.org/10.1186/1471-2407-9-179
    • (2009) BMC Cancer , vol.9 , pp. 179
    • Chang, Y.S.1    Yeh, K.T.2    Chang, T.J.3    Chai, C.4    Lu, H.C.5    Hsu, N.C.6    Chang, J.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.