Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers

Clinical Cancer Research

Volumn 18, Issue 17, 2012, Pages 4753-4763

  Imamura, Yu ^a   Morikawa, Teppei ^a   Liao, Xiaoyun ^a   Lochhead, Paul ^a   Kuchiba, Aya ^a   Yamauchi, Mai ^a   Qian, Zhi Rong ^a   Nishihara, Reiko ^a   Meyerhardt, Jeffrey A ^a   Haigis, Kevin M ^c   Fuchs, Charles S ^a,b   Ogino, Shuji ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; K RAS PROTEIN;

ACCURACY; AGED; ARTICLE; BRAF GENE; CANCER GROWTH; CANCER MORTALITY; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CODON; COHORT ANALYSIS; COLON CANCER; COLORECTAL CANCER; CPG ISLAND METHYLATOR PHENOTYPE; FEMALE; GENE; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; LINE 1 GENE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MOLECULAR EPIDEMIOLOGY; MOLECULAR PATHOLOGY; ONCOGENE K RAS; OUTCOME ASSESSMENT; PHENOTYPE; PIK3CA GENE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECTUM CANCER; WILD TYPE;

COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; HUMANS; KAPLAN-MEIER ESTIMATE; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MICROSATELLITE INSTABILITY; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS;

EID: 84865744415     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-3210     Document Type: Article

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