Distinctive clinicopathological features of Ki-ras mutated colorectal cancers

Journal of Surgical Oncology

Volumn 94, Issue 3, 2006, Pages 234-241

  Lin, Jen Kou ^a   Chang, Shih Ching ^a   Wang, Huann Sheng ^a   Yang, Shung Haur ^a   Jiang, Jeng Kai ^a   Chen, Wei Chone ^a   Lin, Tzu Chen ^a   Li, Anna Fen Yau ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Colorectal cancer; Folate; Ki ras

Indexed keywords

FOLIC ACID; MUCIN;

ADULT; AGED; ARTICLE; CANCER GENETICS; CANCER SURVIVAL; CHI SQUARE DISTRIBUTION; CLINICAL FEATURE; CODON; COLORECTAL CANCER; DISEASE FREE SURVIVAL; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; LOG RANK TEST; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; ONCOGENE KI RAS; OUTCOMES RESEARCH; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STUDENT T TEST; TUMOR DIFFERENTIATION;

AGED; CALCIUM; CHI-SQUARE DISTRIBUTION; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; FOLIC ACID; GENE FREQUENCY; GENES, RAS; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS;

EID: 33747873019     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.20438     Document Type: Article

References (43)

1. Vogelstein B, Fearon ER, Hamilton SR, et al.: Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319:525-532.
2. Rashid A, Zahurak M, Goodman SN, et al.: Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas. Gut 1999;44:826-833.
3. Tortola S, Marcuello E, Gonzalez I, et al.: p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer. J Clin Oncol 1999;17:1375-1381.
4. Fearon ER: Molecular genetic studies of the adenoma-carcinoma sequence. Adv Intern Med 1994;39:123-146.
5. Bos JL, Fearon ER, Hamilton ER, et al.: Prevalence of ras mutations in human colorectal cancers. Nature 1987;327:293-297.
6. Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
7. Fujimori T, Satonaka K, Yamamura-Idei Y, et al.: Non-involvement of ras mutations in flat colorectal adenomas and carcinomas. Int J Cancer 1994;57:51-55.
8. Higashidani Y, Tamura S, Morita T, et al.: Analysis of K-ras codon 12 mutation in flat and nodular variants of serrated adenoma in the colon. Dis Colon Rectum 2003;46:327-332.
9. Minamoto T, Sawaguchi K, Mai M, et al.: Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res 1994;54:2841-2844.
10. Ajioka Y, Watanabe H, Jass JR, et al.: Infrequent K-ras codon 12 mutation in serrated adenomas of human colorectum. Gut 1998;42:680-684.
11. Willet WC, Stampfer MJ, Colditz GA, et al.: Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 1990;323:1664-1672.
12. Dol R, Peto R: The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 1987;66:1191-1308.
13. Haenszel W, Kurihara M: Studies of Japanese migrants. Mortality from cancer and other diseases among Japanese in the United States. J Natl Cancer Inst 1968;40:43-68.
14. Bautista D, Obrador A, Moreno V, et al.: Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer. Cancer Epidemiol Biomark Prev 1997;6:57-61.
15. Martinez ME, Maltzman T, Marshall JR, et al.: Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas. Cancer Res 1999;59:5181-5185.
16. Rideout WM 3rd, Coetzee GA, Olumi AF, et al.: 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 1990;249:1288-1290.
17. Shen JC, Rideout WM 3rd, Jones PA: High frequency mutagenesis by a DNA methyltransferase. Cell 1992;71:1073-1080.
18. Herbert V, Nutrition classics: Transactions of the Association of American Physicians, volume 75, 1962, pages 307-320. Experimental nutritional folate deficiency in man. Nutr Rev 1982;40:246-248.
19. Drogan D, Klipstein-Grobusch K, Wans S, et al.: Plasma folate as marker of folate status in epidemiological studies: The European Investigation into Cancer and Nutrition (EPIC)-Potsdam study. Br J Nutr 2004;92:489-496.
20. Compton CC, Fielding LP, Burgart LJ, et al.: Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Path Lab Med 2000;124:979-994.
21. Sobin LH, Wittekind C, editors: "UICC TNM classification of malignant tumors." 5th ed. New York: Wiley-Liss; 1997.
22. Samowitz WS, Curtin K, Schaffer D, et al.: Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study. Cancer Epidemiol Biomarkers Prev 2000;9:1193-1197.
23. Andreyev HJ, Norman AR, Cunningham D, et al.: Kirsten ras mutations in patients with colorectal cancer: The multicenter "RASCAL" study. J Natl Cancer Inst 1998;90:675-684.
24. Beranek M, Bures J, Palicka V, et al.: A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma. Clin Chem Lab Med 1999;37:723-727.
25. Kressner U, Bjorheim J, Westring S, et al.: Ki-ras mutations and prognosis in colorectal cancer. Eur J Cancer 1998;34:518-521.
26. Kastrinakis WV, Ramchurren N, Maggard M, et al.: K-ras status does not predict successful hepatic resection of colorectal cancer metastasis. Arch Surg 1995;130:9-14.
27. Andreyev HJ, Tilsed JV, Cunningham D, et al.: K-ras mutations in patients with early colorectal cancers. Gut 1997;41:323-329.
28. Breivik J, Meling GI, Spurkland A, et al.: K-ras mutation in colorectal cancer: Relations to patient age, sex and tumour location. Br J Cancer 1994;69:367-371.
29. Bazan V, Migliavacca M, Zanna I, et al.: Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype. Ann Oncol 2002;13:1438-1446.
30. Seeburg PH, Colby WW, Capon DJ, et al.: Biological properties of human c-Ha-ras 1 genes mutated at codon 12. Nature 1984;312:71-75.
31. Al-Mulla F, Milner-White EJ, Going JJ, et al.: Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression. J Pathol 1999;187:433-438.
32. Tortola S, Marcuello E, Gonzalez I, et al.: p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer. J Clin Oncol 1999;17:1375-1381.
33. Andreyev HJ, Norman AR, Cunningham D, et al.: Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study. Br J Cancer 2001;85:692-696.
34. Al-Mulla F, Going JJ, Sowden ET, et al.: Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality. J Pathol 1998;185:130-138.
35. Gnanasampanthan G, Elsaleh H, McCaul K, et al.: Ki-ras mutation type and the survival benefit from adjuvant chemotherapy in Dukes' C colorectal cancer. J Pathol 2001;195:543-548.
36. Luna-Perez P, Segura J, Alvarado I, et al.: Specific c-K-ras gene mutations as a tumor-response marker in locally advanced rectal cancer treated with preoperative chemoradiotherapy. Ann Surg Oncol 2000;7:727-731.
37. Konings EJ, Goldbohm RA, Brants HA, et al.: Intake of dietary folate vitamers and risk of colorectal carcinoma: Results from the Netherlands Cohort Study. Cancer (Phila.) 2002;95:1421-1433.
38. Steinmetz KA, Potter JD: Vegetables, fruit, and cancer prevention: A review. J Am Diet Assoc 1996;96:1027-1039.
39. Freudenheim JL, Graham S, Marshall JR, et al.: Folate intake and carcinogenesis of the colon and rectum. Int J Epidemiol 1991;20:368-374.
40. Jacques PF, Sulsky SI, Sadowski JA, et al.: Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient status. Am J Clin Nutr 1993;57:182-189.
41. Green TJ, Allen OB, O'Connor DL: A three-day weighed food record and a semiquantitative food-frequency questionnaire are valid measures for assessing the folate and vitamin B-12 intakes of women aged 16 to 19 years. J Nutr 1998;128:1665-1671.
42. McKinley MC, Strain JJ, McPartlin J, et al.: Plasma homocysteine is not subject to seasonal variation. Clin Chem 2001;47:1430-1436.
43. Melse-Boonstra A, de Bree A, Verhoef P, et al.: Dietary monoglutamate and polyglutamate folate are associated with plasma folate concentrations in Dutch men and women aged 20-65 years. J Nutr 2002;132:1307-1312.