Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

Human Molecular Genetics

Volumn 20, Issue 10, 2011, Pages 1966-1974

  Shi, Guang ^a   Lee, Jeffrey R ^a   Grimes, David A ^d,e   Racacho, Lemuel ^f   Ye, David ^a   Yang, Howard ^d   Ross, Owen A ^b   Farrer, Matthew ^c   McQuibban, G Angus ^a   Bulman, Dennis E ^d,e,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b MAYO GRADUATE SCHOOL   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF OTTAWA   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PRESENILIN; PRESENILIN ASSOCIATED RHOMBOID LIKE PROTEIN; PROTEINASE; PTEN INDUCED KINASE 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; AUTOPHAGY; CATALYSIS; CONTROLLED STUDY; FEMALE; GENE INTERACTION; GENE LOCATION; GENE SEQUENCE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MITOCHONDRION; MOLECULAR GENETICS; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; QUALITY CONTROL; RNA TRANSLATION;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ENZYME STABILITY; FEMALE; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; MALE; METALLOPROTEASES; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PARKINSON DISEASE; PROTEIN KINASES; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; UBIQUITIN-PROTEIN LIGASES;

EID: 79955410000     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr077     Document Type: Article

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